Renin inhibitors containing isosteric replacements of the amide bond connecting the P3 and P2 sites von Kaltenbronn, James S, Hudspeth, J. P, Lunney, E. A, Michniewicz, B. M, Nicolaides, E. D, Repine, J. T, Roark, W. H, Stier, M. A, Tinney, F. J

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C-Terminal Modifications of Histidyl-N-benzylglycinamides To Give Improved Inhibition of Ras Farnesyltransferase, Cellular Activity, and Anticancer Activity in Mice von McNamara, Dennis J, Dobrusin, Ellen, Leonard, Daniele M, Shuler, Kevon R, Kaltenbronn, James S, Quin, John, Bur, Scott, Thomas, Charles E, Doherty, Annette M, Scholten, Jeffrey D, Zimmerman, Karen K, Gibbs, Barbara S, Gowan, Richard C, Latash, Michael P, Leopold, Wilbur R, Przybranowski, Sally A, Sebolt-Leopold, Judith S

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Design and synthesis of potent, selective, and orally active fluorine-containing renin inhibitors von Doherty, Annette M, Sircar, Ila, Kornberg, Brian E, Quin, John, Winters, R. Thomas, Kaltenbronn, James S, Taylor, Michael D, Batley, Brian L, Rapundalo, Stephen R

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Design and Synthesis of Renin Inhibitors: Incorporation of Transition-State Isostere Side Chains That Span from the S1 to the S3 Binding Pockets and Examination of P3-Modified Reni... von Shahripour, Aurash, Kaltenbronn, James S, Lunney, Elizabeth A, Steinbaugh, Bruce A, Hamby, James M, Hamilton, Harriet W, Sawyer, Tomi K, Humblet, Christine, Doherty, Annette M

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Analyses of ligand binding in five endothiapepsin crystal complexes and their use in the design and evaluation of novel renin inhibitors von Lunney, Elizabeth A, Hamilton, Harriet W, Hodges, John C, Kaltenbronn, James S, Repine, Joseph T, Badasso, Mohammed, Cooper, Jon B, Dealwis, Chris, Wallace, Bonnie A

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Renin inhibitors containing .alpha.-heteroatom amino acids as P2 residues von Repine, Joseph T, Kaltenbronn, James S, Doherty, Annette M, Hamby, James M, Himmelsbach, Richard J, Kornberg, Brian E, Taylor, Michael D, Lunney, ELizabeth A, Humblet, Christine

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New inhibitors of human renin that contain novel replacements at the P2 site von Doherty, Annette M, Kaltenbronn, James S, Hudspeth, James P, Repine, Joseph T, Roark, William H, Sircar, Ila, Tinney, Frank J, Connolly, Cleo J, Hodges, John C

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Renin inhibitors containing esters at the P2-position. Oral activity in a derivative of methyl aminomalonate von Repine, Joseph T, Himmelsbach, Richard J, Hodges, John C, Kaltenbronn, James S, Sircar, Ila, Skeean, Richard W, Brennan, Sean T, Hurley, Timothy R, Lunney, Elizabeth

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Structure-activity relationships of the potent combined endothelinA/endothelinB receptor antagonist Ac-DDip16-Leu-Asp-Ile-Ile-Trp21 (PD 142893): development of endothelinB receptor... von Cody, Wayne L, He, John X, DePue, Patricia L, Waite, Lisa A, Leonard, Daniele M, Sefler, Andrea M, Kaltenbronn, James S, Haleen, Stephen J, Walker, Donnelle M, Flynn, Michael A, Welch, Kathleen, Reynolds, Elwood E, Doherty, Annette M

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4- and 5-Aryl-1-naphthaleneacetic acids as antiinflammatory agents von Kaltenbronn, James S

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Antiinflammatory activity of isomeric phenylnaphthaleneacetic acids von Kaltenbronn, James S

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Synthesis of a Bromine-Rich Marine Antibiotic von Hanessian, Stephen, Kaltenbronn, James S

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CI-867, A NEW BROAD-SPECTRUM SEMISYNTHETIC PENICILLIN von KALTENBRONN, JAMES S., HASKELL, THEODORE H., DOUB, LEONARD, KNOBLE, JAMES, DEJOHN, DANA, KROLLS, ULDIS, JENESEL, NICKOLAS, HUANG, GIN-GUEI, HEIFETZ, CARL L., FISHER, M. W.

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4-(and 5-)(2-Thienyl)-1-naphthaleneacetic acids as antiinflammatory agents von Kaltenbronn, James S, Rhee, Tae O

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SEMISYNTHETIC PENICILLINS AND CEPHALOSPORINS CONTAINING THE SUBSTITUTED 6-VINYL-1, 2-DIHYDRO-2-OXO- AND 1, 4-DIHYDRO-4-OXO-3-PYRIDINECARBOXYLIC ACID SIDE CHAINS: SYNTHESIS AND STRU... von DEJOHN, DANA, DOMAGALA, JOHN M., HASKELL, THEODORE H., HEIFETZ, CARL L., HUANG, GIN-GUEI, KALTENBRONN, JAMES S., KROLLS, ULDIS

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Evaluation of Physicochemical Parameters Important to the Oral Bioavailability of Peptide-like Compounds: Implications for the Synthesis of Renin Inhibitors von Hamilton, Harriet W, Steinbaugh, Bruce A, Stewart, Barbra H, Chan, O. Helen, Schmid, Heidi L, Schroeder, Richard, Ryan, Michael J, Keiser, Joan, Taylor, Michael D

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5-Aryl-2-furanacetic acids von Kaltenbronn, James S, Rhee, Tae O

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Thienyl-1-naphthalene acetic acids and related compounds von KALTENBRONN JAMES S

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SYNTHESIS OF [S-(R,R)] - ETHYL α-[(1-CARBOXYETHYL) AMINO]-BENEZENEBUTANOATE, AN IMPORTANT INTERMEDIATE IN THE SYNTHESIS OF ANGIOTENSIN CONVERTING ENZYME INHIBITORS von Kaltenbronn, James S., Dejohn, Dana, Krolls, Uldis

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Benzopyranone and quinolone inhibitors of ras farnesyl transferase von LEONARD, DANIELE MARIE, REPINE, JOSEPH THOMAS, KALTENBRONN, JAMES STANLEY

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