Transcriptomics and mechanistic elucidation of Alzheimer's disease risk genes in the brain and in vitro models von Martiskainen, Henna, Viswanathan, Jayashree, Nykänen, Niko-Petteri, Kurki, Mitja, Helisalmi, Seppo, Natunen, Teemu, Sarajärvi, Timo, Kurkinen, Kaisa M.A, Pursiheimo, Juha-Pekka, Rauramaa, Tuomas, Alafuzoff, Irina, Jääskeläinen, Juha E, Leinonen, Ville, Soininen, Hilkka, Haapasalo, Annakaisa, Huttunen, Henri J, Hiltunen, Mikko

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Synaptic dysfunction and septin protein family members in neurodegenerative diseases von Marttinen, Mikael, Kurkinen, Kaisa Ma, Soininen, Hilkka, Haapasalo, Annakaisa, Hiltunen, Mikko

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Alzheimer's Disease-Associated Ubiquilin-1 Regulates Presenilin-1 Accumulation and Aggresome Formation von Viswanathan, Jayashree, Haapasalo, Annakaisa, Böttcher, Claudia, Miettinen, Riitta, Kurkinen, Kaisa M.A, Lu, Alice, Thomas, Anne, Maynard, Christa J, Romano, Donna, Hyman, Bradley T, Berezovska, Oksana, Bertram, Lars, Soininen, Hilkka, Dantuma, Nico P, Tanzi, Rudolph E, Hiltunen, Mikko

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High-fat diet increases tau expression in the brain of T2DM and AD mice independently of peripheral metabolic status von Takalo, Mari, Haapasalo, Annakaisa, Martiskainen, Henna, Kurkinen, Kaisa M.A., Koivisto, Henna, Miettinen, Pasi, Khandelwal, Vinoth K.M., Kemppainen, Susanna, Kaminska, Dorota, Mäkinen, Petra, Leinonen, Ville, Pihlajamäki, Jussi, Soininen, Hilkka, Laakso, Markku, Tanila, Heikki, Hiltunen, Mikko

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Relationship between ubiquilin-1 and BACE1 in human Alzheimer's disease and APdE9 transgenic mouse brain and cell-based models von Natunen, Teemu, Takalo, Mari, Kemppainen, Susanna, Leskelä, Stina, Marttinen, Mikael, Kurkinen, Kaisa M.A, Pursiheimo, Juha-Pekka, Sarajärvi, Timo, Viswanathan, Jayashree, Gabbouj, Sami, Solje, Eino, Tahvanainen, Eveliina, Pirttimäki, Tiina, Kurki, Mitja, Paananen, Jussi, Rauramaa, Tuomas, Miettinen, Pasi, Mäkinen, Petra, Leinonen, Ville, Soininen, Hilkka, Airenne, Kari, Tanzi, Rudolph E, Tanila, Heikki, Haapasalo, Annakaisa, Hiltunen, Mikko

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Ubiquilin‑1 Modulates γ‑Secretase-Mediated ε‑Site Cleavage in Neuronal Cells von Viswanathan, Jayashree, Haapasalo, Annakaisa, Kurkinen, Kaisa M. A, Natunen, Teemu, Mäkinen, Petra, Bertram, Lars, Soininen, Hilkka, Tanzi, Rudolph E, Hiltunen, Mikko

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SEPT8 modulates β-amyloidogenic processing of APP by affecting the sorting and accumulation of BACE1 von Kurkinen, Kaisa M A, Marttinen, Mikael, Turner, Laura, Natunen, Teemu, Mäkinen, Petra, Haapalinna, Fanni, Sarajärvi, Timo, Gabbouj, Sami, Kurki, Mitja, Paananen, Jussi, Koivisto, Anne M, Rauramaa, Tuomas, Leinonen, Ville, Tanila, Heikki, Soininen, Hilkka, Lucas, Fiona R, Haapasalo, Annakaisa, Hiltunen, Mikko

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Localization of LRRK2 to membranous and vesicular structures in mammalian brain von Biskup, Saskia, Moore, Darren J., Celsi, Fulvio, Higashi, Shinji, West, Andrew B., Andrabi, Shaida A., Kurkinen, Kaisa, Yu, Seong-Woon, Savitt, Joseph M., Waldvogel, Henry J., Faull, Richard L. M., Emson, Piers C., Torp, Reidun, Ottersen, Ole P., Dawson, Ted M., Dawson, Valina L.

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Itraconazole, a P-Glycoprotein and CYP3A4 Inhibitor, Markedly Raises the Plasma Concentrations and Enhances the Renin-Inhibiting Effect of Aliskiren von Tapaninen, Tuija, Backman, Janne T., Kurkinen, Kaisa J., Neuvonen, Pertti J., Niemi, Mikko

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No significant effect of ABCB1 haplotypes on the pharmacokinetics of fluvastatin, pravastatin, lovastatin, and rosuvastatin von Keskitalo, Jenni E., Kurkinen, Kaisa J., Neuvonen, Mikko, Backman, Janne T., Neuvonen, Pertti J., Niemi, Mikko

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CYP2C8 Activity Recovers within 96 Hours after Gemfibrozil Dosing: Estimation of CYP2C8 Half-Life Using Repaglinide as an in Vivo Probe von Backman, Janne T., Honkalammi, Johanna, Neuvonen, Mikko, Kurkinen, Kaisa J., Tornio, Aleksi, Niemi, Mikko, Neuvonen, Pertti J.

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Rifampicin has a Profound Effect on the Pharmacokinetics of Oral S-Ketamine and Less on Intravenous S-Ketamine von Peltoniemi, Marko A., Saari, Teijo I., Hagelberg, Nora M., Laine, Kari, Kurkinen, Kaisa J., Neuvonen, Pertti J., Olkkola, Klaus T.

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Clarithromycin, a potent inhibitor of CYP3A, greatly increases exposure to oral S-ketamine von Hagelberg, Nora M, Peltoniemi, Marko A, Saari, Teijo I, Kurkinen, Kaisa J, Laine, Kari, Neuvonen, Pertti J, Olkkola, Klaus T

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Regulation of key proteins in Alzheimer’s disease molecular pathogenesis by ubiquilin-1 von Takalo, Mari, Viswanathan, Jayashree, Natunen, Teemu, Kurkinen, Kaisa MA, Tanila, Heikki, Soininen, Hilkka, Tanzi, Rudolph E, Hiltunen, Mikko, Haapasalo, Annakaisa

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Involvement of ubiquilin-1 transcript variants in protein degradation and accumulation von Haapasalo, Annakaisa, Viswanathan, Jayashree, Kurkinen, Kaisa M.A., Bertram, Lars, Soininen, Hilkka, Dantuma, Nico P., Tanzi, Rudolph E., Hiltunen, Mikko

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3rd Annual FinnProt Meeting: From Cells to Systems von Korolainen, Minna A, Corthals, Garry L, Kouvonen, Petri, Kurkinen, Kaisa MA, Nyman, Tuula A

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[γ- 35S]GTP autoradiography allows region-specific detection of muscarinic receptor-dependent G-protein activation in the chick optic tectum von Kurkinen, Kaisa M.A, Koistinaho, Jari, Laitinen, Jarmo T

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SEPT8 modulates β-amyloidogenic processing of APP via affecting the sorting and accumulation of BACE1 von Kurkinen, Kaisa M. A., Marttinen, Mikael, Turner, Laura, Natunen, Teemu, Mäkinen, Petra, Haapalinna, Fanni, Sarajärvi, Timo, Gabbouj, Sami, Kurki, Mitja, Paananen, Jussi, Koivisto, Anne M., Rauramaa, Tuomas, Leinonen, Ville, Tanila, Heikki, Soininen, Hilkka, Lucas, Fiona R., Haapasalo, Annakaisa, Hiltunen, Mikko

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Prevention of NMDA‐induced death of cortical neurons by inhibition of protein kinase Cζ von Koponen, Susanna, Kurkinen, Kaisa, Åkerman, Karl E. O., Rosen, Daria Mochly, Chan, Pak H., Koistinaho, Jari

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P2‐281: Alzheimer's disease‐associated ubiquilin‐1 regulates presenilin‐1 accumulation and aggresome formation von Haapasalo, Annakaisa, Viswanathan, Jayashree, Böttcher, Claudia, Miettinen, Riitta, Kurkinen, Kaisa, Maynard, Christa J., Lu, Alice, Bertram, Lars, Soininen, Hilkka, Tanzi, Rudolph E., Dantuma, Nico P., Hiltunen, Mikko

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