Comprehensive transcriptome analysis of fluid shear stress altered gene expression in renal epithelial cells von Kunnen, Steven J., Malas, Tareq B., Semeins, Cornelis M., Bakker, Astrid D., Peters, Dorien J. M.

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An ensemble learning approach for modeling the systems biology of drug-induced injury von Aguirre-Plans, Joaquim, Piñero, Janet, Souza, Terezinha, Callegaro, Giulia, Kunnen, Steven J, Sanz, Ferran, Fernandez-Fuentes, Narcis, Furlong, Laura I, Guney, Emre, Oliva, Baldo

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Identifying multiscale translational safety biomarkers using a network-based systems approach von Callegaro, Giulia, Schimming, Johannes P., Piñero González, Janet, Kunnen, Steven J., Wijaya, Lukas, Trairatphisan, Panuwat, van den Berk, Linda, Beetsma, Kim, Furlong, Laura I., Sutherland, Jeffrey J., Mollon, Jennifer, Stevens, James L., van de Water, Bob

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Qualitative and quantitative concentration-response modelling of gene co-expression networks to unlock hepatotoxic mechanisms for next generation chemical safety assessment von Kunnen, Steven J, Arnesdotter, Emma, Willenbockel, Christian Tobias, Vinken, Mathieu, van de Water, Bob

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A systems approach reveals species differences in hepatic stress response capacity von Russomanno, Giusy, Sison-Young, Rowena, Livoti, Lucia A, Coghlan, Hannah, Jenkins, Rosalind E, Kunnen, Steven J, Fisher, Ciarán P, Reddyhoff, Dennis, Gardner, Iain, Rehman, Adeeb H, Fenwick, Stephen W, Jones, Andrew R, Vermeil De Conchard, Guy, Simonin, Gilles, Bertheux, Helene, Weaver, Richard J, Johnson, Robert L, Liguori, Michael J, Clausznitzer, Diana, Stevens, James L, Goldring, Christopher E, Copple, Ian M

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The human hepatocyte TXG-MAPr: gene co-expression network modules to support mechanism-based risk assessment von Callegaro, Giulia, Kunnen, Steven J., Trairatphisan, Panuwat, Grosdidier, Solène, Niemeijer, Marije, den Hollander, Wouter, Guney, Emre, Piñero Gonzalez, Janet, Furlong, Laura, Webster, Yue W., Saez-Rodriguez, Julio, Sutherland, Jeffrey J., Mollon, Jennifer, Stevens, James L., van de Water, Bob

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Inhibition of Activin Signaling Slows Progression of Polycystic Kidney Disease von Leonhard, Wouter N, Kunnen, Steven J, Plugge, Anna J, Pasternack, Arja, Jianu, Sebastian B T, Veraar, Kimberley, El Bouazzaoui, Fatiha, Hoogaars, Willem M H, Ten Dijke, Peter, Breuning, Martijn H, De Heer, Emile, Ritvos, Olli, Peters, Dorien J M

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Curcumin inhibits cystogenesis by simultaneous interference of multiple signaling pathways: in vivo evidence from a Pkd1-deletion model von Leonhard, Wouter N, van der Wal, Annemieke, Novalic, Zlata, Kunnen, Steven J, Gansevoort, Ron T, Breuning, Martijn H, de Heer, Emile, Peters, Dorien J M

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Fluid shear stress-induced TGF-β/ALK5 signaling in renal epithelial cells is modulated by MEK1/2 von Kunnen, Steven J., Leonhard, Wouter N., Semeins, Cor, Hawinkels, Lukas J. A. C., Poelma, Christian, ten Dijke, Peter, Bakker, Astrid, Hierck, Beerend P., Peters, Dorien J. M.

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Altered Hippo signalling in polycystic kidney disease von Happé, Hester, van der Wal, Annemieke M, Leonhard, Wouter N, Kunnen, Steven J, Breuning, Martijn H, de Heer, Emile, Peters, Dorien JM

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Application of high-throughput transcriptomics for mechanism-based biological read-across of short-chain carboxylic acid analogues of valproic acid von Vrijenhoek, Nanette G, Wehr, Matthias M, Kunnen, Steven J, Wijaya, Lukas S, Callegaro, Giulia, Moné, Martijn J, Escher, Sylvia E, Van de Water, Bob

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Comparative transcriptomics of shear stress treated Pkd1−/− cells and pre-cystic kidneys reveals pathways involved in early polycystic kidney disease von Kunnen, Steven J., Malas, Tareq B., Formica, Chiara, Leonhard, Wouter N., ’t Hoen, Peter A.C., Peters, Dorien J.M.

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High-Throughput Phenotypic Screening of Kinase Inhibitors to Identify Drug Targets for Polycystic Kidney Disease von Booij, Tijmen H., Bange, Hester, Leonhard, Wouter N., Yan, Kuan, Fokkelman, Michiel, Kunnen, Steven J., Dauwerse, Johannes G., Qin, Yu, van de Water, Bob, van Westen, Gerard J. P., Peters, Dorien J. M., Price, Leo S.

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Application of High-Throughput Transcriptomics for Mechanism-Based Biological Read-Across of Short-Chain Carboxylic Acid Analogues of Valproic Acid von Vrijenhoek, Nanette G, Wehr, Matthias M, Kunnen, Steven J, Wijaya, Lukas S, Callegaro, Giulia, Mone, Ma, Escher, Sylvia E, van de Water, Bob

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Fluid shear stress-induced TGF-[beta]/ALK5 signaling in renal epithelial cells is modulated by MEK1/2 von Kunnen, Steven J, Leonhard, Wouter N, Semeins, Cor, Hawinkels, Lukas J, A, C, Poelma, Christian, Ten Dijke, Peter, Bakker, Astrid, Hierck, Beerend P, Peters, Dorien J, M

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The human hepatocyte TXG-MAPr: gene co-expression network modules to support mechanism-based risk assessment von Callegaro, Giulia, Kunnen, Steven J, Trairatphisan, Panuwat, Grosdidier, Solène, Niemeijer, Marije, den Hollander, Wouter, Guney, Emre, Piñero González, Janet, 1977, Furlong, Laura I., 1971, Webster, Yue W, Saez-Rodriguez, Julio, Sutherland, Jeffrey J, Mollon, Jennifer, Stevens, James L, van de Water, Bob

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An ensemble learning approach for modeling the systems biology of drug-induced injury von Aguirre Plans, Joaquim, 1993, Piñero González, Janet, 1977, Souza, Terezinha, Callegaro, Giulia, Kunnen, Steven J, Sanz, Ferran, Fernández Fuentes, Narcís, Furlong, Laura I., 1971, Guney, Emre, Oliva Miguel, Baldomero

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Identifying multiscale translational safety biomarkers using a network-based systems approach von Callegaro, Giulia, Schimming, Johannes P, Piñero González, Janet, 1977, Kunnen, Steven J, Wijaya, Lukas, Trairatphisan, Panuwat, van den Berk, Linda, Beetsma, Kim, Furlong, Laura I, Sutherland, Jeffrey J, Mollon, Jennifer, Stevens, James L, van de Water, Bob

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Curcumin inhibits cystogenesis by simultaneous interference of multiple signaling pathways: in vivo evidence from a Pkd1-deletion model von LEONHARD, Wouter N, VAN DER WAL, Annemieke, NOVALIC, Zlata, KUNNEN, Steven J, GANSEVOORT, Ron T, BREUNING, Martijn H, DE HEER, Emile, PETERS, Dorien J. M

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Additional file 1 of An ensemble learning approach for modeling the systems biology of drug-induced injury von Aguirre-Plans, Joaquim, Piñero, Janet, Terezinha Souza, Callegaro, Giulia, Kunnen, Steven J., Sanz, Ferran, Fernandez-Fuentes, Narcis, Furlong, Laura I., Guney, Emre, Oliva, Baldo

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