CRISPRi and CRISPRa Screens in Mammalian Cells for Precision Biology and Medicine von Kampmann, Martin

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Elucidating drug targets and mechanisms of action by genetic screens in mammalian cells von Kampmann, Martin

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A CRISPR Approach to Neurodegenerative Diseases von Kampmann, Martin

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Molecular characterization of selectively vulnerable neurons in Alzheimer’s disease von Leng, Kun, Li, Emmy, Eser, Rana, Piergies, Antonia, Sit, Rene, Tan, Michelle, Neff, Norma, Li, Song Hua, Rodriguez, Roberta Diehl, Suemoto, Claudia Kimie, Leite, Renata Elaine Paraizo, Ehrenberg, Alexander J., Pasqualucci, Carlos A., Seeley, William W., Spina, Salvatore, Heinsen, Helmut, Grinberg, Lea T., Kampmann, Martin

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Towards elucidating disease-relevant states of neurons and glia by CRISPR-based functional genomics von Leng, Kun, Kampmann, Martin

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CRISPulator: a discrete simulation tool for pooled genetic screens von Nagy, Tamas, Kampmann, Martin

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CRISPR Interference-Based Platform for Multimodal Genetic Screens in Human iPSC-Derived Neurons von Tian, Ruilin, Gachechiladze, Mariam A., Ludwig, Connor H., Laurie, Matthew T., Hong, Jason Y., Nathaniel, Diane, Prabhu, Anika V., Fernandopulle, Michael S., Patel, Rajan, Abshari, Mehrnoosh, Ward, Michael E., Kampmann, Martin

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Genome-Scale CRISPR-Mediated Control of Gene Repression and Activation von Gilbert, Luke A., Horlbeck, Max A., Adamson, Britt, Villalta, Jacqueline E., Chen, Yuwen, Whitehead, Evan H., Guimaraes, Carla, Panning, Barbara, Ploegh, Hidde L., Bassik, Michael C., Qi, Lei S., Kampmann, Martin, Weissman, Jonathan S.

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Molecular and cellular mechanisms of selective vulnerability in neurodegenerative diseases von Kampmann, Martin

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Compact and highly active next-generation libraries for CRISPR-mediated gene repression and activation von Horlbeck, Max A, Gilbert, Luke A, Villalta, Jacqueline E, Adamson, Britt, Pak, Ryan A, Chen, Yuwen, Fields, Alexander P, Park, Chong Yon, Corn, Jacob E, Kampmann, Martin, Weissman, Jonathan S

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CRISPR-based functional genomics for neurological disease von Kampmann, Martin

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Dual gene activation and knockout screen reveals directional dependencies in genetic networks von Boettcher, Michael, Tian, Ruilin, Blau, James A, Markegard, Evan, Wagner, Ryan T, Wu, David, Mo, Xiulei, Biton, Anne, Zaitlen, Noah, Fu, Haian, McCormick, Frank, Kampmann, Martin, McManus, Michael T

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Mapping the Genetic Landscape of Human Cells von Horlbeck, Max A., Xu, Albert, Wang, Min, Bennett, Neal K., Park, Chong Y., Bogdanoff, Derek, Adamson, Britt, Chow, Eric D., Kampmann, Martin, Peterson, Tim R., Nakamura, Ken, Fischbach, Michael A., Weissman, Jonathan S., Gilbert, Luke A.

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A CRISPRi/a platform in human iPSC-derived microglia uncovers regulators of disease states von Dräger, Nina M., Sattler, Sydney M., Huang, Cindy Tzu-Ling, Teter, Olivia M., Leng, Kun, Hashemi, Sayed Hadi, Hong, Jason, Aviles, Giovanni, Clelland, Claire D., Zhan, Lihong, Udeochu, Joe C., Kodama, Lay, Singleton, Andrew B., Nalls, Mike A., Ichida, Justin, Ward, Michael E., Faghri, Faraz, Gan, Li, Kampmann, Martin

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Probing the Global Cellular Responses to Lipotoxicity Caused by Saturated Fatty Acids von Piccolis, Manuele, Bond, Laura M., Kampmann, Martin, Pulimeno, Pamela, Chitraju, Chandramohan, Jayson, Christina B.K., Vaites, Laura P., Boland, Sebastian, Lai, Zon Weng, Gabriel, Katlyn R., Elliott, Shane D., Paulo, Joao A., Harper, J. Wade, Weissman, Jonathan S., Walther, Tobias C., Farese, Robert V.

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Tau Internalization is Regulated by 6-O Sulfation on Heparan Sulfate Proteoglycans (HSPGs) von Rauch, Jennifer N., Chen, John J., Sorum, Alexander W., Miller, Gregory M., Sharf, Tal, See, Stephanie K., Hsieh-Wilson, Linda C., Kampmann, Martin, Kosik, Kenneth S.

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Targeting the AAA ATPase p97 as an Approach to Treat Cancer through Disruption of Protein Homeostasis von Anderson, Daniel J., Le Moigne, Ronan, Djakovic, Stevan, Kumar, Brajesh, Rice, Julie, Wong, Steve, Wang, Jinhai, Yao, Bing, Valle, Eduardo, Kiss von Soly, Szerenke, Madriaga, Antonett, Soriano, Ferdie, Menon, Mary-Kamala, Wu, Zhi Yong, Kampmann, Martin, Chen, Yuwen, Weissman, Jonathan S., Aftab, Blake T., Yakes, F. Michael, Shawver, Laura, Zhou, Han-Jie, Wustrow, David, Rolfe, Mark

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Three-dimensional structure and flexibility of a membrane-coating module of the nuclear pore complex von Kampmann, Martin, Blobel, Günter

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Integrated platform for genome-wide screening and construction of high-density genetic interaction maps in mammalian cells von Kampmann, Martin, Bassik, Michael C, Weissman, Jonathan S

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Reactive astrocytes transduce inflammation in a blood-brain barrier model through a TNF-STAT3 signaling axis and secretion of alpha 1-antichymotrypsin von Kim, Hyosung, Leng, Kun, Park, Jinhee, Sorets, Alexander G., Kim, Suil, Shostak, Alena, Embalabala, Rebecca J., Mlouk, Kate, Katdare, Ketaki A., Rose, Indigo V. L., Sturgeon, Sarah M., Neal, Emma H., Ao, Yan, Wang, Shinong, Sofroniew, Michael V., Brunger, Jonathan M., McMahon, Douglas G., Schrag, Matthew S., Kampmann, Martin, Lippmann, Ethan S.

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