Expression of mutant Asxl1 perturbs hematopoiesis and promotes susceptibility to leukemic transformation von Nagase, Reina, Inoue, Daichi, Pastore, Alessandro, Fujino, Takeshi, Hou, Hsin-An, Yamasaki, Norimasa, Goyama, Susumu, Saika, Makoto, Kanai, Akinori, Sera, Yasuyuki, Horikawa, Sayuri, Ota, Yasunori, Asada, Shuhei, Hayashi, Yasutaka, Kawabata, Kimihito Cojin, Takeda, Reina, Tien, Hwei-Fang, Honda, Hiroaki, Abdel-Wahab, Omar, Kitamura, Toshio

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Identification of novel methylation markers in HPV-associated oropharyngeal cancer: genome-wide discovery, tissue verification and validation testing in ctDNA von Misawa, Kiyoshi, Imai, Atsushi, Matsui, Hirotaka, Kanai, Akinori, Misawa, Yuki, Mochizuki, Daiki, Mima, Masato, Yamada, Satoshi, Kurokawa, Tomoya, Nakagawa, Takuya, Mineta, Hiroyuki

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Adrenergic receptor signaling induced by Klf15, a regulator of regeneration enhancer, promotes kidney reconstruction von Suzuki, Nanoka, Kanai, Akinori, Suzuki, Yutaka, Ogino, Hajime, Ochi, Haruki

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MOZ/ENL complex is a recruiting factor of leukemic AF10 fusion proteins von Komata, Yosuke, Kanai, Akinori, Maeda, Takahiro, Inaba, Toshiya, Yokoyama, Akihiko

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Overexpression of Hmga2 activates Igf2bp2 and remodels transcriptional program of Tet2-deficient stem cells in myeloid transformation von Bai, Jie, Yokomizo-Nakano, Takako, Kubota, Sho, Sun, Yuqi, Kanai, Akinori, Iimori, Mihoko, Harada, Hironori, Iwama, Atsushi, Sashida, Goro

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Lineage-specific RUNX2 super-enhancer activates MYC and promotes the development of blastic plasmacytoid dendritic cell neoplasm von Kubota, Sho, Tokunaga, Kenji, Umezu, Tomohiro, Yokomizo-Nakano, Takako, Sun, Yuqi, Oshima, Motohiko, Tan, Kar Tong, Yang, Henry, Kanai, Akinori, Iwanaga, Eisaku, Asou, Norio, Maeda, Takahiro, Nakagata, Naomi, Iwama, Atsushi, Ohyashiki, Kazuma, Osato, Motomi, Sashida, Goro

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Age-Dependent Differences in Radiation-Induced DNA Damage Responses in Intestinal Stem Cells von Zhou, Guanyu, Shimura, Tsutomu, Yoneima, Taiki, Nagamachi, Akiko, Kanai, Akinori, Doi, Kazutaka, Sasatani, Megumi

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Ribosome profiling analysis reveals the roles of DDX41 in translational regulation von Tungalag, Saruul, Shinriki, Satoru, Hirayama, Mayumi, Nagamachi, Akiko, Kanai, Akinori, Inaba, Toshiya, Matsui, Hirotaka

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The loss of Ezh2 drives the pathogenesis of myelofibrosis and sensitizes tumor-initiating cells to bromodomain inhibition von Sashida, Goro, Wang, Changshan, Tomioka, Takahisa, Oshima, Motohiko, Aoyama, Kazumasa, Kanai, Akinori, Mochizuki-Kashio, Makiko, Harada, Hironori, Shimoda, Kazuya, Iwama, Atsushi

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HOXA9 promotes MYC-mediated leukemogenesis by maintaining gene expression for multiple anti-apoptotic pathways von Miyamoto, Ryo, Kanai, Akinori, Okuda, Hiroshi, Takahashi, Satoshi, Matsui, Hirotaka, Inaba, Toshiya, Yokoyama, Akihiko, Komata, Yosuke

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GLIS1, a novel hypoxia-inducible transcription factor, promotes breast cancer cell motility via activation of WNT5A von Shimamoto, Kazumi, Tanimoto, Keiji, Fukazawa, Takahiro, Nakamura, Hideaki, Kanai, Akinori, Bono, Hidemasa, Ono, Hiromasa, Eguchi, Hidetaka, Hirohashi, Nobuyuki

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Activation of CpG-Rich Promoters Mediated by MLL Drives MOZ-Rearranged Leukemia von Miyamoto, Ryo, Okuda, Hiroshi, Kanai, Akinori, Takahashi, Satoshi, Kawamura, Takeshi, Matsui, Hirotaka, Kitamura, Toshio, Kitabayashi, Issay, Inaba, Toshiya, Yokoyama, Akihiko

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Phasing analysis of lung cancer genomes using a long read sequencer von Sakamoto, Yoshitaka, Miyake, Shuhei, Oka, Miho, Kanai, Akinori, Kawai, Yosuke, Nagasawa, Satoi, Shiraishi, Yuichi, Tokunaga, Katsushi, Kohno, Takashi, Seki, Masahide, Suzuki, Yutaka, Suzuki, Ayako

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AF4 uses the SL1 components of RNAP1 machinery to initiate MLL fusion- and AEP-dependent transcription von Okuda, Hiroshi, Kanai, Akinori, Ito, Shinji, Matsui, Hirotaka, Yokoyama, Akihiko

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Kinetics of cytokine receptor internalization under steady-state conditions affects growth of neighboring blood cells von Nagamachi, Akiko, Kikuchi, Jiro, Kanai, Akinori, Furukawa, Yusuke, Inaba, Toshiya

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Exposure to microbial products followed by loss of Tet2 promotes myelodysplastic syndrome via remodeling HSCs von Yokomizo-Nakano, Takako, Hamashima, Ai, Kubota, Sho, Bai, Jie, Sorin, Supannika, Sun, Yuqi, Kikuchi, Kenta, Iimori, Mihoko, Morii, Mariko, Kanai, Akinori, Iwama, Atsushi, Huang, Gang, Kurotaki, Daisuke, Takizawa, Hitoshi, Matsui, Hirotaka, Sashida, Goro

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Detection of Pretreatment Circulating Tumor DNA Predicts Recurrence after High-Dose Proton Beam Therapy for Early-Stage Non-Small Cell Lung Cancer von Nakamura, Masaki, Kageyama, Shun-Ichiro, Hirata, Hidenari, Tochinai, Taku, Hojo, Hidehiro, Motegi, Atsushi, Kanai, Akinori, Suzuki, Yutaka, Tsuchihara, Katsuya, Akimoto, Tetsuo

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HBO1-MLL interaction promotes AF4/ENL/P-TEFb-mediated leukemogenesis von Takahashi, Satoshi, Kanai, Akinori, Okuda, Hiroshi, Miyamoto, Ryo, Komata, Yosuke, Kawamura, Takeshi, Matsui, Hirotaka, Inaba, Toshiya, Takaori-Kondo, Akifumi, Yokoyama, Akihiko

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DDX41 coordinates RNA splicing and transcriptional elongation to prevent DNA replication stress in hematopoietic cells von Shinriki, Satoru, Hirayama, Mayumi, Nagamachi, Akiko, Yokoyama, Akihiko, Kawamura, Takeshi, Kanai, Akinori, Kawai, Hidehiko, Iwakiri, Junichi, Liu, Rin, Maeshiro, Manabu, Tungalag, Saruul, Tasaki, Masayoshi, Ueda, Mitsuharu, Tomizawa, Kazuhito, Kataoka, Naoyuki, Ideue, Takashi, Suzuki, Yutaka, Asai, Kiyoshi, Tani, Tokio, Inaba, Toshiya, Matsui, Hirotaka

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Intense Expression of EGFR L858R Characterizes the Micropapillary Component and L858R Is Associated with the Risk of Recurrence in pN0M0 Lung Adenocarcinoma with the Micropapillary... von Kishi, Naoto, Ito, Masaoki, Miyata, Yoshihiro, Kanai, Akinori, Handa, Yoshinori, Tsutani, Yasuhiro, Kushitani, Kei, Takeshima, Yukio, Okada, Morihito

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