E2A-Pbx1, the t(1;19) translocation protein of human pre-B-cell acute lymphocytic leukemia, causes acute myeloid leukemia in mice von KAMPS, M. P, BALTIMORE, D

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E2a-Pbx1 induces aberrant expression of tissue-specific and developmentally regulated genes when expressed in NIH 3T3 fibroblasts von Fu, Xinyu, Kamps, Mark P.

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A conserved motif N-terminal to the DNA-binding domains of myogenic bHLH transcription factors mediates cooperative DNA binding with Pbx-Meis1/Prep1 von Knoepfler, Paul S., Bergstrom, Don A., Uetsuki, Taichi, Dac-Korytko, La, Sun, Y. Henry, Wright, Woodring E., Tapscott, Stephen J., Kamps, Mark P.

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Fusion with E2A converts the Pbx1 homeodomain protein into a constitutive transcriptional activator in human leukemias carrying the t(1;19) translocation von QIANG LU, WRIGHT, D. D, KAMPS, M. P

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Both Pbx1 and E2A-Pbx1 bind the DNA motif ATCAATCAA cooperatively with the products of multiple murine Hox genes, some of which are themselves oncogenes von Lu, Qiang, Knoepfler, Paul S., Scheele, Jurgen, Wright, Dwaine D., Kamps, Mark P.

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Heterodimerization of Hox proteins with Pbx1 and oncoprotein E2a-Pbx1 generates unique DNA-binding specificities at nucleotides predicted to contact the N-terminal arm of the Hox h... von LU, Q, KAMPS, M. P

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The human t(1;19) translocation in pre-B ALL produces multiple nuclear E2A-Pbx1 fusion proteins with differing transforming potentials von KAMPS, M. P, LOOK, A. T, BALTIMORE, D

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Nup98-HoxA9 immortalizes myeloid progenitors, enforces expression of Hoxa9, Hoxa7 and Meis1, and alters cytokine-specific responses in a manner similar to that induced by retrovira... von CALVO, Katherine R, SYKES, David B, PASILLAS, Martina P, KAMPS, Mark P

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Pbx1-Hox Heterodimers Bind DNA on Inseparable Half-Sites That Permit Intrinsic DNA Binding Specificity of the Hox Partner at Nucleotides 3′ to a TAAT Motif von Knoepfler, Paul S., Lu, Qiang, Kamps, Mark P.

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Oncogenic activation of the Lck protein accompanies translocation of the LCK gene in the human HSB2 T-cell leukemia von WRIGHT, D. D, SEFTON, B. M, KAMPS, M. P

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The highest affinity DNA element bound by Pbx complexes in t(1;19) leukemic cells fails to mediate cooperative DNA-binding or cooperative transactivation by E2a-Pbx1 and class I ho... von KNOEPFLER, P. S, KAMPS, M. P

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Meis1a Suppresses Differentiation by G-CSF and Promotes Proliferation by SCF: Potential Mechanisms of Cooperativity with Hoxa9 in Myeloid Leukemia von Calvo, Katherine R., Knoepfler, Paul S., Sykes, David B., Pasillas, Martina P., Kamps, Mark P.

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EB-1, a tyrosine kinase signal transduction gene, is transcriptionally activated in the t(1;19) subset of pre-B ALL, which express oncoprotein E2a-Pbx1 von XINYU FU, MCGRATH, S, PASILLAS, M, NAKAZAWA, S, KAMPS, M. P

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Meis1 and pKnox1 Bind DNA Cooperatively with Pbx1 Utilizing an Interaction Surface Disrupted in Oncoprotein E2a-Pbx1 von Knoepfler, P S, Calvo, K R, Chen, H, Antonarakis, S E, Kamps, M P

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Hoxa9 Immortalizes a Granulocyte-Macrophage Colony-Stimulating Factor-Dependent Promyelocyte Capable of Biphenotypic Differentiation to Neutrophils or Macrophages, Independent of E... von Calvo, Katherine R., Sykes, David B., Pasillas, Martina, Kamps, Mark P.

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Monoclonal antibodies to phosphotyrosine von Glenney, John R., Zokas, Liza, Kamps, Mark P.

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An Induced Ets Repressor Complex Regulates Growth Arrest during Terminal Macrophage Differentiation von Klappacher, Günter W., Lunyak, Victoria V., Sykes, David B., Sawka-Verhelle, Dominique, Sage, Julien, Brard, Gyan, Ngo, Sally D., Gangadharan, Denise, Jacks, Tyler, Kamps, Mark P., Rose, David W., Rosenfeld, Michael G., Glass, Christopher K.

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Myristic acid is attached to the transforming protein of Rous sarcoma virus during or immediately after synthesis and is present in both soluble and membrane-bound forms of the pro... von BUSS, J. E, KAMPS, M. P, SEFTON, B. M

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DIFFERENT MOLECULAR CONSEQUENCES OF THE 1 19 CHROMOSOMAL TRANSLOCATION IN CHILDHOOD B-CELL PRECURSOR ACUTE LYMPHOBLASTIC-LEUKEMIA von PRIVITERA, E, KAMPS, MP, HAYASHI, Y, INABA, T, SHAPIRO, LH, RAIMONDI, SC, BEHM, F, HENDERSHOT, L, CARROLL, AJ, BALTIMORE, D, LOOK, AT

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The absence of myristic acid decreases membrane binding of p60src but does not affect tyrosine protein kinase activity von BUSS, J. E, KAMPS, M. P, GOULD, K, SEFTON, B. M

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