Targeting Chemokine Receptors in HIV : A Status Report von KUHMANN, Shawn E, HARTLEY, Oliver

Volltext

HIV-1 clones resistant to a small molecule CCR5 inhibitor use the inhibitor-bound form of CCR5 for entry von Pugach, Pavel, Marozsan, Andre J, Ketas, Thomas J, Landes, Elissa L, Moore, John P, Kuhmann, Shawn E

Volltext

Generation and properties of a human immunodeficiency virus type 1 isolate resistant to the small molecule CCR5 inhibitor, SCH-417690 (SCH-D) von Marozsan, Andre J., Kuhmann, Shawn E., Morgan, Thomas, Herrera, Carolina, Rivera-Troche, Enid, Xu, Serena, Baroudy, Bahige M., Strizki, Julie, Moore, John P.

Volltext

Genetic and Phenotypic Analyses of Human Immunodeficiency Virus Type 1 Escape from a Small-Molecule CCR5 Inhibitor von KUHMANN, Shawn E, PUGACH, Pavel, KORBER, Bette T, WOLINSKY, Steven M, MOORE, John P, KUNSTMAN, Kevin J, TAYLOR, Joann, STANFIELD, Robyn L, SNYDER, Amy, STRIZKI, Julie M, RILEY, Janice, BAROUDY, Bahige M, WILSON, Ian A

Volltext

HIV-1 Escape from a Small Molecule, CCR5-Specific Entry Inhibitor Does Not Involve CXCR4 Use von Trkola, Alexandra, Kuhmann, Shawn E., Strizki, Julie M., Maxwell, Elizabeth, Ketas, Tom, Morgan, Tom, Pugach, Pavel, Xu, Serena, Wojcik, Lisa, Tagat, Jayaram, Palani, Anandan, Shapiro, Sherry, Clader, John W., McCombie, Stuart, Reyes, Gregory R., Baroudy, Bahige M., Moore, John P.

Volltext

Escape of HIV-1 from a small molecule CCR5 inhibitor is not associated with a fitness loss von Anastassopoulou, Cleo G, Marozsan, Andre J, Matet, Alexandre, Snyder, Amy D, Arts, Eric J, Kuhmann, Shawn E, Moore, John P

Volltext

The prolonged culture of human immunodeficiency virus type 1 in primary lymphocytes increases its sensitivity to neutralization by soluble CD4 von Pugach, Pavel, Kuhmann, Shawn E, Taylor, Joann, Marozsan, Andre J, Snyder, Amy, Ketas, Thomas, Wolinsky, Steven M, Korber, Bette T, Moore, John P

Volltext

Effects of CCR5 and CD4 Cell Surface Concentrations on Infections by Macrophagetropic Isolates of Human Immunodeficiency Virus Type 1 von Platt, E J, Wehrly, K, Kuhmann, S E, Chesebro, B, Kabat, D

Volltext

The Differential Sensitivity of Human and Rhesus Macaque CCR5 to Small-Molecule Inhibitors of Human Immunodeficiency Virus Type 1 Entry Is Explained by a Single Amino Acid Differen... von BILLICK, Erika, SEIBERT, Christoph, SAKMAR, Thomas P, MOORE, John P, KUHMANN, Shawn E, PUGACH, Pavel, KETAS, Tom, TRKOLA, Alexandra, ENDRES, Michael J, MURGOLO, Nicholas J, COATES, Elizabeth, REYES, Gregory R, BAROUDY, Bahige M

Volltext

Cooperation of Multiple CCR5 Coreceptors Is Required for Infections by Human Immunodeficiency Virus Type 1 von Kuhmann, S E, Platt, E J, Kozak, S L, Kabat, D

Volltext

Interaction of small molecule inhibitors of HIV-1 entry with CCR5 von Seibert, Christoph, Ying, Weiwen, Gavrilov, Svetlana, Tsamis, Fotini, Kuhmann, Shawn E., Palani, Anandan, Tagat, Jayaram R., Clader, John W., McCombie, Stuart W., Baroudy, Bahige M., Smith, Steven O., Dragic, Tatjana, Moore, John P., Sakmar, Thomas P.

Volltext

Use of a small molecule CCR5 inhibitor in macaques to treat simian immunodeficiency virus infection or prevent simian-human immunodeficiency virus infection von Veazey, Ronald S, Klasse, Per Johan, Ketas, Thomas J, Reeves, Jacqueline D, Piatak, Jr, Michael, Kunstman, Kevin, Kuhmann, Shawn E, Marx, Preston A, Lifson, Jeffrey D, Dufour, Jason, Mefford, Megan, Pandrea, Ivona, Wolinsky, Steven M, Doms, Robert W, DeMartino, Julie A, Siciliano, Salvatore J, Lyons, Kathy, Springer, Martin S, Moore, John P

Volltext

Cell surface expression of CCR5 and other host factors influence the inhibition of HIV-1 infection of human lymphocytes by CCR5 ligands von Ketas, Thomas J, Kuhmann, Shawn E, Palmer, Ashley, Zurita, Juan, He, Weijing, Ahuja, Sunil K, Klasse, Per Johan, Moore, John P

Volltext

Adaptive Mutations in the V3 Loop of gp120 Enhance Fusogenicity of Human Immunodeficiency Virus Type 1 and Enable Use of a CCR5 Coreceptor That Lacks the Amino-Terminal Sulfated Re... von Platt, E J, Kuhmann, S E, Rose, P P, Kabat, D

Volltext

A Critical Site in the Core of the CCR5 Chemokine Receptor Required for Binding and Infectivity of Human Immunodeficiency Virus Type 1 von Siciliano, Salvatore J., Kuhmann, Shawn E., Weng, Youmin, Madani, Navid, Springer, Martin S., Lineberger, Janet E., Danzeisen, Renee, Miller, Michael D., Kavanaugh, Michael P., DeMartino, Julie A., Kabat, David

Volltext

HIV-1 entry inhibitor entrances von Kuhmann, Shawn E, Moore, John P

Volltext

Frequent Substitution Polymorphisms in African Green Monkey CCR5 Cluster at Critical Sites for Infections by Simian Immunodeficiency Virus SIVagm, Implying Ancient Virus-Host Coevo... von Kuhmann, S E, Madani, N, Diop, O M, Platt, E J, Morvan, J, Müller-Trutwin, M C, Barré-Sinoussi, F, Kabat, D

Volltext

Roles of CD4 and Coreceptors in Binding, Endocytosis, and Proteolysis of gp120 Envelope Glycoproteins Derived from Human Immunodeficiency Virus Type 1 von Kozak, Susan L., Kuhmann, Shawn E., Platt, Emily J., Kabat, David

Volltext

Polymorphisms in the CCR5 genes of African green monkeys and mice implicate specific amino acids in infections by simian and human immunodeficiency viruses von Kuhmann, S E, Platt, E J, Kozak, S L, Kabat, D

Volltext

The Fitness Cost to Human Immunodeficiency Virus Type 1 of Escaping From a Small Molecule CCR5 Inhibitor von Marozsan, Andre J, Matet, Alexandre, Kuhmann, Shawn E, Rivera, Enid, Morgan, Tom, Arts, Eric J, Moore, John P

Volltext