Acetyl-CoA carboxylase inhibition disrupts metabolic reprogramming during hepatic stellate cell activation von Bates, Jamie, Vijayakumar, Archana, Ghoshal, Sarani, Marchand, Bruno, Yi, Saili, Kornyeyev, Dmytro, Zagorska, Anna, Hollenback, David, Walker, Katie, Liu, Kathy, Pendem, Swetha, Newstrom, David, Brockett, Robert, Mikaelian, Igor, Kusam, Saritha, Ramirez, Ricardo, Lopez, David, Li, Li, Fuchs, Bryan C., Breckenridge, David G.

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Combinations of an acetyl CoA carboxylase inhibitor with hepatic lipid modulating agents do not augment antifibrotic efficacy in preclinical models of NASH and fibrosis von Vijayakumar, Archana, Okesli‐Armlovich, Ayse, Wang, Ting, Olson, Isabel, Seung, Minji, Kusam, Saritha, Hollenback, David, Mahadevan, Sangeetha, Marchand, Bruno, Toteva, Maria, Breckenridge, David G., Trevaskis, James L., Bates, Jamie

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Regulation of IL-10 Gene Expression in Th2 Cells by Jun Proteins von Wang, Zheng-Yu, Sato, Hiroshi, Kusam, Saritha, Sehra, Sarita, Toney, Lisa M, Dent, Alexander L

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Inhibition of Th2 Differentiation and GATA-3 Expression by BCL-6 von Kusam, Saritha, Toney, Lisa M, Sato, Hiroshi, Dent, Alexander L

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Repression of AP-1 Function: A Mechanism for the Regulation of Blimp-1 Expression and B Lymphocyte Differentiation by the B Cell Lymphoma-6 Protooncogene von Vasanwala, Farha H, Kusam, Saritha, Toney, Lisa M, Dent, Alexander L

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Regulation of Th2 Cytokine Expression in NKT Cells: Unconventional Use of Stat6, GATA-3, and NFAT2 von Wang, Zheng-Yu, Kusam, Saritha, Munugalavadla, Veerendra, Kapur, Reuben, Brutkiewicz, Randy R, Dent, Alexander L

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Transcriptional repressor BCL-6 immortalizes germinal center-like B cells in the absence of p53 function von Kusam, Saritha, Vasanwala, Farha H, Dent, Alexander L

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Aberrant Regulation of Hematopoiesis by T Cells in BAZF-Deficient Mice von Broxmeyer, Hal E., Sehra, Sarita, Cooper, Scott, Toney, Lisa M., Kusam, Saritha, Aloor, Jim J., Marchal, Christophe C., Dinauer, Mary C., Dent, Alexander L.

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Insights into the role of Bcl6 in follicular Th cells using a new conditional mutant mouse model von Hollister, Kristin, Kusam, Saritha, Wu, Hao, Clegg, Ninah, Mondal, Arpita, Sawant, Deepali V, Dent, Alexander L

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Phosphorylation and linear ubiquitin direct A20 inhibition of inflammation von Wertz, Ingrid E., Newton, Kim, Seshasayee, Dhaya, Kusam, Saritha, Lam, Cynthia, Zhang, Juan, Popovych, Nataliya, Helgason, Elizabeth, Schoeffler, Allyn, Jeet, Surinder, Ramamoorthi, Nandhini, Kategaya, Lorna, Newman, Robert J., Horikawa, Keisuke, Dugger, Debra, Sandoval, Wendy, Mukund, Susmith, Zindal, Anuradha, Martin, Flavius, Quan, Clifford, Tom, Jeffrey, Fairbrother, Wayne J., Townsend, Michael, Warming, Søren, DeVoss, Jason, Liu, Jinfeng, Dueber, Erin, Caplazi, Patrick, Lee, Wyne P., Goodnow, Christopher C., Balazs, Mercedesz, Yu, Kebing, Kolumam, Ganesh, Dixit, Vishva M.

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FRI-284-A combination of fenofibrate with a liver-targeted acetyl-CoA carboxylase inhibitor enhances efficacy while reversing plasma triglyceride increases in a murine model of NAS... von Bates, Jamie, Vijayakumar, Archana, Hollenback, David, Kusam, Saritha, Burri, Harini, Breckenridge, David G.

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Sensitivity to antitubulin chemotherapeutics is regulated by MCL1 and FBW7 von Wertz, Ingrid E., Kusam, Saritha, Lam, Cynthia, Okamoto, Toru, Sandoval, Wendy, Anderson, Daniel J., Helgason, Elizabeth, Ernst, James A., Eby, Mike, Liu, Jinfeng, Belmont, Lisa D., Kaminker, Joshua S., O’Rourke, Karen M., Pujara, Kanan, Kohli, Pawan Bir, Johnson, Adam R., Chiu, Mark L., Lill, Jennie R., Jackson, Peter K., Fairbrother, Wayne J., Seshagiri, Somasekar, Ludlam, Mary J. C., Leong, Kevin G., Dueber, Erin C., Maecker, Heather, Huang, David C. S., Dixit, Vishva M.

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Ubiquitin Binding to A20 ZnF4 Is Required for Modulation of NF-κB Signaling von Bosanac, Ivan, Wertz, Ingrid E., Pan, Borlan, Yu, Christine, Kusam, Saritha, Lam, Cynthia, Phu, Lilian, Phung, Qui, Maurer, Brigitte, Arnott, David, Kirkpatrick, Donald S., Dixit, Vishva M., Hymowitz, Sarah G.

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Combination of the BET Inhibitor GS-5829 and a BCL2 Inhibitor Resulted in Broader Activity in DLBCL and MCL Cell Lines von Bates, Jamie, Kusam, Saritha, Tannheimer, Stacey, Clarke, Astrid, Kenney, Thomas, Breckenridge, David, Tumas, Daniel

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The Combination of a BET Inhibitor (GS-5829) and a BTK Inhibitor (GS-4059) Potentiates DLBCL Cell Line Cell Death and Reduces Expression of MYC, IL-10, and IL-6 in Vitro von Bates, Jamie, Kusam, Saritha, Tannheimer, Stacey, Chan, Julie, Li, Yvonne, Breckenridge, David, Tumas, Daniel

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Liver-chip: a model for understanding diet-induced liver disease and drug efficacy assessment von Carter, Dwayne, Andriani, Grasiella, Jadalannagari, Sushma, Jeanty, Sauveur, Sauld, John, Joshipura, Sannidhi, Bates, Jamie, Kusam, Saritha, Miranda, Diego, Armlovich, Ayse Okesli, Vijayakumar, Archana, Jang, Kyung-Jin, Hamilton, Geraldine, Karalis, Katia, Trevaskis, James

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SAT015 - Liver-chip: a model for understanding diet-induced liver disease and drug efficacy assessment von Carter, Dwayne, Andriani, Grasiella, Jadalannagari, Sushma, Jeanty, Sauveur, Sauld, John, Joshipura, Sannidhi, Bates, Jamie, Kusam, Saritha, Miranda, Diego, Armlovich, Ayse Okesli, Vijayakumar, Archana, Jang, Kyung-Jin, Hamilton, Geraldine, Karalis, Katia, Trevaskis, James

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Structure-guided discovery of a novel, potent, and orally bioavailable 3,5-dimethylisoxazole aryl-benzimidazole BET bromodomain inhibitor von Sperandio, David, Aktoudianakis, Vangelis, Babaoglu, Kerim, Chen, Xiaowu, Elbel, Kristyna, Chin, Gregory, Corkey, Britton, Du, Jinfa, Jiang, Bob, Kobayashi, Tetsuya, Mackman, Richard, Martinez, Ruben, Yang, Hai, Zablocki, Jeff, Kusam, Saritha, Jordan, Kim, Webb, Heather, Bates, Jamie G., Lad, Latesh, Mish, Michael, Niedziela-Majka, Anita, Metobo, Sammy, Sapre, Annapurna, Hung, Magdeleine, Jin, Debi, Fung, Wanchi, Kan, Elaine, Eisenberg, Gene, Larson, Nate, Newby, Zachary E.R., Lansdon, Eric, Tay, Chin, Neve, Richard M., Shevick, Sophia L., Breckenridge, David G.

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Insights into the Role of Bcl6 in Follicular Helper T Cells Using a New Conditional Mutant Mouse Model von Hollister, Kristin, Kusam, Saritha, Wu, Hao, Clegg, Ninah, Mondal, Arpita, Sawant, Deepali V., Dent, Alexander L.

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BCL6 cooperates with CD40 stimulation and loss of p53 function to rapidly transform primary B cells von Kusam, Saritha, Munugalavadla, Veerendra, Sawant, Deepali, Dent, Alexander

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