Cross-ancestry genome-wide analysis of atrial fibrillation unveils disease biology and enables cardioembolic risk prediction von Miyazawa, Kazuo, Ito, Kaoru, Ito, Masamichi, Zou, Zhaonan, Kubota, Masayuki, Nomura, Seitaro, Matsunaga, Hiroshi, Koyama, Satoshi, Ieki, Hirotaka, Akiyama, Masato, Koike, Yoshinao, Kurosawa, Ryo, Yoshida, Hiroki, Ozaki, Kouichi, Onouchi, Yoshihiro, Takahashi, Atsushi, Matsuda, Koichi, Murakami, Yoshinori, Aburatani, Hiroyuki, Kubo, Michiaki, Momozawa, Yukihide, Terao, Chikashi, Oki, Shinya, Akazawa, Hiroshi, Kamatani, Yoichiro, Komuro, Issei

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Mendelian randomization of genetically independent aging phenotypes identifies LPA and VCAM1 as biological targets for human aging von Timmers, Paul R. H. J., Tiys, Evgeny S., Sakaue, Saori, Akiyama, Masato, Kiiskinen, Tuomo T. J., Zhou, Wei, Hwang, Shih-Jen, Yao, Chen, Deelen, Joris, Levy, Daniel, Ganna, Andrea, Kamatani, Yoichiro, Okada, Yukinori, Joshi, Peter K., Wilson, James F., Tsepilov, Yakov A.

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Leveraging fine-mapping and multipopulation training data to improve cross-population polygenic risk scores von Weissbrod, Omer, Kanai, Masahiro, Shi, Huwenbo, Gazal, Steven, Peyrot, Wouter J., Khera, Amit V., Okada, Yukinori, Martin, Alicia R., Finucane, Hilary K., Price, Alkes L.

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Genome-wide meta-analysis identifies 127 open-angle glaucoma loci with consistent effect across ancestries von Gharahkhani, Puya, Jorgenson, Eric, Hysi, Pirro, Khawaja, Anthony P., Pendergrass, Sarah, Han, Xikun, Ong, Jue Sheng, Hewitt, Alex W., Segrè, Ayellet V., Rouhana, John M., Hamel, Andrew R., Igo, Robert P., Choquet, Helene, Qassim, Ayub, Josyula, Navya S., Cooke Bailey, Jessica N., Bonnemaijer, Pieter W. M., Iglesias, Adriana, Siggs, Owen M., Young, Terri L., Vitart, Veronique, Thiadens, Alberta A. H. J., Karjalainen, Juha, Uebe, Steffen, Melles, Ronald B., Nair, K. Saidas, Luben, Robert, Simcoe, Mark, Amersinghe, Nishani, Cree, Angela J., Hohn, Rene, Poplawski, Alicia, Chen, Li Jia, Rong, Shi-Song, Aung, Tin, Vithana, Eranga Nishanthie, Tamiya, Gen, Shiga, Yukihiro, Yamamoto, Masayuki, Nakazawa, Toru, Currant, Hannah, Birney, Ewan, Wang, Xin, Auton, Adam, Lupton, Michelle K., Martin, Nicholas G., Ashaye, Adeyinka, Olawoye, Olusola, Williams, Susan E., Akafo, Stephen, Ramsay, Michele, Hashimoto, Kazuki, Kamatani, Yoichiro, Akiyama, Masato, Momozawa, Yukihide, Foster, Paul J., Khaw, Peng T., Morgan, James E., Strouthidis, Nicholas G., Kraft, Peter, Kang, Jae H., Pang, Chi Pui, Pasutto, Francesca, Mitchell, Paul, Lotery, Andrew J., Palotie, Aarno, van Duijn, Cornelia, Haines, Jonathan L., Hammond, Chris, Pasquale, Louis R., Klaver, Caroline C. W., Hauser, Michael, Khor, Chiea Chuen, Mackey, David A., Kubo, Michiaki, Cheng, Ching-Yu, Craig, Jamie E., MacGregor, Stuart, Wiggs, Janey L.

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Genetics of rheumatoid arthritis contributes to biology and drug discovery von Okada, Yukinori, Wu, Di, Trynka, Gosia, Raj, Towfique, Terao, Chikashi, Ikari, Katsunori, Kochi, Yuta, Ohmura, Koichiro, Suzuki, Akari, Yoshida, Shinji, Graham, Robert R., Manoharan, Arun, Ortmann, Ward, Bhangale, Tushar, Denny, Joshua C., Carroll, Robert J., Eyler, Anne E., Greenberg, Jeffrey D., Kremer, Joel M., Pappas, Dimitrios A., Jiang, Lei, Yin, Jian, Ye, Lingying, Su, Ding-Feng, Yang, Jian, Xie, Gang, Keystone, Ed, Westra, Harm-Jan, Esko, Tõnu, Metspalu, Andres, Zhou, Xuezhong, Gupta, Namrata, Mirel, Daniel, Stahl, Eli A., Diogo, Dorothée, Cui, Jing, Liao, Katherine, Guo, Michael H., Myouzen, Keiko, Kawaguchi, Takahisa, Coenen, Marieke J. H., van Riel, Piet L. C. M., van de Laar, Mart A. F. J., Guchelaar, Henk-Jan, Huizinga, Tom W. J., Dieudé, Philippe, Mariette, Xavier, Louis Bridges Jr, S., Zhernakova, Alexandra, Toes, Rene E. M., Tak, Paul P., Miceli-Richard, Corinne, Bang, So-Young, Lee, Hye-Soon, Martin, Javier, Gonzalez-Gay, Miguel A., Rodriguez-Rodriguez, Luis, Rantapää-Dahlqvist, Solbritt, Ärlestig, Lisbeth, Choi, Hyon K., Kamatani, Yoichiro, Galan, Pilar, Lathrop, Mark, Eyre, Steve, Bowes, John, Barton, Anne, de Vries, Niek, Moreland, Larry W., Criswell, Lindsey A., Karlson, Elizabeth W., Taniguchi, Atsuo, Yamada, Ryo, Kubo, Michiaki, Liu, Jun S., Bae, Sang-Cheol, Worthington, Jane, Padyukov, Leonid, Klareskog, Lars, Gregersen, Peter K., Raychaudhuri, Soumya, Stranger, Barbara E., De Jager, Philip L., Franke, Lude, Visscher, Peter M., Brown, Matthew A., Yamanaka, Hisashi, Mimori, Tsuneyo, Takahashi, Atsushi, Xu, Huji, Behrens, Timothy W., Siminovitch, Katherine A., Momohara, Shigeki, Matsuda, Fumihiko, Yamamoto, Kazuhiko, Plenge, Robert M.

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Trans-ethnic meta-analysis of white blood cell phenotypes von Keller, Margaux F, Reiner, Alexander P, Okada, Yukinori, van Rooij, Frank J A, Johnson, Andrew D, Chen, Ming-Huei, Smith, Albert V, Morris, Andrew P, Tanaka, Toshiko, Ferrucci, Luigi, Zonderman, Alan B, Lettre, Guillaume, Harris, Tamara, Garcia, Melissa, Bandinelli, Stefania, Qayyum, Rehan, Yanek, Lisa R, Becker, Diane M, Becker, Lewis C, Kooperberg, Charles, Keating, Brendan, Reis, Jared, Tang, Hua, Boerwinkle, Eric, Kamatani, Yoichiro, Matsuda, Koichi, Kamatani, Naoyuki, Nakamura, Yusuke, Kubo, Michiaki, Liu, Simin, Dehghan, Abbas, Felix, Janine F, Hofman, Albert, Uitterlinden, André G, van Duijn, Cornelia M, Franco, Oscar H, Longo, Dan L, Singleton, Andrew B, Psaty, Bruce M, Evans, Michelle K, Cupples, L Adrienne, Rotter, Jerome I, O'Donnell, Christopher J, Takahashi, Atsushi, Wilson, James G, Ganesh, Santhi K, Nalls, Mike A

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Genetic analysis of right heart structure and function in 40,000 people von Pirruccello, James P., Di Achille, Paolo, Nauffal, Victor, Nekoui, Mahan, Friedman, Samuel F., Klarqvist, Marcus D. R., Chaffin, Mark D., Weng, Lu-Chen, Cunningham, Jonathan W., Khurshid, Shaan, Roselli, Carolina, Lin, Honghuang, Koyama, Satoshi, Ito, Kaoru, Kamatani, Yoichiro, Komuro, Issei, Jurgens, Sean J., Benjamin, Emelia J., Batra, Puneet, Natarajan, Pradeep, Ng, Kenney, Hoffmann, Udo, Lubitz, Steven A., Ho, Jennifer E., Lindsay, Mark E., Philippakis, Anthony A., Ellinor, Patrick T.

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Leveraging supervised learning for functionally informed fine-mapping of cis-eQTLs identifies an additional 20,913 putative causal eQTLs von Wang, Qingbo S., Kelley, David R., Ulirsch, Jacob, Kanai, Masahiro, Sadhuka, Shuvom, Cui, Ran, Albors, Carlos, Cheng, Nathan, Okada, Yukinori, Aguet, Francois, Ardlie, Kristin G., MacArthur, Daniel G., Finucane, Hilary K.

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Pan-cancer and cross-population genome-wide association studies dissect shared genetic backgrounds underlying carcinogenesis von Sato, Go, Shirai, Yuya, Namba, Shinichi, Edahiro, Ryuya, Sonehara, Kyuto, Hata, Tsuyoshi, Uemura, Mamoru, Matsuda, Koichi, Doki, Yuichiro, Eguchi, Hidetoshi, Okada, Yukinori

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Identification of additional risk loci for stroke and small vessel disease: a meta-analysis of genome-wide association studies von Chauhan, Ganesh, Arnold, Corey R, Chu, Audrey Y, Reyahi, Azadeh, Bis, Joshua C, Havulinna, Aki S, Trompet, Stella, Manichaikul, Ani, Teumer, Alexander, Gustafsson, Stefan, Bartz, Traci M, Bellenguez, Céline, Vidal, Jean Sebastien, Kjartansson, Olafur, Satizabal, Claudia L, Xue, Flora, Liu, Yongmei, Bevan, Steve, Hopewell, Jemma C, Heckbert, Susan R, Rice, Kenneth, Smith, Nicholas L, Levi, Christopher, Sharma, Pankaj, Sudlow, Cathie LM, Cole, John W, Schmidt, Reinhold, Meschia, James, Thijs, Vincent, Melander, Olle, Grewal, Raji P, Sacco, Ralph L, Rundek, Tatjana, Rothwell, Peter M, Jern, Christina, Johnson, Julie A, Benavente, Oscar R, Lee, Jin-Moo, Wong, Quenna, Aparicio, Hugo J, Engelter, Stefan T, Kloss, Manja, Pezzini, Alessandro, Buring, Julie E, Ridker, Paul M, Berr, Claudine, Dartigues, Jean-François, Hamsten, Anders, Traylor, Matthew, Pedersen, Nancy L, Lannfelt, Lars, Morris, Andrew P, Jimenez-Conde, Jordi, Montaner, Joan, Slowik, Agnieszka, Woo, Daniel, Hofman, Albert, Koudstaal, Peter J, Portegies, Marileen L P, Uitterlinden, André G, Ford, Ian, Jukema, J Wouter, Stott, David J, Allen, Norrina B, Johnson, Andrew D, De Jager, Philip L, White, Charles C, Markus, Marcello Ricardo Paulista, Schminke, Ulf, Boncoraglio, Giorgio B, Clarke, Robert, Kamatani, Yoichiro, Dallongeville, Jean, Rotter, Jerome I, Nalls, Michael A, Griswold, Michael E, Knopman, David S, Windham, B Gwen, Beiser, Alexa, Vartiainen, Erkki, French, Curtis R, Pastinen, Tomi, Gudnason, Vilmundur, Kurth, Tobias, Harris, Tamara B, Rich, Stephen S, deStefano, Anita L, Rosand, Jonathan, Mosley, Thomas H, Ingelsson, Erik, van Duijn, Cornelia M, Tzourio, Christophe, Rexrode, Kathryn M, Lehmann, Ordan J, Launer, Lenore J, Carlsson, Peter, Chasman, Daniel I, Childs, Sarah J, Seshadri, Sudha, Debette, Stéphanie

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Genetic legacy of ancient hunter-gatherer Jomon in Japanese populations von Yamamoto, Kenichi, Namba, Shinichi, Sonehara, Kyuto, Suzuki, Ken, Sakaue, Saori, Cooke, Niall P., Higashiue, Shinichi, Kobayashi, Shuzo, Afuso, Hisaaki, Matsuura, Kosho, Mitsumoto, Yojiro, Fujita, Yasuhiko, Tokuda, Torao, Matsuda, Koichi, Gakuhari, Takashi, Yamauchi, Toshimasa, Kadowaki, Takashi, Nakagome, Shigeki, Okada, Yukinori

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Common and rare genetic variants predisposing females to unexplained recurrent pregnancy loss von Sonehara, Kyuto, Yano, Yoshitaka, Naito, Tatsuhiko, Goto, Shinobu, Yoshihara, Hiroyuki, Otani, Takahiro, Ozawa, Fumiko, Kitaori, Tamao, Matsuda, Koichi, Nishiyama, Takashi, Okada, Yukinori, Sugiura-Ogasawara, Mayumi

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ENIGMA CHEK2gether Project: A Comprehensive Study Identifies Functionally Impaired CHEK2 Germline Missense Variants Associated with Increased Breast Cancer Risk von Stolarova, Lenka, Kleiblova, Petra, Zemankova, Petra, Stastna, Barbora, Janatova, Marketa, Soukupova, Jana, Achatz, Maria Isabel, Ambrosone, Christine, Apostolou, Paraskevi, Arun, Banu K, Auer, Paul, Barnard, Mollie, Bertelsen, Birgitte, Blok, Marinus J, Boddicker, Nicholas, Brunet, Joan, Burnside, Elizabeth S, Calvello, Mariarosaria, Campbell, Ian, Chan, Sock Hoai, Chen, Fei, Chiang, Jian Bang, Coppa, Anna, Cortesi, Laura, Crujeiras-González, Ana, De Leeneer, Kim, De Putter, Robin, DePersia, Allison, Devereux, Lisa, Domchek, Susan, Efremidis, Anna, Engel, Christoph, Ernst, Corinna, Evans, D Gareth R, Feliubadaló, Lidia, Fostira, Florentia, Fuentes-Ríos, Olivia, Gómez-García, Encarna B, González, Sara, Haiman, Christopher, Hansen, Thomas van Overeem, Hauke, Jan, Hodge, James, Hu, Chunling, Huang, Hongyan, Ishak, Nur Diana Binte, Iwasaki, Yusuke, Konstantopoulou, Irene, Kraft, Peter, Lacey, James, Lázaro, Conxi, Li, Na, Lim, Weng Khong, Lindstrom, Sara, Lori, Adriana, Martinez, Elana, Martins, Alexandra, Matsuda, Koichi, Matullo, Giuseppe, McInerny, Simone, Michailidou, Kyriaki, Montagna, Marco, Monteiro, Alvaro N A, Mori, Luigi, Nathanson, Katherine, Neuhausen, Susan L, Nevanlinna, Heli, Olson, Janet E, Palmer, Julie, Pasini, Barbara, Patel, Alpa, Piane, Maria, Poppe, Bruce, Radice, Paolo, Renieri, Alessandra, Resta, Nicoletta, Richardson, Marcy E, Rosseel, Toon, Ruddy, Kathryn J, Santamariña, Marta, Dos Santos, Elizabeth Santana, Teras, Lauren, Toland, Amanda E, Trentham-Dietz, Amy, Vachon, Celine M, Volk, Alexander E, Weber-Lassalle, Nana, Weitzel, Jeffrey N, Wiesmuller, Lisa, Winham, Stacey, Yadav, Siddhartha, Yannoukakos, Drakoulis, Yao, Song, Zampiga, Valentina, Zethoven, Magnus, Zhang, Ze Wen, Zima, Tomas, Spurdle, Amanda B, Vega, Ana, Rossing, Maria

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Genetic overlap analysis of endometriosis and asthma identifies shared loci implicating sex hormones and thyroid signalling pathways von Adewuyi, E O, Mehta, D, Nyholt, D R

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Genetic analysis of endometriosis and depression identifies shared loci and implicates causal links with gastric mucosa abnormality von Adewuyi, Emmanuel O., Mehta, Divya, Sapkota, Yadav, Auta, Asa, Yoshihara, Kosuke, Nyegaard, Mette, Griffiths, Lyn R., Montgomery, Grant W., Chasman, Daniel I., Nyholt, Dale R.

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Convergent genetic and expression data implicate immunity in Alzheimer's disease von Jones, Lesley, Wang, Li-San, Choi, Seung-Hoan, Vedernikov, Alexey, Escott-Price, Valentina, Richards, Alexander, Naj, Adam C., Sims, Rebecca, Gerrish, Amy, Jun, Gyungah, Beecham, Gary W., Grenier-Boley, Benjamin, Smith, Albert V., Chouraki, Vincent, Thomas, Charlene, Zelenika, Diana, Vardarajan, Badri N., Kamatani, Yoichiro, Bihoreau, Marie-Thérèse, Reitz, Christiane, Pasquier, Florence, Hanon, Olivier, Buxbaum, Joseph D., Campion, Dominique, Crane, Paul K., Gudnason, Vilmundur, Cruchaga, Carlos, Craig, David, Berr, Claudine, Lopez, Oscar L., De Jager, Philip L., Deramecourt, Vincent, Evans, Denis, Tárraga, Lluís, Sleegers, Kristel, Gill, Michael, Emilsson, Valur, Keller, Lina, Barberger-Gateau, Pascale, McGuinness, Bernadette, Larson, Eric B., Myers, Amanda J., Dufouil, Carole, Todd, Stephen, Love, Seth, Kehoe, Pat, Rogaeva, Ekaterina, Gallacher, John, Tsuang, Debby W., Yu, Lei, Sorbi, Sandro, Fox, Nick, Hardy, John, Deniz Naranjo, Maria Candida, Clarke, Robert, Mancuso, Michelangelo, Mecocci, Patrizia, del Zompo, Maria, Maier, Wolfgang, Pilotto, Alberto, Bullido, Maria, Caffarra, Paolo, Gilbert, John R., Mayhaus, Manuel, Lannfelt, Lars, Pichler, Sabrina, Ingelsson, Martin, Beekly, Duane, Valladares, Otto, Coto, Eliecer, Hamilton-Nelson, Kara L., Owen, Michael J., Faber, Kelley M., O'Donovan, Michael C., Soininen, Hilkka, Mead, Simon, de Bruijn, Renee F.A.G., Rotter, Jerome I., Brice, Alexis, Morgan, Kevin, Foroud, Tatiana M., Hannequin, Didier, Powell, John F., Nalls, Michael A., Ritchie, Karen, Riemenschneider, Matthias, Boada, Mercè, Hiltunen, Mikko, Pastor, Pau, Mayeux, Richard, Graff, Caroline, Psaty, Bruce M., Haines, Jonathan L., Lathrop, Mark, Pericak-Vance, Margaret A., Launer, Lenore J., Farrer, Lindsay A., van Duijn, Cornelia M., Williams, Julie, Holmans, Peter A.

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Genome-wide association study of colorectal polyps identified highly overlapping polygenic architecture with colorectal cancer von Hikino, Keiko, Koido, Masaru, Otomo, Nao, Tomizuka, Kohei, Ikegawa, Shiro, Matsuda, Koichi, Momozawa, Yukihide, Mushiroda, Taisei, Terao, Chikashi

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Model-based assessment of replicability for genome-wide association meta-analysis von McGuire, Daniel, Jiang, Yu, Liu, Mengzhen, Weissenkampen, J. Dylan, Eckert, Scott, Yang, Lina, Chen, Fang, Berg, Arthur, Vrieze, Scott, Jiang, Bibo, Li, Qunhua, Liu, Dajiang J.

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The human AIRE gene at chromosome 21q22 is a genetic determinant for the predisposition to rheumatoid arthritis in Japanese population von TERAO, Chikashi, YAMADA, Ryo, LATHROP, Mark, MIMORI, Tsuneyo, MATSUDA, Fumihiko, OHMUR, Koichiro, TAKAHASHI, Meiko, KAWAGUCHI, Takahisa, KOCHI, Yuta, OKADA, Yukinori, NAKAMURA, Yusuke, YAMAMOTO, Kazuhiko, MELCHERS, Inga

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Multi-ancestry meta-analysis of host genetic susceptibility to tuberculosis identifies shared genetic architecture von Schurz, Haiko, Naranbhai, Vivek, Yates, Tom A, Gilchrist, James J, Parks, Tom, Dodd, Peter J, Möller, Marlo, Hoal, Eileen G, Morris, Andrew P, Hill, Adrian V S

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