Combined Inhibition of DYRK1A, SMAD, and Trithorax Pathways Synergizes to Induce Robust Replication in Adult Human Beta Cells von Wang, Peng, Karakose, Esra, Liu, Hongtao, Swartz, Ethan, Ackeifi, Courtney, Zlatanic, Viktor, Wilson, Jessica, González, Bryan J., Bender, Aaron, Takane, Karen K., Ye, Lillian, Harb, George, Pagliuca, Felicia, Homann, Dirk, Egli, Dieter, Argmann, Carmen, Scott, Donald K., Garcia-Ocaña, Adolfo, Stewart, Andrew F.

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Disrupting the DREAM complex enables proliferation of adult human pancreatic β cells von Wang, Peng, Karakose, Esra, Argmann, Carmen, Wang, Huan, Balev, Metodi, Brody, Rachel I, Rivas, Hembly G, Liu, Xinyue, Wood, Olivia, Liu, Hongtao, Choleva, Lauryn, Hasson, Dan, Bernstein, Emily, Paulo, Joao A, Scott, Donald K, Lambertini, Luca, DeCaprio, James A, Stewart, Andrew F

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Insights into beta cell regeneration for diabetes via integration of molecular landscapes in human insulinomas von Wang, Huan, Bender, Aaron, Wang, Peng, Karakose, Esra, Inabnet, William B., Libutti, Steven K., Arnold, Andrew, Lambertini, Luca, Stang, Micheal, Chen, Herbert, Kasai, Yumi, Mahajan, Milind, Kinoshita, Yayoi, Fernandez-Ranvier, Gustavo, Becker, Thomas C., Takane, Karen K., Walker, Laura A., Saul, Shira, Chen, Rong, Scott, Donald K., Ferrer, Jorge, Antipin, Yevgeniy, Donovan, Michael, Uzilov, Andrew V., Reva, Boris, Schadt, Eric E., Losic, Bojan, Argmann, Carmen, Stewart, Andrew F.

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Human Beta Cell Regenerative Drug Therapy for Diabetes: Past Achievements and Future Challenges von Wang, Peng, Karakose, Esra, Choleva, Lauryn, Kumar, Kunal, DeVita, Robert J, Garcia-Ocaña, Adolfo, Stewart, Andrew F

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Maladaptive positive feedback production of ChREBPβ underlies glucotoxic β-cell failure von Katz, Liora S., Brill, Gabriel, Zhang, Pili, Kumar, Anil, Baumel-Alterzon, Sharon, Honig, Lee B., Gómez-Banoy, Nicolás, Karakose, Esra, Tanase, Marius, Doridot, Ludivine, Alvarsson, Alexandra, Davenport, Bennett, Wang, Peng, Lambertini, Luca, Stanley, Sarah A., Homann, Dirk, Stewart, Andrew F., Lo, James C., Herman, Mark A., Garcia-Ocaña, Adolfo, Scott, Donald K.

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Aberrant methylation underlies insulin gene expression in human insulinoma von Karakose, Esra, Wang, Huan, Inabnet, William, Thakker, Rajesh V., Libutti, Steven, Fernandez-Ranvier, Gustavo, Suh, Hyunsuk, Stevenson, Mark, Kinoshita, Yayoi, Donovan, Michael, Antipin, Yevgeniy, Li, Yan, Liu, Xiaoxiao, Jin, Fulai, Wang, Peng, Uzilov, Andrew, Argmann, Carmen, Schadt, Eric E., Stewart, Andrew F., Scott, Donald K., Lambertini, Luca

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Author Correction: Maladaptive positive feedback production of ChREBPβ underlies glucotoxic β-cell failure von Katz, Liora S., Brill, Gabriel, Zhang, Pili, Kumar, Anil, Baumel-Alterzon, Sharon, Honig, Lee B., Gómez-Banoy, Nicolás, Karakose, Esra, Tanase, Marius, Doridot, Ludivine, Alvarsson, Alexandra, Davenport, Bennett, Wang, Peng, Lambertini, Luca, Stanley, Sarah A., Homann, Dirk, Stewart, Andrew F., Lo, James C., Herman, Mark A., Garcia-Ocaña, Adolfo, Scott, Donald K.

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The focal adhesion protein PINCH-1 associates with EPLIN at integrin adhesion sites von Karaköse, Esra, Geiger, Tamar, Flynn, Kevin, Lorenz-Baath, Katrin, Zent, Roy, Mann, Matthias, Fässler, Reinhard

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The kindlins at a glance von Karaköse, Esra, Schiller, Herbert B, Fässler, Reinhard

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Crosslinking proteins modulate the self-organization of driven systems von Schaller, Volker, Schmoller, Kurt M., Karaköse, Esra, Hammerich, Benjamin, Maier, Matthias, Bausch, Andreas R.

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PINCH-1 promotes Bcl-2-dependent survival signalling and inhibits JNK-mediated apoptosis in the primitive endoderm von Montanez, Eloi, Karaköse, Esra, Tischner, Denise, Villunger, Andreas, Fässler, Reinhard

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PINCH-1 promotes Bcl-2-dependent survival signalling and inhibits JNK-mediated apoptosis in the primitive endoderm von Montanez, Eloi, Karaköse, Esra, Tischner, Denise, Villunger, Andreas, Fässler, Reinhard

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Advances in drug discovery for human beta cell regeneration von Karakose, Esra, Ackeifi, Courtney, Wang, Peng, Stewart, Andrew F.

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84-OR: Structure–Function Analysis of p57KIP2 in the Human Pancreatic Beta Cell Reveals a Canonical Bipartite Nuclear Localization Sequence (NLS) von CHOLEVA, LAURYN, WANG, PENG, LIU, HONGTAO, WOOD, OLIVIA, LAMBERTINI, LUCA, KARAKOSE, ESRA, STEWART, ANDREW F.

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1720-P: Single Nucleus Transcriptome Profiling of Human Islet Cells under Metabolic Stress In Vivo von KANG, RANDY, LEE, JUNGEUN, VARELA, MIGUEL A., KARAKOSE, ESRA, STEWART, ANDREW F., SCOTT, DONALD, GARCIA-OCANA, ADOLFO, LU, GEMING

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Structure-Function Analysis of p57KIP2 in the Human Pancreatic Beta Cell Reveals a Bipartite Nuclear Localization Signal von Choleva, Lauryn, Wang, Peng, Liu, Hongtao, Wood, Olivia, Lambertini, Luca, Scott, Donald K, Karakose, Esra, Stewart, Andrew F

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Functional characterization of PINCH-1 in embryoid bodies and keratinocytes and identification of new interaction partners von Karaköse, Esra

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349-OR: Selected DYRK1A Inhibitors Simultaneously Drive Both Human Beta-Cell Proliferation and Differentiation von WANG, PENG, KUMAR, KUNAL, LIU, HONGTAO, WOOD, OLIVIA, KARAKOSE, ESRA, CHOLEVA, LAURYN, LAMBERTINI, LUCA, GARCIA-OCANA, ADOLFO, DEVITA, ROBERT J., STEWART, ANDREW F.

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Epigenetic modulation of β cells by interferon-α via PNPT1/mir-26a/TET2 triggers autoimmune diabetes von Stefan-Lifshitz, Mihaela, Karakose, Esra, Cui, Lingguang, Ettela, Abora, Yi, Zhengzi, Zhang, Weijia, Tomer, Yaron

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Disrupting the DREAM complex enables proliferation of adult human pancreatic [beta] cells von Wang, Peng, Karakose, Esra, Argmann, Carmen, Wang, Huan, Balev, Metodi, Brody, Rachel I, Rivas, Hembly G, Liu, Xinyue, Wood, Olivia, Liu, Hongtao, Choleva, Lauryn, Hasson, Dan, Bernstein, Emily, Paulo, Joao A, Scott, Donald K, Lambertini, Luca, DeCaprio, James A, Stewart, Andrew F

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