Inhibition of Amino Acid Metabolism Selectively Targets Human Leukemia Stem Cells von Jones, Courtney L., Stevens, Brett M., D'Alessandro, Angelo, Reisz, Julie A., Culp-Hill, Rachel, Nemkov, Travis, Pei, Shanshan, Khan, Nabilah, Adane, Biniam, Ye, Haobin, Krug, Anna, Reinhold, Dominik, Smith, Clayton, DeGregori, James, Pollyea, Daniel A., Jordan, Craig T.

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Antibody Opsonization of a TLR9 Agonist-Containing Virus-like Particle Enhances In Situ Immunization von Lemke-Miltner, Caitlin D, Blackwell, Sue E, Yin, Chaobo, Krug, Anna E, Morris, Aaron J, Krieg, Arthur M, Weiner, George J

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A Novel Type of Monocytic Leukemia Stem Cell Revealed by the Clinical Use of Venetoclax-Based Therapy von Pei, Shanshan, Shelton, Ian T, Gillen, Austin E, Stevens, Brett M, Gasparetto, Maura, Wang, Yanan, Liu, Lina, Liu, Jun, Brunetti, Tonya M, Engel, Krysta, Staggs, Sarah, Showers, William, Sheth, Anagha Inguva, Amaya, Maria L, Minhajuddin, Mohammad, Winters, Amanda, Patel, Sweta B, Tolison, Hunter, Krug, Anna E, Young, Tracy N, Schowinsky, Jeffrey, McMahon, Christine M, Smith, Clayton A, Pollyea, Daniel A, Jordan, Craig T

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Inhibition of Amino Acid Metabolism Selectively Targets Human Leukemia Stem Cells von Jones, Courtney L., Stevens, Brett M., D’Alessandro, Angelo, Reisz, Julie A., Culp-Hill, Rachel, Nemkov, Travis, Pei, Shanshan, Khan, Nabilah, Adane, Biniam, Ye, Haobin, Krug, Anna, Reinhold, Dominik, Smith, Clayton, DeGregori, James, Pollyea, Daniel A., Jordan, Craig T.

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Lysosomal acid lipase A modulates leukemia stem cell response to venetoclax/tyrosine kinase inhibitor combination therapy in blast phase chronic myeloid leukemia von Minhajuddin, Mohd, Winters, Amanda, Ye, Haobin, Pei, Shanshan, Stevens, Brett, Gillen, Austin, Engel, Krysta, Gipson, Stephanie, Ransom, Monica, Amaya, Maria, Inguva, Anagha, Gasparetto, Maura, Althoff, Mark J, Miller, Regan, Shelton, Ian, Tolison, Hunter, Krug, Anna, Culp-Hill, Rachel, D'Alessandro, Angelo, Sherbenou, Daniel W, Pollyea, Daniel A, Smith, Clayton, Jordan, Craig T

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The Hepatic Microenvironment Uniquely Protects Leukemia Cells through Induction of Growth and Survival Pathways Mediated by LIPG von Ye, Haobin, Minhajuddin, Mohammad, Krug, Anna, Pei, Shanshan, Chou, Chih-Hsing, Culp-Hill, Rachel, Ponder, Jessica, De Bloois, Erik, Schniedewind, Björn, Amaya, Maria L, Inguva, Anagha, Stevens, Brett M, Pollyea, Daniel A, Christians, Uwe, Grimes, H Leighton, D'Alessandro, Angelo, Jordan, Craig T

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PB1761: PRECLINICAL EVALUATION OF THE MENIN INHIBITOR ZIFTOMENIB IN PRIMARY AML SPECIMENS von Stevens, Brett, Engel, Krysta, Gillen, Austin, Pei, Shanshan, Krug, Anna, Ransom, Monica, Staggs, Sarah, Burrows, Francis, Tomkinson, Blake, Kessler, Linda, Jordan, Craig, Smith, Clayton

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Differential Impact of Interferon Regulatory Factor 7 in Initiation of the Type I Interferon Response in the Lymphocytic Choriomeningitis Virus-Infected Central Nervous System vers... von CHRISTENSEN, Jeanette Erbo, FENGER, Christina, ISSAZADEH-NAVIKAS, Shohreh, KRUG, Anna, LILJESTRØM, Peter, GORIELY, Stanislas, PALUDAN, Søren Riis, FINSEN, Bente, CHRISTENSEN, Jan Pravsgaard, THOMSEN, Allan Randrup

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Nicotinamide Metabolism Mediates Resistance to Venetoclax in Relapsed Acute Myeloid Leukemia Stem Cells von Jones, Courtney L., Stevens, Brett M., Pollyea, Daniel A., Culp-Hill, Rachel, Reisz, Julie A., Nemkov, Travis, Gehrke, Sarah, Gamboni, Fabia, Krug, Anna, Winters, Amanda, Pei, Shanshan, Gustafson, Annika, Ye, Haobin, Inguva, Anagha, Amaya, Maria, Minhajuddin, Mohammad, Abbott, Diana, Becker, Michael W., DeGregori, James, Smith, Clayton A., D’Alessandro, Angelo, Jordan, Craig T.

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The STAT3-MYC axis promotes survival of leukemia stem cells by regulating SLC1A5 and oxidative phosphorylation von Amaya, Maria L., Inguva, Anagha, Pei, Shanshan, Jones, Courtney, Krug, Anna, Ye, Haobin, Minhajuddin, Mohammad, Winters, Amanda, Furtek, Steffanie L., Gamboni, Fabia, Stevens, Brett, D'Alessandro, Angelo, Pollyea, Daniel A., Reigan, Philip, Jordan, Craig T.

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Monocytic Subclones Confer Resistance to Venetoclax-Based Therapy in Patients with Acute Myeloid Leukemia von Pei, Shanshan, Pollyea, Daniel A, Gustafson, Annika, Stevens, Brett M, Minhajuddin, Mohammad, Fu, Rui, Riemondy, Kent A, Gillen, Austin E, Sheridan, Ryan M, Kim, Jihye, Costello, James C, Amaya, Maria L, Inguva, Anagha, Winters, Amanda, Ye, Haobin, Krug, Anna, Jones, Courtney L, Adane, Biniam, Khan, Nabilah, Ponder, Jessica, Schowinsky, Jeffrey, Abbott, Diana, Hammes, Andrew, Myers, Jason R, Ashton, John M, Nemkov, Travis, D'Alessandro, Angelo, Gutman, Jonathan A, Ramsey, Haley E, Savona, Michael R, Smith, Clayton A, Jordan, Craig T

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Fatty acid metabolism underlies venetoclax resistance in acute myeloid leukemia stem cells von Stevens, Brett M, Jones, Courtney L, Pollyea, Daniel A, Culp-Hill, Rachel, D'Alessandro, Angelo, Winters, Amanda, Krug, Anna, Abbott, Diana, Goosman, Madeline, Pei, Shanshan, Ye, Haobin, Gillen, Austin E, Becker, Michael W, Savona, Michael R, Smith, Clayton, Jordan, Craig T

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Impact of soy isoflavones on the epigenome von Gerhauser, Clarissa, Pudenz, Maria, Krug, Anna Lena

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Intracellular Calcium Localization Mediates the Activity of Venetoclax in Targeting Acute Myeloid Leukemia Stem Cells von Inguva, Anagha, Engel, Krysta L., Tolison, Hunter, Althoff, Mark J, Pei, Shanshan, Amaya, Maria L., Krug, Anna, Minhajuddin, Mohammad, Jones, Courtney L, Gillen, Austin E., Ransom, Monica, Staggs, Sarah, Pollyea, Daniel A., Smith, Clayton, Stevens, Brett M., Jordan, Craig T.

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STAT3 Plays a Critical Role in Mitochondrial Function and Survival of Primary AML Cells von Amaya, Maria L, Inguva, Anagha, Jones, Courtney L, Krug, Anna, Pei, Shanshan, Reigan, Phillip, Jordan, Craig T

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Targeting Mitochondrial Calcium Uptake to Eradicate Venetoclax-Resistant Acute Myeloid Leukemia Stem Cells von Sheth, Anagha Inguva, Engel, Krysta, Tolison, Hunter, Althoff, Mark Jordan, Krug, Anna, Amaya, Maria L, Pei, Shanshan, Young, Tracy, Patel, Sweta B, Minhajuddin, Mohd, Miller, Regan, Shelton, Ian, Vujovic, Ana, Jones, Courtney L, Gillen, Austin E, Ransom, Monica, Staggs, Sarah, Smith, Clayton, Pollyea, Daniel A., Stevens, Brett M, Jordan, Craig T.

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Lysosomal Acid Lipase a (LIPA) Modulates Leukemia Stem Cell (LSC) Response to Venetoclax/TKI Combination Therapy in Blast Phase Chronic Myeloid Leukemia von Minhajuddin, Mohd, Ye, Haobin, Winters, Amanda C., Pei, Shanshan, Khan, Nabilah, Stevens, Brett M., Adane, Biniam, Amaya, Maria L., Inguva, Anagha, Krug, Anna, Gasparetto, Maura, Sherbenou, Daniel W., Pollyea, Daniel A., Smith, Clayton, Jordan, Craig T.

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Inhibition of Fatty Acid Metabolism Re-Sensitizes Resistant Leukemia Stem Cells to Venetoclax with Azacitidine von Jones, Courtney L, Stevens, Brett M., Culp-Hill, Rachel, Dalessandro, Angelo, Krug, Anna, Goosman, Madeline, Pei, Shanshan, Pollyea, Daniel A, Jordan, Craig T

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Developmental Plasticity of Acute Myeloid Leukemia Mediates Resistance to Venetoclax-Based Therapy von Pei, Shanshan, Pollyea, Daniel A, Gustafson, Annika, Minhajuddin, Mohammad, Stevens, Brett M., Ye, Haobin, Inguva, Anagha, Amaya, Maria L, Krug, Anna, Jones, Courtney L, Adane, Biniam, Winters, Amanda, Khan, Nabilah, Ponder, Jessica, Schowinsky, Jeffrey, Hammes, Andrew, Abbott, Diana, Myers, Jason R, Ashton, John M, Gutman, Jonathan A, Purev, Enkhtsetseg, Ramsey, Haley E., Savona, Michael R., Fesik, Stephen W., Smith, Clayton, Jordan, Craig T

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Monocytic Subclones Confer Resistance to Venetoclax-Based Therapy in Acute Myeloid Leukemia Patients von Pei, Shanshan, Pollyea, Daniel A., Gustafson, Annika, Stevens, Brett M., Minhajuddin, Mohammad, Fu, Rui, Riemondy, Kent A., Gillen, Austin E., Sheridan, Ryan M., Kim, Jihye, Costello, James C., Amaya, Maria L., Inguva, Anagha, Winters, Amanda, Ye, Haobin, Krug, Anna, Jones, Courtney L., Adane, Biniam, Khan, Nabilah, Ponder, Jessica, Schowinsky, Jeffrey, Abbott, Diana, Hammes, Andrew, Myers, Jason R., Ashton, John M., Nemkov, Travis, D’Alessandro, Angelo, Gutman, Jonathan A., Ramsey, Haley E., Savona, Michael R., Smith, Clayton A., Jordan, Craig T.

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