Pharmacodynamic and pharmacogenomic study of the nanoparticle conjugate of camptothecin CRLX101 for the treatment of cancer von Gaur, Shikha, PhD, Wang, Yafan, MS, MPH, Kretzner, Leo, PhD, Chen, Linling, MS, Yen, Terence, Wu, Xiwei, PhD, Yuan, Yate-Ching, PhD, Davis, Mark, PhD, Yen, Yun, MD, PhD

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The novel histone deacetylase inhibitor, LBH589, induces expression of DNA damage response genes and apoptosis in Ph− acute lymphoblastic leukemia cells von Scuto, Anna, Kirschbaum, Mark, Kowolik, Claudia, Kretzner, Leo, Juhasz, Agnes, Atadja, Peter, Pullarkat, Vinod, Bhatia, Ravi, Forman, Stephen, Yen, Yun, Jove, Richard

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Preclinical Results of Camptothecin-Polymer Conjugate (IT-101) in Multiple Human Lymphoma Xenograft Models von Numbenjapon, Tontanai, Wang, Jianyi, Colcher, David, Schluep, Thomas, Davis, Mark E, Duringer, Julienne, Kretzner, Leo, Yen, Yun, Forman, Stephen J, Raubitschek, Andrew

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Human non-CG methylation: Are human stem cells plant-like? von Dyachenko, Olga V., Schevchuk, Tara V., Kretzner, Leo, Buryanov, Yaroslav I., Smith, Steven S.

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Myc and Max proteins possess distinct transcriptional activities von Kretzner, Leo, Blackwood, Elizabeth M, Eisenman, Robert N

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Sequence-Specific DNA Binding by the c-Myc Protein von Blackwell, T. Keith, Kretzner, Leo, Blackwood, Elizabeth M., Eisenman, Robert N., Weintraub, Harold

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The novel JAK inhibitor AZD1480 blocks STAT3 and FGFR3 signaling, resulting in suppression of human myeloma cell growth and survival von Scuto, A, Krejci, P, Popplewell, L, Wu, J, Wang, Y, Kujawski, M, Kowolik, C, Xin, H, Chen, L, Kretzner, L, Yu, H, Wilcox, W R, Yen, Y, Forman, S, Jove, R

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Combining Histone Deacetylase Inhibitor Vorinostat with Aurora Kinase Inhibitors Enhances Lymphoma Cell Killing with Repression of c-Myc, hTERT, and microRNA Levels von KRETZNER, Leo, SCUTO, Anna, DINO, Pamela M, KOWOLIK, Claudia M, JUN WU, VENTURA, Patrick, JOVE, Richard, FORMAN, Stephen J, YUN YEN, KIRSCHBAUM, Mark H

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Myc and Max function as a nucleoprotein complex von Blackwood, Elizabeth M., Kretzner, Leo, Eisenman, Robert N.

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The growth-inhibitory Ndrg1 gene is a Myc negative target in human neuroblastomas and other cell types with overexpressed N- or c-myc von Li, Jun, Kretzner, Leo

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Characterization of the Chicken CTCF Genomic Locus, and Initial Study of the Cell Cycle-regulated Promoter of the Gene von Klenova, Elena M., Fagerlie, Sara, Filippova, Galina N., Kretzner, Leo, Goodwin, Graham H., Loring, Gilbert, Neiman, Paul E., Lobanenkov, Victor V.

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Mad: A heterodimeric partner for Max that antagonizes Myc transcriptional activity von Ayer, Donald E., Kretzner, Leo, Eisenman, Robert N.

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Combination Therapy with the Histone Deacetylase Inhibitor Vorinostat Plus the Novel Aurora Kinase A Inhibitor MK-5108 Leads to Enhanced Lymphoma Cell Death Due to Acetylation of p... von Kretzner, Leo, Scuto, Anna, Claudia, Kowolik, Jove, Richard, Forman, Stephen J, Yen, Yun, Kirschbaum, Mark

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Combining histone deacetylase inhibitor vorinostat with aurora kinase inhibitors enhances lymphoma cell killing with repression of c-Myc, hTERT, and micro-RNA levels von Kretzner, Leo, Scuto, Anna, Dino, Pamela M., Kowolik, Claudia M., Wu, Jun, Ventura, Patrick, Jove, Richard, Forman, Stephen J., Yen, Yun, Kirschbaum, Mark H.

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Combination Therapy with Histone Deacetylase Inhibitor Vorinostat Plus Aurora Kinase Inhibitor MK-0457 Leads to Enhanced Lymphoma Cell Killing with Stabilization of p53 and Repress... von Kretzner, Leo, Scuto, Anna, Jove, Richard, Forman, Stephen J., Yen, Yun, Kirschbaum, Mark

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Prostate cancer molecular markers GSTP1 and hTERT in expressed prostatic secretions as predictors of biopsy results von Crocitto, Laura E., Korns, Darlynn, Kretzner, Leo, Shevchuk, Taras, Blair, Sarah L., Wilson, Timothy G., Ramin, Soroush A., Kawachi, Mark H., Smith, Steven S.

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Binding of myc proteins to canonical and noncanonical DNA sequences von BLACKWELL, T. K, JING HUANG, AVERIL MA, KRETZNER, L, ALT, F. W, EISENMAN, R. N, WEINTRAUB, H

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Combination of the Histone Deacetylase Inhibitor Vorinostat and Dasatinib Increases Apoptosis in Bcr-abl+ Cells and Reverses Changes Associated with CML Progression von Kretzner, Leo, Scuto, Anna, Juhasz, Agnes, Jove, Richard, Yen, Yun, Forman, Stephen J., Kirschbaum, Mark

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Autorepression of c-myc requires both initiator and E2F-binding site elements and cooperation with the p107 gene product von Luo, Qi, Li, Jun, Cenkci, Belgin, Kretzner, Leo

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Transgene-induced CCWGG methylation does not alter CG methylation patterning in human kidney cells von Shevchuk, Taras, Kretzner, Leo, Munson, Kristofer, Axume, John, Clark, Jarrod, Dyachenko, Olga V., Caudill, Marie, Buryanov, Yaroslav, Smith, Steven S.

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