Antibody resistance of SARS-CoV-2 variants B.1.351 and B.1.1.7 von Wang, Pengfei, Nair, Manoj S., Liu, Lihong, Iketani, Sho, Luo, Yang, Guo, Yicheng, Wang, Maple, Yu, Jian, Zhang, Baoshan, Kwong, Peter D., Graham, Barney S., Mascola, John R., Chang, Jennifer Y., Yin, Michael T., Sobieszczyk, Magdalena, Kyratsous, Christos A., Shapiro, Lawrence, Sheng, Zizhang, Huang, Yaoxing, Ho, David D.

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Structural and Functional Analysis of the D614G SARS-CoV-2 Spike Protein Variant von Yurkovetskiy, Leonid, Wang, Xue, Pascal, Kristen E., Tomkins-Tinch, Christopher, Nyalile, Thomas P., Wang, Yetao, Baum, Alina, Diehl, William E., Dauphin, Ann, Carbone, Claudia, Veinotte, Kristen, Egri, Shawn B., Schaffner, Stephen F., Lemieux, Jacob E., Munro, James B., Rafique, Ashique, Barve, Abhi, Sabeti, Pardis C., Kyratsous, Christos A., Dudkina, Natalya V., Shen, Kuang, Luban, Jeremy

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Antibody cocktail to SARS-CoV-2 spike protein prevents rapid mutational escape seen with individual antibodies von Baum, Alina, Fulton, Benjamin O, Wloga, Elzbieta, Copin, Richard, Pascal, Kristen E, Russo, Vincenzo, Giordano, Stephanie, Lanza, Kathryn, Negron, Nicole, Ni, Min, Wei, Yi, Atwal, Gurinder S, Murphy, Andrew J, Stahl, Neil, Yancopoulos, George D, Kyratsous, Christos A

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SARS-CoV-2 spike therapeutic antibodies in the age of variants von Baum, Alina, Kyratsous, Christos A

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CRISPR-Cas9 In Vivo Gene Editing for Transthyretin Amyloidosis von Gillmore, Julian D, Gane, Ed, Taubel, Jorg, Kao, Justin, Fontana, Marianna, Maitland, Michael L, Seitzer, Jessica, O’Connell, Daniel, Walsh, Kathryn R, Wood, Kristy, Phillips, Jonathan, Xu, Yuanxin, Amaral, Adam, Boyd, Adam P, Cehelsky, Jeffrey E, McKee, Mark D, Schiermeier, Andrew, Harari, Olivier, Murphy, Andrew, Kyratsous, Christos A, Zambrowicz, Brian, Soltys, Randy, Gutstein, David E, Leonard, John, Sepp-Lorenzino, Laura, Lebwohl, David

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COVID-19 vaccine BNT162b1 elicits human antibody and TH1 T cell responses von Sahin, Ugur, Muik, Alexander, Derhovanessian, Evelyna, Vogler, Isabel, Kranz, Lena M., Vormehr, Mathias, Baum, Alina, Pascal, Kristen, Quandt, Jasmin, Maurus, Daniel, Brachtendorf, Sebastian, Lörks, Verena, Sikorski, Julian, Hilker, Rolf, Becker, Dirk, Eller, Ann-Kathrin, Grützner, Jan, Boesler, Carsten, Rosenbaum, Corinna, Kühnle, Marie-Cristine, Luxemburger, Ulrich, Kemmer-Brück, Alexandra, Langer, David, Bexon, Martin, Bolte, Stefanie, Karikó, Katalin, Palanche, Tania, Fischer, Boris, Schultz, Armin, Shi, Pei-Yong, Fontes-Garfias, Camila, Perez, John L., Swanson, Kena A., Loschko, Jakob, Scully, Ingrid L., Cutler, Mark, Kalina, Warren, Kyratsous, Christos A., Cooper, David, Dormitzer, Philip R., Jansen, Kathrin U., Türeci, Özlem

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Suptavumab for the Prevention of Medically Attended Respiratory Syncytial Virus Infection in Preterm Infants von Simões, Eric A F, Forleo-Neto, Eduardo, Geba, Gregory P, Kamal, Mohamed, Yang, Feng, Cicirello, Helen, Houghton, Matthew R, Rideman, Ronald, Zhao, Qiong, Benvin, Sarah L, Hawes, Alicia, Fuller, Erin D, Wloga, Elzbieta, Pizarro, Jose M Novoa, Munoz, Flor M, Rush, Scott A, McLellan, Jason S, Lipsich, Leah, Stahl, Neil, Yancopoulos, George D, Weinreich, David M, Kyratsous, Christos A, Sivapalasingam, Sumathi

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Pre- and postexposure efficacy of fully human antibodies against Spike protein in a novel humanized mouse model of MERS-CoV infection von Pascal, Kristen E, Christopher M. Coleman, Alejandro O. Mujica, Vishal Kamat, Ashok Badithe, Jeanette Fairhurst, Charleen Hunt, John Strein, Alexander Berrebi, Jeanne M. Sisk, Krystal L. Matthews, Robert Babb, Gang Chen, Ka-Man V. Lai, Tammy T. Huang, William Olson, George D. Yancopoulos, Neil Stahl, Matthew B. Frieman, Christos A. Kyratsous

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Alirocumab, a Therapeutic Human Antibody to PCSK9, Does Not Affect CD81 Levels or Hepatitis C Virus Entry and Replication into Hepatocytes von Ramanathan, Aarti, Gusarova, Viktoria, Stahl, Neil, Gurnett-Bander, Anne, Kyratsous, Christos A

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Development of Clinical-Stage Human Monoclonal Antibodies That Treat Advanced Ebola Virus Disease in Nonhuman Primates von Pascal, Kristen E, Dudgeon, Drew, Trefry, John C, Anantpadma, Manu, Sakurai, Yasuteru, Murin, Charles D, Turner, Hannah L, Fairhurst, Jeanette, Torres, Marcela, Rafique, Ashique, Yan, Ying, Badithe, Ashok, Yu, Kevin, Potocky, Terra, Bixler, Sandra L, Chance, Taylor B, Pratt, William D, Rossi, Franco D, Shamblin, Joshua D, Wollen, Suzanne E, Zelko, Justine M, Carrion, Jr, Ricardo, Worwa, Gabriella, Staples, Hilary M, Burakov, Darya, Babb, Robert, Chen, Gang, Martin, Joel, Huang, Tammy T, Erlandson, Karl, Willis, Melissa S, Armstrong, Kimberly, Dreier, Thomas M, Ward, Andrew B, Davey, Robert A, Pitt, Margaret L M, Lipsich, Leah, Mason, Peter, Olson, William, Stahl, Neil, Kyratsous, Christos A

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Fbxw7α- and GSK3-mediated degradation of p100 is a pro-survival mechanism in multiple myeloma von Busino, Luca, Millman, Scott E., Scotto, Luigi, Kyratsous, Christos A., Basrur, Venkatesha, O’Connor, Owen, Hoffmann, Alexander, Elenitoba-Johnson, Kojo S., Pagano, Michele

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Proteogenomic identification of Hepatitis B virus (HBV) genotype-specific HLA-I restricted peptides from HBV-positive patient liver tissues von Srivastava, Mayank, Copin, Richard, Choy, Augustine, Zhou, Anbo, Olsen, Olav, Wolf, Sarah, Shah, Darshit, Rye-Weller, Anna, Chen, Lisa, Chan, Newton, Coppola, Angel, Lanza, Kathryn, Negron, Nicole, Ni, Min, Atwal, Gurinder S, Kyratsous, Christos A, Olson, William, Salzler, Robert

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REGN-COV2 antibodies prevent and treat SARS-CoV-2 infection in rhesus macaques and hamsters von Baum, Alina, Ajithdoss, Dharani, Copin, Richard, Zhou, Anbo, Lanza, Kathryn, Negron, Nicole, Ni, Min, Wei, Yi, Mohammadi, Kusha, Musser, Bret, Atwal, Gurinder S, Oyejide, Adelekan, Goez-Gazi, Yenny, Dutton, John, Clemmons, Elizabeth, Staples, Hilary M, Bartley, Carmen, Klaffke, Benjamin, Alfson, Kendra, Gazi, Michal, Gonzalez, Olga, Dick, Jr, Edward, Carrion, Jr, Ricardo, Pessaint, Laurent, Porto, Maciel, Cook, Anthony, Brown, Renita, Ali, Vaneesha, Greenhouse, Jack, Taylor, Tammy, Andersen, Hanne, Lewis, Mark G, Stahl, Neil, Murphy, Andrew J, Yancopoulos, George D, Kyratsous, Christos A

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Structure of the Inmazeb cocktail and resistance to Ebola virus escape von Rayaprolu, Vamseedhar, Fulton, Benjamin O., Rafique, Ashique, Arturo, Emilia, Williams, Dewight, Hariharan, Chitra, Callaway, Heather, Parvate, Amar, Schendel, Sharon L., Parekh, Diptiben, Hui, Sean, Shaffer, Kelly, Pascal, Kristen E., Wloga, Elzbieta, Giordano, Stephanie, Negron, Nicole, Ni, Min, Copin, Richard, Atwal, Gurinder S., Franklin, Matthew, Boytz, Ruth Mabel, Donahue, Callie, Davey, Robert, Baum, Alina, Kyratsous, Christos A., Saphire, Erica Ollmann

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The monoclonal antibody combination REGEN-COV protects against SARS-CoV-2 mutational escape in preclinical and human studies von Copin, Richard, Baum, Alina, Wloga, Elzbieta, Pascal, Kristen E., Giordano, Stephanie, Fulton, Benjamin O., Zhou, Anbo, Negron, Nicole, Lanza, Kathryn, Chan, Newton, Coppola, Angel, Chiu, Joyce, Ni, Min, Wei, Yi, Atwal, Gurinder S., Hernandez, Annabel Romero, Saotome, Kei, Zhou, Yi, Franklin, Matthew C., Hooper, Andrea T., McCarthy, Shane, Hamon, Sara, Hamilton, Jennifer D., Staples, Hilary M., Alfson, Kendra, Carrion, Ricardo, Ali, Shazia, Norton, Thomas, Somersan-Karakaya, Selin, Sivapalasingam, Sumathi, Herman, Gary A., Weinreich, David M., Lipsich, Leah, Stahl, Neil, Murphy, Andrew J., Yancopoulos, George D., Kyratsous, Christos A.

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CD8+ T Cells and Macrophages Regulate Pathogenesis in a Mouse Model of Middle East Respiratory Syndrome von Coleman, Christopher M, Sisk, Jeanne M, Halasz, Gabor, Zhong, Jixin, Beck, Sarah E, Matthews, Krystal L, Venkataraman, Thiagarajan, Rajagopalan, Sanjay, Kyratsous, Christos A, Frieman, Matthew B

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The Activin/FLRG Pathway Associates with Poor COVID-19 Outcomes in Hospitalized Patients von McAleavy, Megan, Zhang, Qian, Ehmann, Peter J., Xu, Jianing, Wipperman, Matthew F., Ajithdoss, Dharani, Pan, Li, Wakai, Matthew, Simonson, Raphael, Gadi, Abhilash, Oyejide, Adelekan, Hamon, Sara C., Boyapati, Anita, Morton, Lori G., Shavlakadze, Tea, Kyratsous, Christos A., Glass, David J.

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Prophylactic and therapeutic efficacy of mAb treatment against MERS-CoV in common marmosets von de Wit, Emmie, Feldmann, Friederike, Okumura, Atsushi, Horne, Eva, Haddock, Elaine, Saturday, Greg, Scott, Dana, Erlandson, Karl J., Stahl, Neil, Lipsich, Leah, Kyratsous, Christos A., Feldmann, Heinz

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Human Monoclonal Antibody Cocktail for the Treatment or Prophylaxis of Middle East Respiratory Syndrome Coronavirus von Sivapalasingam, Sumathi, Saviolakis, George A, Kulcsar, Kirsten, Nakamura, Aya, Conrad, Thomas, Hassanein, Mohamed, Sumner, Giane, Elango, Chinnasamy, Kamal, Mohamed A, Eng, Simon, Kyratsous, Christos A, Musser, Bret J, Frieman, Matthew, Kantrowitz, Joel, Weinreich, David M, Yancopoulos, George, Stahl, Neil, Lipsich, Leah

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Cell type-selective targeted delivery of a recombinant lysosomal enzyme for enzyme therapies von Baik, Andrew D., Calafati, Philip, Zhang, Xiaoli, Aaron, Nina A., Mehra, Antonia, Moller-Tank, Sven, Miloscio, Lawrence, Praggastis, Maria, Giovannone, Nicholas, Pan, Cheryl, Tang, Yajun, Bridges, Susannah, Mujica, Alejo, Barbounis, Peter, Yanolatos, Jean, Gale, Nicholas, Li, Ning, Kyratsous, Christos A., Schoenherr, Christopher J., Murphy, Andrew J., Economides, Aris N., Cygnar, Katherine D.

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