U2AF1 mutations induce oncogenic IRAK4 isoforms and activate innate immune pathways in myeloid malignancies von Smith, Molly A., Choudhary, Gaurav S., Pellagatti, Andrea, Choi, Kwangmin, Bolanos, Lyndsey C., Bhagat, Tushar D., Gordon-Mitchell, Shanisha, Von Ahrens, Dagny, Pradhan, Kith, Steeples, Violetta, Kim, Sanghyun, Steidl, Ulrich, Walter, Matthew, Fraser, Iain D. C., Kulkarni, Aishwarya, Salomonis, Nathan, Komurov, Kakajan, Boultwood, Jacqueline, Verma, Amit, Starczynowski, Daniel T.

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NetWalker: a contextual network analysis tool for functional genomics von Komurov, Kakajan, Dursun, Serkan, Erdin, Serkan, Ram, Prahlad T

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Drug resistance mechanisms create targetable proteostatic vulnerabilities in Her2+ breast cancers von Navneet Singh, Lindsey Romick-Rosendale, Miki Watanabe-Chailland, Lisa M. Privette Vinnedge, Kakajan Komurov

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Core epithelial-to-mesenchymal transition interactome gene-expression signature is associated with claudin-low and metaplastic breast cancer subtypes von Taube, Joseph H., Herschkowitz, Jason I., Komurov, Kakajan, Zhou, Alicia Y., Gupta, Supriya, Yang, Jing, Hartwell, Kimberly, Onder, Tamer T., Gupta, Piyush B., Evans, Kurt W., Hollier, Brett G., Ram, Prahlad T., Lander, Eric S., Rosen, Jeffrey M., Weinberg, Robert A., Mani, Sendurai A.

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Targeting c-FOS and DUSP1 abrogates intrinsic resistance to tyrosine-kinase inhibitor therapy in BCR-ABL-induced leukemia von Kesarwani, Meenu, Kincaid, Zachary, Gomaa, Ahmed, Huber, Erika, Rohrabaugh, Sara, Siddiqui, Zain, Bouso, Muhammad F, Latif, Tahir, Xu, Ming, Komurov, Kakajan, Mulloy, James C, Cancelas, Jose A, Grimes, H Leighton, Azam, Mohammad

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Revealing static and dynamic modular architecture of the eukaryotic protein interaction network von Komurov, Kakajan, White, Michael

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Drug resistance mechanisms create targetable proteostatic vulnerabilities in Her2+ breast cancers von Singh, Navneet, Romick-Rosendale, Lindsey, Watanabe-Chailland, Miki, Privette Vinnedge, Lisa M, Komurov, Kakajan

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Suppression of tumor antigen presentation during aneuploid tumor evolution contributes to immune evasion von Tripathi, Reshmi, Modur, Vishnu, Senovilla, Laura, Kroemer, Guido, Komurov, Kakajan

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A calcium- and calpain-dependent pathway determines the response to lenalidomide in myelodysplastic syndromes von Fang, Jing, Liu, Xiaona, Bolanos, Lyndsey, Barker, Brenden, Rigolino, Carmela, Cortelezzi, Agostino, Oliva, Esther N, Cuzzola, Maria, Grimes, H Leighton, Fontanillo, Celia, Komurov, Kakajan, MacBeth, Kyle, Starczynowski, Daniel T

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Basal and Treatment-Induced Activation of AKT Mediates Resistance to Cell Death by AZD6244 (ARRY-142886) in Braf-Mutant Human Cutaneous Melanoma Cells von VASHISHT GOPAL, Y. N, WANLENG DENG, WOODMAN, Scott E, KOMUROV, Kakajan, RAM, Prahlad, SMITH, Paul D, DAVIES, Michael A

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Mechanism of inert inflammation in an immune checkpoint blockade-resistant tumor subtype bearing transcription elongation defects von Modur, Vishnu, Muhammad, Belal, Yang, Jun-Qi, Zheng, Yi, Komurov, Kakajan, Guo, Fukun

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Systematic Identification of Molecular Subtype-Selective Vulnerabilities in Non-Small-Cell Lung Cancer von Kim, Hyun Seok, Mendiratta, Saurabh, Kim, Jiyeon, Pecot, Chad Victor, Larsen, Jill E., Zubovych, Iryna, Seo, Bo Yeun, Kim, Jimi, Eskiocak, Banu, Chung, Hannah, McMillan, Elizabeth, Wu, Sherry, De Brabander, Jef, Komurov, Kakajan, Toombs, Jason E., Wei, Shuguang, Peyton, Michael, Williams, Noelle, Gazdar, Adi F., Posner, Bruce A., Brekken, Rolf A., Sood, Anil K., Deberardinis, Ralph J., Roth, Michael G., Minna, John D., White, Michael A.

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Use of data-biased random walks on graphs for the retrieval of context-specific networks from genomic data von Komurov, Kakajan, White, Michael A, Ram, Prahlad T

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Tumor Cell Autonomous RON Receptor Expression Promotes Prostate Cancer Growth Under Conditions of Androgen Deprivation von Brown, Nicholas E., Paluch, Andrew M., Nashu, Madison A., Komurov, Kakajan, Waltz, Susan E.

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The glucose‐deprivation network counteracts lapatinib‐induced toxicity in resistant ErbB2‐positive breast cancer cells von Komurov, Kakajan, Tseng, Jen‐Te, Muller, Melissa, Seviour, Elena G, Moss, Tyler J, Yang, Lifeng, Nagrath, Deepak, Ram, Prahlad T

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Defective transcription elongation in a subset of cancers confers immunotherapy resistance von Modur, Vishnu, Singh, Navneet, Mohanty, Vakul, Chung, Eunah, Muhammad, Belal, Choi, Kwangmin, Chen, Xiaoting, Chetal, Kashish, Ratner, Nancy, Salomonis, Nathan, Weirauch, Matthew T., Waltz, Susan, Huang, Gang, Privette-Vinnedge, Lisa, Park, Joo-Seop, Janssen, Edith M., Komurov, Kakajan

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Biomarker Accessible and Chemically Addressable Mechanistic Subtypes of BRAF Melanoma von Eskiocak, Banu, McMillan, Elizabeth A, Mendiratta, Saurabh, Kollipara, Rahul K, Zhang, Hailei, Humphries, Caroline G, Wang, Changguang, Garcia-Rodriguez, Jose, Ding, Ming, Zaman, Aubhishek, Rosales, Tracy I, Eskiocak, Ugur, Smith, Michael P, Sudderth, Jessica, Komurov, Kakajan, Deberardinis, Ralph J, Wellbrock, Claudia, Davies, Michael A, Wargo, Jennifer A, Yu, Yonghao, De Brabander, Jef K, Williams, Noelle S, Chin, Lynda, Rizos, Helen, Long, Georgina V, Kittler, Ralf, White, Michael A

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Dek overexpression in murine epithelia increases overt esophageal squamous cell carcinoma incidence von Matrka, Marie C, Cimperman, Katherine A, Haas, Sarah R, Guasch, Geraldine, Ehrman, Lisa A, Waclaw, Ronald R, Komurov, Kakajan, Lane, Adam, Wikenheiser-Brokamp, Kathryn A, Wells, Susanne I

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Mechanisms of stearoyl CoA desaturase inhibitor sensitivity and acquired resistance in cancer von Oatman, Nicole, Dasgupta, Nupur, Arora, Priyanka, Choi, Kwangmin, Gawali, Mruniya, Gupta, Nishtha, Parameswaran, Sreeja, Salomone, Joseph, Reisz, Julie A., Lawler, Sean, Furnari, Frank, Brennan, Cameron, Wu, Jianqiang, Sallans, Larry, Gudelsky, Gary, Desai, Pankaj, Gebelein, Brian, Weirauch, Matthew T., D'Alessandro, Angelo, Komurov, Kakajan, Dasgupta, Biplab

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mTOR Kinase Inhibition Effectively Decreases Progression of a Subset of Neuroendocrine Tumors that Progress on Rapalog Therapy and Delays Cardiac Impairment von Orr-Asman, Melissa A, Chu, Zhengtao, Jiang, Min, Worley, Mariah, LaSance, Kathleen, Koch, Sheryl E, Carreira, Vinicius S, Dahche, Hanan M, Plas, David R, Komurov, Kakajan, Qi, Xiaoyang, Mercer, Carol A, Anthony, Lowell B, Rubinstein, Jack, Thomas, Hala E

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