Plasma Dihydroceramides Are Diabetes Susceptibility Biomarker Candidates in Mice and Humans von Wigger, Leonore, Cruciani-Guglielmacci, Céline, Nicolas, Anthony, Denom, Jessica, Fernandez, Neïké, Fumeron, Frédéric, Marques-Vidal, Pedro, Ktorza, Alain, Kramer, Werner, Schulte, Anke, Le Stunff, Hervé, Liechti, Robin, Xenarios, Ioannis, Vollenweider, Peter, Waeber, Gérard, Uphues, Ingo, Roussel, Ronan, Magnan, Christophe, Ibberson, Mark, Thorens, Bernard

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Mitochondrial Reactive Oxygen Species Are Obligatory Signals for Glucose-Induced Insulin Secretion von LELOUP, Corinne, TOURREL-CUZIN, Cécile, MAGNAN, Christophe, KARACA, Melis, CASTEL, Julien, CARNEIRO, Lionel, COLOMBANI, Anne-Laure, KTORZA, Alain, CASTEILLA, Louis, PENICAUD, Luc

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Mitochondrial Reactive Oxygen Species Are Required for Hypothalamic Glucose Sensing von Leloup, Corinne, Magnan, Christophe, Benani, Alexandre, Bonnet, Emilie, Alquier, Thierry, Offer, Géraldine, Carriere, Audrey, Périquet, Alain, Fernandez, Yvette, Ktorza, Alain, Casteilla, Louis, Pénicaud, Luc

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Small molecule glucokinase activators disturb lipid homeostasis and induce fatty liver in rodents: a warning for therapeutic applications in humans von De Ceuninck, Frédéric, Kargar, Catherine, Ilic, Catherine, Caliez, Audrey, Rolin, Jean‐Olivier, Umbdenstock, Thierry, Vinson, Cédric, Combettes, Murielle, Fanti, Brant, Harley, Elizabeth, Sadlo, Marjorie, Lefèvre, Anne‐Laure, Broux, Olivier, Wierzbicki, Michel, Fourquez, Jean‐Marie, Perron‐Sierra, Françoise, Kotschy, András, Ktorza, Alain

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Interleukin-7 regulates adipose tissue mass and insulin sensitivity in high-fat diet-fed mice through lymphocyte-dependent and independent mechanisms von Lucas, Stéphanie, Taront, Solenne, Magnan, Christophe, Fauconnier, Laurence, Delacre, Myriam, Macia, Laurence, Delanoye, Anne, Verwaerde, Claudie, Spriet, Corentin, Saule, Pasquine, Goormachtigh, Gautier, Héliot, Laurent, Ktorza, Alain, Movassat, Jamileh, Polakowska, Renata, Auriault, Claude, Poulain-Godefroy, Odile, Di Santo, James, Froguel, Philippe, Wolowczuk, Isabelle

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Insulinotropic agent ID-1101 (4-hydroxyisoleucine) activates insulin signaling in rat von Broca, Christophe, Breil, Vincent, Cruciani-Guglielmacci, Celine, Manteghetti, Michele, Rouault, Christine, Derouet, Michel, Rizkalla, Salwa, Pau, Bernard, Petit, Pierre, Ribes, Gerard, Ktorza, Alain, Gross, Rene, Reach, Gerard, Taouis, Mohammed

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Exploring functional beta-cell heterogeneity in vivo using PSA-NCAM as a specific marker von Karaca, Melis, Castel, Julien, Tourrel-Cuzin, Cécile, Brun, Manuel, Géant, Anne, Dubois, Mathilde, Catesson, Sandra, Rodriguez, Marianne, Luquet, Serge, Cattan, Pierre, Lockhart, Brian, Lang, Jochen, Ktorza, Alain, Magnan, Christophe, Kargar, Catherine

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Psammomys Obesus, a Model for Environment-Gene Interactions in Type 2 Diabetes von KAISER, Nurit, NESHER, Rafael, DONATH, Marc Y, FRAENKEL, Merav, BEHAR, Vered, MAGNAN, Christophe, KTORZA, Alain, CERASI, Erol, LEIBOWITZ, Gil

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Fatty Acid Signaling in the Hypothalamus and the Neural Control of Insulin Secretion von Migrenne, Stéphanie, Cruciani-Guglielmacci, Céline, Kang, Ling, Wang, Ruokun, Rouch, Claude, Lefèvre, Anne-Laure, Ktorza, Alain, Routh, Vanessa H., Levin, Barry E., Magnan, Christophe

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Pathophysiological, genetic and gene expression features of a novel rodent model of the cardio-metabolic syndrome von Wallis, Robert H, Collins, Stephan C, Kaisaki, Pamela J, Argoud, Karène, Wilder, Steven P, Wallace, Karin J, Ria, Massimiliano, Ktorza, Alain, Rorsman, Patrik, Bihoreau, Marie-Thérèse, Gauguier, Dominique

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Lipid environment induces ER stress, TXNIP expression and inflammation in immune cells of individuals with type 2 diabetes von Szpigel, Anaïs, Hainault, Isabelle, Carlier, Aurélie, Venteclef, Nicolas, Batto, Anne-Françoise, Hajduch, Eric, Bernard, Catherine, Ktorza, Alain, Gautier, Jean-François, Ferré, Pascal, Bourron, Olivier, Foufelle, Fabienne

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Design and Synthesis of Imidazoline Derivatives Active on Glucose Homeostasis in a Rat Model of Type II Diabetes. 1. Synthesis and Biological Activities of N-Benzyl-N ‘-(arylalkyl)... von Rondu, Frédéric, Le Bihan, Gaëlle, Wang, Xuan, Lamouri, Aazdine, Touboul, Estera, Dive, Georges, Bellahsene, Tounès, Pfeiffer, Bruno, Renard, Pierre, Guardiola-Lemaitre, Béatrice, Manechez, Dominique, Penicaud, Luc, Ktorza, Alain, Godfroid, Jean-Jacques

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Endocrine pancreas plasticity under physiological and pathological conditions von Bernard-Kargar, C, Ktorza, A

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Structure–Activity Relationship of Azaindole-Based Glucokinase Activators von Paczal, Attila, Bálint, Balázs, Wéber, Csaba, Szabó, Zoltán B, Ondi, Levente, Theret, Isabelle, De Ceuninck, Frédéric, Bernard, Catherine, Ktorza, Alain, Perron-Sierra, Francoise, Kotschy, András

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Anti-diabetic activity of fused PPARγ-SIRT1 ligands with limited body-weight gain by mimicking calorie restriction and decreasing SGK1 expression von Pirat, Celine, Dacquet, Catherine, Leclerc, Veronique, Hennuyer, Nathalie, Beucher-Gaudin, Monique, Zanirato, Ghislaine, Géant, Anne, Staels, Bart, Ktorza, Alain, Farce, Amaury, Caignard, Daniel-Henri, Berthelot, Pascal, Lebegue, Nicolas

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Coordinate Transcriptomic and Metabolomic Effects of the Insulin Sensitizer Rosiglitazone on Fundamental Metabolic Pathways in Liver, Soleus Muscle, and Adipose Tissue in Diabetic... von Guigal-Stephan, Nolwen, Rodriguez, Marianne, Le Bouter, Sabrina, Courtade-Gaïani, Sophie, Xuereb, Laura, de Montrion, Catherine, Croixmarie, Vincent, Umbdenstock, Thierry, Boursier-Neyret, Claire, Lonchampt, Michel, Brun, Manuel, Dacquet, Catherine, Ktorza, Alain, Lockhart, Brian-Paul, Galizzi, Jean-Pierre

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Proteasomal degradation of retinoid X receptor α reprograms transcriptional activity of PPARγ in obese mice and humans von Lefebvre, Bruno, Benomar, Yacir, Guedin, Aurore, Langlois, Audrey, Hennuyer, Nathalie, Dumont, Julie, Bouchaert, Emmanuel, Dacquet, Catherine, Penicaud, Luc, Casteilla, Louis, Pattou, Francois, Ktorza, Alain, Staels, Bart, Lefebvre, Philippe

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The Use of Functional MRI to Study Appetite Control in the CNS von De Silva, Akila, Salem, Victoria, Matthews, Paul M., Dhillo, Waljit S.

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Dynamic Changes in β-Cell Mass and Pancreatic Insulin During the Evolution of Nutrition-Dependent Diabetes in Psammomys obesus von Kaiser, Nurit, Yuli, Michal, Üçkaya, Gökhan, Oprescu, Andrei I., Berthault, Marie-France, Kargar, Catherine, Donath, Marc Y., Cerasi, Erol, Ktorza, Alain

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Molecular phenotyping of multiple mouse strains under metabolic challenge uncovers a role for Elovl2 in glucose-induced insulin secretion von Cruciani-Guglielmacci, Céline, Bellini, Lara, Denom, Jessica, Oshima, Masaya, Fernandez, Neïké, Normandie-Levi, Priscilla, Berney, Xavier P, Kassis, Nadim, Rouch, Claude, Dairou, Julien, Gorman, Tracy, Smith, David M, Marley, Anna, Liechti, Robin, Kuznetsov, Dmitry, Wigger, Leonore, Burdet, Frédéric, Lefèvre, Anne-Laure, Wehrle, Isabelle, Uphues, Ingo, Hildebrandt, Tobias, Rust, Werner, Bernard, Catherine, Ktorza, Alain, Rutter, Guy A, Scharfmann, Raphael, Xenarios, Ioannis, Le Stunff, Hervé, Thorens, Bernard, Magnan, Christophe, Ibberson, Mark

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