Discovery and systematic characterization of risk variants and genes for coronary artery disease in over a million participants von Aragam, Krishna G., Jiang, Tao, Goel, Anuj, Kanoni, Stavroula, Wolford, Brooke N., Atri, Deepak S., Weeks, Elle M., Wang, Minxian, Hindy, George, Zhou, Wei, Grace, Christopher, Roselli, Carolina, Marston, Nicholas A., Kamanu, Frederick K., Surakka, Ida, Venegas, Loreto Muñoz, Sherliker, Paul, Koyama, Satoshi, Ishigaki, Kazuyoshi, Åsvold, Bjørn O., Brown, Michael R., Brumpton, Ben, de Vries, Paul S., Giannakopoulou, Olga, Giardoglou, Panagiota, Gudbjartsson, Daniel F., Güldener, Ulrich, Haider, Syed M. Ijlal, Helgadottir, Anna, Ibrahim, Maysson, Kastrati, Adnan, Kessler, Thorsten, Kyriakou, Theodosios, Konopka, Tomasz, Li, Ling, Ma, Lijiang, Meitinger, Thomas, Mucha, Sören, Munz, Matthias, Murgia, Federico, Nielsen, Jonas B., Nöthen, Markus M., Pang, Shichao, Reinberger, Tobias, Schnitzler, Gavin, Smedley, Damian, Thorleifsson, Gudmar, von Scheidt, Moritz, Ulirsch, Jacob C., Arnar, David O., Burtt, Noël P., Costanzo, Maria C., Flannick, Jason, Ito, Kaoru, Jang, Dong-Keun, Kamatani, Yoichiro, Khera, Amit V., Komuro, Issei, Kullo, Iftikhar J., Lotta, Luca A., Nelson, Christopher P., Roberts, Robert, Thorgeirsson, Gudmundur, Thorsteinsdottir, Unnur, Webb, Thomas R., Baras, Aris, Björkegren, Johan L. M., Boerwinkle, Eric, Dedoussis, George, Holm, Hilma, Hveem, Kristian, Melander, Olle, Morrison, Alanna C., Orho-Melander, Marju, Rallidis, Loukianos S., Ruusalepp, Arno, Sabatine, Marc S., Stefansson, Kari, Zalloua, Pierre, Ellinor, Patrick T., Farrall, Martin, Danesh, John, Ruff, Christian T., Finucane, Hilary K., Hopewell, Jemma C., Clarke, Robert, Gupta, Rajat M., Erdmann, Jeanette, Samani, Nilesh J., Schunkert, Heribert, Watkins, Hugh, Willer, Cristen J., Deloukas, Panos, Kathiresan, Sekar, Butterworth, Adam S.

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Predicting Benefit From Evolocumab Therapy in Patients With Atherosclerotic Disease Using a Genetic Risk Score: Results From the FOURIER Trial von Marston, Nicholas A., Kamanu, Frederick K., Nordio, Francesco, Gurmu, Yared, Roselli, Carolina, Sever, Peter S., Pedersen, Terje R., Keech, Anthony C., Wang, Huei, Lira Pineda, Armando, Giugliano, Robert P., Lubitz, Steven A., Ellinor, Patrick T., Sabatine, Marc S., Ruff, Christian T.

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Privacy-aware multi-institutional time-to-event studies von Späth, Julian, Matschinske, Julian, Kamanu, Frederick K, Murphy, Sabina A, Zolotareva, Olga, Bakhtiari, Mohammad, Antman, Elliott M, Loscalzo, Joseph, Brauneck, Alissa, Schmalhorst, Louisa, Buchholtz, Gabriele, Baumbach, Jan

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A polygenic risk score predicts atrial fibrillation in cardiovascular disease von Marston, Nicholas A, Garfinkel, Amanda C, Kamanu, Frederick K, Melloni, Giorgio M, Roselli, Carolina, Jarolim, Petr, Berg, David D, Bhatt, Deepak L, Bonaca, Marc P, Cannon, Christopher P, Giugliano, Robert P, O'Donoghue, Michelle L, Raz, Itamar, Scirica, Benjamin M, Braunwald, Eugene, Morrow, David A, Ellinor, Patrick T, Lubitz, Steven A, Sabatine, Marc S, Ruff, Christian T

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Per-Particle Cardiovascular Risk of Lipoprotein(a) vs Non-Lp(a) Apolipoprotein B-Containing Lipoproteins von Marston, Nicholas A., Melloni, Giorgio E.M., Murphy, Sabina A., Morze, Jakub, Kamanu, Frederick K., Ellinor, Patrick T., Ruff, Christian T., Sabatine, Marc S.

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Type 2 diabetes genetic risk and incident diabetes across diabetes risk enhancers von Moura, Filipe A., Kamanu, Frederick K., Wiviott, Stephen D., Giugliano, Robert P., Udler, Miriam S., Florez, Jose C., Ellinor, Patrick T., Sabatine, Marc S., Ruff, Christian T., Marston, Nicholas A.

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Identification of Novel Loci Associated With Hip Shape: A Meta‐Analysis of Genomewide Association Studies von Baird, Denis A, Evans, Daniel S, Kamanu, Frederick K, Gregory, Jennifer S, Saunders, Fiona R, Giuraniuc, Claudiu V, Barr, Rebecca J, Aspden, Richard M, Jenkins, Deborah, Kiel, Douglas P, Orwoll, Eric S, Cummings, Steven R, Lane, Nancy E, Mullin, Benjamin H, Williams, Frances MK, Richards, J Brent, Wilson, Scott G, Spector, Tim D, Faber, Benjamin G, Lawlor, Deborah A, Grundberg, Elin, Ohlsson, Claes, Pettersson‐Kymmer, Ulrika, Capellini, Terence D, Richard, Daniel, Beck, Thomas J, Evans, David M, Paternoster, Lavinia, Karasik, David, Tobias, Jonathan H

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Clinical Application of a Novel Genetic Risk Score for Ischemic Stroke in Patients With Cardiometabolic Disease von Marston, Nicholas A., Patel, Parth N., Kamanu, Frederick K., Nordio, Francesco, Melloni, Giorgio M., Roselli, Carolina, Gurmu, Yared, Weng, Lu-Chen, Bonaca, Marc P., Giugliano, Robert P., Scirica, Benjamin M., O’Donoghue, Michelle L., Cannon, Christopher P., Anderson, Christopher D., Bhatt, Deepak L., Gabriel Steg, Philippe, Cohen, Marc, Storey, Robert F., Sever, Peter, Keech, Anthony C., Raz, Itamar, Mosenzon, Ofri, Antman, Elliott M., Braunwald, Eugene, Ellinor, Patrick T., Lubitz, Steven A., Sabatine, Marc S., Ruff, Christian T.

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Publisher Correction: Stroke genetics informs drug discovery and risk prediction across ancestries von Jürgenson, Tuuli, Namba, Shinichi, Posner, Daniel C., Kamanu, Frederick K., Koido, Masaru, He, Yunye, Caro, Ilana, Krebs, Kristi, Liaw, Yi-Ching, Parodi, Livia, Bae, Hee-Joon, Chong, Michael R., Tomppo, Liisa, Akinyemi, Rufus, Roshchupkin, Gennady V., Habib, Naomi, Jee, Yon Ho, Thomassen, Jesper Qvist, Abedi, Vida, Cárcel-Márquez, Jara, Nygaard, Marianne, Yonova-Doing, Ekaterina, Knol, Maria J., Lewis, Adam J., Judy, Renae L., Amouyel, Philippe, Bakker, Mark K., Bennett, David A., Bis, Joshua C., Bordes, Constance, Børte, Sigrid, Cain, Anael, Ridker, Paul M., Cho, Kelly, Chen, Zhengming, Cruchaga, Carlos, Cole, John W., de Cid, Rafael, Ferreira, Leslie E., He, Jing, Jeon, Christina E., Jern, Christina, Kamouchi, Masahiro, Keene, Keith L., Konuma, Takahiro, Kumar, Amit, Launer, Lenore J., Lee, Keon-Joo, Li, Jiang, Li, Liming, Manichaikul, Ani, Markus, Hugh S., Meitinger, Thomas, Mitchell, Braxton D., Morisaki, Takayuki, O’Donnell, Martin J., Onland-Moret, N. Charlotte, Ovbiagele, Bruce, Peters, Annette, Rosand, Jonathan, Sabatine, Marc S., Sacco, Ralph L., Saleheen, Danish, Schmidt, Carsten O., Smith, Nicholas L., Sloane, Kelly L., Sutoh, Yoichi, Tiwari, Hemant K., Wennberg, Patrik, Wilson, Peter W. F., Yang, Qiong, Yoon, Kyungheon, Gieger, Christian, Ninomiya, Toshiharu, Grabe, Hans J., Jukema, J. Wouter, Kim, Young Jin, Chen, Pei-Hsin, Mayerhofer, Ernst, Ikram, Mohammad A., Worrall, Bradford B., Lathrop, G. Mark, Riaz, Moeen, Simonsick, Eleanor M., Kõrv, Janika, Zand, Ramin, Prasad, Kameshwar, Frikke-Schmidt, Ruth, Liman, Thomas, Ruigrok, Ynte M., Bastarache, Lisa, Damrauer, Scott M., Rotter, Jerome I., Niiranen, Teemu J., Walters, Robin G., Owolabi, Mayowa O., Huffman, Jennifer E., Kamatani, Yoichiro, Dichgans, Martin, Debette, Stephanie

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Incremental Elevations in TNFα and IL6 in the Human Colon and Procancerous Changes in the Mucosal Transcriptome Accompany Adiposity von Pfalzer, Anna C, Leung, Keith, Crott, Jimmy W, Kim, Susan J, Tai, Albert K, Parnell, Laurence D, Kamanu, Frederick K, Liu, Zhenhua, Rogers, Gail, Shea, M Kyla, Garcia, Paloma E, Mason, Joel B

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Interactions between the colonic transcriptome, metabolome, and microbiome in mouse models of obesity-induced intestinal cancer von Pfalzer, Anna C, Kamanu, Frederick K, Parnell, Laurence D, Tai, Albert K, Liu, Zhenhua, Mason, Joel B, Crott, Jimmy W

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Genetic Risk Score to Identify Risk of Venous Thromboembolism in Patients With Cardiometabolic Disease von Marston, Nicholas A., Melloni, Giorgio E.M., Gurmu, Yared, Bonaca, Marc P., Kamanu, Frederick K., Roselli, Carolina, Lee, Christina, Cavallari, Ilaria, Giugliano, Robert P., Scirica, Benjamin M., Bhatt, Deepak L., Steg, Philippe Gabriel, Cohen, Marc, Storey, Robert F., Keech, Anthony C., Raz, Itamar, Mosenzon, Ofri, Braunwald, Eugene, Lubitz, Steven A., Ellinor, Patrick T., Sabatine, Marc S., Ruff, Christian T.

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Genetic drivers of heterogeneity in type 2 diabetes pathophysiology von Southam, Lorraine, Yin, Xianyong, Melloni, Giorgio E. M., Rayner, Nigel W., Bocher, Ozvan, Namba, Shinichi, Lee, Simon S. K., Petty, Lauren E., Schroeder, Philip, Kals, Mart, Zhang, Weihua, Graff, Mariaelisa, Lamri, Amel, Parra, Esteban J., Bielak, Lawrence F., Hai, Yang, Sofer, Tamar, Nousome, Darryl, Sun, Meng, Noordam, Raymond, Lim, Victor J. Y., Yanek, Lisa R., An, Ping, Tan, Jingyi, Canouil, Mickaël, Chee, Miao-Li, Chen, Shyh-Huei, Chen, Yuan-Tsong, Dimitrov, Latchezar, Doumatey, Ayo P., Du, Shufa, Eckardt, Kai-Uwe, Gerstein, Hertzel C., Han, Sohee, Herder, Christian, Howard, Annie-Green, Hsueh, Willa, Ichihara, Sahoko, Ikram, Mohammad Arfan, Jang, Hye-Mi, Jonas, Jost B., Kandeel, Fouad R., Kaur, Varinderpal, Lange, Leslie A., Lee, Myung-Shik, Leong, Aaron, Liu, Ching-Ti, Louie, Tin, Luo, Xi, Maeda, Shiro, Mansuri, Sohail Rafik, Nalls, Michael A., Nayak, Uma, Okada, Yukinori, Patil, Snehal, Prasad, Gauri, Roden, Michael, Rohde, Rebecca, Sandow, Kevin, Sankareswaran, Alagu, So, Wing Yee, Stilp, Adrienne M., Taylor, Kent D., Thorand, Barbara, Valladares-Salgado, Adan, Wheeler, Eleanor, Raffel, Leslie J., Igase, Michiya, Province, Michael A., Rotimi, Charles N., Peyser, Patricia A., Pankow, James S., Wilson, James G., Sheu, Wayne H. H., Mook-Kanamori, Dennis O., Collins, Francis S., Paré, Guillaume, Shu, Xiao-Ou, Dupuis, Josee, Kato, Norihiro, Laakso, Markku, Wareham, Nicholas J., Kim, Bong-Jo, Stefansson, Kari, Goodarzi, Mark O., Mohlke, Karen L., Florez, Jose C., Zöllner, Sebastian, Mägi, Reedik, van Heel, David A., Finer, Sarah, Ng, Maggie C. Y., Sim, Xueling, Below, Jennifer E., Chang, Kyong-Mi, Meigs, James B., Mahajan, Anubha, Vujkovic, Marijana, Voight, Benjamin F., Morris, Andrew P.

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Abstract 9399: A Targeted Proteomic Approach Identifies Novel Biomarkers Associated With Risk of Myocardial Infarction in Post-Menopausal Women von Patel, Siddharth M, Morrow, David A, Tang, Minao, Kamanu, Frederick K, Im, KyungAh, Sabatine, Marc S, Odonoghue, Michelle L

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Abstract 9393: A Genetic Risk Score to Predict Peripheral Artery Disease and Acute Limb Ischemia in Patients With Cardiometabolic Disease von Patel, Siddharth M, Marston, Nicholas A, Melloni, Giorgio E, Kamanu, Frederick K, Roselli, Carolina, Antman, Elliott M, Bhatt, Deepak L, Braunwald, Eugene, Cannon, Christopher P, Odonoghue, Michelle L, Giugliano, Robert P, Mosenzon, Ofri, Scirica, Benjamin M, Lubitz, Steven A, Ellinor, Patrick T, Bonaca, Marc P, Sabatine, Marc S, Ruff, Christian T

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Abstract 9110: Use of a Genetic Risk Score to Predict Atrial Fibrillation in Patients With Cardiovascular Disease von Garfinkel, Amanda C, Marston, Nicholas A, Kamanu, Frederick K, Melloni, Giorgio M, Roselli, Carolina, Bhatt, Deepak L, Bonaca, Marc P, Cannon, Christopher P, Giugliano, Robert P, Odonoghue, Michelle L, RAZ, Itamar, Scirica, Benjamin M, Braunwald, Eugene, Ellinor, Patrick T, Lubitz, Steven A, Sabatine, Marc S, Ruff, Christian T

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Stroke genetics informs drug discovery and risk prediction across ancestries von Mishra, Aniket, Malik, Rainer, Hachiya, Tsuyoshi, Jurgenson, Tuuli, Namba, Shinichi, Posner, Daniel C., Kamanu, Frederick K., Koido, Masaru, Le Grand, Quentin, Shi, Mingyang, He, Yunye, Georgakis, Marios K., Caro, Ilana, Krebs, Kristi, Liaw, Yi-Ching, Vaura, Felix C., Lin, Kuang, Winsvold, Bendik Slagsvold, Srinivasasainagendra, Vinodh, Parodi, Livia, Bae, Hee-Joon, Chauhan, Ganesh, Chong, Michael R, Tomppo, Liisa, Roshchupkin, Gennady V., Habib, Naomi, Jee, Yon Ho, Thomassen, Jesper Qvist, Abedi, Vida, Carcel-Marquez, Jara, Nygaard, Marianne, Leonard, Hampton L., Yang, Chaojie, Yonova-Doing, Ekaterina, Knol, Maria J., Lewis, Adam J.., Judy, Renae L, Ago, Tetsuro, Amouyel, Philippe, Armstrong, Nicole D., Bakker, Mark K., Bartz, Traci M., Bennett, David A., Bis, Joshua C., Bordes, Constance, Borte, Sigrid, Cain, Anael, Ridker, Paul M., Cho, Kelly, Chen, Zhengming, Cruchaga, Carlos, Cole, John W., de Jager, Phil L., de Cid, Rafael, Endres, Matthias, Ferreira, Leslie E., Geerlings, Mirjam I., Gasca, Natalie C., Gudnason, Vilmundur, Hata, Jun, He, Jing, Heath, Alicia K., Ho, Yuk-Lam, Havulinna, Aki S., Hopewell, Jemma .C, Hyacinth, Hyacinth I., Inouye, Michael, Jacob, Mina A., Jeon, Christina E., Jern, Christina, Kamouchi, Masahiro, Keene, Keith L., Kitazono, Takanari, Kittner, Steven J., Konuma, Takahiro, Kumar, Amit, Lacaze, Paul, Launer, Lenore J., Lee, Keon-Joo, Lepik, Kaido, Li, Jiang, Li, Liming, Manichaikul, Ani, Markus, Hugh S., Marston, Nicholas A., Meitinger, Thomas, Mitchell, Braxton D., Montellano, Felipe A., Morisaki, Takayuki, Mosley, Thomas H., Nalls, Mike A., Nordestgaard, Borge G., O'Donnell, Martin J., Okada, Yukinori, Onland-Moret, N. Charlotte, Ovbiagele, Bruce, Peters, Annette, Psaty, Bruce M, Rich, Stephen S.., Rosand, Jonathan

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Abstract 13702: A Novel Genetic Risk Score Predicts Ischemic Stroke in Patients With Cardiometabolic Disease von Patel, Parth N, Marston, Nicholas A, Kamanu, Frederick K, Weng, Lu Chen, Bonaca, Marc P, Giugliano, Robert P, Scirica, Benjamin M, O'Donoghue, Michelle L, Cannon, Christopher P, ANDERSON, Christopher D, Bhatt, Deepak L, Steg, Philippe G, Cohen, Marc, Storey, Robert F, Sever, Peter S, Keech, Anthony C, RAZ, Itamar, Mosenzon, ofri, Braunwald, Eugene, Ellinor, Patrick T, Lubitz, Steven A, Sabatine, Marc S, Ruff, Christian T

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Clinical Application of a Novel Genetic Risk Score for Ischemic Stroke in Patients with Cardiometabolic Disease von Marston, Nicholas A., Patel, Parth N., Kamanu, Frederick K., Nordio, Francesco, Melloni, Giorgio M, Roselli, Carolina, Gurmu, Yared, Weng, Lu-Chen, Bonaca, Marc P., Giugliano, Robert P., Scirica, Benjamin M., O’Donoghue, Michelle L., Cannon, Christopher P., Anderson, Christopher D., Bhatt, Deepak L., Gabriel Steg, Philippe, Cohen, Marc, Storey, Robert F., Sever, Peter, Keech, Anthony C., Raz, Itamar, Mosenzon, Ofri, Antman, Elliott M., Braunwald, Eugene, Ellinor, Patrick T., Lubitz, Steven A., Sabatine, Marc S., Ruff, Christian T.

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Privacy-aware multi-institutional time-to-event studies von Julian Späth, Julian Matschinske, Frederick K Kamanu, Sabina A Murphy, Olga Zolotareva, Mohammad Bakhtiari, Elliott M Antman, Joseph Loscalzo, Alissa Brauneck, Louisa Schmalhorst, Gabriele Buchholtz, Jan Baumbach

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