Paradigms for Precision Medicine in Epichaperome Cancer Therapy von Pillarsetty, Nagavarakishore, Jhaveri, Komal, Taldone, Tony, Caldas-Lopes, Eloisi, Punzalan, Blesida, Joshi, Suhasini, Bolaender, Alexander, Uddin, Mohammad M., Rodina, Anna, Yan, Pengrong, Ku, Anson, Ku, Thomas, Shah, Smit K., Lyashchenko, Serge, Burnazi, Eva, Wang, Tai, Lecomte, Nicolas, Janjigian, Yelena, Younes, Anas, Batlevi, Connie W., Guzman, Monica L., Roboz, Gail J., Koziorowski, Jacek, Zanzonico, Pat, Alpaugh, Mary L., Corben, Adriana, Modi, Shanu, Norton, Larry, Larson, Steven M., Lewis, Jason S., Chiosis, Gabriela, Gerecitano, John F., Dunphy, Mark P.S.

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Molecular targeting of carbonic anhydrase IX in mice with hypoxic HT29 colorectal tumor xenografts von Carlin, Sean, Khan, Nahida, Ku, Thomas, Longo, Valerie A, Larson, Steve M, Smith-Jones, Peter M

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Identification of small molecule inhibitors of the hepatitis C virus RNA-dependent RNA polymerase from a pyrrolidine combinatorial mixture von Burton, George, Ku, Thomas W., Carr, Thomas J., Kiesow, Terry, Sarisky, Robert T., Lin-Goerke, Juili, Baker, Audrey, Earnshaw, David L., Hofmann, Glenn A., Keenan, Richard M., Dhanak, Dashyant

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Studies on acyl pyrrolidine inhibitors of HCV RNA-dependent RNA polymerase to identify a molecule with replicon antiviral activity von Burton, George, Ku, Thomas W., Carr, Thomas J., Kiesow, Terry, Sarisky, Robert T., Lin-Goerke, Juili, Hofmann, Glenn A., Slater, Martin J., Haigh, David, Dhanak, Dashyant, Johnson, Victor K., Parry, Nigel R., Thommes, Pia

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Inhibitors of Pantothenate Kinase: Novel Antibiotics for Staphylococcal Infections von CHOUDHRY, Anthony E, MANDICHAK, Tracy L, RATNAM, Kapila, BROSKEY, John P, EGOLF, Richard W, KINSLAND, Cynthia, BEGLEY, Tadhg P, SEEFELD, Mark A, KU, Thomas W, BROWN, James R, ZALACAIN, Magdalena

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Real-Space Identification of Non-Noble Single Atomic Catalytic Sites within Metal-Coordinated Supramolecular Networks von Schulze Lammers, Bertram, López-Salas, Nieves, Stein Siena, Julya, Mirhosseini, Hossein, Yesilpinar, Damla, Heske, Julian, Kühne, Thomas D., Fuchs, Harald, Antonietti, Markus, Mönig, Harry

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In vivo biodistribution and accumulation of 89Zr in mice von Abou, Diane S., Ku, Thomas, Smith-Jones, Peter M.

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Affinity-based proteomics reveal cancer-specific networks coordinated by Hsp90 von Moulick, Kamalika, Ahn, James H, Zong, Hongliang, Rodina, Anna, Cerchietti, Leandro, Gomes DaGama, Erica M, Caldas-Lopes, Eloisi, Beebe, Kristin, Perna, Fabiana, Hatzi, Katerina, Vu, Ly P, Zhao, Xinyang, Zatorska, Danuta, Taldone, Tony, Smith-Jones, Peter, Alpaugh, Mary, Gross, Steven S, Pillarsetty, Nagavarakishore, Ku, Thomas, Lewis, Jason S, Larson, Steven M, Levine, Ross, Erdjument-Bromage, Hediye, Guzman, Monica L, Nimer, Stephen D, Melnick, Ari, Neckers, Len, Chiosis, Gabriela

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Direct design of a potent non-peptide fibrinogen receptor antagonist based on the structure and conformation of a highly constrained cyclic RGD peptide von Ku, Thomas W, Ali, Fadia E, Barton, Linda S, Bean, John W, Bondinell, William E, Burgess, Joelle L, Callahan, James F, Calvo, Raul R, Chen, Lichong

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Abstract 5444: Development of a noninvasive assay to determine drug concentration in tumor during hsp90 inhibitor therapy von Taldone, Tony, Pillarsetty, Nagavarakishore, Dunphy, Mark PS, Gerecitano, John F., Caldas-Lopes, Eloisi, Beattie, Brad, Peter, Radu I., Kang, Yanlong, Rodina, Anna, Yan, Pengrong, DaGama Gomes, Erica M., Bolaender, Alexander, Pressl, Christina, Punzalan, Blesida, Ku, Anson, Ku, Thomas, Shah, Smit, Uddin, Mohammad, Chen, Mei H., Santos, Elmer, Koziorowski, Jacek, Corben, Adriana, Modi, Shanu, Jhaveri, Komal, Lin, Oscar, Vakiani, Efsevia, Janjigian, Yelena, Zanzonico, Pat, Hudis, Clifford, Larson, Steven M., Lewis, Jason S., Chiosis, Gabriela

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Novel mechanistic insights into arginine deiminase pharmacology suggest 18F-FDG is not suitable to evaluate clinical response in melanoma von Stelter, Lars, Evans, Michael J, Jungbluth, Achim A, Zanzonico, Pat, Ritter, Gerd, Ku, Thomas, Rosenfeld, Eric, Bomalaski, John S, Old, Lloyd, Larson, Steven M

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In vivo biodistribution and accumulation of89 Zr in mice von Abou, Diane S, Ku, Thomas, Smith-Jones, Peter M

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Novel Mechanistic Insights into Arginine Deiminase Pharmacology Suggest 18 F-FDG Is Not Suitable to Evaluate Clinical Response in Melanoma von Stelter, Lars, Evans, Michael J., Jungbluth, Achim A., Zanzonico, Pat, Ritter, Gerd, Ku, Thomas, Rosenfeld, Eric, Bomalaski, John S., Old, Lloyd, Larson, Steven M.

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Novel Mechanistic Insights into Arginine Deiminase Pharmacology Suggest ^sup 18^F-FDG Is Not Suitable to Evaluate Clinical Response in Melanoma von Stelter, Lars, Evans, Michael J, Jungbluth, Achim A, Zanzonico, Pat, Ritter, Gerd, Ku, Thomas, Rosenfeld, Eric, Bomalaski, John S, Old, Lloyd, Larson, Steven M

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Conformational Preferences in a Benzodiazepine Series of Potent Nonpeptide Fibrinogen Receptor Antagonists von Keenan, Richard M, Callahan, James F, Samanen, James M, Bondinell, William E, Calvo, Raul R, Chen, Lichong, DeBrosse, Charles, Eggleston, Drake S, Haltiwanger, R. Curtis, Hwang, Shing Mei, Jakas, Dalia R, Ku, Thomas W, Miller, William H, Newlander, Kenneth A, Nichols, Andrew, Parker, Michael F, Southhall, Linda S, Uzinskas, Irene, Vasko-Moser, Janice A, Venslavsky, Joseph W, Wong, Angela S, Huffman, William F

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Imaging expression of the human somatostatin receptor subtype-2 reporter gene with 68Ga-DOTATOC von Zhang, Hanwen, Moroz, Maxim A, Serganova, Inna, Ku, Thomas, Huang, Ruimin, Vider, Jelena, Maecke, Helmut R, Larson, Steven M, Blasberg, Ronald, Smith-Jones, Peter M

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Imaging Expression of the Human Somatostatin Receptor Subtype-2 Reporter Gene with 68 Ga-DOTATOC von Zhang, Hanwen, Moroz, Maxim A., Serganova, Inna, Ku, Thomas, Huang, Ruimin, Vider, Jelena, Maecke, Helmut R., Larson, Steven M., Blasberg, Ronald, Smith-Jones, Peter M.

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Imaging Expression of the Human Somatostatin Receptor Subtype-2 Reporter Gene with ^sup 68^Ga-DOTATOC von Zhang, Hanwen, Moroz, Maxim A, Serganova, Inna, Ku, Thomas, Huang, Ruimin, Vider, Jelena, Maecke, Helmut R, Larson, Steven M, Blasberg, Ronald, Smith-Jones, Peter M

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Abstract 3029: Biochemical evidence towards the existence of an oncogenic Hsp90 complex von Rodina, Anna, Moulick, Kamalika, Ahn, James, Zong, Hongliang, Cerchietti, Leandro, DaGama, Erica Gomes, Caldas-Lopes, Eloisi, Beebe, Kristin, Perna, Fabiana, Hatzi, Katerina, Vu, Ly, Zhao, Xinyang, Zatorska, Danuta, Taldone, Tony, Smith-Jones, Peter, Alpaugh, Mary, Gross, Steven, Pillarsetty, Nagavarakishore, Ku, Thomas, Lewis, Jason, Larson, Steven, Levine, Ross, Erdjument-Bromage, Hediye, Guzman, Monica, Nimer, Stephen, Melnick, Ari, Neckers, Len, Chiosis, Gabriela

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Abstract 1263: Affinity-based proteomics reveal cancer-specific networks coordinated by Hsp90 von Gomes-DaGama, Erica M., Moulick, Kamalika, Ahn, James H., Zong, Hongliang, Rodina, Anna, Cerchietti, Leandro, Lopes-Vazquez, Maria E. Caldas, Beebe, Kristin, Perna, Fabiana, Katerina, Chatzi, Vu, Ly P., Zhao, Xinyang, Zatorska, Danuta, Taldone, Tony, Smith-Jones, Peter, Alpaugh, Mary, Gross, Steven S., Pillarsetty, Nagavarakishore, Ku, Thomas, Lewis, Jason S., Larson, Steven M., Ross, Levine, Erdjument-Bromage, Hediye, Guzman, Monica L., Nimer, Stephen D., Melnick, Ari M., Neckers, Len, Chiosis, Gabriela

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