Fibroblast Subtypes Regulate Responsiveness of Luminal Breast Cancer to Estrogen von Brechbuhl, Heather M, Finlay-Schultz, Jessica, Yamamoto, Tomomi M, Gillen, Austin E, Cittelly, Diana M, Tan, Aik-Choon, Sams, Sharon B, Pillai, Manoj M, Elias, Anthony D, Robinson, William A, Sartorius, Carol A, Kabos, Peter

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New generation breast cancer cell lines developed from patient-derived xenografts von Finlay-Schultz, Jessica, Jacobsen, Britta M., Riley, Duncan, Paul, Kiran V., Turner, Scott, Ferreira-Gonzalez, Andrea, Harrell, J. Chuck, Kabos, Peter, Sartorius, Carol A.

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Combination of Trastuzumab Emtansine and Stereotactic Radiosurgery Results in High Rates of Clinically Significant Radionecrosis and Dysregulation of Aquaporin-4 von Stumpf, Priscilla K, Cittelly, Diana M, Robin, Tyler P, Carlson, Julie A, Stuhr, Kelly A, Contreras-Zarate, Maria Jose, Lai, Steven, Ormond, D Ryan, Rusthoven, Chad G, Gaspar, Laurie E, Rabinovitch, Rachel, Kavanagh, Brian D, Liu, Arthur, Diamond, Jennifer R, Kabos, Peter, Fisher, Christine M

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A phase II clinical trial of the Aurora and angiogenic kinase inhibitor ENMD-2076 for previously treated, advanced, or metastatic triple-negative breast cancer von Diamond, Jennifer R, Eckhardt, S G, Pitts, Todd M, van Bokhoven, Adrie, Aisner, Dara, Gustafson, Daniel L, Capasso, Anna, Sams, Sharon, Kabos, Peter, Zolman, Kathryn, Colvin, Tiffany, Elias, Anthony D, Storniolo, Anna M, Schneider, Bryan P, Gao, Dexiang, Tentler, John J, Borges, Virginia F, Miller, Kathy D

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Genome‐Wide Analysis of miRNA‐mRNA Interactions in Marrow Stromal Cells von Balakrishnan, Ilango, Yang, Xiaodong, Brown, Joseph, Ramakrishnan, Aravind, Torok‐Storb, Beverly, Kabos, Peter, Hesselberth, Jay R., Pillai, Manoj M.

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Patient-derived luminal breast cancer xenografts retain hormone receptor heterogeneity and help define unique estrogen-dependent gene signatures von Kabos, Peter, Finlay-Schultz, Jessica, Li, Chunling, Kline, Enos, Finlayson, Christina, Wisell, Joshua, Manuel, Christopher A., Edgerton, Susan M., Harrell, J. Chuck, Elias, Anthony, Sartorius, Carol A.

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Rare steroid receptor-negative basal-like tumorigenic cells in luminal subtype human breast cancer xenografts von Horwitz, Kathryn B, Dye, Wendy W, Harrell, Joshua Chuck, Kabos, Peter, Sartorius, Carol A

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Abemaciclib in combination with pembrolizumab for HR+, HER2− metastatic breast cancer: Phase 1b study von Rugo, Hope S., Kabos, Peter, Beck, J. Thad, Jerusalem, Guy, Wildiers, Hans, Sevillano, Elena, Paz-Ares, Luis, Chisamore, Michael J., Chapman, Sonya C., Hossain, Anwar M., Chen, Yanyun, Tolaney, Sara M.

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The Six1 oncoprotein downregulates p53 via concomitant regulation of RPL26 and microRNA-27a-3p von Towers, Christina G., Guarnieri, Anna L., Micalizzi, Doug S., Harrell, J. Chuck, Gillen, Austin E., Kim, Jihye, Wang, Chu-An, Oliphant, Michael U.J., Drasin, David J., Guney, Michelle A., Kabos, Peter, Sartorius, Carol A., Tan, Aik-Choon, Perou, Charles M., Espinosa, Joaquin M., Ford, Heide L.

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Expression of Six1 in luminal breast cancers predicts poor prognosis and promotes increases in tumor initiating cells by activation of extracellular signal-regulated kinase and tra... von Iwanaga, Ritsuko, Wang, Chu-An, Micalizzi, Douglas S, Harrell, J Chuck, Jedlicka, Paul, Sartorius, Carol A, Kabos, Peter, Farabaugh, Susan M, Bradford, Andrew P, Ford, Heide L

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Clinical Outcomes for Patients With Metastatic Breast Cancer Treated With Immunotherapy Agents in Phase I Clinical Trials von Schreiber, Anna R., Kagihara, Jodi A., Weiss, Jennifer A., Nicklawsky, Andrew, Gao, Dexiang, Borges, Virginia F., Kabos, Peter, Diamond, Jennifer R.

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Clinical and immune responses to neoadjuvant fulvestrant with or without enzalutamide in ER+/Her2− breast cancer von Elias, Anthony D., Staley, Alyse W., Fornier, Monica, Vidal, Gregory A., Alami, Vida, Sams, Sharon, Spoelstra, Nicole S., Goodspeed, Andrew, Kabos, Peter, Diamond, Jennifer R., Shagisultanova, Elena, Gallagher, Rosa I., Wulfkuhle, Julia D., Petricoin, Emanuel F., Zolman, Kathryn L., McSpadden, Tessa, Jordan, Kimberly R., Slansky, Jill E., Borges, Virginia F., Gao, Dexiang, Richer, Jennifer K.

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Phase II trial of fulvestrant plus enzalutamide in ER+/HER2− advanced breast cancer von Elias, Anthony D., Spoelstra, Nicole S., Staley, Alyse W., Sams, Sharon, Crump, Lyndsey S., Vidal, Gregory A., Borges, Virginia F., Kabos, Peter, Diamond, Jennifer R., Shagisultanova, Elena, Afghahi, Anosheh, Mayordomo, Jose, McSpadden, Tessa, Crawford, Gloria, D’Alessandro, Angelo, Zolman, Kathryn L., van Bokhoven, Adrie, Zhuang, Yonghua, Gallagher, Rosa I., Wulfkuhle, Julia D., Petricoin III, Emanuel F., Gao, Dexiang, Richer, Jennifer K.

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Selective AKT kinase inhibitor capivasertib in combination with fulvestrant in PTEN-mutant ER-positive metastatic breast cancer von Smyth, Lillian M., Batist, Gerald, Meric-Bernstam, Funda, Kabos, Peter, Spanggaard, Iben, Lluch, Ana, Jhaveri, Komal, Varga, Andrea, Wong, Andrea, Schram, Alison M., Ambrose, Helen, Carr, T. Hedley, de Bruin, Elza C., Salinas-Souza, Carolina, Foxley, Andrew, Hauser, Joana, Lindemann, Justin P. O., Maudsley, Rhiannon, McEwen, Robert, Moschetta, Michele, Nikolaou, Myria, Schiavon, Gaia, Razavi, Pedram, Banerji, Udai, Baselga, José, Hyman, David M., Chandarlapaty, Sarat

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Efficacy and Molecular Mechanisms of Differentiated Response to the Aurora and Angiogenic Kinase Inhibitor ENMD-2076 in Preclinical Models of p53-Mutated Triple-Negative Breast Can... von Ionkina, Anastasia A, Tentler, John J, Kim, Jihye, Capasso, Anna, Pitts, Todd M, Ryall, Karen A, Howison, Rebekah R, Kabos, Peter, Sartorius, Carol A, Tan, Aik Choon, Eckhardt, S Gail, Diamond, Jennifer R

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Glioma Tropic Neural Stem Cells Consist of Astrocytic Precursors and Their Migratory Capacity Is Mediated by CXCR4 von Ehtesham, Moneeb, Yuan, Xiangpeng, Kabos, Peter, Chung, Nancy H.C., Liu, Gentao, Akasaki, Yasuharu, Black, Keith L., Yu, John S.

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Abstract 2116: Promoter enrichment of subnucleosomes using breast cancer cell-free DNA von Zukowski, Alexis, Han, Amy, Kabos, Peter, Ramachandran, Srinivas

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ANG1005, a Brain-Penetrating Peptide-Drug Conjugate, Shows Activity in Patients with Breast Cancer with Leptomeningeal Carcinomatosis and Recurrent Brain Metastases von Kumthekar, Priya, Tang, Shou-Ching, Brenner, Andrew J., Kesari, Santosh, Piccioni, David E., Anders, Carey, Carrillo, Jose, Chalasani, Pavani, Kabos, Peter, Puhalla, Shannon, Tkaczuk, Katherine, Garcia, Agustin A., Ahluwalia, Manmeet S., Wefel, Jeffrey S., Lakhani, Nehal, Ibrahim, Nuhad

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Phase I Study of Elacestrant (RAD1901), a Novel Selective Estrogen Receptor Degrader, in ER-Positive, HER2-Negative Advanced Breast Cancer von Bardia, Aditya, Kaklamani, Virginia, Wilks, Sharon, Weise, Amy, Richards, Donald, Harb, Wael, Osborne, Cynthia, Wesolowski, Robert, Karuturi, Meghan, Conkling, Paul, Bagley, Rebecca G., Wang, Yamei, Conlan, Maureen G., Kabos, Peter

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A Phase II Study of Abemaciclib in Patients with Brain Metastases Secondary to Hormone Receptor-Positive Breast Cancer von Tolaney, Sara M., Sahebjam, Solmaz, Le Rhun, Emilie, Bachelot, Thomas, Kabos, Peter, Awada, Ahmad, Yardley, Denise, Chan, Arlene, Conte, Pierfranco, Dieras, Veronique, Lin, Nancy U., Bear, Melissa, Chapman, Sonya C., Yang, Zhengyu, Chen, Yanyun, Anders, Carey K.

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