Validation and refinement of the revised 2017 European LeukemiaNet genetic risk stratification of acute myeloid leukemia von Herold, Tobias, Rothenberg-Thurley, Maja, Grunwald, Victoria V., Janke, Hanna, Goerlich, Dennis, Sauerland, Maria C., Konstandin, Nikola P., Dufour, Annika, Schneider, Stephanie, Neusser, Michaela, Ksienzyk, Bianka, Greif, Philipp A., Subklewe, Marion, Faldum, Andreas, Bohlander, Stefan K., Braess, Jan, Wörmann, Bernhard, Krug, Utz, Berdel, Wolfgang E., Hiddemann, Wolfgang, Spiekermann, Karsten, Metzeler, Klaus H.

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Spectrum and prognostic relevance of driver gene mutations in acute myeloid leukemia von Metzeler, Klaus H., Herold, Tobias, Rothenberg-Thurley, Maja, Amler, Susanne, Sauerland, Maria C., Görlich, Dennis, Schneider, Stephanie, Konstandin, Nikola P., Dufour, Annika, Bräundl, Kathrin, Ksienzyk, Bianka, Zellmeier, Evelyn, Hartmann, Luise, Greif, Philipp A., Fiegl, Michael, Subklewe, Marion, Bohlander, Stefan K., Krug, Utz, Faldum, Andreas, Berdel, Wolfgang E., Wörmann, Bernhard, Büchner, Thomas, Hiddemann, Wolfgang, Braess, Jan, Spiekermann, Karsten

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Addition of sorafenib versus placebo to standard therapy in patients aged 60 years or younger with newly diagnosed acute myeloid leukaemia (SORAML): a multicentre, phase 2, randomi... von Röllig, Christoph, Dr, Serve, Hubert, Prof, Hüttmann, Andreas, MD, Noppeney, Richard, MD, Müller-Tidow, Carsten, Prof, Krug, Utz, MD, Baldus, Claudia D, Prof, Brandts, Christian H, MD, Kunzmann, Volker, Prof, Einsele, Hermann, Prof, Krämer, Alwin, Prof, Schäfer-Eckart, Kerstin, MD, Neubauer, Andreas, Prof, Burchert, Andreas, Prof, Giagounidis, Aristoteles, MD, Krause, Stefan W, Prof, Mackensen, Andreas, Prof, Aulitzky, Walter, Prof, Herbst, Regina, MD, Hänel, Mathias, MD, Kiani, Alexander, Prof, Frickhofen, Norbert, Prof, Kullmer, Johannes, MD, Kaiser, Ulrich, Prof, Link, Hartmut, Prof, Geer, Thomas, MD, Reichle, Albert, Prof, Junghanß, Christian, Prof, Repp, Roland, Prof, Heits, Frank, MD, Dürk, Heinz, Prof, Hase, Jana, Klut, Ina-Maria, PhD, Illmer, Thomas, MD, Bornhäuser, Martin, Prof, Schaich, Markus, Prof, Parmentier, Stefani, MD, Görner, Martin, MD, Thiede, Christian, Prof, von Bonin, Malte, MD, Schetelig, Johannes, Prof, Kramer, Michael, MSc, Berdel, Wolfgang E, Prof, Ehninger, Gerhard, Prof

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Inherited and Somatic Defects in DDX41 in Myeloid Neoplasms von Polprasert, Chantana, Schulze, Isabell, Sekeres, Mikkael A, Makishima, Hideki, Przychodzen, Bartlomiej, Hosono, Naoko, Singh, Jarnail, Padgett, Richard A, Gu, Xiaorong, Phillips, James G, Clemente, Michael, Parker, Yvonne, Lindner, Daniel, Dienes, Brittney, Jankowsky, Eckhard, Saunthararajah, Yogen, Du, Yang, Oakley, Kevin, Nguyen, Nhu, Mukherjee, Sudipto, Pabst, Caroline, Godley, Lucy A, Churpek, Jane E, Pollyea, Daniel A, Krug, Utz, Berdel, Wolfgang E, Klein, Hans-Ulrich, Dugas, Martin, Shiraishi, Yuichi, Chiba, Kenichi, Tanaka, Hiroko, Miyano, Satoru, Yoshida, Kenichi, Ogawa, Seishi, Müller-Tidow, Carsten, Maciejewski, Jaroslaw P

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Genetics of acute myeloid leukemia in the elderly: mutation spectrum and clinical impact in intensively treated patients aged 75 years or older von Prassek, Victoria V, Rothenberg-Thurley, Maja, Sauerland, Maria C, Herold, Tobias, Janke, Hanna, Ksienzyk, Bianka, Konstandin, Nikola P, Goerlich, Dennis, Krug, Utz, Faldum, Andreas, Berdel, Wolfgang E, Wörmann, Bernhard, Braess, Jan, Schneider, Stephanie, Subklewe, Marion, Bohlander, Stefan K, Hiddemann, Wolfgang, Spiekermann, Karsten, Metzeler, Klaus H

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Sorafenib in Combination With Intensive Chemotherapy in Elderly Patients With Acute Myeloid Leukemia: Results From a Randomized, Placebo-Controlled Trial von SERVE, Hubert, KRUG, Utz, FISCHER, Thomas, GIAGOUNIDIS, Aristoteles, NEUBAUER, Andreas, REICHLE, Albrecht, AULITZKY, Walter, NOPPENEY, Richard, BLAU, Igor, KUNZMANN, Volker, STUHLMANN, Reingard, KRÄMER, Alwin, WAGNER, Ruth, KREUZER, Karl-Anton, BRANDTS, Christian, STEFFEN, Björn, THIEDE, Christian, MÜLLER-TIDOW, Carsten, EHNINGER, Gerhard, BERDEL, Wolfgang E, SAUERLAND, M. Cristina, HEINECKE, Achim, BRUNNBERG, Uta, SCHAICH, Markus, OTTMANN, Oliver, DUYSTER, Justus, WANDT, Hannes

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Sorafenib or placebo in patients with newly diagnosed acute myeloid leukaemia: long-term follow-up of the randomized controlled SORAML trial von Röllig, Christoph, Serve, Hubert, Noppeney, Richard, Hanoun, Maher, Krug, Utz, Baldus, Claudia D., Brandts, Christian H., Kunzmann, Volker, Einsele, Hermann, Krämer, Alwin, Müller-Tidow, Carsten, Schäfer-Eckart, Kerstin, Neubauer, Andreas, Burchert, Andreas, Giagounidis, Aristoteles, Krause, Stefan W., Mackensen, Andreas, Aulitzky, Walter, Herbst, Regina, Hänel, Mathias, Frickhofen, Norbert, Kullmer, Johannes, Kaiser, Ulrich, Kiani, Alexander, Link, Hartmut, Geer, Thomas, Reichle, Albrecht, Junghanß, Christian, Repp, Roland, Meinhardt, Achim, Dürk, Heinz, Klut, Ina-Maria, Bornhäuser, Martin, Schaich, Markus, Parmentier, Stefani, Görner, Martin, Thiede, Christian, von Bonin, Malte, Platzbecker, Uwe, Schetelig, Johannes, Kramer, Michael, Berdel, Wolfgang E., Ehninger, Gerhard

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Complete remission and early death after intensive chemotherapy in patients aged 60 years or older with acute myeloid leukaemia: a web-based application for prediction of outcomes von Krug, Utz, Dr, Röllig, Christoph, MD, Koschmieder, Anja, Heinecke, Achim, PhD, Sauerland, Maria Cristina, MSc, Schaich, Markus, Prof, Thiede, Christian, Prof, Kramer, Michael, Braess, Jan, Prof, Spiekermann, Karsten, MD, Haferlach, Torsten, Prof, Haferlach, Claudia, MD, Koschmieder, Steffen, MD, Rohde, Christian, PhD, Serve, Hubert, Prof, Wörmann, Bernhard, Prof, Hiddemann, Wolfgang, Prof, Ehninger, Gerhard, Prof, Berdel, Wolfgang E, Prof, Büchner, Thomas, Prof, Müller-Tidow, Carsten, Prof

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Prediction of complete remission and survival in acute myeloid leukemia using supervised machine learning von Eckardt, Jan-Niklas, Röllig, Christoph, Metzeler, Klaus, Kramer, Michael, Stasik, Sebastian, Georgi, Julia-Annabell, Heisig, Peter, Spiekermann, Karsten, Krug, Utz, Braess, Jan, Görlich, Dennis, Sauerland, Cristina M, Woermann, Bernhard, Herold, Tobias, Berdel, Wolfgang E, Hiddemann, Wolfgang, Kroschinsky, Frank, Schetelig, Johannes, Platzbecker, Uwe, Müller-Tidow, Carsten, Sauer, Tim, Serve, Hubert, Baldus, Claudia, Schäfer-Eckart, Kerstin, Kaufmann, Martin, Krause, Stefan, Hänel, Mathias, Schliemann, Christoph, Hanoun, Maher, Thiede, Christian, Bornhäuser, Martin, Wendt, Karsten, Middeke, Jan Moritz

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Acute Myeloid Leukemia (AML): Different Treatment Strategies Versus a Common Standard Arm—Combined Prospective Analysis by the German AML Intergroup von BÜCHNER, Thomas, SCHLENK, Richard F, SPÄTH, Daniela, KRAMER, Michael, SCHOLL, Sebastian, BERDEL, Wolfgang E, HIDDEMANN, Wolfgang, HOELZER, Dieter, HEHLMANN, Rüdiger, HASFORD, Joerg, HOFFMANN, Verena S, DÖHNER, Hartmut, SCHAICH, Markus, EHNINGER, Gerhard, GANSER, Arnold, NIEDERWIESER, Dietger W, PFIRRMANN, Markus, DÖHNER, Konstanze, KRAHL, Rainer, KRAUTER, Jürgen, HEIL, Gerhard, KRUG, Utz, SAUERLAND, Maria Cristina, HEINECKE, Achim

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Differential diagnosis of Guillain-Barré syndrome: steroid-responsive radiculopathy in Evans syndrome von Schulten, Thomas, Meyer, Ansgar, Krug, Utz, Lehmann, Helmar C

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The neuropeptide receptor calcitonin receptor-like (CALCRL) is a potential therapeutic target in acute myeloid leukemia von Angenendt, Linus, Bormann, Eike, Pabst, Caroline, Alla, Vijay, Görlich, Dennis, Braun, Leonie, Dohlich, Kim, Schwöppe, Christian, Bohlander, Stefan K., Arteaga, Maria Francisca, Wethmar, Klaus, Hartmann, Wolfgang, Angenendt, Adrian, Kessler, Torsten, Mesters, Rolf M., Stelljes, Matthias, Rothenberg-Thurley, Maja, Spiekermann, Karsten, Hébert, Josée, Sauvageau, Guy, Valk, Peter J. M., Löwenberg, Bob, Serve, Hubert, Müller-Tidow, Carsten, Lenz, Georg, Wörmann, Bernhard J., Sauerland, M. Christina, Hiddemann, Wolfgang, Berdel, Wolfgang E., Krug, Utz, Metzeler, Klaus H., Mikesch, Jan-Henrik, Herold, Tobias, Schliemann, Christoph

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Combined molecular and clinical prognostic index for relapse and survival in cytogenetically normal acute myeloid leukemia von Pastore, Friederike, Dufour, Annika, Benthaus, Tobias, Metzeler, Klaus H, Maharry, Kati S, Schneider, Stephanie, Ksienzyk, Bianka, Mellert, Gudrun, Zellmeier, Evelyn, Kakadia, Purvi M, Unterhalt, Michael, Feuring-Buske, Michaela, Buske, Christian, Braess, Jan, Sauerland, Maria Cristina, Heinecke, Achim, Krug, Utz, Berdel, Wolfgang E, Buechner, Thomas, Woermann, Bernhard, Hiddemann, Wolfgang, Bohlander, Stefan K, Marcucci, Guido, Spiekermann, Karsten, Bloomfield, Clara D, Hoster, Eva

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Allogeneic Transplantation Versus Chemotherapy as Postremission Therapy for Acute Myeloid Leukemia: A Prospective Matched Pairs Analysis von STELLJES, Matthias, KRUG, Utz, BERNING, Björna, KOLB, Hans J, REICHLE, Albrecht, HOLLER, Ernst, SCHWERDTFEGER, Rainer, ARNOLD, Renate, SCHEID, Christoph, MÜLLER-TIDOW, Carsten, WOERMANN, Bernhard J, HIDDEMANN, Wolfgang, BEELEN, Dietrich W, BERDEL, Wolfgang E, BÜCHNER, Thomas, BRAESS, Jan, SAUERLAND, Maria C, HEINECKE, Achim, LIGGES, Sandra, SAUER, Tim, TSCHANTER, Petra, THOENNISSEN, Gabriela B

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C/EBPε mediates nicotinamide-enhanced clearance of Staphylococcus aureus in mice von Kyme, Pierre, Thoennissen, Nils H, Tseng, Ching Wen, Thoennissen, Gabriela B, Wolf, Andrea J, Shimada, Kenichi, Krug, Utz O, Lee, Kunik, Müller-Tidow, Carsten, Berdel, Wolfgang E, Hardy, W David, Gombart, Adrian F, Koeffler, H Phillip, Liu, George Y

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Prevalence and prognostic impact of allelic imbalances associated with leukemic transformation of Philadelphia chromosome–negative myeloproliferative neoplasms von Thoennissen, Nils H., Krug, Utz O., Lee, Dhong Hyun Tony, Kawamata, Norihiko, Iwanski, Gabriela B., Lasho, Terra, Weiss, Tamara, Nowak, Daniel, Koren-Michowitz, Maya, Kato, Motohiro, Sanada, Masashi, Shih, Lee-Yung, Nagler, Arnon, Raynaud, Sophie D., Müller-Tidow, Carsten, Mesa, Ruben, Haferlach, Torsten, Gilliland, D. Gary, Tefferi, Ayalew, Ogawa, Seishi, Koeffler, H. Phillip

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Genome-wide analysis of histone H3 acetylation patterns in AML identifies PRDX2 as an epigenetically silenced tumor suppressor gene von Agrawal-Singh, Shuchi, Isken, Fabienne, Agelopoulos, Konstantin, Klein, Hans-Ulrich, Thoennissen, Nils H., Koehler, Gabriele, Hascher, Antje, Bäumer, Nicole, Berdel, Wolfgang E., Thiede, Christian, Ehninger, Gerhard, Becker, Anke, Schlenke, Peter, Wang, Yipeng, McClelland, Michael, Krug, Utz, Koschmieder, Steffen, Büchner, Thomas, Yu, Dae-Yeul, Singh, Shailendra Vikram, Hansen, Klaus, Serve, Hubert, Dugas, Martin, Müller-Tidow, Carsten

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The NPM1 mutation type has no impact on survival in cytogenetically normal AML von Pastore, Friederike, Greif, Philipp A, Schneider, Stephanie, Ksienzyk, Bianka, Mellert, Gudrun, Zellmeier, Evelyn, Braess, Jan, Sauerland, Cristina M, Heinecke, Achim, Krug, Utz, Berdel, Wolfgang E, Buechner, Thomas, Woermann, Bernhard, Hiddemann, Wolfgang, Spiekermann, Karsten

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A Phase I Dose Escalation Study of the Triple Angiokinase Inhibitor Nintedanib Combined with Low-Dose Cytarabine in Elderly Patients with Acute Myeloid Leukemia von Schliemann, Christoph, Gerss, Joachim, Wiebe, Stefanie, Mikesch, Jan-Henrik, Knoblauch, Nicola, Sauer, Tim, Angenendt, Linus, Kewitz, Tobias, Urban, Marc, Butterfass-Bahloul, Trude, Edemir, Sabine, Vehring, Kerstin, Müller-Tidow, Carsten, Berdel, Wolfgang E, Krug, Utz

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UBTF tandem duplications are rare but recurrent alterations in adult AML and associated with younger age, myelodysplasia, and inferior outcome von Georgi, Julia-Annabell, Stasik, Sebastian, Eckardt, Jan-Niklas, Zukunft, Sven, Hartwig, Marita, Röllig, Christoph, Middeke, Jan Moritz, Oelschlägel, Uta, Krug, Utz, Sauer, Tim, Scholl, Sebastian, Hochhaus, Andreas, Brümmendorf, Tim H., Naumann, Ralph, Steffen, Björn, Einsele, Hermann, Schaich, Markus, Burchert, Andreas, Neubauer, Andreas, Schäfer-Eckart, Kerstin, Schliemann, Christoph, Krause, Stefan W., Hänel, Mathias, Noppeney, Richard, Kaiser, Ulrich, Baldus, Claudia D., Kaufmann, Martin, Müller-Tidow, Carsten, Platzbecker, Uwe, Berdel, Wolfgang E., Serve, Hubert, Ehninger, Gerhard, Bornhäuser, Martin, Schetelig, Johannes, Kroschinsky, Frank, Thiede, Christian

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