Human Circulating PD-1+CXCR3−CXCR5+ Memory Tfh Cells Are Highly Functional and Correlate with Broadly Neutralizing HIV Antibody Responses von Locci, Michela, Havenar-Daughton, Colin, Landais, Elise, Wu, Jennifer, Kroenke, Mark A., Arlehamn, Cecilia L., Su, Laura F., Cubas, Rafael, Davis, Mark M., Sette, Alessandro, Haddad, Elias K., Poignard, Pascal, Crotty, Shane

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BCL6 orchestrates Tfh cell differentiation via multiple distinct mechanisms von Hatzi, Katerina, Nance, J Philip, Kroenke, Mark A, Bothwell, Marcella, Haddad, Elias K, Melnick, Ari, Crotty, Shane

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Bcl6 and Maf cooperate to instruct human follicular helper CD4 T cell differentiation von Kroenke, Mark A, Eto, Danelle, Locci, Michela, Cho, Michael, Davidson, Terence, Haddad, Elias K, Crotty, Shane

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GM-CSF-dependent, CD103+ dermal dendritic cells play a critical role in Th effector cell differentiation after subcutaneous immunization von King, Irah L, Kroenke, Mark A, Segal, Benjamin M

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IL-12- and IL-23-modulated T cells induce distinct types of EAE based on histology, CNS chemokine profile, and response to cytokine inhibition von Kroenke, Mark A, Carlson, Thaddeus J, Andjelkovic, Anuska V, Segal, Benjamin M

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Assay format diversity in pre-clinical immunogenicity risk assessment: Toward a possible harmonization of antigenicity assays von Ducret, Axel, Ackaert, Chloé, Bessa, Juliana, Bunce, Campbell, Hickling, Timothy, Jawa, Vibha, Kroenke, Mark A., Lamberth, Kasper, Manin, Anaïs, Penny, Hweixian L., Smith, Noel, Terszowski, Grzegorz, Tourdot, Sophie, Spindeldreher, Sebastian

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Immunogenicity Risk Assessment for Multi-specific Therapeutics von Kroenke, Mark A., Milton, Mark N., Kumar, Seema, Bame, Eris, White, Joleen T.

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Survey Outcome on Immunogenicity Risk Assessment Tools for Biotherapeutics: an Insight into Consensus on Methods, Application, and Utility in Drug Development von Gokemeijer, Jochem, Wen, Yi, Jawa, Vibha, Mitra-Kaushik, Shibani, Chung, Shan, Goggins, Alan, Kumar, Seema, Lamberth, Kasper, Liao, Karen, Lill, Jennie, Phung, Qui, Walsh, Robin, Roberts, Brian J., Swanson, Michael, Singh, Inderpal, Tourdot, Sophie, Kroenke, Mark A., Rup, Bonita, Goletz, Theresa J., Gupta, Swati, Malherbe, Laurent, Pattijn, Sofie

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The Th17-ELR+ CXC chemokine pathway is essential for the development of central nervous system autoimmune disease von Carlson, Thaddeus, Kroenke, Mark, Rao, Praveen, Lane, Thomas E, Segal, Benjamin

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EAE mediated by a non-IFN-γ/non-IL-17 pathway von Kroenke, Mark A, Chensue, Stephen W, Segal, Benjamin M

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Corrigendum: Translatability of findings from cynomolgus monkey to human suggests a mechanistic role for IL-21 in promoting immunogenicity to an anti-PD-1/IL-21 mutein fusion prote... von Kroenke, Mark A, Manning, Marta Starcevic, Zuch de Zafra, Christina L, Zhang, Xinwen, Cook, Kevin D, Archer, Michael, Lolkema, Martijn P, Wang, Jin, Hoofring, Sarah, Saini, Gurleen, Aeffner, Famke, Ahern, Elizabeth, Cabanas, Elena Garralda, Govindan, Ramaswamy, Hui, Mun, Gupta, Shalini, Mytych, Daniel T

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Translatability of findings from cynomolgus monkey to human suggests a mechanistic role for IL-21 in promoting immunogenicity to an anti-PD-1/IL-21 mutein fusion protein von Kroenke, Mark A, Starcevic Manning, Marta, Zuch de Zafra, Christina L, Zhang, Xinwen, Cook, Kevin D, Archer, Michael, Lolkema, Martijn P, Wang, Jin, Hoofring, Sarah, Saini, Gurleen, Aeffner, Famke, Ahern, Elizabeth, Cabanas, Elena Garralda, Govindan, Ramaswamy, Hui, Mun, Gupta, Shalini, Mytych, Daniel T

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Immune Complex Formation Is Associated With Loss of Tolerance and an Antibody Response to Both Drug and Target von Kroenke, Mark A., Barger, Troy E., Hu, Jenny, Miller, Mieke Jill, Kalenian, Kevin, He, Lidong, Hsu, Hailing, Bartley, Yessenia, Chow, Vincent Fung-Sing, Teixeira dos Santos, Marcia Cristina, Sullivan, Barbara A., Cheng, Laurence E., Parnes, Jane R., Padaki, Rupa, Kuhns, Scott, Mytych, Daniel T.

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Clinical immunogenicity of the d-amino acid peptide therapeutic etelcalcetide: Method development challenges and anti-drug antibody clinical impact assessments von Kroenke, Mark A., Weeraratne, Dohan K., Deng, Hongjie, Sloey, Bethlyn, Subramanian, Raju, Wu, Benjamin, Serenko, Michael, Hock, M. Benjamin

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IL-23 modulated myelin-specific T cells induce EAE via an IFNγ driven, IL-17 independent pathway von Kroenke, Mark A, Segal, Benjamin M

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Assay signal as an alternative to titer for assessment of magnitude of an antidrug antibody response von Starcevic Manning, Marta, Kroenke, Mark A, Lee, Stephanie A, Harrison, Simon E, Hoofring, Sarah A, Mytych, Daniel T, Jawa, Vibha

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Th17 and Th1 responses directed against the immunizing epitope, as opposed to secondary epitopes, dominate the autoimmune repertoire during relapses of experimental autoimmune ence... von Kroenke, Mark A., Segal, Benjamin M.

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Immunogenicity assessment of bispecific antibody-based immunotherapy in oncology von Zhou, Yanchen, Penny, Hweixian L, Kroenke, Mark A, Bautista, Bianca, Hainline, Kelly, Chea, Lynette S, Parnes, Jane, Mytych, Daniel T

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The function of IL-12 and IL-23 in central nervous system autoimmune disease von Kroenke, Mark A

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A Proposal to Redefine Clinical Immunogenicity Assessment von Mytych, Daniel T., Hock, M. Benjamin, Kroenke, Mark, Jawa, Vibha, Kaliyaperumal, Arunan, Zhou, Yanchen

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