Preclinical Efficacy and Safety of a Human Embryonic Stem Cell-Derived Midbrain Dopamine Progenitor Product, MSK-DA01 von Piao, Jinghua, Zabierowski, Susan, Dubose, Brittany N., Hill, Ellen J., Navare, Monalisa, Claros, Nidia, Rosen, Siera, Ramnarine, Kiran, Horn, Callie, Fredrickson, Craig, Wong, Karen, Safford, Brent, Kriks, Sonja, El Maarouf, Abderrahman, Rutishauser, Urs, Henchcliffe, Claire, Wang, Yongzeng, Riviere, Isabelle, Mann, Shannon, Bermudez, Vladimir, Irion, Stefan, Studer, Lorenz, Tomishima, Mark, Tabar, Viviane

Volltext

Biphasic Activation of WNT Signaling Facilitates the Derivation of Midbrain Dopamine Neurons from hESCs for Translational Use von Kim, Tae Wan, Piao, Jinghua, Koo, So Yeon, Kriks, Sonja, Chung, Sun Young, Betel, Doron, Socci, Nicholas D., Choi, Se Joon, Zabierowski, Susan, Dubose, Brittany N., Hill, Ellen J., Mosharov, Eugene V., Irion, Stefan, Tomishima, Mark J., Tabar, Viviane, Studer, Lorenz

Volltext

Human iPSC-Based Modeling of Late-Onset Disease via Progerin-Induced Aging von Miller, Justine D., Ganat, Yosif M., Kishinevsky, Sarah, Bowman, Robert L., Liu, Becky, Tu, Edmund Y., Mandal, Pankaj K., Vera, Elsa, Shim, Jae-won, Kriks, Sonja, Taldone, Tony, Fusaki, Noemi, Tomishima, Mark J., Krainc, Dimitri, Milner, Teresa A., Rossi, Derrick J., Studer, Lorenz

Volltext

Specification of Functional Cranial Placode Derivatives from Human Pluripotent Stem Cells von Dincer, Zehra, Piao, Jinghua, Niu, Lei, Ganat, Yosif, Kriks, Sonja, Zimmer, Bastian, Shi, Song-Hai, Tabar, Viviane, Studer, Lorenz

Volltext

Identification of embryonic stem cell-derived midbrain dopaminergic neurons for engraftment von Ganat, Yosif M, Calder, Elizabeth L, Kriks, Sonja, Nelander, Jenny, Tu, Edmund Y, Jia, Fan, Battista, Daniela, Harrison, Neil, Parmar, Malin, Tomishima, Mark J, Rutishauser, Urs, Studer, Lorenz

Volltext

Ascl1 and Gsh1/2 control inhibitory and excitatory cell fate in spinal sensory interneurons von Goulding, Martyn, Mizuguchi, Rumiko, Kriks, Sonja, Cordes, Ralf, Gossler, Achim, Ma, Qiufu

Volltext

Gbx1 and Gbx2 Are Essential for Normal Patterning and Development of Interneurons and Motor Neurons in the Embryonic Spinal Cord von Buckley, Desirè M, Burroughs-Garcia, Jessica, Kriks, Sonja, Lewandoski, Mark, Waters, Samuel T

Volltext

A Cell Engineering Strategy to Enhance the Safety of Stem Cell Therapies von Oricchio, Elisa, Papapetrou, Eirini P., Lafaille, Fabien, Ganat, Yosif M., Kriks, Sonja, Ortega-Molina, Ana, Mark, Willie H., Teruya-Feldstein, Julie, Huse, Jason T., Reuter, Victor, Sadelain, Michel, Studer, Lorenz, Wendel, Hans-Guido

Volltext

Gsh2 is required for the repression of Ngn1 and specification of dorsal interneuron fate in the spinal cord von Kriks, Sonja, Lanuza, Guillermo M, Mizuguchi, Rumiko, Nakafuku, Masato, Goulding, Martyn

Volltext

Dopamine neurons derived from human ES cells efficiently engraft in animal models of Parkinson’s disease von Kriks, Sonja, Shim, Jae-Won, Piao, Jinghua, Ganat, Yosif M., Wakeman, Dustin R., Xie, Zhong, Carrillo-Reid, Luis, Auyeung, Gordon, Antonacci, Chris, Buch, Amanda, Yang, Lichuan, Beal, M. Flint, Surmeier, D. James, Kordower, Jeffrey H., Tabar, Viviane, Studer, Lorenz

Volltext

Deriving human ENS lineages for cell therapy and drug discovery in Hirschsprung disease von Fattahi, Faranak, Steinbeck, Julius A, Kriks, Sonja, Tchieu, Jason, Zimmer, Bastian, Kishinevsky, Sarah, Zeltner, Nadja, Mica, Yvonne, El-Nachef, Wael, Zhao, Huiyong, de Stanchina, Elisa, Gershon, Michael D., Grikscheit, Tracy C., Chen, Shuibing, Studer, Lorenz

Volltext

The polycomb group protein L3MBTL1 represses a SMAD5-mediated hematopoietic transcriptional program in human pluripotent stem cells von Perna, Fabiana, Vu, Ly P, Themeli, Maria, Kriks, Sonja, Hoya-Arias, Ruben, Khanin, Raya, Hricik, Todd, Mansilla-Soto, Jorge, Papapetrou, Eirini P, Levine, Ross L, Studer, Lorenz, Sadelain, Michel, Nimer, Stephen D

Volltext

Human pallial MGE-type GABAergic interneuron cell therapy for chronic focal epilepsy von Bershteyn, Marina, Bröer, Sonja, Parekh, Mansi, Maury, Yves, Havlicek, Steven, Kriks, Sonja, Fuentealba, Luis, Lee, Seonok, Zhou, Robin, Subramanyam, Geetha, Sezan, Meliz, Sevilla, Eric Steven, Blankenberger, Whitney, Spatazza, Julien, Zhou, Li, Nethercott, Hubert, Traver, David, Hampel, Philip, Kim, Hannah, Watson, Michael, Salter, Naomi, Nesterova, Anastasia, Au, Wai, Kriegstein, Arnold, Alvarez-Buylla, Arturo, Rubenstein, John, Banik, Gautam, Bulfone, Alessandro, Priest, Catherine, Nicholas, Cory R.

Volltext

First-in-Human Trial of NRTX-1001 GABAergic Interneuron Cell Therapy for Treatment of Focal Epilepsy - Emerging Clinical Trial Results (S19.002) von Babu, Harish, Beach, Robert, Ben-Haim, Sharona, Burchiel, Kim, Luedke, Matthew, O’Dwyer, Rebecca, Sani, Sepher, Shih, Jerry, Southwell, Derek, Spencer, David, Banik, Gautam, Bershteyn, Marina, Blum, David, Bulfone, Alessandro, Feld, Brianna, Finefrock, Holly, Fuentealba, Luis, Hixson, John, Hosford, Victoria, Jung, Ji-Hye, Kowal, Tia, Kriks, Sonja, Larios, Rose, Lee, Seonok, Madrid, Sheri, Maury, Yves, Priest, Catherine, Shevchuk, Kiril, Shevchuk, Sergei, Nicholas, Cory

Volltext

DERIVING HUMAN ENS LINEAGES FOR CELL THERAPY AND DRUG DISCOVERY IN HIRSCHSPRUNG'S DISEASE von Fattahi, Faranak, Steinbeck, Julius A, Kriks, Sonja, Tchieu, Jason, Zimmer, Bastian, Kishinevsky, Sarah, Zeltner, Nadja, Mica, Yvonne, El-Nachef, Wael, Zhao, Huiyong, de Stanchina, Elisa, Gershon, Michael D., Grikscheit, Tracy C., Chen, Shuibing, Studer, Lorenz

Volltext

Floor plate-derived dopamine neurons from hESCs efficiently engraft in animal models of PD von Kriks, Sonja, Shim, Jae-Won, Piao, Jinghua, Ganat, Yosif M., Wakeman, Dustin R., Xie, Zhong, Carrillo-Reid, Luis, Auyeung, Gordon, Antonacci, Chris, Buch, Amanda, Yang, Lichuan, Beal, M. Flint, Surmeier, D. James, Kordower, Jeffrey H., Tabar, Viviane, Studer, Lorenz

Volltext

Midbrain dopamine (DA) neurons for engraftment von STUDER, Lorenz, KRIKS, Sonja, SHIM, Jae-Won

Volltext bestellen

MIDBRAIN DOPAMINE (DA) NEURONS FOR ENGRAFTMENT von Shim, Jae-Won, Studer, Lorenz, Kriks, Sonja

Volltext bestellen

Midbrain dopamine (DA) neurons for engraftment von STUDER, Lorenz, KRIKS, Sonja, SHIM, Jae-Won

Volltext bestellen

Midbrain dopamine (DA) neurons for engraftment von Shim, Jae-Won, Studer, Lorenz, Kriks, Sonja

Volltext bestellen