RETaliation-Tackling Rare Resistance Alterations to Osimertinib von Krebs, Matthew G, Popat, Sanjay

Volltext

Amivantamab in EGFR Exon 20 Insertion-Mutated Non-Small-Cell Lung Cancer Progressing on Platinum Chemotherapy: Initial Results From the CHRYSALIS Phase I Study von Park, Keunchil, Haura, Eric B., Leighl, Natasha B., Mitchell, Paul, Shu, Catherine A., Girard, Nicolas, Viteri, Santiago, Han, Ji-Youn, Kim, Sang-We, Lee, Chee Khoon, Sabari, Joshua K., Spira, Alexander, Yang, Tsung-Ying, Kim, Dong-Wan, Lee, Ki Hyeong, Sanborn, Rachel E., Trigo, Jose, Goto, Koichi, Lee, Jong-Seok, Yang, James Chih-Hsin, Govindan, Ramaswamy, Bauml, Joshua M., Garrido, Pilar, Krebs, Matthew G., Reckamp, Karen L., Xie, John, Curtin, Joshua C., Haddish-Berhane, Nahor, Roshak, Amy, Millington, Dawn, Lorenzini, Patricia, Thayu, Meena, Knoblauch, Roland E., Cho, Byoung Chul

Volltext

Entrectinib in ROS1 fusion-positive non-small-cell lung cancer: integrated analysis of three phase 1–2 trials von Drilon, Alexander, Siena, Salvatore, Dziadziuszko, Rafal, Barlesi, Fabrice, Krebs, Matthew G, Shaw, Alice T, de Braud, Filippo, Rolfo, Christian, Ahn, Myung-Ju, Wolf, Jürgen, Seto, Takashi, Cho, Byoung Chul, Patel, Manish R, Chiu, Chao-Hua, John, Thomas, Goto, Koichi, Karapetis, Christos S, Arkenau, Hendrick-Tobias, Kim, Sang-We, Ohe, Yuichiro, Li, Yu-Chung, Chae, Young K, Chung, Christine H, Otterson, Gregory A, Murakami, Haruyasu, Lin, Chia-Chi, Tan, Daniel S W, Prenen, Hans, Riehl, Todd, Chow-Maneval, Edna, Simmons, Brian, Cui, Na, Johnson, Ann, Eng, Susan, Wilson, Timothy R, Doebele, Robert C

Volltext

Ramucirumab plus pembrolizumab in patients with previously treated advanced non-small-cell lung cancer, gastro-oesophageal cancer, or urothelial carcinomas (JVDF): a multicohort, n... von Herbst, Roy S, Prof, Arkenau, Hendrik-Tobias, MD, Santana-Davila, Rafael, MD, Calvo, Emiliano, MD, Paz-Ares, Luis, Prof, Cassier, Philippe A, MD, Bendell, Johanna, MD, Penel, Nicolas, Prof, Krebs, Matthew G, MD, Martin-Liberal, Juan, MD, Isambert, Nicolas, MD, Soriano, Andres, MD, Wermke, Martin, MD, Cultrera, Jennifer, MD, Gao, Ling, PhD, Widau, Ryan C, PhD, Mi, Gu, PhD, Jin, Jin, PhD, Ferry, David, MD, Fuchs, Charles S, Prof, Petrylak, Daniel P, Prof, Chau, Ian, MD

Volltext

Tumorigenicity and genetic profiling of circulating tumor cells in small-cell lung cancer von Hodgkinson, Cassandra L, Morrow, Christopher J, Li, Yaoyong, Metcalf, Robert L, Rothwell, Dominic G, Trapani, Francesca, Polanski, Radoslaw, Burt, Deborah J, Simpson, Kathryn L, Morris, Karen, Pepper, Stuart D, Nonaka, Daisuke, Greystoke, Alastair, Kelly, Paul, Bola, Becky, Krebs, Matthew G, Antonello, Jenny, Ayub, Mahmood, Faulkner, Suzanne, Priest, Lynsey, Carter, Louise, Tate, Catriona, Miller, Crispin J, Blackhall, Fiona, Brady, Ged, Dive, Caroline

Volltext

Evaluation and Prognostic Significance of Circulating Tumor Cells in Patients With Non–Small-Cell Lung Cancer von KREBS, Matthew G, SLOANE, Robert, RANSON, Malcolm, DIVE, Caroline, BLACKHALL, Fiona H, PRIEST, Lynsey, LANCASHIRE, Lee, HOU, Jian-Mei, GREYSTOKE, Alastair, WARD, Tim H, FERRALDESCHI, Roberta, HUGHES, Andrew, CLACK, Glen

Volltext

Clinical Significance and Molecular Characteristics of Circulating Tumor Cells and Circulating Tumor Microemboli in Patients With Small-Cell Lung Cancer von HOU, Jian-Mei, KREBS, Matthew G, WARD, Tim, BLACKHALL, Fiona H, DIVE, Caroline, LANCASHIRE, Lee, SLOANE, Robert, BACKEN, Alison, SWAIN, Rajeeb K, PRIEST, Lynsey J. C, GREYSTOKE, Alastair, CONG ZHOU, MORRIS, Karen

Volltext

Olaparib and durvalumab in patients with germline BRCA-mutated metastatic breast cancer (MEDIOLA): an open-label, multicentre, phase 1/2, basket study von Domchek, Susan M, Postel-Vinay, Sophie, Im, Seock-Ah, Park, Yeon Hee, Delord, Jean-Pierre, Italiano, Antoine, Alexandre, Jerome, You, Benoit, Bastian, Sara, Krebs, Matthew G, Wang, Ding, Waqar, Saiama N, Lanasa, Mark, Rhee, Joon, Gao, Haiyan, Rocher-Ros, Vidalba, Jones, Emma V, Gulati, Sakshi, Coenen-Stass, Anna, Kozarewa, Iwanka, Lai, Zhongwu, Angell, Helen K, Opincar, Laura, Herbolsheimer, Pia, Kaufman, Bella

Volltext

Utility of ctDNA to support patient selection for early phase clinical trials: the TARGET study von Rothwell, Dominic G., Ayub, Mahmood, Cook, Natalie, Thistlethwaite, Fiona, Carter, Louise, Dean, Emma, Smith, Nigel, Villa, Shaun, Dransfield, Joanne, Clipson, Alexandra, White, Daniel, Nessa, Kamrun, Ferdous, Saba, Howell, Matthew, Gupta, Avinash, Kilerci, Bedirhan, Mohan, Sumitra, Frese, Kris, Gulati, Sakshi, Miller, Crispin, Jordan, Allan, Eaton, Helen, Hickson, Nicholas, O’Brien, Ciara, Graham, Donna, Kelly, Claire, Aruketty, Sreeja, Metcalf, Robert, Chiramel, Jaseela, Tinsley, Nadina, Vickers, Alexander J., Kurup, Roopa, Frost, Hannah, Stevenson, Julie, Southam, Siobhan, Landers, Dónal, Wallace, Andrew, Marais, Richard, Hughes, Andrew M., Brady, Ged, Dive, Caroline, Krebs, Matthew G.

Volltext

Single-Agent Divarasib (GDC-6036) in Solid Tumors with a KRAS G12C Mutation von Sacher, Adrian, LoRusso, Patricia, Patel, Manish R., Miller, Wilson H., Garralda, Elena, Forster, Martin D., Santoro, Armando, Falcon, Alejandro, Kim, Tae Won, Paz-Ares, Luis, Bowyer, Samantha, de Miguel, Maria, Han, Sae-Won, Krebs, Matthew G., Lee, Jong-Seok, Cheng, Michael L., Arbour, Kathryn, Massarelli, Erminia, Choi, Yoonha, Shi, Zhen, Mandlekar, Sandhya, Lin, Mark T., Royer-Joo, Stephanie, Chang, Julie, Dharia, Neekesh V., Schutzman, Jennifer L., Desai, Jayesh

Volltext

Ramucirumab Plus Pembrolizumab in Patients with Previously Treated Advanced or Metastatic Biliary Tract Cancer: Nonrandomized, Open‐Label, Phase I Trial (JVDF) von Arkenau, Hendrik‐Tobias, Martin‐Liberal, Juan, Calvo, Emiliano, Penel, Nicolas, Krebs, Matthew G., Herbst, Roy S., Walgren, Richard A., Widau, Ryan C., Mi, Gu, Jin, Jin, Ferry, David, Chau, Ian

Volltext

Updated Integrated Analysis of the Efficacy and Safety of Entrectinib in Locally Advanced or Metastatic ROS1 Fusion-Positive Non-Small-Cell Lung Cancer von Dziadziuszko, Rafal, Krebs, Matthew G., De Braud, Filippo, Siena, Salvatore, Drilon, Alexander, Doebele, Robert C., Patel, Manish R., Cho, Byoung Chul, Liu, Stephen V., Ahn, Myung-Ju, Chiu, Chao-Hua, Farago, Anna F., Lin, Chia-Chi, Karapetis, Christos S., Li, Yu-Chung, Day, Bann-mo, Chen, David, Wilson, Timothy R., Barlesi, Fabrice

Volltext

Dose escalation and expansion cohorts in patients with advanced breast cancer in a Phase I study of the CDK7-inhibitor samuraciclib von Coombes, R. C., Howell, Sacha, Lord, Simon R., Kenny, Laura, Mansi, Janine, Mitri, Zahi, Palmieri, Carlo, Chap, Linnea I., Richards, Paul, Gradishar, William, Sardesai, Sagar, Melear, Jason, O’Shaughnessy, Joyce, Ward, Patrick, Chalasani, Pavani, Arkenau, Tobias, Baird, Richard D., Jeselsohn, Rinath, Ali, Simak, Clack, Glen, Bahl, Ashwani, McIntosh, Stuart, Krebs, Matthew G.

Volltext

Circulating Tumor Cells as a Window on Metastasis Biology in Lung Cancer von Hou, Jian-Mei, Krebs, Matthew, Ward, Tim, Sloane, Robert, Priest, Lynsey, Hughes, Andrew, Clack, Glen, Ranson, Malcolm, Blackhall, Fiona, Dive, Caroline

Volltext

Analysis of Circulating Tumor Cells in Patients with Non-small Cell Lung Cancer Using Epithelial Marker-Dependent and -Independent Approaches von Krebs, Matthew G., Hou, Jian-Mei, Sloane, Robert, Lancashire, Lee, Priest, Lynsey, Nonaka, Daisuke, Ward, Tim H., Backen, Alison, Clack, Glen, Hughes, Andrew, Ranson, Malcolm, Blackhall, Fiona H., Dive, Caroline

Volltext

Ceralasertib (AZD6738), an Oral ATR Kinase Inhibitor, in Combination with Carboplatin in Patients with Advanced Solid Tumors: A Phase I Study von Yap, Timothy A., Krebs, Matthew G., Postel-Vinay, Sophie, El-Khouiery, Anthony, Soria, Jean-Charles, Lopez, Juanita, Berges, Alienor, Cheung, S. Y. Amy, Irurzun-Arana, Itziar, Goldwin, Andrew, Felicetti, Brunella, Jones, Gemma N., Lau, Alan, Frewer, Paul, Pierce, Andrew J., Clack, Glen, Stephens, Christine, Smith, Simon A., Dean, Emma, Hollingsworth, Simon J.

Volltext

A cfDNA methylation-based tissue-of-origin classifier for cancers of unknown primary von Conway, Alicia-Marie, Pearce, Simon P., Clipson, Alexandra, Hill, Steven M., Chemi, Francesca, Slane-Tan, Dan, Ferdous, Saba, Hossain, A. S. Md Mukarram, Kamieniecka, Katarzyna, White, Daniel J., Mitchell, Claire, Kerr, Alastair, Krebs, Matthew G., Brady, Gerard, Dive, Caroline, Cook, Natalie, Rothwell, Dominic G.

Volltext

Long-Term Efficacy and Safety of Entrectinib in ROS1 Fusion–Positive NSCLC von Drilon, Alexander, Chiu, Chao-Hua, Fan, Yun, Cho, Byoung Chul, Lu, Shun, Ahn, Myung-Ju, Krebs, Matthew G., Liu, Stephen V., John, Thomas, Otterson, Gregory A., Tan, Daniel S.W., Patil, Tejas, Dziadziuszko, Rafal, Massarelli, Erminia, Seto, Takashi, Doebele, Robert C., Pitcher, Bethany, Kurtsikidze, Nino, Heinzmann, Sebastian, Siena, Salvatore

Volltext

Repotrectinib in ROS1 Fusion–Positive Non–Small-Cell Lung Cancer von Drilon, Alexander, Camidge, D. Ross, Lin, Jessica J., Kim, Sang-We, Solomon, Benjamin J., Dziadziuszko, Rafal, Besse, Benjamin, Goto, Koichi, de Langen, Adrianus Johannes, Wolf, Jürgen, Lee, Ki Hyeong, Popat, Sanjay, Springfeld, Christoph, Nagasaka, Misako, Felip, Enriqueta, Yang, Nong, Velcheti, Vamsidhar, Lu, Shun, Kao, Steven, Dooms, Christophe, Krebs, Matthew G., Yao, Wenxiu, Beg, Muhammad Shaalan, Hu, Xiufeng, Moro-Sibilot, Denis, Cheema, Parneet, Stopatschinskaja, Shanna, Mehta, Minal, Trone, Denise, Graber, Armin, Sims, Gregory, Yuan, Yong, Cho, Byoung Chul

Volltext

A biobank of small cell lung cancer CDX models elucidates inter- and intratumoral phenotypic heterogeneity von Simpson, Kathryn L., Stoney, Ruth, Frese, Kristopher K., Simms, Nicole, Rowe, William, Pearce, Simon P., Humphrey, Sam, Booth, Laura, Morgan, Derrick, Dynowski, Marek, Trapani, Francesca, Catozzi, Alessia, Revill, Mitchell, Helps, Thomas, Galvin, Melanie, Girard, Luc, Nonaka, Daisuke, Carter, Louise, Krebs, Matthew G., Cook, Natalie, Carter, Mathew, Priest, Lynsey, Kerr, Alastair, Gazdar, Adi F., Blackhall, Fiona, Dive, Caroline

Volltext