COVID-19 Transmission, Current Treatment, and Future Therapeutic Strategies von Salian, Vrishali S, Wright, Jessica A, Vedell, Peter T, Nair, Sanjana, Li, Chenxu, Kandimalla, Mahathi, Tang, Xiaojia, Carmona Porquera, Eva M, Kalari, Krishna R, Kandimalla, Karunya K

Volltext

Longitudinal Multi-omics Reveals Subset-Specific Mechanisms Underlying Irritable Bowel Syndrome von Mars, Ruben A.T., Yang, Yi, Ward, Tonya, Houtti, Mo, Priya, Sambhawa, Lekatz, Heather R., Tang, Xiaojia, Sun, Zhifu, Kalari, Krishna R., Korem, Tal, Bhattarai, Yogesh, Zheng, Tenghao, Bar, Noam, Frost, Gary, Johnson, Abigail J., van Treuren, Will, Han, Shuo, Ordog, Tamas, Grover, Madhusudan, Sonnenburg, Justin, D’Amato, Mauro, Camilleri, Michael, Elinav, Eran, Segal, Eran, Blekhman, Ran, Farrugia, Gianrico, Swann, Jonathan R., Knights, Dan, Kashyap, Purna C.

Volltext

Multiple sclerosis patients have a distinct gut microbiota compared to healthy controls von Chen, Jun, Chia, Nicholas, Kalari, Krishna R., Yao, Janet Z., Novotna, Martina, Paz Soldan, M. Mateo, Luckey, David H., Marietta, Eric V., Jeraldo, Patricio R., Chen, Xianfeng, Weinshenker, Brian G., Rodriguez, Moses, Kantarci, Orhun H., Nelson, Heidi, Murray, Joseph A., Mangalam, Ashutosh K.

Volltext

The Microbiome of Aseptically Collected Human Breast Tissue in Benign and Malignant Disease von Hieken, Tina J., Chen, Jun, Hoskin, Tanya L., Walther-Antonio, Marina, Johnson, Stephen, Ramaker, Sheri, Xiao, Jian, Radisky, Derek C., Knutson, Keith L., Kalari, Krishna R., Yao, Janet Z., Baddour, Larry M., Chia, Nicholas, Degnim, Amy C.

Volltext

FKBP51 Affects Cancer Cell Response to Chemotherapy by Negatively Regulating Akt von Pei, Huadong, Li, Liang, Fridley, Brooke L., Jenkins, Gregory D., Kalari, Krishna R., Lingle, Wilma, Petersen, Gloria, Lou, Zhenkun, Wang, Liewei

Volltext

DNA methyltransferase expression in triple-negative breast cancer predicts sensitivity to decitabine von Yu, Jia, Qin, Bo, Moyer, Ann M, Nowsheen, Somaira, Liu, Tongzheng, Qin, Sisi, Zhuang, Yongxian, Liu, Duan, Lu, Shijia W, Kalari, Krishna R, Visscher, Daniel W, Copland, John A, McLaughlin, Sarah A, Moreno-Aspitia, Alvaro, Northfelt, Donald W, Gray, Richard J, Lou, Zhenkun, Suman, Vera J, Weinshilboum, Richard, Boughey, Judy C, Goetz, Matthew P, Wang, Liewei

Volltext

Cell-level somatic mutation detection from single-cell RNA sequencing von Vu, Trung Nghia, Nguyen, Ha-Nam, Calza, Stefano, Kalari, Krishna R, Wang, Liewei, Pawitan, Yudi

Volltext

A comprehensive analysis of breast cancer microbiota and host gene expression von Thompson, Kevin J, Ingle, James N, Tang, Xiaojia, Chia, Nicholas, Jeraldo, Patricio R, Walther-Antonio, Marina R, Kandimalla, Karunya K, Johnson, Stephen, Yao, Janet Z, Harrington, Sean C, Suman, Vera J, Wang, Liewei, Weinshilboum, Richard L, Boughey, Judy C, Kocher, Jean-Pierre, Nelson, Heidi, Goetz, Matthew P, Kalari, Krishna R

Volltext

Knowledge-guided gene prioritization reveals new insights into the mechanisms of chemoresistance von Emad, Amin, Cairns, Junmei, Kalari, Krishna R, Wang, Liewei, Sinha, Saurabh

Volltext

A cell cycle-dependent BRCA1–UHRF1 cascade regulates DNA double-strand break repair pathway choice von Zhang, Haoxing, Liu, Hailong, Chen, Yali, Yang, Xu, Wang, Panfei, Liu, Tongzheng, Deng, Min, Qin, Bo, Correia, Cristina, Lee, Seungbaek, Kim, Jungjin, Sparks, Melanie, Nair, Asha A., Evans, Debra L., Kalari, Krishna R., Zhang, Pumin, Wang, Liewei, You, Zhongsheng, Kaufmann, Scott H., Lou, Zhenkun, Pei, Huadong

Volltext

OmicsFootPrint: a framework to integrate and interpret multi-omics data using circular images and deep neural networks von Tang, Xiaojia, Prodduturi, Naresh, Thompson, Kevin J, Weinshilboum, Richard, O'Sullivan, Ciara C, Boughey, Judy C, Tizhoosh, Hamid R, Klee, Eric W, Wang, Liewei, Goetz, Matthew P, Suman, Vera, Kalari, Krishna R

Volltext

Folate receptor-α (FOLR1) expression and function in triple negative tumors von Necela, Brian M, Crozier, Jennifer A, Andorfer, Cathy A, Lewis-Tuffin, Laura, Kachergus, Jennifer M, Geiger, Xochiquetzal J, Kalari, Krishna R, Serie, Daniel J, Sun, Zhifu, Moreno-Aspitia, Alvaro, Aspita, Alvaro Moreno, O'Shannessy, Daniel J, Maltzman, Julia D, McCullough, Ann E, Pockaj, Barbara A, Cunliffe, Heather E, Ballman, Karla V, Thompson, E Aubrey, Perez, Edith A

Volltext

The lncRNA MIR2052HG regulates ERα levels and aromatase inhibitor resistance through LMTK3 by recruiting EGR1 von Cairns, Junmei, Ingle, James N, Kalari, Krishna R, Shepherd, Lois E, Kubo, Michiaki, Goetz, Matthew P, Weinshilboum, Richard M, Wang, Liewei

Volltext

SLCO1B1: Application and Limitations of Deep Mutational Scanning for Genomic Missense Variant Function von Zhang, Lingxin, Sarangi, Vivekananda, Ho, Ming-Fen, Moon, Irene, Kalari, Krishna R., Wang, Liewei, Weinshilboum, Richard M.

Volltext

Impact of histopathology, tumor-infiltrating lymphocytes, and adjuvant chemotherapy on prognosis of triple-negative breast cancer von Leon-Ferre, Roberto A., Polley, Mei-Yin, Liu, Heshan, Gilbert, Judith A., Cafourek, Victoria, Hillman, David W., Elkhanany, Ahmed, Akinhanmi, Margaret, Lilyquist, Jenna, Thomas, Abigail, Negron, Vivian, Boughey, Judy C., Liu, Minetta C., Ingle, James N., Kalari, Krishna R., Couch, Fergus J., Visscher, Daniel W., Goetz, Matthew P.

Volltext

Knowledge-guided analysis of "omics" data using the KnowEnG cloud platform von Blatti, Charles, Emad, Amin, Berry, Matthew J., Gatzke, Lisa, Epstein, Milt, Lanier, Daniel, Rizal, Pramod, Ge, Jing, Liao, Xiaoxia, Sobh, Omar, Lambert, Mike, Post, Corey S., Xiao, Jinfeng, Groves, Peter, Epstein, Aidan T., Chen, Xi, Srinivasan, Subhashini, Lehnert, Erik, Kalari, Krishna R., Wang, Liewei, Weinshilboum, Richard M., Song, Jun S., Jongeneel, C. Victor, Han, Jiawei, Ravaioli, Umberto, Sobh, Nahil, Bushell, Colleen B., Sinha, Saurabh

Volltext

Discovery of a Glucocorticoid Receptor (GR) Activity Signature Using Selective GR Antagonism in ER-Negative Breast Cancer von West, Diana C, Kocherginsky, Masha, Tonsing-Carter, Eva Y, Dolcen, D Nesli, Hosfield, David J, Lastra, Ricardo R, Sinnwell, Jason P, Thompson, Kevin J, Bowie, Kathleen R, Harkless, Ryan V, Skor, Maxwell N, Pierce, Charles F, Styke, Sarah C, Kim, Caroline R, de Wet, Larischa, Greene, Geoffrey L, Boughey, Judy C, Goetz, Matthew P, Kalari, Krishna R, Wang, Liewei, Fleming, Gini F, Györffy, Balázs, Conzen, Suzanne D

Volltext

Trinucleotide Repeat Expansion in the Transcription Factor 4 (TCF4) Gene Leads to Widespread mRNA Splicing Changes in Fuchs' Endothelial Corneal Dystrophy von Wieben, Eric D, Aleff, Ross A, Tang, Xiaojia, Butz, Malinda L, Kalari, Krishna R, Highsmith, Edward W, Jen, Jin, Vasmatzis, George, Patel, Sanjay V, Maguire, Leo J, Baratz, Keith H, Fautsch, Michael P

Volltext

Gene expression in the corneal endothelium of Fuchs endothelial corneal dystrophy patients with and without expansion of a trinucleotide repeat in TCF4 von Wieben, Eric D, Aleff, Ross A, Tang, Xiaojia, Kalari, Krishna R, Maguire, Leo J, Patel, Sanjay V, Baratz, Keith H, Fautsch, Michael P

Volltext

Integrated analysis of gene expression, CpG island methylation, and gene copy number in breast cancer cells by deep sequencing von Sun, Zhifu, Asmann, Yan W, Kalari, Krishna R, Bot, Brian, Eckel-Passow, Jeanette E, Baker, Tiffany R, Carr, Jennifer M, Khrebtukova, Irina, Luo, Shujun, Zhang, Lu, Schroth, Gary P, Perez, Edith A, Thompson, E Aubrey

Volltext