Treatment of high-grade glioma in children and adolescents von MacDonald, T. J., Aguilera, D., Kramm, C. M.

Volltext

Optimized human CYP4B1 in combination with the alkylator prodrug 4-ipomeanol serves as a novel suicide gene system for adoptive T-cell therapies von Roellecke, K, Virts, E L, Einholz, R, Edson, K Z, Altvater, B, Rossig, C, von Laer, D, Scheckenbach, K, Wagenmann, M, Reinhardt, D, Kramm, C M, Rettie, A E, Wiek, C, Hanenberg, H

Volltext

The Bowel Function Index for Evaluating Constipation in Pain Patients: Definition of a Reference Range for a Non-Constipated Population of Pain Patients von Ueberall, MA, Müller-Lissner, S, Buschmann-Kramm, C, Bosse, B

Volltext

Nimotuzumab and radiotherapy for treatment of newly diagnosed diffuse intrinsic pontine glioma (DIPG): a phase III clinical study von Fleischhack, G., Massimino, M., Warmuth-Metz, M., Khuhlaeva, E., Janssen, G., Graf, N., Rutkowski, S., Beilken, A., Schmid, I., Biassoni, V., Gorelishev, S. K., Kramm, C., Reinhard, H., Schlegel, P. G., Kortmann, R.-D., Reuter, D., Bach, F., Iznaga-Escobar, N. E., Bode, U.

Volltext

Genomic profiling of Acute lymphoblastic leukemia in ataxia telangiectasia patients reveals tight link between ATM mutations and chromothripsis von Ratnaparkhe, M, Hlevnjak, M, Kolb, T, Jauch, A, Maass, K K, Devens, F, Rode, A, Hovestadt, V, Korshunov, A, Pastorczak, A, Mlynarski, W, Sungalee, S, Korbel, J, Hoell, J, Fischer, U, Milde, T, Kramm, C, Nathrath, M, Chrzanowska, K, Tausch, E, Takagi, M, Taga, T, Constantini, S, Loeffen, J, Meijerink, J, Zielen, S, Gohring, G, Schlegelberger, B, Maass, E, Siebert, R, Kunz, J, Kulozik, A E, Worst, B, Jones, D T, Pfister, S M, Zapatka, M, Lichter, P, Ernst, A

Volltext

MR Imaging and Clinical Characteristics of Diffuse Glioneuronal Tumor with Oligodendroglioma-like Features and Nuclear Clusters von Benesch, M, Perwein, T, Apfaltrer, G, Langer, T, Neumann, A, Brecht, I B, Schuhmann, M U, Cario, H, Frühwald, M C, Vollert, K, van Buiren, M, Deng, M Y, Seitz, A, Haberler, C, Mynarek, M, Kramm, C, Sahm, F, Robe, P A, Dankbaar, J W, Hoff, K V, Warmuth-Metz, M, Bison, B

Volltext

Cerebellar location may predict an unfavourable prognosis in paediatric high-grade glioma von Karremann, M, Rausche, U, Roth, D, Kühn, A, Pietsch, T, Gielen, G H, Warmuth-Metz, M, Kortmann, R-D, Straeter, R, Gnekow, A, Wolff, J E A, Kramm, C M

Volltext

Phase II open-label, global study evaluating dabrafenib in combination with trametinib in pediatric patients with BRAF V600-mutant high-grade glioma (HGG) or low-grade glioma (LGG) von Hargrave, D, Witt, O, Cohen, K, Packer, R, Lissat, A, Kordes, U, Laetsch, T W, Hoffman, L, Lassaletta, A, Gerber, N U, Gilheeney, S, Holm, S, Kramm, C, Sumerauer, D, Reitmann, C, Russo, M W, Bouffet, E

Volltext

Targeted expression of human folylpolyglutamate synthase for selective enhancement of methotrexate chemotherapy in osteosarcoma cells von Bienemann, K, Staege, M S, Howe, S J, Sena-Esteves, M, Hanenberg, H, Kramm, C M

Volltext

Serum cystatin C is a suitable marker for routine monitoring of renal function in pediatric cancer patients, especially of very young age von Lankisch, P., Wessalowski, R., Maisonneuve, P., Haghgu, M., Hermsen, D., Kramm, C.M.

Volltext

Thalamic high-grade gliomas in children: a distinct clinical subset? von Kramm, Christof M., Butenhoff, Sandra, Rausche, Ulrike, Warmuth-Metz, Monika, Kortmann, Rolf-Dieter, Pietsch, Torsten, Gnekow, Astrid, Jorch, Norbert, Janssen, Gisela, Berthold, Frank, Wolff, Johannes E.

Volltext

Craniospinal irradiation with concurrent temozolomide for primary metastatic pediatric high-grade or diffuse intrinsic pontine gliomas: A first report from the GPOH-HIT-HGG Study G... von Müller, K., Schlamann, A., Guckenberger, M., Warmuth-Metz, M., Glück, A., Pietschmann, S., Wawer, A., Kortmann, R.-D., Kramm, C., von Bueren, A.O.

Volltext

Mechanisms of thymidine kinase ganciclovir and cytosine deaminase 5-fluorocytosine suicide gene therapy-induced cell death in glioma cells von Fischer, Ute, Steffens, Sabine, Frank, Susanne, Rainov, Nikolai G, Schulze-Osthoff, Klaus, Kramm, Christof M

Volltext

Craniospinal irradiation with concurrent temozolomide and nimotuzumab in a child with primary metastatic diffuse intrinsic pontine glioma: A compassionate use treatment von Müller, K., Schlamann, A., Seidel, C., Warmuth-Metz, M., Christiansen, H., Vordermark, D., Kortmann, R.-D., Kramm, C.M., von Bueren, A.O.

Volltext

Synergistic Anticancer Effects of Ganciclovir/Thymidine Kinase and 5-Fluorocytosine/Cytosine Deaminase Gene Therapies von Aghi, Manish, Cho, Ting-Chao, Chiocca, E. Antonio, Kramm, Christof M., Breakefield, Xandra O.

Volltext

Therapeutic efficiency and safety of a second-generation replication-conditional HSV1 vector for brain tumor gene therapy von Kramm, C M, Chase, M, Herrlinger, U, Jacobs, A, Pechan, P A, Rainov, N G, Sena-Esteves, M, Aghi, M, Barnett, F H, Chiocca, E A, Breakefield, X O

Volltext

Immune recovery in children undergoing allogeneic stem cell transplantation: absolute CD8 CD3 count reconstitution is associated with survival von KOEHL, U, BOCHENNEK, K, ORTH, A, BADER, P, SCHWABE, D, KLINGEBIEL, T, ZIMMERMANN, S. Y, LEHRNBECHER, T, SÖRENSEN, J, ESSER, R, ANDREAS, C, KRAMM, C, GRÜTTNER, H. P, FALKENBERG, E

Volltext

Combined Trimethoprim and Caspofungin Treatment for Severe Pneumocystis Jiroveci Pneumonia in a Five Year Old Boy with Acute Lymphoblastic Leukemia von Beltz, K., Kramm, C. M., Laws, H.-J., Schroten, H., Wessalowski, R., Göbel, U.

Volltext

Immune response induced by retrovirus-mediated HSV-tk/GCV pharmacogene therapy in patients with glioblastoma multiforme von RAINOV, N. G, KRAMM, C. M, BANNING, U, RIEMANN, D, HOLZHAUSEN, H-J, HEIDECKE, V, BURGER, K. J, BURKERT, W, KÖRHOLZ, D

Volltext

Allogeneic and autologous stem-cell transplantation in advanced Ewing tumors: An update after long-term follow-up from two centers of the European Intergroup Study EICESS von BURDACH, S, VAN KAICK, B, ENGEL, B, DIRKSEN, U, KRAMM, C, NÜRNBERGER, W, HEYLL, A, LADENSTEIN, R, GADNER, H, JÜRGENS, H, GÖBEL, U, LAWS, H. J, AHRENS, S, HAASE, R, KÖRHOLZ, D, PAPE, H, DUNST, J, KAHN, T, WILLERS, R

Volltext