Triglyceride-rich lipoproteins and high-density lipoprotein cholesterol in patients at high risk of cardiovascular disease: evidence and guidance for management von CHAPMAN, M. John, GINSBERG, Henry N, LESNIK, Philippe, MASANA, Luis, NORDESTGAARD, Borge G, RAY, Kausik K, REINER, Zeljko, TASKINEN, Marja-Riitta, TOKGÖZOGLU, Lale, TYBJAERG-HANSEN, Anne, WATTS, Gerald F, AMARENCO, Pierre, ANDREOTTI, Felicita, BOREN, Jan, CATAPANO, Alberico L, DESCAMPS, Olivier S, FISHER, Edward, KOVANEN, Petri T, ALBERT KUIVENHOVEN, Jan

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COMMD Family Regulates Plasma LDL Levels and Attenuates Atherosclerosis Through Stabilizing the CCC Complex in Endosomal LDLR Trafficking von Fedoseienko, Alina, Wijers, Melinde, Wolters, Justina C, Dekker, Daphne, Smit, Marieke, Huijkman, Nicolette, Kloosterhuis, Niels, Klug, Helene, Schepers, Aloys, van Dijk, Ko Willems, Levels, Johannes H M, Billadeau, Daniel D, Hofker, Marten H, van Deursen, Jan, Westerterp, Marit, Burstein, Ezra, Kuivenhoven, Jan Albert, van de Sluis, Bart

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Proteoglycan 4 regulates macrophage function without altering atherosclerotic lesion formation in a murine bone marrow-specific deletion model von Nahon, Joya E., Hoekstra, Menno, Havik, Stefan R., Van Santbrink, Peter J., Dallinga-Thie, Geesje M., Kuivenhoven, Jan-Albert, Geerling, Janine J., Van Eck, Miranda

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ApoE regulates hematopoietic stem cell proliferation, monocytosis, and monocyte accumulation in atherosclerotic lesions in mice von Murphy, Andrew J, Akhtari, Mani, Tolani, Sonia, Pagler, Tamara, Bijl, Nora, Kuo, Chao-Ling, Wang, Mi, Sanson, Marie, Abramowicz, Sandra, Welch, Carrie, Bochem, Andrea E, Kuivenhoven, Jan Albert, Yvan-Charvet, Laurent, Tall, Alan R

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CCC- and WASH-mediated endosomal sorting of LDLR is required for normal clearance of circulating LDL von Bartuzi, Paulina, Billadeau, Daniel D., Favier, Robert, Rong, Shunxing, Dekker, Daphne, Fedoseienko, Alina, Fieten, Hille, Wijers, Melinde, Levels, Johannes H., Huijkman, Nicolette, Kloosterhuis, Niels, van der Molen, Henk, Brufau, Gemma, Groen, Albert K., Elliott, Alison M., Kuivenhoven, Jan Albert, Plecko, Barbara, Grangl, Gernot, McGaughran, Julie, Horton, Jay D., Burstein, Ezra, Hofker, Marten H., van de Sluis, Bart

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GPR146 Deficiency Protects against Hypercholesterolemia and Atherosclerosis von Yu, Haojie, Rimbert, Antoine, Palmer, Alice E., Toyohara, Takafumi, Xia, Yulei, Xia, Fang, Ferreira, Leonardo M.R., Chen, Zhifen, Chen, Tao, Loaiza, Natalia, Horwitz, Nathaniel Brooks, Kacergis, Michael C., Zhao, Liping, Soukas, Alexander A., Kuivenhoven, Jan Albert, Kathiresan, Sekar, Cowan, Chad A.

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Apolipoprotein A-V, triglycerides and risk of coronary artery disease: the prospective Epic-Norfolk Population Study von Vaessen, Stefan F.C., Schaap, Frank G., Kuivenhoven, Jan-Albert, Groen, Albert K., Hutten, Barbara A., Boekholdt, S. Matthijs, Hattori, Hiroaki, Sandhu, Manjinder S., Bingham, Sheila A., Luben, Robert, Palmen, Jutta A., Wareham, Nicholas J., Humphries, Steve E., Kastelein, John J.P., Talmud, Philippa J., Khaw, Kay-Tee

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The HDL hypothesis: does high-density lipoprotein protect from atherosclerosis? von Vergeer, Menno, Holleboom, Adriaan G., Kastelein, John J.P., Kuivenhoven, Jan Albert

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Genetic Variant of the Scavenger Receptor BI in Humans von Vergeer, Menno, Korporaal, Suzanne J.A, Franssen, Remco, Meurs, Illiana, Out, Ruud, Hovingh, G. Kees, Hoekstra, Menno, Sierts, Jeroen A, Dallinga-Thie, Geesje M, Motazacker, Mohammad Mahdi, Holleboom, Adriaan G, Van Berkel, Theo J.C, Kastelein, John J.P, Van Eck, Miranda, Kuivenhoven, Jan Albert

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Hypercholesterolemia and reduced HDL-C promote hematopoietic stem cell proliferation and monocytosis: Studies in mice and FH children von Tolani, Sonia, Pagler, Tamara A, Murphy, Andrew J, Bochem, Andrea E, Abramowicz, Sandra, Welch, Carrie, Nagareddy, Prabhakara R, Holleran, Steve, Hovingh, G.K, Kuivenhoven, Jan Albert, Tall, Alan R

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Lecithin:cholesterol acyltransferase: symposium on 50 years of biomedical research from its discovery to latest findings von Norum, Kaare R., Remaley, Alan T., Miettinen, Helena E., Strøm, Erik H., Balbo, Bruno E.P., Sampaio, Carlos A.T.L., Wiig, Ingrid, Kuivenhoven, Jan Albert, Calabresi, Laura, Tesmer, John J., Zhou, Mingyue, Ng, Dominic S., Skeie, Bjørn, Karathanasis, Sotirios K., Manthei, Kelly A., Retterstøl, Kjetil

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The P274S Mutation of Lecithin-Cholesterol Acyltransferase (LCAT) and Its Clinical Manifestations in a Large Kindred von Fountoulakis, Nikolaos, Lioudaki, Eirini, Lygerou, Dimitra, Dermitzaki, Eleftheria-Kleio, Papakitsou, Ioanna, Kounali, Vasiliki, Holleboom, Adriaan G., Stratigis, Spyros, Belogianni, Christina, Syngelaki, Paraskevi, Stratakis, Stavros, Evangeliou, Athanasios, Gakiopoulou, Hariklia, Kuivenhoven, Jan Albert, Wevers, Ron, Dafnis, Eugene, Stylianou, Kostas

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Advances in genetics show the need for extending screening strategies for autosomal dominant hypercholesterolaemia von MAHDI MOTAZACKER, Mohammad, PIRRUCCELLO, James, ZELCER, Noam, KATHIRESAN, Sekar, FOUCHIER, Sigrid W, HUIJGEN, Roetand, DO, Ron, GABRIEL, Stacey, PETER, Jorge, ATBERT KUIVENHOVEN, Jan, DEFESCHE, Joep C, KASTELEIN, John J. P, KEES HOVINGH, G

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Use of plasma metabolomics to analyze phenotype-genotype relationships in young hypercholesterolemic females von Zhang, Xiang, Rimbert, Antoine, Balder, Willem, Zwinderman, Aeilko Having, Kuivenhoven, Jan Albert, Dallinga-Thie, Geesje Margaretha, Groen, Albert Kornelis

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eNOS activation by HDL is impaired in genetic CETP deficiency von Gomaraschi, Monica, Ossoli, Alice, Pozzi, Silvia, Nilsson, Peter, Cefalù, Angelo B, Averna, Maurizio, Kuivenhoven, Jan Albert, Hovingh, G Kees, Veglia, Fabrizio, Franceschini, Guido, Calabresi, Laura

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Revealing the role of the endosmal sorting machinery in cholesterol homeostasis von Wijers, Melinde, Fedoseienko, Alina, Wolters, Karin, Dekkers, Daphne, Huijkman, Nicolette, Wilbrink, Sanne, Kloosterhuis, Niels, Burstein, Ezra, Billadeau, Daniel, Kuivenhoven, Jan -Albert, Van De Sluis, Bart

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Chemokine-like receptor 1 deficiency does not affect the development of insulin resistance and nonalcoholic fatty liver disease in mice von Gruben, Nanda, Aparicio Vergara, Marcela, Kloosterhuis, Niels J, van der Molen, Henk, Stoelwinder, Stefan, Youssef, Sameh, de Bruin, Alain, Delsing, Dianne J, Kuivenhoven, Jan Albert, van de Sluis, Bart, Hofker, Marten H, Koonen, Debby P Y

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Heterozygosity for a Loss-of-Function Mutation in GALNT2 Improves Plasma Triglyceride Clearance in Man von Holleboom, Adriaan G., Karlsson, Helen, Lin, Ruei-Shiuan, Beres, Thomas M., Sierts, Jeroen A., Herman, Daniel S., Stroes, Erik S.G., Aerts, Johannes M., Kastelein, John J.P., Motazacker, Mohammad M., Dallinga-Thie, Geesje M., Levels, Johannes H.M., Zwinderman, Aeilko H., Seidman, Jonathan G., Seidman, Christine E., Ljunggren, Stefan, Lefeber, Dirk J., Morava, Eva, Wevers, Ron A., Fritz, Timothy A., Tabak, Lawrence A., Lindahl, Mats, Hovingh, G. Kees, Kuivenhoven, Jan Albert

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Low Detection Rates of Genetic FH in Cohort of Patients With Severe Hypercholesterolemia in the United Arabic Emirates von Rimbert, Antoine, Daggag, Hinda, Lansberg, Peter, Buckley, Adam, Viel, Martijn, Kanninga, Roan, Johansson, Lennart, Dullaart, Robin P F, Sinke, Richard, Al Tikriti, Alia, Kuivenhoven, Jan Albert, Barakat, Maha Taysir

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Taking One Step Back in Familial Hypercholesterolemia von Loaiza, Natalia, Hartgers, Merel, Reeskamp, Laurens, Balder, Jan-Willem, Rimbert, Antoine, Bazioti, Venetia, Wolters, Justina, Winkelmeijer, Maaike, Jansen, Hans, Dallinga-Thie, Geesje, Volta, Andrea, Huijkman, Nicolette, Smit, Marieke, Kloosterhuis, Niels, Koster, Mirjam, F Svendsen, Arthur, van de Sluis, Bart, Hovingh, G Kees, Grefhorst, Aldo, Kuivenhoven, Jan Albert

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