Syntaxin 17 regulates the localization and function of PGAM5 in mitochondrial division and mitophagy von Sugo, Masashi, Kimura, Hana, Arasaki, Kohei, Amemiya, Toshiki, Hirota, Naohiko, Dohmae, Naoshi, Imai, Yuzuru, Inoshita, Tsuyoshi, Shiba‐Fukushima, Kahori, Hattori, Nobutaka, Cheng, Jinglei, Fujimoto, Toyoshi, Wakana, Yuichi, Inoue, Hiroki, Tagaya, Mitsuo

Volltext

α‐Synuclein V15A Variant in Familial Parkinson's Disease Exhibits a Weaker Lipid‐Binding Property von Daida, Kensuke, Shimonaka, Shotaro, Shiba‐Fukushima, Kahori, Ogata, Jun, Yoshino, Hiroyo, Okuzumi, Ayami, Hatano, Taku, Motoi, Yumiko, Hirunagi, Tomoki, Katsuno, Masahisa, Shindou, Hideo, Funayama, Manabu, Nishioka, Kenya, Hattori, Nobutaka, Imai, Yuzuru

Volltext

PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy von Matsuda, Noriyuki, Sato, Shigeto, Shiba, Kahori, Okatsu, Kei, Saisho, Keiko, Gautier, Clement A, Sou, Yu-shin, Saiki, Shinji, Kawajiri, Sumihiro, Sato, Fumiaki, Kimura, Mayumi, Komatsu, Masaaki, Hattori, Nobutaka, Tanaka, Keiji

Volltext

In Vivo Evidence for the Involvement of Phospho-Ubiquitin Signal von Kahori Shiba

Volltext

PINK1-mediated phosphorylation of the Parkin ubiquitin-like domain primes mitochondrial translocation of Parkin and regulates mitophagy von Shiba-Fukushima, Kahori, Imai, Yuzuru, Yoshida, Shigeharu, Ishihama, Yasushi, Kanao, Tomoko, Sato, Shigeto, Hattori, Nobutaka

Volltext

Twin CHCH Proteins, CHCHD2, and CHCHD10: Key Molecules of Parkinson's Disease, Amyotrophic Lateral Sclerosis, and Frontotemporal Dementia von Imai, Yuzuru, Meng, Hongrui, Shiba-Fukushima, Kahori, Hattori, Nobutaka

Volltext

Loss of Parkinson’s disease-associated protein CHCHD2 affects mitochondrial crista structure and destabilizes cytochrome c von Meng, Hongrui, Yamashita, Chikara, Shiba-Fukushima, Kahori, Inoshita, Tsuyoshi, Funayama, Manabu, Sato, Shigeto, Hatta, Tomohisa, Natsume, Tohru, Umitsu, Masataka, Takagi, Junichi, Imai, Yuzuru, Hattori, Nobutaka

Volltext

Parkinson disease-associated Leucine-rich repeat kinase regulates UNC-104-dependent axonal transport of Arl8-positive vesicles in Drosophila von Inoshita, Tsuyoshi, Liu, Jun-Yi, Taniguchi, Daisuke, Ishii, Ryota, Shiba-Fukushima, Kahori, Hattori, Nobutaka, Imai, Yuzuru

Volltext

PINK1 autophosphorylation upon membrane potential dissipation is essential for Parkin recruitment to damaged mitochondria von Okatsu, Kei, Oka, Toshihiko, Iguchi, Masahiro, Imamura, Kenji, Kosako, Hidetaka, Tani, Naoki, Kimura, Mayumi, Go, Etsu, Koyano, Fumika, Funayama, Manabu, Shiba-Fukushima, Kahori, Sato, Shigeto, Shimizu, Hideaki, Fukunaga, Yuko, Taniguchi, Hisaaki, Komatsu, Masaaki, Hattori, Nobutaka, Mihara, Katsuyoshi, Tanaka, Keiji, Matsuda, Noriyuki

Volltext

Loss of nuclear REST/NRSF in aged-dopaminergic neurons in Parkinson’s disease patients von Kawamura, Miwako, Sato, Shigeto, Matsumoto, Gen, Fukuda, Takahiro, Shiba-Fukushima, Kahori, Noda, Sachiko, Takanashi, Masashi, Mori, Nozomu, Hattori, Nobutaka

Volltext

PINK1-mediated phosphorylation of Parkin boosts Parkin activity in Drosophila von Shiba-Fukushima, Kahori, Inoshita, Tsuyoshi, Hattori, Nobutaka, Imai, Yuzuru

Volltext

Phosphorylation of mitochondrial polyubiquitin by PINK1 promotes Parkin mitochondrial tethering von Shiba-Fukushima, Kahori, Arano, Taku, Matsumoto, Gen, Inoshita, Tsuyoshi, Yoshida, Shigeharu, Ishihama, Yasushi, Ryu, Kwon-Yul, Nukina, Nobuyuki, Hattori, Nobutaka, Imai, Yuzuru

Volltext

Light-driven activation of mitochondrial proton-motive force improves motor behaviors in a Drosophila model of Parkinson’s disease von Imai, Yuzuru, Inoshita, Tsuyoshi, Meng, Hongrui, Shiba-Fukushima, Kahori, Hara, Kiyotaka Y., Sawamura, Naoya, Hattori, Nobutaka

Volltext

Ubiquitination at the lysine 27 residue of the Parkin ubiquitin-like domain is suggestive of a new mechanism of Parkin activation von Liu, Jun-Yi, Inoshita, Tsuyoshi, Shiba-Fukushima, Kahori, Yoshida, Shigeharu, Ogata, Kosuke, Ishihama, Yasushi, Imai, Yuzuru, Hattori, Nobutaka

Volltext

Tricornered/NDR kinase signaling mediates PINK1-directed mitochondrial quality control and tissue maintenance von Wu, Zhihao, Sawada, Tomoyo, Shiba, Kahori, Liu, Song, Kanao, Tomoko, Takahashi, Ryosuke, Hattori, Nobutaka, Imai, Yuzuru, Lu, Bingwei

Volltext

Identifying Therapeutic Agents for Amelioration of Mitochondrial Clearance Disorder in Neurons of Familial Parkinson Disease von Yamaguchi, Akihiro, Ishikawa, Kei-ichi, Inoshita, Tsuyoshi, Shiba-Fukushima, Kahori, Saiki, Shinji, Hatano, Taku, Mori, Akio, Oji, Yutaka, Okuzumi, Ayami, Li, Yuanzhe, Funayama, Manabu, Imai, Yuzuru, Hattori, Nobutaka, Akamatsu, Wado

Volltext

Clinical characteristics and pathophysiological properties of newly discovered LRRK2 variants associated with Parkinson's disease von Tezuka, Toshiki, Ishiguro, Mayu, Taniguchi, Daisuke, Osogaguchi, Ehoto, Shiba-Fukushima, Kahori, Ogata, Jun, Ishii, Ryota, Ikeda, Aya, Li, Yuanzhe, Yoshino, Hiroyo, Matsui, Taro, Kaida, Kenichi, Funayama, Manabu, Nishioka, Kenya, Kumazawa, Fumihisa, Matsubara, Tomoyasu, Tsuda, Hitoshi, Saito, Yuko, Murayama, Shigeo, Imai, Yuzuru, Hattori, Nobutaka

Volltext

Monitoring Mitochondrial Changes by Alteration of the PINK1-Parkin Signaling in Drosophila von Inoshita, Tsuyoshi, Shiba-Fukushima, Kahori, Meng, Hongrui, Hattori, Nobutaka, Imai, Yuzuru

Volltext

A Cell-Based High-Throughput Screening Identified Two Compounds that Enhance PINK1-Parkin Signaling von Shiba-Fukushima, Kahori, Inoshita, Tsuyoshi, Sano, Osamu, Iwata, Hidehisa, Ishikawa, Kei-ichi, Okano, Hideyuki, Akamatsu, Wado, Imai, Yuzuru, Hattori, Nobutaka

Volltext

Pathophysiological evaluation of the LRRK2 G2385R risk variant for Parkinson’s disease von Tezuka, Toshiki, Taniguchi, Daisuke, Sano, Mariko, Shimada, Tomoyo, Oji, Yutaka, Tsunemi, Taiji, Ikeda, Aya, Li, Yuanzhe, Yoshino, Hiroyo, Ogata, Jun, Shiba-Fukushima, Kahori, Funayama, Manabu, Nishioka, Kenya, Imai, Yuzuru, Hattori, Nobutaka

Volltext