Immunomodulatory Activity of Nivolumab in Metastatic Renal Cell Carcinoma von Choueiri, Toni K, Fishman, Mayer N, Escudier, Bernard, McDermott, David F, Drake, Charles G, Kluger, Harriet, Stadler, Walter M, Perez-Gracia, Jose Luis, McNeel, Douglas G, Curti, Brendan, Harrison, Michael R, Plimack, Elizabeth R, Appleman, Leonard, Fong, Lawrence, Albiges, Laurence, Cohen, Lewis, Young, Tina C, Chasalow, Scott D, Ross-Macdonald, Petra, Srivastava, Shivani, Jure-Kunkel, Maria, Kurland, John F, Simon, Jason S, Sznol, Mario

Volltext

Histone Deacetylase Inhibitors Radiosensitize Human Melanoma Cells by Suppressing DNA Repair Activity von MUNSHI, Anupama, KURLAND, John F, NISHIKAWA, Takashi, TANAKA, Toshimitsu, HOBBS, Marvette L, TUCKER, Susan L, ISMAIL, Sheikh, STEVENS, Craig, MEYN, Raymond E

Volltext

Myc-mediated transcriptional repression by recruitment of histone deacetylase von Kurland, John F, Tansey, William P

Volltext

Safety and Efficacy of Durvalumab (MEDI4736), an Anti-Programmed Cell Death Ligand-1 Immune Checkpoint Inhibitor, in Patients With Advanced Urothelial Bladder Cancer von Massard, Christophe, Gordon, Michael S, Sharma, Sunil, Rafii, Saeed, Wainberg, Zev A, Luke, Jason, Curiel, Tyler J, Colon-Otero, Gerardo, Hamid, Omid, Sanborn, Rachel E, O'Donnell, Peter H, Drakaki, Alexandra, Tan, Winston, Kurland, John F, Rebelatto, Marlon C, Jin, Xiaoping, Blake-Haskins, John A, Gupta, Ashok, Segal, Neil H

Volltext

Exposure-Response Analyses of Tremelimumab Monotherapy or in Combination with Durvalumab in Patients with Unresectable Hepatocellular Carcinoma von Song, Xuyang, Kelley, Robin Kate, Khan, Anis A, Standifer, Nathan, Zhou, Diansong, Lim, KyoungSoo, Krishna, Rajesh, Liu, Lu, Wang, Kun, McCoon, Patricia, Negro, Alejandra, He, Philip, Gibbs, Megan, Kurland, John F, Abou-Alfa, Ghassan K

Volltext

Modeling of Proliferating CD4 and CD8 T‐Cell Changes to Tremelimumab Exposure in Patients with Unresectable Hepatocellular Carcinoma von Song, Xuyang, Kelley, Robin Kate, Green, Michelle, Standifer, Nathan, Lim, KyoungSoo, Zhou, Diansong, Dunyak, James, Negro, Alejandra, Kurland, John F., Ren, Song, Khan, Anis A., Gibbs, Megan, Abou‐Alfa, Ghassan K.

Volltext

Translation Inhibitors Sensitize Prostate Cancer Cells to Apoptosis Induced by Tumor Necrosis Factor-related Apoptosis-inducing Ligand (TRAIL) by Activating c-Jun N-terminal Kinase von Sah, Nand K., Munshi, Anupama, Kurland, John F., McDonnell, Timothy J., Su, Bing, Meyn, Raymond E.

Volltext

Plain language summary of the HIMALAYA study: tremelimumab and durvalumab for unresectable hepatocellular carcinoma (liver cancer) von Abou-Alfa, Ghassan K, Lau, George, Kudo, Masatoshi, Chan, Stephen L, Kelley, Robin Kate, Furuse, Junji, Sukeepaisarnjaroen, Wattana, Kang, Yoon Koo, Dao, Tu Van, De Toni, Enrico N, Rimassa, Lorenza, Breder, Valeriy, Vasilyev, Alexander, Heurgué, Alexandra, Tam, Vincent C, Mody, Kabir, Thungappa, Satheesh Chiradoni, Ostapenko, Yurii, Yau, Thomas, Azevedo, Sergio, Varela, María, Cheng, Ann-Lii, Qin, Shukui, Galle, Peter R, Ali, Sajid, Gupta, Charu, Makowsky, Mallory, Kurland, John F, Negro, Alejandra, Sangro, Bruno

Volltext

Plain language summary of the TOPAZ-1 study: durvalumab and chemotherapy for advanced biliary tract cancer von Oh, Do-Youn, He, Aiwu Ruth, Qin, Shukui, Chen, Li-Tzong, Okusaka, Takuji, Vogel, Arndt, Kim, Jin Won, Suksombooncharoen, Thatthan, Lee, Myung Ah, Kitano, Masayuki, Burris, Howard, Bouattour, Mohamed, Tanasanvimon, Suebpong, McNamara, Mairead G, Zaucha, Renata, Avallone, Antonio, Tan, Benjamin, Cundom, Juan, Lee, Choong-Kun, Takahashi, Hidenori, Ikeda, Masafumi, Chen, Jen-Shi, Wang, Julie, Makowsky, Mallory, Rokutanda, Nana, Żotkiewicz, Magdalena, Kurland, John F, Cohen, Gordon, Valle, Juan W

Volltext

Protease inhibitors restore radiation‐induced apoptosis to Bcl‐2‐expressing lymphoma cells von Kurland, John F., Meyn, Raymond E.

Volltext

Phase I–IIa study of BMS-690514, an EGFR, HER-2 and -4 and VEGFR-1 to -3 oral tyrosine kinase inhibitor, in patients with advanced or metastatic solid tumours von Soria, Jean-Charles, Baselga, José, Hanna, Nasser, Laurie, Scott A, Bahleda, Rastislav, Felip, Enriqueta, Calvo, Emiliano, Armand, Jean-Pierre, Shepherd, Frances A, Harbison, Christopher T, Berman, David, Park, Jong-Soon, Zhang, Steven, Vakkalagadda, Blisse, Kurland, John F, Pathak, Ashutosh K, Herbst, Roy S

Volltext

Inhibitory Effect of Ketoconazole on the Pharmacokinetics of a Multireceptor Tyrosine Kinase Inhibitor BMS-690514 in Healthy Participants: Assessing the Mechanism of the Interactio... von Yang, Zheng, Vakkalagadda, Blisse, Shen, Guoxiang, Ahlers, Christoph M., Has, Teresa, Christopher, Lisa J., Kurland, John F., Roongta, Vikram, Masson, Eric, Zhang, Steven

Volltext

The MEK/ERK pathway acts upstream of NF kappa B1 (p50) homodimer activity and Bcl-2 expression in a murine B-cell lymphoma cell line. MEK inhibition restores radiation-induced apop... von Kurland, John F, Voehringer, David W, Meyn, Raymond E

Volltext

Inhibition of constitutively activated nuclear factor-κB radiosensitizes human melanoma cells von Munshi, Anupama, Kurland, John F., Nishikawa, Takashi, Chiao, Paul J., Andreeff, Michael, Meyn, Raymond E.

Volltext

Crashing waves of destruction: the cell cycle and APC(Cdh1) regulation of SCF(Skp2) von Kurland, John F, Tansey, William P

Volltext

Mo1250 PATHOLOGICAL COMPLETE RESPONSE (PCR) TO DURVALUMAB PLUS 5-FLUOROURACIL, LEUCOVORIN, OXALIPLATIN AND DOCETAXEL (FLOT) IN RESECTABLE GASTRIC AND GASTROESOPHAGEAL JUNCTION CANC... von Molena, Daniela, Janjigian, Yelena, Al-Batran, Salah-Eddin, Wainberg, Zev A., Van Cutsem, Eric, Muro, Kei, Hyung, Woo J., Wyrwicz, Lucjan, Oh, Do-Youn, Omori, Takeshi, Moehler, Markus, Garrido, Marcelo, Oliveira, Sulene C., Liberman, Moishe, Oliden, Victor Castro, Bilici, Mehmet, Kurland, John F., Xynos, Ioannis, Mann, Helen, Tabernero, Josep

Volltext

680. P02.06 MATTERHORN PCR BY REGION von Janjigian, Yelena Y, Al-Batran, Salah-Eddin, Wainberg, Zev A, Van Cutsem, Eric, Molena, Daniela, Muro, Kei, Hyung, Woo Jin, Wyrwicz, Lucjan, Oh, Do-Youn, Omori, Takeshi, Moehler, Markus, Garrido, Marcelo, Oliveira, Sulene CS, Liberman, Moishe, Oliden, Victor Castro, Bilici, Mehmet, Kurland, John F, Xynos, Ioannis, Mann, Helen, Tabernero, Josep

Volltext

NF- Kappa B1 (p50) Homodimers Contribute to Transcription of the bcl-2 Oncogene von Kurland, J F, Kodym, R, Story, MD, Spurgers, K B, McDonnell, T J, Meyn, R E

Volltext

Biomarker characterization using mass cytometry in a phase 1 trial of urelumab (BMS-663513) in subjects with advanced solid tumors and relapsed/refractory B-cell non-Hodgkin lympho... von Chester, Cariad, Chang, Serena, Kurland, John F., Sagiv-Barfi, Idit, Czerwinski, Debra, Rajapaksa, Amanda, Waller, Erin, Sadaram, Mohith, Richards, Lori, Cohen, Lewis J., Ahlers, Christoph Matthias, Jure-Kunkel, Maria, Maecker, Holden, Levy, Ronald, Kohrt, Holbrook Edwin

Volltext

Abstract 1281: Exploratory analysis of microRNAs as predictive markers of benefit from cetuximab in metastatic colorectal cancer von Kurland, John F., Horak, Christine E., Whitney, Gena S., Malone, Daniel P., Khambata-Ford, Shirin

Volltext