Utility of a human FcRn transgenic mouse model in drug discovery for early assessment and prediction of human pharmacokinetics of monoclonal antibodies von Avery, Lindsay B, Wang, Mengmeng, Kavosi, Mania S, Joyce, Alison, Kurz, Jeffrey C, Fan, Yao-Yun, Dowty, Martin E, Zhang, Minlei, Zhang, Yiqun, Cheng, Aili, Hua, Fei, Jones, Hannah M, Neubert, Hendrik, Polzer, Robert J, O'Hara, Denise M

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The Affinity of Magnesium Binding Sites in the Bacillus subtilis RNase P·Pre-tRNA Complex Is Enhanced by the Protein Subunit von Kurz, Jeffrey C, Fierke, Carol A

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Expanding RNAi therapeutics to extrahepatic tissues with lipophilic conjugates von Brown, Kirk M., Nair, Jayaprakash K., Janas, Maja M., Anglero-Rodriguez, Yesseinia I., Dang, Lan T. H., Peng, Haiyan, Theile, Christopher S., Castellanos-Rizaldos, Elena, Brown, Christopher, Foster, Donald, Kurz, Jeffrey, Allen, Jeffrey, Maganti, Rajanikanth, Li, Jing, Matsuda, Shigeo, Stricos, Matthew, Chickering, Tyler, Jung, Michelle, Wassarman, Kelly, Rollins, Jeff, Woods, Lauren, Kelin, Alex, Guenther, Dale C., Mobley, Melissa W., Petrulis, John, McDougall, Robin, Racie, Timothy, Bombardier, Jessica, Cha, Diana, Agarwal, Saket, Johnson, Lei, Jiang, Yongfeng, Lentini, Scott, Gilbert, Jason, Nguyen, Tuyen, Chigas, Samantha, LeBlanc, Sarah, Poreci, Urjana, Kasper, Anne, Rogers, Arlin B., Chong, Saeho, Davis, Wendell, Sutherland, Jessica E., Castoreno, Adam, Milstein, Stuart, Schlegel, Mark K., Zlatev, Ivan, Charisse, Klaus, Keating, Mark, Manoharan, Muthiah, Fitzgerald, Kevin, Wu, Jing-Tao, Maier, Martin A., Jadhav, Vasant

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Ribonuclease P: a ribonucleoprotein enzyme von Kurz, Jeffrey C, Fierke, Carol A

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Pharmacologic and pharmacokinetic assessment of anti-TGFβ2 aptamers in rabbit plasma and aqueous humor von MCCAULEY, Thomas G, KURZ, Jeffrey C, MERLINO, Patricia G, LEWIS, Scott D, GILBERT, Madaline, EPSTEIN, David M, MARSH, H. Nicholas

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Specific phosphorothioate substitutions probe the active site of Bacillus subtilis ribonuclease P von CRARY, SHARON M., KURZ, JEFFREY C., FIERKE, CAROL A.

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The Nonclinical Disposition and Pharmacokinetic/Pharmacodynamic Properties of N -Acetylgalactosamine-Conjugated Small Interfering RNA Are Highly Predictable and Build Confidence in... von McDougall, Robin, Ramsden, Diane, Agarwal, Sagar, Agarwal, Saket, Aluri, Krishna, Arciprete, Michael, Brown, Christopher, Castellanos-Rizaldos, Elena, Charisse, Klaus, Chong, Saeho, Cichocki, Joseph, Fitzgerald, Kevin, Goel, Varun, Gu, Yongli, Guenther, Dale, Habtemariam, Bahru, Jadhav, Vasant, Janas, Maja, Jayaraman, Muthusamy, Kurz, Jeffrey, Li, Jing, Liu, Ju, Liu, Xiumin, Liou, Steven, Maclauchlin, Chris, Maier, Martin, Manoharan, Muthiah, Nair, Jayaprakash K, Robbie, Gabriel, Schmidt, Karyn, Smith, Peter, Theile, Christopher, Vaishnaw, Akshay, Waldron, Scott, Xu, Yuanxin, Zhang, Xuemei, Zlatev, Ivan, Wu, Jing-Tao

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Investigation Into the Mechanism of Action and Binding Site of BAX 499, An Aptamer Against Tissue Factor Pathway Inhibitor von Waters, Emily K., Genga, Ryan M., Thomson, Heather A., Schaub, Robert G., Kurz, Jeffrey C., McGinness, Kathleen E.

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Discovery and Characterization of An Anti-APC Aptamer for Use In Hemophilia von Wagner, Patricia G.M., Schwartz, Michael C., McGinness, Kathleen E., Genga, Ryan M., Kurz, Jeffrey C., Waters, Emily K., Schaub, Robert

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Single-Stranded Oligonucleotide Binding to P-Selectin Inhibits Adhesion of Sickle Red Blood Cells and Leukocytes to Endothelial Cells in Sickle Cell Model Mice: Novel Therapeutics... von Gutsaeva, Diana, Parkerson, James, Schaub, Robert G, Kurz, Jeffrey, Head, Alvin

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Protein Component of Bacillus subtilis RNase P Specifically Enhances the Affinity for Precursor-tRNAAsp von Kurz, Jeffrey C, Niranjanakumari, S, Fierke, Carol A

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Aptamer ARC 19499 mediates a procoagulant hemostatic effect by inhibiting tissue factor pathway inhibitor von WATERS, Emily K, GENGA, Ryan M, SCHWARTZ, Michael C, NELSON, Jennifer A, SCHAUB, Robert G, OLSON, Karen A, KURZ, Jeffrey C, MCGINNESS, Kathleen E

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TFPI Antagonist Aptamer ARC19499 Is a Procoagulant In Vitro and In Vivo von McGinness, Kathleen E., Waters, Emily K., Genga, Ryan M., Olson, Karen A., Nelson, Jennifer A., Kurz, Jeffrey C., Schaub, Robert G.

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An Aptamer Antagonist of Tissue Factor Pathway Inhibitor Improves Coagulation in Hemophilia A and FVIII Antibody-Treated Plasma von Waters, Emily K., Kurz, Jeffrey C., Genga, Ryan, Nelson, Jennifer A, McGinness, Kathleen E., Schaub, Robert G.

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Magnesium Ions Are Required by Bacillus subtilis Ribonuclease P RNA for both Binding and Cleaving Precursor tRNAAsp von Beebe, Jane A, Kurz, Jeffrey C, Fierke, Carol A

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Evaluation of a Novel Anti-P-Selectin Aptamer ARC5690 On Venous Inflammation Following Acute Venous Thrombosis von Diaz, Jose Antonio, Lester, Patrick A, Kurz, Jeffrey C, Wrobleski, Shirley K, Hawley, Angela E, Sigler, Robert E, Wakefield, Thomas W, Schaub, Robert G, Myers, Daniel

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Pharmacologic and Pharmacokinetic Assessment of Anti-TGF beta 2 Aptamers in Rabbit Plasma and Aqueous Humor von McCauley, Thomas G, Kurz, Jeffrey C, Merlino, Patricia G, Lewis, Scott D, Gilbert, Madaline, Epstein, David M, Marsh, HNicholas

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ADP-Specific Sensors Enable Universal Assay of Protein Kinase Activity von Srinivasan, Jayaram, Cload, Sharon T, Hamaguchi, Nobuko, Kurz, Jeffrey, Keene, Sara, Kurz, Markus, Boomer, Ryan M, Blanchard, Jill, Epstein, David, Wilson, Charles, Diener, John L

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Pharmacologic and Pharmacokinetic Assessment of Anti-TGF[beta]2 Aptamers in Rabbit Plasma and Aqueous Humor von McCauley, Thomas G, Kurz, Jeffrey C, Merlino, Patricia G, Lewis, Scott D, Gilbert, Madaline, Epstein, David M, Marsh, H Nicholas

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Complement Binding Aptamers and Anti-C5 Agents Useful in the Treatment of Ocular Disorders von Kurz Jeffrey C, Epstein David

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