Molecular implications of MUC5AC-CD44 axis in colorectal cancer progression and chemoresistance von Pothuraju, Ramesh, Rachagani, Satyanarayana, Krishn, Shiv Ram, Chaudhary, Sanjib, Nimmakayala, Rama Krishna, Siddiqui, Jawed A., Ganguly, Koelina, Lakshmanan, Imayavaramban, Cox, Jesse L., Mallya, Kavita, Kaur, Sukhwinder, Batra, Surinder K.

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Mucin 5AC Serves as the Nexus for β-Catenin/c-Myc Interplay to Promote Glutamine Dependency During Pancreatic Cancer Chemoresistance von Ganguly, Koelina, Bhatia, Rakesh, Rauth, Sanchita, Kisling, Andrew, Atri, Pranita, Thompson, Christopher, Vengoji, Raghupathy, Ram Krishn, Shiv, Shinde, Dhananjay, Thomas, Vinai, Kaur, Sukhwinder, Mallya, Kavita, Cox, Jesse L., Kumar, Sushil, Batra, Surinder K.

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Small Extracellular Vesicle Regulation of Mitochondrial Dynamics Reprograms a Hypoxic Tumor Microenvironment von Bertolini, Irene, Ghosh, Jagadish C., Kossenkov, Andrew V., Mulugu, Sudheer, Krishn, Shiv Ram, Vaira, Valentina, Qin, Jun, Plow, Edward F., Languino, Lucia R., Altieri, Dario C.

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Secretory Mucin 5AC Promotes Neoplastic Progression by Augmenting KLF4-Mediated Pancreatic Cancer Cell Stemness von Ganguly, Koelina, Krishn, Shiv Ram, Rachagani, Satyanarayana, Jahan, Rahat, Shah, Ashu, Nallasamy, Palanisamy, Rauth, Sanchita, Atri, Pranita, Cox, Jesse L, Pothuraju, Ramesh, Smith, Lynette M, Ayala, Sudhua, Evans, Christopher, Ponnusamy, Moorthy P, Kumar, Sushil, Kaur, Sukhwinder, Batra, Surinder K

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Small extracellular vesicle-mediated ITGB6 siRNA delivery downregulates the αVβ6 integrin and inhibits adhesion and migration of recipient prostate cancer cells von Krishn, Shiv Ram, Garcia, Vaughn, Naranjo, Nicole M., Quaglia, Fabio, Shields, Christopher D., Harris, Maisha A., Kossenkov, Andrew V., Liu, Qin, Corey, Eva, Altieri, Dario C., Languino, Lucia R.

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Myc-mediated transcriptional regulation of the mitochondrial chaperone TRAP1 controls primary and metastatic tumor growth von Agarwal, Ekta, Altman, Brian J., Seo, Jae Ho, Ghosh, Jagadish C., Kossenkov, Andrew V., Tang, Hsin-Yao, Krishn, Shiv Ram, Languino, Lucia R., Gabrilovich, Dmitry I., Speicher, David W., Dang, Chi V., Altieri, Dario C.

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1426 Combination with BCA101 improves the efficacy of KRAS-G12C inhibitor and overcomes G12C inhibitor-induced resistance in lung and colon cancer cell lines von Nair, Reshmi, Somasundaram, Veena, Krishn, Shiv Ram, Salazar, Rachel, Nair, Pradip

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The NOGO receptor NgR2, a novel αVβ3 integrin effector, induces neuroendocrine differentiation in prostate cancer von Quaglia, Fabio, Krishn, Shiv Ram, Sossey-Alaoui, Khalid, Rana, Priyanka Shailendra, Pluskota, Elzbieta, Park, Pyung Hun, Shields, Christopher D., Lin, Stephen, McCue, Peter, Kossenkov, Andrew V., Wang, Yanqing, Goodrich, David W., Ku, Sheng-Yu, Beltran, Himisha, Kelly, William K., Corey, Eva, Klose, Maja, Bandtlow, Christine, Liu, Qin, Altieri, Dario C., Plow, Edward F., Languino, Lucia R.

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Differential expression of αVβ3 and αVβ6 integrins in prostate cancer progression von Quaglia, Fabio, Krishn, Shiv Ram, Wang, Yanqing, Goodrich, David W, McCue, Peter, Kossenkov, Andrew V, Mandigo, Amy C, Knudsen, Karen E, Weinreb, Paul H, Corey, Eva, Kelly, William K, Languino, Lucia R

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Small extracellular vesicles modulated by αVβ3 integrin induce neuroendocrine differentiation in recipient cancer cells von Quaglia, Fabio, Krishn, Shiv Ram, Daaboul, George G., Sarker, Srawasti, Pippa, Raffaella, Domingo-Domenech, Josep, Kumar, Gaurav, Fortina, Paolo, McCue, Peter, Kelly, William K., Beltran, Himisha, Liu, Qin, Languino, Lucia R.

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The αvβ6 integrin in cancer cell-derived small extracellular vesicles enhances angiogenesis von Krishn, Shiv Ram, Salem, Israa, Quaglia, Fabio, Naranjo, Nicole M., Agarwal, Ekta, Liu, Qin, Sarker, Srawasti, Kopenhaver, Jessica, McCue, Peter A., Weinreb, Paul H., Violette, Shelia M., Altieri, Dario C., Languino, Lucia R.

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Tumor-Derived Extracellular Vesicles Require β1 Integrins to Promote Anchorage-Independent Growth von DeRita, Rachel M, Sayeed, Aejaz, Garcia, Vaughn, Krishn, Shiv Ram, Shields, Christopher D, Sarker, Srawasti, Friedman, Andrea, McCue, Peter, Molugu, Sudheer Kumar, Rodeck, Ulrich, Dicker, Adam P, Languino, Lucia R

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Acinar transformed ductal cells exhibit differential mucin expression in a tamoxifen-induced pancreatic ductal adenocarcinoma mouse model von Mallya, Kavita, Haridas, Dhanya, Seshacharyulu, Parthasarathy, Pothuraju, Ramesh, Junker, Wade M., Krishn, Shiv Ram, Muniyan, Sakthivel, Vengoji, Raghupathy, Batra, Surinder K., Rachagani, Satyanarayana

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Mucins and associated O-glycans based immunoprofile for stratification of colorectal polyps: clinical implication for improved colon surveillance von Krishn, Shiv Ram, Kaur, Sukhwinder, Sheinin, Yuri M, Smith, Lynette M, Gautam, Shailendra K, Patel, Asish, Jain, Maneesh, Juvvigunta, Vasthala, Pai, Priya, Lazenby, Audrey J, Roy, Hemant K, Batra, Surinder K

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Ramifications of secreted mucin MUC5AC in malignant journey: a holistic view von Krishn, Shiv Ram, Ganguly, Koelina, Kaur, Sukhwinder, Batra, Surinder K

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Secretory Mucin SAC Promotes Neoplastic Progression by Augmenting KLF4-Mediated Pancreatic Cancer Cell Sternness von Ganguly, Koelina, Krishn, Shiv Ram, Rachagani, Satyanarayana, Jahan, Rahat, Shah, Ashu, Nallasamy, Palanisamy, Rauth, Sanchita, Atri, Pranita, Cox, Jesse L., Pothuraju, Ramesh, Smith, Lynette M., Ayala, Sudha, Evans, Christopher, Ponusamy, Moorthy P., Kumar, Sushil, Kaur, Sukhwinder, Batra, Surinder K.

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Prostate cancer sheds the αvβ3 integrin in vivo through exosomes von Krishn, Shiv Ram, Singh, Amrita, Bowler, Nicholas, Duffy, Alexander N., Friedman, Andrea, Fedele, Carmine, Kurtoglu, Senem, Tripathi, Sushil K., Wang, Kerith, Hawkins, Adam, Sayeed, Aejaz, Goswami, Chirayu P., Thakur, Madhukar L., Iozzo, Renato V., Peiper, Stephen C., Kelly, William K., Languino, Lucia R.

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Mechanistic and Functional Shades of Mucins and Associated Glycans in Colon Cancer von Pothuraju, Ramesh, Krishn, Shiv Ram, Gautam, Shailendra K., Pai, Priya, Ganguly, Koelina, Chaudhary, Sanjib, Rachagani, Satyanarayana, Kaur, Sukhwinder, Batra, Surinder K.

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Differential expression of alpha V beta 3 and alpha V beta 6 integrins in prostate cancer progression von Quaglia, Fabio, Krishn, Shiv Ram, Wang, Yanqing, Goodrich, David W., McCue, Peter, Kossenkov, Andrew, Mandigo, Amy C., Knudsen, Karen E., Weinreb, Paul H., Corey, Eva, Kelly, William K., Languino, Lucia R.

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BCA101 Is a Tumor-Targeted Bifunctional Fusion Antibody That Simultaneously Inhibits EGFR and TGFβ Signaling to Durably Suppress Tumor Growth von Boreddy, Srinivas Reddy, Nair, Reshmi, Pandey, Prashant Kumar, Kuriakose, Anshu, Marigowda, Shivakumar Bhadravathi, Dey, Chaitali, Banerjee, Arindam, Kulkarni, Hanumant, Sagar, Milind, Krishn, Shiv Ram, Rao, Shruthi, Ar, Madhukara, Tiwari, Vinita, Alke, Bhavna, Mv, Prashantha Kumar, Shri, Meena, Dhamne, Chaitrali, Patel, Sonal, Sharma, Pinky, Periyasamy, Sankar, Bhatnagar, Jaya, Kuriakose, Moni Abraham, Reddy, Ram Bhupal, Suresh, Amritha, Sreenivas, Suma, Govindappa, Nagaraja, Moole, Praveen Reddy, Bughani, Usha, Tan, Seng-Lai, Nair, Pradip

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