Loss of Tankyrase-Mediated Destruction of 3BP2 Is the Underlying Pathogenic Mechanism of Cherubism von Levaot, Noam, Voytyuk, Oleksandr, Dimitriou, Ioannis, Sircoulomb, Fabrice, Chandrakumar, Arun, Deckert, Marcel, Krzyzanowski, Paul M., Scotter, Andrew, Gu, Shengqing, Janmohamed, Salima, Cong, Feng, Simoncic, Paul D., Ueki, Yasuyoshi, La Rose, Jose, Rottapel, Robert

Volltext

Simple, multiplexed, PCR-based barcoding of DNA enables sensitive mutation detection in liquid biopsies using sequencing von Ståhlberg, Anders, Krzyzanowski, Paul M, Jackson, Jennifer B, Egyud, Matthew, Stein, Lincoln, Godfrey, Tony E

Volltext

Simple multiplexed PCR-based barcoding of DNA for ultrasensitive mutation detection by next-generation sequencing von Ståhlberg, Anders, Krzyzanowski, Paul M, Egyud, Matthew, Filges, Stefan, Stein, Lincoln, Godfrey, Tony E

Volltext

In-depth characterization of intratumoral heterogeneity in refractory B-cell non-Hodgkin lymphoma through the lens of a Research Autopsy Program von Isaev, Keren, Liu, Ting, Bakhtiari, Mehran, Tong, Kit, Goswami, Rashmi, Lam, Bernard, Lungu, Ilinca, Krzyzanowski, Paul M, Oza, Amit, Dhani, Neesha, Prica, Anca, Crump, Michael, Kridel, Robert

Volltext

Detection of Circulating Tumor DNA in Plasma: A Potential Biomarker for Esophageal Adenocarcinoma von Egyud, Matthew, Tejani, Mohamedtaki, Pennathur, Arjun, Luketich, James, Sridhar, Praveen, Yamada, Emiko, Ståhlberg, Anders, Filges, Stefan, Krzyzanowski, Paul, Jackson, Jennifer, Kalatskaya, Irina, Jiao, Wei, Nielsen, Gradon, Zhou, Zhongren, Litle, Virginia, Stein, Lincoln, Godfrey, Tony

Volltext

CaPSID: a bioinformatics platform for computational pathogen sequence identification in human genomes and transcriptomes von Borozan, Ivan, Wilson, Shane, Blanchette, Paola, Laflamme, Philippe, Watt, Stuart N, Krzyzanowski, Paul M, Sircoulomb, Fabrice, Rottapel, Robert, Branton, Philip E, Ferretti, Vincent

Volltext

Plasma circulating tumor DNA as a potential tool for disease monitoring in head and neck cancer von Egyud, Matthew, Sridhar, Praveen, Devaiah, Anand, Yamada, Emiko, Saunders, Stefanie, Ståhlberg, Anders, Filges, Stefan, Krzyzanowski, Paul M., Kalatskaya, Irina, Jiao, Wei, Stein, Lincoln D., Jalisi, Scharukh, Godfrey, Tony E.

Volltext

Prospective observational study and serosurvey of SARS-CoV-2 infection in asymptomatic healthcare workers at a Canadian tertiary care center von Ferreira, Victor H, Chruscinski, Andrzej, Kulasingam, Vathany, Pugh, Trevor J, Dus, Tamara, Wouters, Brad, Oza, Amit, Ierullo, Matthew, Ku, Terrance, Majchrzak-Kita, Beata, Humar, Sonika T, Bahinskaya, Ilona, Pinzon, Natalia, Zhang, Jianhua, Heisler, Lawrence E, Krzyzanowski, Paul M, Lam, Bernard, Lungu, Ilinca M, Manase, Dorin, Pace, Krista M, Mashouri, Pouria, Brudno, Michael, Garrels, Michael, Mazzulli, Tony, Cybulsky, Myron, Humar, Atul, Kumar, Deepali

Volltext

Transcription phenotypes of pancreatic cancer are driven by genomic events during tumor evolution von Chan-Seng-Yue, Michelle, Kim, Jaeseung C., Wilson, Gavin W., Ng, Karen, Figueroa, Eugenia Flores, O’Kane, Grainne M., Connor, Ashton A., Denroche, Robert E., Grant, Robert C., McLeod, Jessica, Wilson, Julie M., Jang, Gun Ho, Zhang, Amy, Dodd, Anna, Liang, Sheng-Ben, Borgida, Ayelet, Chadwick, Dianne, Kalimuthu, Sangeetha, Lungu, Ilinca, Bartlett, John M. S., Krzyzanowski, Paul M., Sandhu, Vandana, Tiriac, Hervé, Froeling, Fieke E. M., Karasinska, Joanna M., Topham, James T., Renouf, Daniel J., Schaeffer, David F., Jones, Steven J. M., Marra, Marco A., Laskin, Janessa, Chetty, Runjan, Stein, Lincoln D., Zogopoulos, George, Haibe-Kains, Benjamin, Campbell, Peter J., Tuveson, David A., Knox, Jennifer J., Fischer, Sandra E., Gallinger, Steven, Notta, Faiyaz

Volltext

GATA6 Expression Distinguishes Classical and Basal-like Subtypes in Advanced Pancreatic Cancer von O'Kane, Grainne M, Grünwald, Barbara T, Jang, Gun-Ho, Masoomian, Mehdi, Picardo, Sarah, Grant, Robert C, Denroche, Robert E, Zhang, Amy, Wang, Yifan, Lam, Bernard, Krzyzanowski, Paul M, Lungu, Illinca M, Bartlett, John M S, Peralta, Melanie, Vyas, Foram, Khokha, Rama, Biagi, James, Chadwick, Dianne, Ramotar, Stephanie, Hutchinson, Shawn, Dodd, Anna, Wilson, Julie M, Notta, Faiyaz, Zogopoulos, George, Gallinger, Steven, Knox, Jennifer J, Fischer, Sandra E

Volltext

Genomics-Driven Precision Medicine for Advanced Pancreatic Cancer: Early Results from the COMPASS Trial von Aung, Kyaw L, Fischer, Sandra E, Denroche, Robert E, Jang, Gun-Ho, Dodd, Anna, Creighton, Sean, Southwood, Bernadette, Liang, Sheng-Ben, Chadwick, Dianne, Zhang, Amy, O'Kane, Grainne M, Albaba, Hamzeh, Moura, Shari, Grant, Robert C, Miller, Jessica K, Mbabaali, Faridah, Pasternack, Danielle, Lungu, Ilinca M, Bartlett, John M S, Ghai, Sangeet, Lemire, Mathieu, Holter, Spring, Connor, Ashton A, Moffitt, Richard A, Yeh, Jen Jen, Timms, Lee, Krzyzanowski, Paul M, Dhani, Neesha, Hedley, David, Notta, Faiyaz, Wilson, Julie M, Moore, Malcolm J, Gallinger, Steven, Knox, Jennifer J

Volltext

Cryptic genomic lesions in adverse-risk acute myeloid leukemia identified by integrated whole genome and transcriptome sequencing von Kim, Jaeseung C., Zuzarte, Philip C., Murphy, Tracy, Chan-Seng-Yue, Michelle, Brown, Andrew M. K., Krzyzanowski, Paul M., Smith, Adam C., Notta, Faiyaz, Minden, Mark D., McPherson, John D.

Volltext

Impact of Chemical-Induced Mutational Load Increase on Immune Checkpoint Therapy in Poorly Responsive Murine Tumors von Kuczynski, Elizabeth A, Krueger, Janna, Chow, Annabelle, Xu, Ping, Man, Shan, Sundaravadanam, Yogi, Miller, Jessica K, Krzyzanowski, Paul M, Kerbel, Robert S

Volltext

Correction: GATA6 Expression Distinguishes Classical and Basal-like Subtypes in Advanced Pancreatic Cancer von O'Kane, Grainne M, Grünwald, Barbara T, Jang, Gun-Ho, Masoomian, Mehdi, Picardo, Sarah, Grant, Robert C, Denroche, Robert E, Zhang, Amy, Wang, Yifan, Miller, Jessica K, Lam, Bernard, Krzyzanowski, Paul M, Lungu, Ilinca M, Bartlett, John M S, Peralta, Melanie, Vyas, Foram, Khokha, Rama, Biagi, James, Chadwick, Dianne, Ramotar, Stephanie, Hutchinson, Shawn, Dodd, Anna, Wilson, Julie M, Notta, Faiyaz, Zogopoulos, George, Gallinger, Steven, Knox, Jennifer J, Fischer, Sandra E

Volltext

Combined EsophaCap cytology and MUC2 immunohistochemistry for screening of intestinal metaplasia, dysplasia and carcinoma von Zhou, Zhongren, Kalatskaya, Irina, Russell, Donna, Marcon, Norman, Cirocco, Maria, Krzyzanowski, Paul M, Streutker, Cathy, Liang, Hua, Litle, Virginia R, Godfrey, Tony E, Stein, Lincoln

Volltext

Regional perturbation of gene transcription is associated with intrachromosomal rearrangements and gene fusion transcripts in high grade ovarian cancer von Krzyzanowski, Paul M., Sircoulomb, Fabrice, Yousif, Fouad, Normand, Josee, La Rose, Jose, E. Francis, Kyle, Suarez, Fernando, Beck, Tim, McPherson, John D., Stein, Lincoln D., Rottapel, Robert K.

Volltext

Interrogation of Functional Cell-Surface Markers Identifies CD151 Dependency in High-Grade Serous Ovarian Cancer von Medrano, Mauricio, Communal, Laudine, Brown, Kevin R., Iwanicki, Marcin, Normand, Josee, Paterson, Joshua, Sircoulomb, Fabrice, Krzyzanowski, Paul, Novak, Marian, Doodnauth, Sasha A., Saiz, Fernando Suarez, Cullis, Jane, Al-awar, Rima, Neel, Benjamin G., McPherson, John, Drapkin, Ronny, Ailles, Laurie, Mes-Massons, Anne-Marie, Rottapel, Robert

Volltext

Downregulation of histone H2A and H2B pathways is associated with anthracycline sensitivity in breast cancer von Braunstein, Marsela, Liao, Linda, Lyttle, Nicola, Lobo, Nazleen, Taylor, Karen J, Krzyzanowski, Paul M, Kalatskaya, Irina, Yao, Cindy Q, Stein, Lincoln D, Boutros, Paul C, Twelves, Christopher J, Marcellus, Richard, Bartlett, John M S, Spears, Melanie

Volltext

Essential gene profiles in breast, pancreatic, and ovarian cancer cells von Marcotte, Richard, Brown, Kevin R, Suarez, Fernando, Sayad, Azin, Karamboulas, Konstantina, Krzyzanowski, Paul M, Sircoulomb, Fabrice, Medrano, Mauricio, Fedyshyn, Yaroslav, Koh, Judice L Y, van Dyk, Dewald, Fedyshyn, Bodhana, Luhova, Marianna, Brito, Glauber C, Vizeacoumar, Franco J, Vizeacoumar, Frederick S, Datti, Alessandro, Kasimer, Dahlia, Buzina, Alla, Mero, Patricia, Misquitta, Christine, Normand, Josee, Haider, Maliha, Ketela, Troy, Wrana, Jeffrey L, Rottapel, Robert, Neel, Benjamin G, Moffat, Jason

Volltext

Integration of expressed sequence tag data flanking predicted RNA secondary structures facilitates novel non-coding RNA discovery von Krzyzanowski, Paul M, Price, Feodor D, Muro, Enrique M, Rudnicki, Michael A, Andrade-Navarro, Miguel A

Volltext