Novel myostatin-specific antibody enhances muscle strength in muscle disease models von Muramatsu, Hiroyasu, Kuramochi, Taichi, Katada, Hitoshi, Ueyama, Atsunori, Ruike, Yoshinao, Ohmine, Ken, Shida-Kawazoe, Meiri, Miyano-Nishizawa, Rie, Shimizu, Yuichiro, Okuda, Momoko, Hori, Yuji, Hayashi, Madoka, Haraya, Kenta, Ban, Nobuhiro, Nonaka, Tatsuya, Honda, Masaki, Kitamura, Hidetomo, Hattori, Kunihiro, Kitazawa, Takehisa, Igawa, Tomoyuki, Kawabe, Yoshiki, Nezu, Junichi

Volltext

Humanization and Simultaneous Optimization of Monoclonal Antibody von Kuramochi, Taichi, Igawa, Tomoyuki, Tsunoda, Hiroyuki, Hattori, Kunihiro

Volltext

Antibody engineering to generate SKY59, a long-acting anti-C5 recycling antibody von Sampei, Zenjiro, Haraya, Kenta, Tachibana, Tatsuhiko, Fukuzawa, Taku, Shida-Kawazoe, Meiri, Gan, Siok Wan, Shimizu, Yuichiro, Ruike, Yoshinao, Feng, Shu, Kuramochi, Taichi, Muraoka, Masaru, Kitazawa, Takehisa, Kawabe, Yoshiki, Igawa, Tomoyuki, Hattori, Kunihiro, Nezu, Junichi

Volltext

Anti-factor IXa/X bispecific antibody ACE910 prevents joint bleeds in a long-term primate model of acquired hemophilia A von Muto, Atsushi, Yoshihashi, Kazutaka, Takeda, Minako, Kitazawa, Takehisa, Soeda, Tetsuhiro, Igawa, Tomoyuki, Sampei, Zenjiro, Kuramochi, Taichi, Sakamoto, Akihisa, Haraya, Kenta, Adachi, Kenji, Kawabe, Yoshiki, Nogami, Keiji, Shima, Midori, Hattori, Kunihiro

Volltext

Engineering the variable region of therapeutic IgG antibodies von Igawa, Tomoyuki, Tsunoda, Hiroyuki, Kuramochi, Taichi, Sampei, Zenjiro, Ishii, Shinya, Hattori, Kunihiro

Volltext

Characterizations of a neutralizing antibody broadly reactive to multiple gluten peptide:HLA-DQ2.5 complexes in the context of celiac disease von Okura, Yuu, Ikawa-Teranishi, Yuri, Mizoroki, Akihiko, Takahashi, Noriyuki, Tsushima, Takashi, Irie, Machiko, Harfuddin, Zulkarnain, Miura-Okuda, Momoko, Ito, Shunsuke, Nakamura, Genki, Takesue, Hiroaki, Ozono, Yui, Nishihara, Masamichi, Yamada, Kenta, Gan, Siok Wan, Hayasaka, Akira, Ishii, Shinya, Wakabayashi, Tetsuya, Muraoka, Masaru, Nagaya, Nishiki, Hino, Hiroshi, Nemoto, Takayuki, Kuramochi, Taichi, Torizawa, Takuya, Shimada, Hideaki, Kitazawa, Takehisa, Okazaki, Makoto, Nezu, Junichi, Sollid, Ludvig M., Igawa, Tomoyuki

Volltext

Cynomolgus monkey model of interleukin‐31‐induced scratching depicts blockade of human interleukin‐31 receptor A by a humanized monoclonal antibody von Oyama, Sohei, Kitamura, Hidetomo, Kuramochi, Taichi, Higuchi, Yoshinobu, Matsushita, Hiroaki, Suzuki, Tsukasa, Goto, Masaaki, Adachi, Hideki, Kasutani, Keiko, Sakamoto, Akihisa, Iwayanagi, Yuki, Kaneko, Akihisa, Nanami, Masahiko, Fujii, Etsuko, Esaki, Keiko, Takashima, Yoshiaki, Shimaoka, Shin, Hattori, Kunihiro, Kawabe, Yoshiki

Volltext

Rapid Generation of Murine Bispecific Antibodies Using FAST-IgTM for Preclinical Screening of HER2/CD3 T-Cell Engagers von Koga, Hikaru, Kuroi, Haruka, Hirano, Rena, Hirayama, Hiroyuki, Nabuchi, Yoshiaki, Kuramochi, Taichi

Volltext

Efficient production of bispecific antibody by FAST-IgTM and its application to NXT007 for the treatment of hemophilia A von Koga, Hikaru, Yamano, Takashi, Betancur, Juan, Nagatomo, Satoko, Ikeda, Yousuke, Yamaguchi, Kazuki, Nabuchi, Yoshiaki, Sato, Kazuki, Teranishi-Ikawa, Yuri, Sato, Motohiko, Hirayama, Hiroyuki, Hayasaka, Akira, Torizawa, Takuya, Haraya, Kenta, Sampei, Zenjiro, Shiraiwa, Hirotake, Kitazawa, Takehisa, Igawa, Tomoyuki, Kuramochi, Taichi

Volltext

Elimination of plasma soluble antigen in cynomolgus monkeys by combining pH-dependent antigen binding and novel Fc engineering von Hori, Yuji, Ohmine, Ken, Katada, Hitoshi, Noguchi, Yuki, Sato, Kazuki, Nambu, Takeru, Adeline, Lam Runyi, Wan, Gan Siok, Haraya, Kenta, Ozeki, Kazuhisa, Nanami, Masahiko, Tachibana, Tatsuhiko, Sampei, Zenjiro, Kuramochi, Taichi, Nezu, Junichi, Hattori, Kunihiro, Igawa, Tomoyuki

Volltext

Comprehensive engineering of a therapeutic neutralizing antibody targeting SARS-CoV-2 spike protein to neutralize escape variants von Kuramochi, Taichi, Gan, Siok Wan, Ho, Adrian W S, Wang, Bei, Kageji, Nagisa, Nambu, Takeru, Iida, Sayaka, Okuda-Miura, Momoko, Chia, Wei Shan, Yeo, Chiew Ying, Chen, Dan, Lee, Wen-Hsin, Ngoh, Eve Zi Xian, Mohd Salleh, Siti Nazihah, Wang, Cheng-I, Igawa, Tomoyuki, Shimada, Hideaki

Volltext

In vitro human helper T-cell assay to screen antibody drug candidates for immunogenicity von Ito, Shunsuke, Ikuno, Tatsuya, Mishima, Masayuki, Yano, Mariko, Hara, Toshiko, Kuramochi, Taichi, Sampei, Zenjiro, Wakabayashi, Tetsuya, Tabo, Mitsuyasu, Chiba, Shuichi, Kubo, Chiyomi

Volltext

Engineering a bispecific antibody with a common light chain: Identification and optimization of an anti-CD3 epsilon and anti-GPC3 bispecific antibody, ERY974 von Shiraiwa, Hirotake, Narita, Atsushi, Kamata-Sakurai, Mika, Ishiguro, Takahiro, Sano, Yuji, Hironiwa, Naoka, Tsushima, Takashi, Segawa, Hiroaki, Tsunenari, Toshiaki, Ikeda, Yosuke, Kayukawa, Yoko, Noguchi, Mizuho, Wakabayashi, Tetsuya, Sakamoto, Akihisa, Konishi, Hiroko, Kuramochi, Taichi, Endo, Mika, Hattori, Kunihiro, Nezu, Junichi, Igawa, Tomoyuki

Volltext

Rapid Generation of Murine Bispecific Antibodies Using FAST-Ig[sup.TM] for Preclinical Screening of HER2/CD3 T-Cell Engagers von Koga, Hikaru, Kuroi, Haruka, Hirano, Rena, Hirayama, Hiroyuki, Nabuchi, Yoshiaki, Kuramochi, Taichi

Volltext

Rapid Generation of Murine Bispecific Antibodies Using FAST-Ig TM for Preclinical Screening of HER2/CD3 T-Cell Engagers von Koga, Hikaru, Kuroi, Haruka, Hirano, Rena, Hirayama, Hiroyuki, Nabuchi, Yoshiaki, Kuramochi, Taichi

Volltext

Novel asymmetrically engineered antibody Fc variant with superior FcγR binding affinity and specificity compared with afucosylated Fc variant von Mimoto, Futa, Igawa, Tomoyuki, Kuramochi, Taichi, Katada, Hitoshi, Kadono, Shojiro, Kamikawa, Takayuki, Shida-Kawazoe, Meiri, Hattori, Kunihiro

Volltext

Efficient production of bispecific antibody by FAST-Ig TM and its application to NXT007 for the treatment of hemophilia A von Koga, Hikaru, Yamano, Takashi, Betancur, Juan, Nagatomo, Satoko, Ikeda, Yousuke, Yamaguchi, Kazuki, Nabuchi, Yoshiaki, Sato, Kazuki, Teranishi-Ikawa, Yuri, Sato, Motohiko, Hirayama, Hiroyuki, Hayasaka, Akira, Torizawa, Takuya, Haraya, Kenta, Sampei, Zenjiro, Shiraiwa, Hirotake, Kitazawa, Takehisa, Igawa, Tomoyuki, Kuramochi, Taichi

Volltext

Development of therapeutic antibodies for the treatment of infection diseases and future aspect von Haraya, Kenta, Gotanda, Keisuke, Shiokawa, Rie, Hoshino, Maiko, Kubo, Chiyomi, Kuramochi, Taichi

Volltext

ANTI-MYOSTATIN ANTIBODIES AND METHODS OF USE von RUIKE, Yoshinao, KURAMOCHI, Taichi

Volltext bestellen

Anti-myostatin antibodies and methods of use von Kuramochi, Taichi, Ruike, Yoshinao

Volltext bestellen