Adaptive resistance to therapeutic PD-1 blockade is associated with upregulation of alternative immune checkpoints von Koyama, Shohei, Akbay, Esra A., Li, Yvonne Y., Herter-Sprie, Grit S., Buczkowski, Kevin A., Richards, William G., Gandhi, Leena, Redig, Amanda J., Rodig, Scott J., Asahina, Hajime, Jones, Robert E., Kulkarni, Meghana M., Kuraguchi, Mari, Palakurthi, Sangeetha, Fecci, Peter E., Johnson, Bruce E., Janne, Pasi A., Engelman, Jeffrey A., Gangadharan, Sidharta P., Costa, Daniel B., Freeman, Gordon J., Bueno, Raphael, Hodi, F. Stephen, Dranoff, Glenn, Wong, Kwok-Kin, Hammerman, Peter S.

Volltext

Digital multiplexed gene expression analysis using the NanoString nCounter system von Kulkarni, Meghana M

Volltext

An Integrative Analysis of the InR/PI3K/Akt Network Identifies the Dynamic Response to Insulin Signaling von Vinayagam, Arunachalam, Kulkarni, Meghana M., Sopko, Richelle, Sun, Xiaoyun, Hu, Yanhui, Nand, Ankita, Villalta, Christians, Moghimi, Ahmadali, Yang, Xuemei, Mohr, Stephanie E., Hong, Pengyu, Asara, John M., Perrimon, Norbert

Volltext

Transcriptional enhancers: Intelligent enhanceosomes or flexible billboards? von Arnosti, David N., Kulkarni, Meghana M.

Volltext

Multiparametric profiling of non-small-cell lung cancers reveals distinct immunophenotypes von Lizotte, Patrick H, Ivanova, Elena V, Awad, Mark M, Jones, Robert E, Keogh, Lauren, Liu, Hongye, Dries, Ruben, Almonte, Christina, Herter-Sprie, Grit S, Santos, Abigail, Feeney, Nora B, Paweletz, Cloud P, Kulkarni, Meghana M, Bass, Adam J, Rustgi, Anil K, Yuan, Guo-Cheng, Kufe, Donald W, Jänne, Pasi A, Hammerman, Peter S, Sholl, Lynette M, Hodi, F Stephen, Richards, William G, Bueno, Raphael, English, Jessie M, Bittinger, Mark A, Wong, Kwok-Kin

Volltext

cis-Regulatory Logic of Short-Range Transcriptional Repression in Drosophila melanogaster von Kulkarni, Meghana M., Arnosti, David N.

Volltext

Information display by transcriptional enhancers von Kulkarni, Meghana M, Arnosti, David N

Volltext

Evidence of off-target effects associated with long dsRNAs in Drosophila melanogaster cell-based assays von Kulkarni, Meghana M, Booker, Matthew, Silver, Serena J, Friedman, Adam, Hong, Pengyu, Perrimon, Norbert, Mathey-Prevot, Bernard

Volltext

Super-size flies von Kulkarni, Meghana M., Perrimon, Norbert

Volltext

Prognostic Significance of Myocardial Fibrosis in Hypertrophic Cardiomyopathy von O'Hanlon, Rory, MD, Grasso, Agata, MD, Roughton, Michael, MSc, Moon, James C., MD, Clark, Susan, RN, Wage, Ricardo, Webb, Jessica, MD, Kulkarni, Meghana, MD, Dawson, Dana, MD, PhD, Sulaibeekh, Leena, MD, Chandrasekaran, Badri, MD, Bucciarelli-Ducci, Chiara, MD, Pasquale, Ferdinando, MD, Cowie, Martin R., MD, McKenna, William J., MD, Sheppard, Mary N., MD, Elliott, Perry M., MD, Pennell, Dudley J., MD, Prasad, Sanjay K., MD

Volltext

Abstract A170: Discovery of a potent and selective ATAD2 inhibitor with antiproliferative activity in breast cancer models von Kulkarni, Meghana M., Winter, Jon, Whalley, David, Dale, ian, Denz, Christopher, Guan, Nin, Bhavsar, Deepa, Zhang, Andrew, Rasmusson, Timothy, Fretland, Adrian, Guichard, Sylvie M.

Volltext

Abstract LB-A20: True small molecule STING agonist generates systemic and potent anti-tumor immunity required for effective cancer immunotherapy von Kulkarni, Meghana M, Dwight, Timothy, Marino, Kristen, Allen, Bryce K, Taimi, Mohammed, Bastos, Cecilia, Lai, Sujen, Koh, Cheryl, Samant, Ramya, Tesar, Bethany, Huang, Huang, Chamberlain, Brian, Rice, James M, Tan, Dazhi, Lin, Zhixiong, Shechter, Sharon, Li, Stella, Sparks, Sam, Soutter, Holly, Swann, Steven, Sherman, Woody, Winter, Christopher

Volltext

Abstract B99: Immune profiling of NSCLC tumors and matching normal lung samples by multicolor flow cytometry von Ivanova, Elena, Jones, Robert E., Awad, Mark M., Bittinger, Mark A., Kulkarni, Meghana M., Koyama, Shohei, Almonte, Christina G., Santos, Abigail A., English, Jessie M., Barlow, Julianne, Richards, William G., Hammerman, Peter S., Rodig, Scott J., Bueno, Raphael, Wong, Kwok-Kin

Volltext

Abstract 1110: Functional genomics reveals genetic dependencies in gastric cancer von Kulkarni, Meghana M., Gurumurthy, Sushma, Schmidt-Kittler, Oleg, Berglund, Jason, Hulton, Christopher H., Wilson, David J., Jakubosky, David, Michaud, Daniel, Jones, Robert E., Sjoblom, Nicole M., McSweeney, Russell, Zhou, Hongwei, Venkatakrishnan, Annapurna, Jensen, Karin J., Zhang, Jingxin, Mankoo, Parminder K., Pollard, Jack, Winter, Christopher, Jänne, Pasi A., Wong, Kwok-Kin, Richon, Victoria M., English, Jessie M., Bittinger, Mark A.

Volltext

Adaptive resistance to therapeutic PD-1 blockade is associated with upregulation of alternative immune checkpoints von Koyama, Shohei, Akbay, Esra A, Li, Yvonne Y, Herter-Sprie, Grit S, Buczkowski, Kevin A, Richards, William G, Gandhi, Leena, Redig, Amanda J, Rodig, Scott J, Asahina, Hajime, Jones, Robert E, Kulkarni, Meghana M, Kuraguchi, Mari, Palakurthi, Sangeetha, Fecci, Peter E, Johnson, Bruce E, Janne, Pasi A, Engelman, Jeffrey A, Gangadharan, Sidharta P, Costa, Daniel B, Freeman, Gordon J, Bueno, Raphael, Hodi, F. Stephen, Dranoff, Glenn, Wong, Kwok-Kin, Hammerman, Peter S

Volltext

Abstract B96: Adaptive resistance to therapeutic PD-1:PD-L1 blockade is mediated by upregulation of the TIM-3 immune checkpoint von Akbay, Esra A., Koyama, Shohei, Li, Yvonne Y., Herter-Sprie, Grit S., Buczkowski, Kevin A., Richards, William G., Gandhi, Leena, Redig, Amanda J., Rodig, Scott J., Asahina, Hajime, Jones, Robert E., Kulkarni, Meghana M., Fecci, Peter E., Johnson, Bruce E., Janne, Pasi A., Engelman, Jeffrey A., Gangadharan, Sidharta P., Costa, Daniel B., Freeman, Gordon J., Bueno, Raphael, Hodi, F. Stephen, Dranoff, Glenn, Wong, Kwok-Kin, Hammerman, Peter S.

Volltext

OXOACRIDINYL ACETIC ACID DERIVATIVES AND METHODS OF USE von SHERMAN, Woody, RICE, James M, KULKARNI, Meghana M, LIN, Zhixiong, MARINO, Kristen A, SHECHTER, Sharon, ALLEN, Bryce K, TAN, Dazhi, CHAMBERLAIN, Brian T, JERNIGAN, III, Finith E

Volltext bestellen

Oxoacridinyl acetic acid derivatives and methods of use von Chamberlain, Brian T, Tan, Dazhi, Rice, James M, Shechter, Sharon, Marino, Kristen A, Lin, Zhixiong, Jernigan, III, Finith E, Allen, Bryce K, Sherman, Woody, Kulkarni, Meghana M

Volltext bestellen

BENZO[B][1,8]NAPHTHYRIDINE ACETIC ACID DERIVATIVES AND METHODS OF USE von HUANG, Huang, SWANN, Steven, NIU, Deqiang, KULKARNI, Meghana M, LIN, Zhixiong, MARINO, Kristen A, ALLEN, Bryce K, SHECHTER, Sharon, CHAMBERLAIN, Brian T, DWIGHT, Timothy A

Volltext bestellen

Oxoacridinyl acetic acid derivatives and methods of use von SHERMAN, Woody, RICE, James M, KULKARNI, Meghana M, LIN, Zhixiong, MARINO, Kristen A, JERNIGAN III, Finith E, SHECHTER, Sharon, ALLEN, Bryce K, TAN, Dazhi, CHAMBERLAIN, Brian T

Volltext bestellen