A Menin-MLL Inhibitor Induces Specific Chromatin Changes and Eradicates Disease in Models of MLL-Rearranged Leukemia von Krivtsov, Andrei V., Evans, Kathryn, Gadrey, Jayant Y., Eschle, Benjamin K., Hatton, Charlie, Uckelmann, Hannah J., Ross, Kenneth N., Perner, Florian, Olsen, Sarah N., Pritchard, Tara, McDermott, Lisa, Jones, Connor D., Jing, Duohui, Braytee, Ali, Chacon, Diego, Earley, Eric, McKeever, Brian M., Claremon, David, Gifford, Andrew J., Lee, Heather J., Teicher, Beverly A., Pimanda, John E., Beck, Dominik, Perry, Jennifer A., Smith, Malcolm A., McGeehan, Gerard M., Lock, Richard B., Armstrong, Scott A.

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A UTX-MLL4-p300 Transcriptional Regulatory Network Coordinately Shapes Active Enhancer Landscapes for Eliciting Transcription von Wang, Shu-Ping, Tang, Zhanyun, Chen, Chun-Wei, Shimada, Miho, Koche, Richard P., Wang, Lan-Hsin, Nakadai, Tomoyoshi, Chramiec, Alan, Krivtsov, Andrei V., Armstrong, Scott A., Roeder, Robert G.

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DNMT3A mutations promote anthracycline resistance in acute myeloid leukemia via impaired nucleosome remodeling von Guryanova, Olga A, Shank, Kaitlyn, Spitzer, Barbara, Luciani, Luisa, Koche, Richard P, Garrett-Bakelman, Francine E, Ganzel, Chezi, Durham, Benjamin H, Mohanty, Abhinita, Hoermann, Gregor, Rivera, Sharon A, Chramiec, Alan G, Pronier, Elodie, Bastian, Lennart, Keller, Matthew D, Tovbin, Daniel, Loizou, Evangelia, Weinstein, Abby R, Gonzalez, Adriana Rodriguez, Lieu, Yen K, Rowe, Jacob M, Pastore, Friederike, McKenney, Anna Sophia, Krivtsov, Andrei V, Sperr, Wolfgang R, Cross, Justin R, Mason, Christopher E, Tallman, Martin S, Arcila, Maria E, Abdel-Wahab, Omar, Armstrong, Scott A, Kubicek, Stefan, Staber, Philipp B, Gönen, Mithat, Paietta, Elisabeth M, Melnick, Ari M, Nimer, Stephen D, Mukherjee, Siddhartha, Levine, Ross L

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Mediator kinase inhibition further activates super-enhancer-associated genes in AML von Pelish, Henry E., Liau, Brian B., Nitulescu, Ioana I., Tangpeerachaikul, Anupong, Poss, Zachary C., Da Silva, Diogo H., Caruso, Brittany T., Arefolov, Alexander, Fadeyi, Olugbeminiyi, Christie, Amanda L., Du, Karrie, Banka, Deepti, Schneider, Elisabeth V., Jestel, Anja, Zou, Ge, Si, Chong, Ebmeier, Christopher C., Bronson, Roderick T., Krivtsov, Andrei V., Myers, Andrew G., Kohl, Nancy E., Kung, Andrew L., Armstrong, Scott A., Lemieux, Madeleine E., Taatjes, Dylan J., Shair, Matthew D.

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Loss of BAP1 function leads to EZH2-dependent transformation von LaFave, Lindsay M, Béguelin, Wendy, Koche, Richard, Teater, Matt, Spitzer, Barbara, Chramiec, Alan, Papalexi, Efthymia, Keller, Matthew D, Hricik, Todd, Konstantinoff, Katerina, Micol, Jean-Baptiste, Durham, Benjamin, Knutson, Sarah K, Campbell, John E, Blum, Gil, Shi, Xinxu, Doud, Emma H, Krivtsov, Andrei V, Chung, Young Rock, Khodos, Inna, de Stanchina, Elisa, Ouerfelli, Ouathek, Adusumilli, Prasad S, Thomas, Paul M, Kelleher, Neil L, Luo, Minkui, Keilhack, Heike, Abdel-Wahab, Omar, Melnick, Ari, Armstrong, Scott A, Levine, Ross L

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SETD2 alterations impair DNA damage recognition and lead to resistance to chemotherapy in leukemia von Mar, Brenton G., Chu, S. Haihua, Kahn, Josephine D., Krivtsov, Andrei V., Koche, Richard, Castellano, Cecilia A., Kotlier, Jacob L., Zon, Rebecca L., McConkey, Marie E., Chabon, Jonathan, Chappell, Ryan, Grauman, Peter V., Hsieh, James J., Armstrong, Scott A., Ebert, Benjamin L.

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Hematopoietic Differentiation Is Required for Initiation of Acute Myeloid Leukemia von Ye, Min, Zhang, Hong, Yang, Henry, Koche, Richard, Staber, Philipp B., Cusan, Monica, Levantini, Elena, Welner, Robert S., Bach, Christian S., Zhang, Junyan, Krivtsov, Andrei V., Armstrong, Scott A., Tenen, Daniel G.

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Positive Streamer in the Surface Dielectric Barrier Discharge in Air: Numerical Modelling and Analytical Estimations von Soloviev, V, Krivtsov, V

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Peptidomimetic blockade of MYB in acute myeloid leukemia von Ramaswamy, Kavitha, Forbes, Lauren, Minuesa, Gerard, Gindin, Tatyana, Brown, Fiona, Kharas, Michael G., Krivtsov, Andrei V., Armstrong, Scott A., Still, Eric, de Stanchina, Elisa, Knoechel, Birgit, Koche, Richard, Kentsis, Alex

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Surface barrier discharge modelling for aerodynamic applications von Soloviev, V R, Krivtsov, V M

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Requirement for CDK6 in MLL-rearranged acute myeloid leukemia von Placke, Theresa, Faber, Katrin, Nonami, Atsushi, Putwain, Sarah L., Salih, Helmut R., Heidel, Florian H., Krämer, Alwin, Root, David E., Barbie, David A., Krivtsov, Andrei V., Armstrong, Scott A., Hahn, William C., Huntly, Brian J., Sykes, Stephen M., Milsom, Michael D., Scholl, Claudia, Fröhling, Stefan

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HOXA9 is required for survival in human MLL-rearranged acute leukemias von Faber, Joerg, Krivtsov, Andrei V., Stubbs, Matthew C., Wright, Renee, Davis, Tina N., van den Heuvel-Eibrink, Marry, Zwaan, Christian M., Kung, Andrew L., Armstrong, Scott A.

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Cell of origin determines clinically relevant subtypes of MLL-rearranged AML von Krivtsov, A V, Figueroa, M E, Sinha, A U, Stubbs, M C, Feng, Z, Valk, P J M, Delwel, R, Döhner, K, Bullinger, L, Kung, A L, Melnick, A M, Armstrong, S A

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Evolution of nanosecond surface dielectric barrier discharge for negative polarity of a voltage pulse von Soloviev, V R, Krivtsov, V M, Shcherbanev, S A, Starikovskaia, S M

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H3K79 Methylation Profiles Define Murine and Human MLL-AF4 Leukemias von Krivtsov, Andrei V., Feng, Zhaohui, Lemieux, Madeleine E., Faber, Joerg, Vempati, Sridhar, Sinha, Amit U., Xia, Xiaobo, Jesneck, Jonathan, Bracken, Adrian P., Silverman, Lewis B., Kutok, Jeffery L., Kung, Andrew L., Armstrong, Scott A.

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Transition Radiation on a Conducting Target Shaped as a Right Dihedral Angle von Syshchenko, V. V., Tarnovsky, A. I., Krivtsov, V. A.

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Investigations of indirect relationships in ecology and environmental sciences: a review and the implications for comparative theoretical ecosystem analysis von Krivtsov, V

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MLL-AF9 and FLT3 cooperation in acute myelogenous leukemia: development of a model for rapid therapeutic assessment von Stubbs, M C, Kim, Y M, Krivtsov, A V, Wright, R D, Feng, Z, Agarwal, J, Kung, A L, Armstrong, S A

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Patient-derived xenotransplants can recapitulate the genetic driver landscape of acute leukemias von Wang, K, Sanchez-Martin, M, Wang, X, Knapp, K M, Koche, R, Vu, L, Nahas, M K, He, J, Hadler, M, Stein, E M, Tallman, M S, Donahue, A L, Frampton, G M, Lipson, D, Roels, S, Stephens, P J, Sanford, E M, Brennan, T, Otto, G A, Yelensky, R, Miller, V A, Kharas, M G, Levine, R L, Ferrando, A, Armstrong, S A, Krivtsov, A V

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MLL translocations, histone modifications and leukaemia stem-cell development von Armstrong, Scott A, Krivtsov, Andrei V

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