Discovery of novel S1P2 antagonists. Part 1: Discovery of 1,3-bis(aryloxy)benzene derivatives von Kusumi, Kensuke, Shinozaki, Koji, Kanaji, Toshiya, Kurata, Haruto, Naganawa, Atsushi, Otsuki, Kazuhiro, Matsushita, Takeshi, Sekiguchi, Tetsuya, Kakuuchi, Akito, Seko, Takuya

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Synthesis and evaluation of a potent, well-balanced EP 2 /EP 3 dual agonist von Kinoshita, Akihiro, Higashino, Masato, Yoshida, Koji, Aratani, Yoshiyuki, Kakuuchi, Akito, Hanada, Keisuke, Takeda, Hiroyuki, Naganawa, Atsushi, Matsuya, Hidekazu, Ohmoto, Kazuyuki

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Discovery of novel S1P2 antagonists, part 3: Improving the oral bioavailability of a series of 1,3-bis(aryloxy)benzene derivatives von Kusumi, Kensuke, Shinozaki, Koji, Yamaura, Yoshiyuki, Hashimoto, Ai, Kurata, Haruto, Naganawa, Atsushi, Otsuki, Kazuhiro, Matsushita, Takeshi, Sekiguchi, Tetsuya, Kakuuchi, Akito, Yamamoto, Hiroshi, Seko, Takuya

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Discovery of novel S1P2 antagonists. Part 2: Improving the profile of a series of 1,3-bis(aryloxy)benzene derivatives von Kusumi, Kensuke, Shinozaki, Koji, Yamaura, Yoshiyuki, Hashimoto, Ai, Kurata, Haruto, Naganawa, Atsushi, Ueda, Hideyuki, Otsuki, Kazuhiro, Matsushita, Takeshi, Sekiguchi, Tetsuya, Kakuuchi, Akito, Seko, Takuya

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Post-marketing surveillance of the safety and effectiveness of nivolumab for classic Hodgkin lymphoma in Japan von Kawasaki, Akira, Hatake, Kiyohiko, Matsumura, Itaru, Izutsu, Koji, Hoshino, Tomohiro, Akamatsu, Ayumi, Kakuuchi, Akito, Tobinai, Kensei

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Rh(I)-catalyzed conjugate addition of alkenylzirconocene chloride: stereoselective formation of carbocycles through cascade reaction von Hanzawa, Yuji, Takebe, Yoshitaka, Saito, Akio, Kakuuchi, Akito, Fukaya, Haruhiko

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Rhodium-catalyzed 1,4-addition of alkenylzirconocene chlorides to electron deficient alkenes von Kakuuchi, Akito, Taguchi, Takeo, Hanzawa, Yuji

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Rh(I)-catalyzed addition of alkenylzirconocene chlorides to aldimine derivatives von Kakuuchi, Akito, Taguchi, Takeo, Hanzawa, Yuji

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Discovery of highly potent dual EP2 and EP3 agonists with subtype selectivity von Kinoshita, Akihiro, Higashino, Masato, Aratani, Yoshiyuki, Kakuuchi, Akito, Matsuya, Hidekazu, Ohmoto, Kazuyuki

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Discovery of highly potent dual EP 2 and EP 3 agonists with subtype selectivity von Kinoshita, Akihiro, Higashino, Masato, Aratani, Yoshiyuki, Kakuuchi, Akito, Matsuya, Hidekazu, Ohmoto, Kazuyuki

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Discovery of highly potent dual EP sub(2) and EP sub(3) agonists with subtype selectivity von Kinoshita, Akihiro, Higashino, Masato, Aratani, Yoshiyuki, Kakuuchi, Akito, Matsuya, Hidekazu, Ohmoto, Kazuyuki

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Yb(OTf) 3–TMSOTf-catalyzed reactions of acylzirconocene chloride to imines von Kakuuchi, Akito, Taguchi, Takeo, Hanzawa, Yuji

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Synthesis of 2-fluoro analog of 6-aminonorbornane-2,6-dicarboxylic acid: A conformationally rigid glutamic acid derivative von Ito, Hisanaka, Saito, Akio, Kakuuchi, Akito, Taguchi, Takeo

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Synthesis and evaluation of a potent, well-balanced EP2/EP3 dual agonist von Kinoshita, Akihiro, Higashino, Masato, Yoshida, Koji, Aratani, Yoshiyuki, Kakuuchi, Akito, Hanada, Keisuke, Takeda, Hiroyuki, Naganawa, Atsushi, Matsuya, Hidekazu, Ohmoto, Kazuyuki

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Discovery of highly potent dual EP(2) and EP(3) agonists with subtype selectivity von Kinoshita, Akihiro, Higashino, Masato, Aratani, Yoshiyuki, Kakuuchi, Akito, Matsuya, Hidekazu, Ohmoto, Kazuyuki

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Discovery of novel S1P sub(2) antagonists, part 3: Improving the oral bioavailability of a series of 1,3-bis(aryloxy)benzene derivatives von Kusumi, Kensuke, Shinozaki, Koji, Yamaura, Yoshiyuki, Hashimoto, Ai, Kurata, Haruto, Naganawa, Atsushi, Otsuki, Kazuhiro, Matsushita, Takeshi, Sekiguchi, Tetsuya, Kakuuchi, Akito, Yamamoto, Hiroshi, Seko, Takuya

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Formation of α-Amino Ketones: Addition of Acylzirconocene Chlorides to Imines Catalyzed by Yb(OTf)3/TmsOTf and Brønsted Acids and Three-Component Reactions of Acylzirconocene Chlor... von Kakuuchi, Akito, Taguchi, Takeo, Hanzawa, Yuji

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Pd-catalyzed regioselective acylation of α,β-unsaturated ketone derivatives by acylzirconocene chloride as an acyl group donor von Hanzawa, Yuji, Tabuchi, Nobuhito, Narita, Kensuke, Kakuuchi, Akito, Yabe, Masaya, Taguchi, Takeo

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CRYSTAL OF AZABICYCLO RING COMPOUND von HIRAMATSU ATSUSHI, KAKUUCHI AKITO

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3-AZABICYCLO(3.1.0)HEXANE DERIVATIVES HAVING KDM5 INHIBITORY ACTIVITY AND USE THEREOF von UMEMURA, Shuhei, KRILOV, Goran, KAKUUCHI, Akito, RUVINSKY, Anatoly, ZHANG, Yan, ASADA, Masaki, TAKAHASHI, Hidenori, SVENSSON, Mats, INOYAMA, Daigo, KONZE, Kyle

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