Discovery of a Novel Class of Orally Active Antifungal β-1,3-d-Glucan Synthase Inhibitors von WALKER, Scott S, YIMING XU, NORRIS, Christine, ANTONACCI, Barry, GURNANI, Maya, CACCIAPUOTI, Anthony, MCNICHOLAS, Paul M, WAINHAUS, Samuel, JASON HERR, R, KUANG, Rongze, ASLANIAN, Robert G, TING, Pauline C, TRIANTAFYLLOU, Ilias, BLACK, Todd A, WALDMAN, Michelle F, MENDRICK, Cara, BROWN, Nathaniel, MANN, Paul, CHAU, Andrew, PATEL, Reena, BAUMAN, Nicholas

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SAR studies of pyridazinone derivatives as novel glucan synthase inhibitors von Zhou, Gang, Ting, Pauline C., Aslanian, Robert, Cao, Jianhua, Kim, David W., Kuang, Rongze, Lee, Joe F., Schwerdt, John, Wu, Heping, Jason Herr, R., Zych, Andrew J., Yang, Jinhai, Lam, Sang, Wainhaus, Samuel, Black, Todd A., McNicholas, Paul M., Xu, Yiming, Walker, Scott S.

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Lead optimization of a sulfonylurea-based piperazine pyridazinone series of glucan synthase inhibitors von Zych, Andrew J., Lam, Sang Q., Jenkins, David M., Herr, R. Jason, Ting, Pauline C., Lee, Joe F., Kuang, Rongze, Wu, Heping, Kim, David W., Aslanian, Robert G., Wainhaus, Samuel, Black, Todd A., Cacciapuoti, Anthony, McNicholas, Paul M., Xu, Yiming, Walker, Scott S.

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The optimization of pyridazinone series of glucan synthase inhibitors von Kuang, Rongze, Wu, Heping, Ting, Pauline C., Aslanian, Robert G., Cao, Jianhua, Kim, David W., Lee, Joe F., Schwerdt, John, Zhou, Gang, Jason Herr, R., Zych, Andrew J., Yang, Jinhai, Lam, Sang Q., Jenkins, David M., Sakwa, Samuel A., Wainhaus, Samuel, Black, Todd A., Cacciapuoti, Anthony, McNicholas, Paul M., Xu, Yiming, Walker, Scott S.

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Effects of structure on inhibitory activity in a series of mechanism-based inhibitors of human neutrophil elastase von Dou, Dengfeng, He, Guijia, Kuang, Rongze, Fu, Qingfong, Venkataraman, Radhika, Groutas, William C.

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Structure-Based Design of a General Class of Mechanism-Based Inhibitors of the Serine Proteinases Employing a Novel Amino Acid-Derived Heterocyclic Scaffold von Groutas, William C, Kuang, Rongze, Venkataraman, Radhika, Epp, Jeffrey B, Ruan, Sumei, Prakash, Om

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Discovery of aminoquinazoline derivatives as human A(2A) adenosine receptor antagonists von Zhou, Gang, Aslanian, Robert, Gallo, Gioconda, Khan, Tanweer, Kuang, Rongze, Purakkattle, Biju, De Ruiz, Manuel, Stamford, Andrew, Ting, Pauline, Wu, Heping, Wang, Hongwu, Xiao, Dong, Yu, Tao, Zhang, Yonglian, Mullins, Deborra, Hodgson, Robert

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Inhibition of Escherichia coli by dimethyl fumarate von Wang, Hai-Hong, Sun, Da-Wen, Kuang, Rongze

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Use of the 1,2,5-thiadiazolidin-3-one 1,1 dioxide and isothiazolidin-3-one 1,1 dioxide scaffolds in the design of potent inhibitors of serine proteinases von Kuang, Rongze, Venkataraman, Radhika, Ruan, Sumei, Groutas, William C.

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Discovery of aminoquinazoline derivatives as human A sub(2A) adenosine receptor antagonists von Zhou, Gang, Aslanian, Robert, Gallo, Gioconda, Khan, Tanweer, Kuang, Rongze, Purakkattle, Biju, Ruiz, Manuel De, Stamford, Andrew, Ting, Pauline, Wu, Heping, Wang, Hongwu, Xiao, Dong, Yu, Tao, Zhang, Yonglian, Mullins, Deborra, Hodgson, Robert

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Discovery of oral and inhaled PDE4 inhibitors von Ting, Pauline C., Lee, Joe F., Kuang, Rongze, Cao, Jianhua, Gu, Danlin, Huang, Ying, Liu, Zhidan, Aslanian, Robert G., Feng, Kung-I., Prelusky, Daniel, Lamca, James, House, Aileen, Phillips, Jonathan E., Wang, Peng, Wu, Ping, Lundell, Daniel, Chapman, Richard W., Celly, Chander S.

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Substituted 3-oxo-1,2,5-Thiadiazolidine 1,1-Dioxides: A New Class of Potential Mechanism-Based Inhibitors of Human Leukocyte Elastase and Cathepsin G von Groutas, W.C., Kuang, R.Z., Venkataraman, R.

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PLASMA KALLIKREIN INHIBITORS von BAO, Jianming, KUANG, Rongze, YANG, Song, ZHAO, Zhiqiang, WU, Zhicai, LOMBARDO, Matthew, HICKS, Jacqueline

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A general approach toward the design of mechanism-based inactivators of serine proteinases: inactivation of human leukocyte elastase by a phthalimide derivative von Groutas, William C., Chong, Lee S., Venkataraman, Radhika, Huang, He, Epp, Jeffrey B., Kuang, Rongze

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A General Inhibitor Scaffold for Serine Proteases with a (Chymo)trypsin-Like Fold:  Solution-Phase Construction and Evaluation of the First Series of Libraries of Mechanism-Based I... von Kuang, Rongze, Epp, Jeffrey B, Ruan, Sumei, Yu, Hongyi, Huang, Peng, He, Shu, Tu, Juan, Schechter, Norman M, Turbov, Jane, Froelich, Christopher J, Groutas, William C

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FACTOR XI ACTIVATION INHIBITORS von DEBENHAM, John S, NIZNER, Peter, TATOSIAN, Daniel A, KUANG, Rongze, ALI, Amjad, HICKS, Jacqueline D, GAO, Ying-Duo, YANG, Dexi, HRUZA, Alan, WEI, Lan

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PLASMA KALLIKREIN INHIBITORS von TIAN, Maoqun, HICKS, Jacqueline, D, ZHAO, Zhiqiang, SINZ, Christopher, J, SHARP, Phillip Patrick, SHEARN-NANCE, Galen Paul, LOMBARDO, Matthew, J, BAO, Jianming, KUANG, Rongze, LOPEZ, Jovan Alexander, CHENG, Alan, C, YANG, Song, WU, Zhicai, MERCHANT, Rohan

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FACTOR XI ACTIVATION INHIBITORS von Debenham, John S, Wei, Lan, Ali, Amjad, Yang, Dexi, Tatosian, Daniel A, Gao, Ying-Duo, Hruza, Alan, Kuang, Rongze, HICKS, Jacqueline D, Nizner, Peter

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ADENOSINE A2A AND A2B RECEPTOR DUAL ANTAGONISTS FOR IMMUNO-ONCOLOGY von Swaminathan, Uma, Hennessy, Elisabeth T, Mansoor, Umar Faruk, Wu, Heping, Ye, Yingchun, Kelly, Joseph M, Yu, Younong, Lo, Michael Man-Chu, Cumming, Jared N, Ali, Amjad, DeMong, Duane, Kuang, Rongze, Graham, Thomas H, Moreno, Jesus, De Lera Ruiz, Manuel

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FACTOR XI ACTIVATION INHIBITORS von DEBENHAM, John S, NIZNER, Peter, TATOSIAN, Daniel A, KUANG, Rongze, ALI, Amjad, HICKS, Jacqueline D, GAO, Ying-Duo, YANG, Dexi, HRUZA, Alan, WEI, Lan

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