The transcriptional corepressor CtBP2 serves as a metabolite sensor orchestrating hepatic glucose and lipid homeostasis von Sekiya, Motohiro, Kainoh, Kenta, Sugasawa, Takehito, Yoshino, Ryunosuke, Hirokawa, Takatsugu, Tokiwa, Hiroaki, Nakano, Shogo, Nagatoishi, Satoru, Tsumoto, Kouhei, Takeuchi, Yoshinori, Miyamoto, Takafumi, Matsuzaka, Takashi, Shimano, Hitoshi

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Obesity-induced metabolic imbalance allosterically modulates CtBP2 to inhibit PPAR-alpha transcriptional activity von Saito, Kenji, Sekiya, Motohiro, Kainoh, Kenta, Yoshino, Ryunosuke, Hayashi, Akio, Han, Song-Iee, Araki, Masaya, Ohno, Hiroshi, Takeuchi, Yoshinori, Tsuyuzaki, Tomomi, Yamazaki, Daichi, Wanpei, Chen, Hada, Lisa, Watanabe, Sho, Paramita Adi Putri, Putu Indah, Murayama, Yuki, Sugano, Yoko, Osaki, Yoshinori, Iwasaki, Hitoshi, Yahagi, Naoya, Suzuki, Hiroaki, Miyamoto, Takafumi, Matsuzaka, Takashi, Shimano, Hitoshi

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C-Terminal Binding Protein 2 Emerges as a Critical Player Linking Metabolic Imbalance to the Pathogenesis of Obesity von Sekiya, Motohiro, Kainoh, Kenta, Saito, Kenji, Yamazaki, Daichi, Tsuyuzaki, Tomomi, Chen, Wanpei, Kobari, Yuto, Nakata, Ayumi, Babe, Haruka, Shimano, Hitoshi

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Loss of CtBP2 may be a mechanistic link between metabolic derangements and progressive impairment of pancreatic β cell function von Sekiya, Motohiro, Ma, Yang, Kainoh, Kenta, Saito, Kenji, Yamazaki, Daichi, Tsuyuzaki, Tomomi, Chen, Wanpei, Adi Putri, Putu Indah Paramita, Ohno, Hiroshi, Miyamoto, Takafumi, Takeuchi, Yoshinori, Murayama, Yuki, Sugano, Yoko, Osaki, Yoshinori, Iwasaki, Hitoshi, Yahagi, Naoya, Suzuki, Hiroaki, Motomura, Kaori, Matsuzaka, Takashi, Murata, Kazuya, Mizuno, Seiya, Takahashi, Satoru, Shimano, Hitoshi

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Genetic and Functional Analyses of Patients with Marked Hypo-High-Density Lipoprotein Cholesterolemia von Furuta, Yasuhisa, Osaki, Yoshinori, Nakagawa, Yoshimi, Han, Song-Iee, Araki, Masaya, Shikama, Akito, Ohuchi, Nami, Yamazaki, Daichi, Matsuda, Erika, Nohara, Seitaro, Mizunoe, Yuhei, Kainoh, Kenta, Suehara, Yasuhito, Ohno, Hiroshi, Takeuchi, Yoshinori, Miyamoto, Takafumi, Murayama, Yuki, Sugano, Yoko, Iwasaki, Hitoshi, Hirano, Ken-ichi, Koseki, Masahiro, Nakano, Shogo, Tokiwa, Hiroaki, Sekiya, Motohiro, Yahagi, Naoya, Matsuzaka, Takashi, Nakamagoe, Kiyotaka, Tomidokoro, Yasushi, Mitsui, Jun, Tsuji, Shoji, Suzuki, Hiroaki, Shimano, Hitoshi

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Rhomboid protease RHBDL4/RHBDD1 cleaves SREBP-1c at endoplasmic reticulum monitoring and regulating fatty acids von Han, Song-Iee, Nakakuki, Masanori, Nakagawa, Yoshimi, Wang, Yunong, Araki, Masaya, Yamamoto, Yuta, Tokiwa, Hiroaki, Takeda, Hiroyuki, Mizunoe, Yuhei, Motomura, Kaori, Ohno, Hiroshi, Kainoh, Kenta, Murayama, Yuki, Aita, Yuichi, Takeuchi, Yoshinori, Osaki, Yoshinori, Miyamoto, Takafumi, Sekiya, Motohiro, Matsuzaka, Takashi, Yahagi, Naoya, Sone, Hirohito, Daitoku, Hiroaki, Sato, Ryuichiro, Kawano, Hiroyuki, Shimano, Hitoshi

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C-Terminal Binding Protein 2 Emerges as a Critical Player Linking Metabolic Imbalance to the Pathogenesis of Obesity von Motohiro Sekiya, Kenta Kainoh, Kenji Saito, Daichi Yamazaki, Tomomi Tsuyuzaki, Wanpei Chen, Yuto Kobari, Ayumi Nakata, Haruka Babe, Hitoshi Shimano

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C-Terminal Binding Protein 2 Emerges as a Critical Player Linking Metabolic Imbalance to the Pathogenesis of Obesity von Sekiya, Motohiro, Kainoh, Kenta, Saito, Kenji, Yamazaki, Daichi, Tsuyuzaki, Tomomi, Chen, Wanpei, Kobari, Yuto, Nakata, Ayumi, Babe, Haruka, Shimano, Hitoshi

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Transcriptional co-repressor CtBP2 orchestrates epithelial-mesenchymal transition through a novel transcriptional holocomplex with OCT1 von Ma, Yang, Sekiya, Motohiro, Kainoh, Kenta, Matsuda, Takaaki, Iwasaki, Hitoshi, Osaki, Yoshinori, Sugano, Yoko, Suzuki, Hiroaki, Takeuchi, Yoshinori, Miyamoto, Takafumi, Yahagi, Naoya, Nakagawa, Yoshimi, Matsuzaka, Takashi, Shimano, Hitoshi

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CtBP2 confers protection against oxidative stress through interactions with NRF1 and NRF2 von Kainoh, Kenta, Takano, Ryo, Sekiya, Motohiro, Saito, Kenji, Sugasawa, Takehito, Ma, Yang, Murayama, Yuki, Sugano, Yoko, Osaki, Yoshinori, Iwasaki, Hitoshi, Takeuchi, Yoshinori, Yahagi, Naoya, Suzuki, Hiroaki, Miyamoto, Takafumi, Nakagawa, Yoshimi, Matsuzaka, Takashi, Shimano, Hitoshi

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Genetic and Functional Analyses of Patients with Marked Hypo-High-Density Lipoprotein Cholesterolemia von Furuta, Yasuhisa, Osaki, Yoshinori, Nakagawa, Yoshimi, Han, Song-Iee, Araki, Masaya, Shikama, Akito, Ohuchi, Nami, Yamazaki, Daichi, Matsuda, Erika, Nohara, Seitaro, Mizunoe, Yuhei, Kainoh, Kenta, Suehara, Yasuhito, Ohno, Hiroshi, Takeuchi, Yoshinori, Miyamoto, Takafumi, Murayama, Yuki, Sugano, Yoko, Iwasaki, Hitoshi, Hirano, Ken-ichi, Koseki, Masahiro, Nakano, Shogo, Tokiwa, Hiroaki, Sekiya, Motohiro, Yahagi, Naoya, Matsuzaka, Takashi, Nakamagoe, Kiyotaka, Tomidokoro, Yasushi, Mitsui, Jun, Tsuji, Shoji, Suzuki, Hiroaki, Shimano, Hitoshi

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Genetic and Functional Analyses of Patients with Marked Hypo-High-Density Lipoprotein Cholesterolemia von Yasuhisa Furuta, Yoshinori Osaki, Yoshimi Nakagawa, Song-Iee Han, Masaya Araki, Akito Shikama, Nami Ohuchi, Daichi Yamazaki, Erika Matsuda, Seitaro Nohara, Yuhei Mizunoe, Kenta Kainoh, Yasuhito Suehara, Hiroshi Ohno, Yoshinori Takeuchi, Takafumi Miyamoto, Yuki Murayama, Yoko Sugano, Hitoshi Iwasaki, Ken-ichi Hirano, Masahiro Koseki, Shogo Nakano, Hiroaki Tokiwa, Motohiro Sekiya, Naoya Yahagi, Takashi Matsuzaka, Kiyotaka Nakamagoe, Yasushi Tomidokoro, Jun Mitsui, Shoji Tsuji, Hiroaki Suzuki, Hitoshi Shimano

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