A Large Scale Huntingtin Protein Interaction Network Implicates Rho GTPase Signaling Pathways in Huntington Disease von Tourette, Cendrine, Li, Biao, Bell, Russell, O'Hare, Shannon, Kaltenbach, Linda S., Mooney, Sean D., Hughes, Robert E.

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SIRT2- and NRF2-Targeting Thiazole-Containing Compound with Therapeutic Activity in Huntington's Disease Models von Quinti, Luisa, Casale, Malcolm, Moniot, Sébastien, Pais, Teresa F., Van Kanegan, Michael J., Kaltenbach, Linda S., Pallos, Judit, Lim, Ryan G., Naidu, Sharadha Dayalan, Runne, Heike, Meisel, Lisa, Rauf, Nazifa Abdul, Leyfer, Dmitriy, Maxwell, Michele M., Saiah, Eddine, Landers, John E., Luthi-Carter, Ruth, Abagyan, Ruben, Dinkova-Kostova, Albena T., Steegborn, Clemens, Marsh, J. Lawrence, Lo, Donald C., Thompson, Leslie M., Kazantsev, Aleksey G.

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Huntingtin interacting proteins are genetic modifiers of neurodegeneration von Kaltenbach, Linda S, Romero, Eliana, Becklin, Robert R, Chettier, Rakesh, Bell, Russell, Phansalkar, Amit, Strand, Andrew, Torcassi, Cameron, Savage, Justin, Hurlburt, Anthony, Cha, Guang-Ho, Ukani, Lubna, Chepanoske, Cindy Lou, Zhen, Yuejun, Sahasrabudhe, Sudhir, Olson, James, Kurschner, Cornelia, Ellerby, Lisa M, Peltier, John M, Botas, Juan, Hughes, Robert E

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Activated microglia proliferate at neurites of mutant huntingtin-expressing neurons von Kraft, Andrew D, Kaltenbach, Linda S, Lo, Donald C, Harry, G. Jean

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Dual activities of the anti-cancer drug candidate PBI-05204 provide neuroprotection in brain slice models for neurodegenerative diseases and stroke von Van Kanegan, Michael J., Dunn, Denise E., Kaltenbach, Linda S., Shah, Bijal, He, Dong Ning, McCoy, Daniel D., Yang, Peiying, Peng, Jiangnan, Shen, Li, Du, Lin, Cichewicz, Robert H., Newman, Robert A., Lo, Donald C.

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Perturbation with intrabodies reveals that calpain cleavage is required for degradation of huntingtin exon 1 von Southwell, Amber L, Bugg, Charles W, Kaltenbach, Linda S, Dunn, Denise, Butland, Stefanie, Weiss, Andreas, Paganetti, Paolo, Lo, Donald C, Patterson, Paul H

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Identification of anti-inflammatory targets for Huntington's disease using a brain slice-based screening assay von Reinhart, Peter H, Kaltenbach, Linda S, Essrich, Christian, Dunn, Denise E, Eudailey, Joshua A, DeMarco, C. Todd, Turmel, Gregory J, Whaley, Jennifer C, Wood, Andrew, Cho, Seongeun, Lo, Donald C

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IKK phosphorylates Huntingtin and targets it for degradation by the proteasome and lysosome von Thompson, Leslie Michels, Aiken, Charity T, Kaltenbach, Linda S, Agrawal, Namita, Illes, Katalin, Khoshnan, Ali, Martinez-Vincente, Marta, Arrasate, Montserrat, O'Rourke, Jacqueline Gire, Khashwji, Hasan, Lukacsovich, Tamas, Zhu, Ya-Zhen, Lau, Alice L, Massey, Ashish, Hayden, Michael R, Zeitlin, Scott O, Finkbeiner, Steven, Green, Kim N, LaFerla, Frank M, Bates, Gillian, Huang, Lan, Patterson, Paul H, Lo, Donald C, Cuervo, Ana Maria, Marsh, J. Lawrence, Steffan, Joan S

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Suppressing aberrant GluN3A expression rescues synaptic and behavioral impairments in Huntington's disease models von Marco, Sonia, Giralt, Albert, Petrovic, Milos M, Pouladi, Mahmoud A, Martínez-Turrillas, Rebeca, Martínez-Hernández, José, Kaltenbach, Linda S, Torres-Peraza, Jesús, Graham, Rona K, Watanabe, Masahiko, Luján, Rafael, Nakanishi, Nobuki, Lipton, Stuart A, Lo, Donald C, Hayden, Michael R, Alberch, Jordi, Wesseling, John F, Pérez-Otaño, Isabel

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Experimental Models for Identifying Modifiers of Polyglutamine-Induced Aggregation and Neurodegeneration von Calamini, Barbara, Lo, Donald C., Kaltenbach, Linda S.

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Composite Primary Neuronal High-Content Screening Assay for Huntington’s Disease Incorporating Non-Cell-Autonomous Interactions von Kaltenbach, Linda S., Bolton, M. Mclean, Shah, Bijal, Kanju, Patrick M., Lewis, Gwendolyn M., Turmel, Gregory J., Whaley, Jennifer C., Trask, O. Joseph, Lo, Donald C.

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Contribution of the amino and carboxyl termini for PHA‐4/FoxA function in Caenorhabditis elegans von Kaltenbach, Linda S., Updike, Dustin L., Mango, Susan E.

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Methylation patterns in pap regulatory DNA control pyelonephritis-associated pili phase variation in E. coli von Braaten, Bruce A., Nou, Xiangwu, Kaltenbach, Linda S., Low, David A.

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KEAP1-modifying small molecule reveals muted NRF2 signaling responses in neural stem cells from Huntington’s disease patients von Quinti, Luisa, Naidu, Sharadha Dayalan, Träger, Ulrike, Chen, Xiqun, Kegel-Gleason, Kimberly, Llères, David, Connolly, Colúm, Chopra, Vanita, Low, Cho, Moniot, Sébastien, Sapp, Ellen, Tousley, Adelaide R., Vodicka, Petr, Van Kanegan, Michael J., Kaltenbach, Linda S., Crawford, Lisa A., Fuszard, Matthew, Higgins, Maureen, Miller, James R. C., Farmer, Ruth E., Potluri, Vijay, Samajdar, Susanta, Meisel, Lisa, Zhang, Ningzhe, Snyder, Andrew, Stein, Ross, Hersch, Steven M., Ellerby, Lisa M., Weerapana, Eranthie, Schwarzschild, Michael A., Steegborn, Clemens, Leavitt, Blair R., Degterev, Alexei, Tabrizi, Sarah J., Lo, Donald C., DiFiglia, Marian, Thompson, Leslie M., Dinkova-Kostova, Albena T., Kazantsev, Aleksey G.

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TR-FRET-Based Duplex Immunoassay Reveals an Inverse Correlation of Soluble and Aggregated Mutant huntingtin in Huntington's Disease von Baldo, Barbara, Paganetti, Paolo, Grueninger, Stephan, Marcellin, David, Kaltenbach, Linda S., Lo, Donald C., Semmelroth, Martin, Zivanovic, Andjelija, Abramowski, Dorothée, Smith, Donna, Lotz, Gregor P., Bates, Gillian P., Weiss, Andreas

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L20 Olesoxime targets calpain overactivation in models of huntington’s disease von Weber, Jonasz J, Ortiz-Rios, Midea M, Klumpp, Lukas, Kaltenbach, Linda S, Lo, Don C, Huber, Stephan M, Riess, Olaf, Clemens, Laura E, Nguyen, Huu P

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KEAP1-modifying small molecule reveals muted NRF2 signaling responses in neural stem cells from Huntington's disease patients von Quinti, Luisa, Dayalan Naidu, Sharadha, Träger, Ulrike, Chen, Xiqun, Kegel-Gleason, Kimberly, Llères, David, Connolly, Colúm, Chopra, Vanita, Low, Cho, Moniot, Sébastien, Sapp, Ellen, Tousley, Adelaide R, Vodicka, Petr, Van Kanegan, Michael J, Kaltenbach, Linda S, Crawford, Lisa A, Fuszard, Matthew, Higgins, Maureen, Miller, James RC, Farmer, Ruth E, Potluri, Vijay, Samajdar, Susanta, Meisel, Lisa, Zhang, Ningzhe, Snyder, Andrew, Stein, Ross, Hersch, Steven M, Ellerby, Lisa M, Weerapana, Eranthie, Schwarzschild, Michael A, Steegborn, Clemens, Leavitt, Blair R, Degterev, Alexei, Tabrizi, Sarah J, Lo, Donald C, DiFiglia, Marian, Thompson, Leslie M, Dinkova-Kostova, Albena T, Kazantsev, Aleksey G

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Identification and Evaluation of Small Molecule Pan-Caspase Inhibitors in Huntington's Disease Models von Leyva, Melissa J., DeGiacomo, Francesco, Kaltenbach, Linda S., Holcomb, Jennifer, Zhang, Ningzhe, Gafni, Juliette, Park, Hyunsun, Lo, Donald C., Salvesen, Guy S., Ellerby, Lisa M., Ellman, Jonathan A.

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Suppressing aberrant GluN3A expression rescues synaptic and behavioral impairments in Huntington's disease models von Marco, Sonia, Giralt Torroella, Albert, Petrovic, Milos, Pouladi, Mahmoud A, Martínez Turrillas, Rebeca, Martínez Hernández, Jose, Kaltenbach, Linda S, Torres Peraza, Jesús Fernando, Graham, Rona K, Watanabe, Masahiko, Luján, Rafael, Nakanishi, Nobuki, Lipton, Stuart A, Lo, Donald C, Hayden, Michael R, Alberch i Vié, Jordi, 1959, Wesseling, John F, Pérez Otaño, Isabel

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Suppressing aberrant GluN3A expression rescues NMDA receptor dysfunction, synapse loss and motor and cognitive decline in Huntington's disease models von Marco, Sonia, Giralt, Albert, Petrovic, Milos M., Pouladi, Mahmoud A., Martínez-Turrillas, Rebeca, Martínez-Hernández, José, Kaltenbach, Linda S., Torres-Peraza, Jesús, Graham, Rona K., Watanabe, Masahiko, Luján, Rafael, Nakanishi, Nobuki, Lipton, Stuart A., Lo, Donald C., Hayden, Michael R., Alberch, Jordi, Wesseling, John F., Pérez-Otaño, Isabel

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