Src activation regulates anoikis in human colon tumor cell lines von WINDHAM, T. Christopher, PARIKH, Nila U, SIWAK, Doris R, SUMMY, Justin M, MCCONKEY, David J, KRAKER, Alan J, GALLICK, Gary E

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Roles of activated Src and Stat3 signaling in melanoma tumor cell growth von Niu, Guilian, Bowman, Tammy, Huang, Mei, Shivers, Steve, Reintgen, Douglas, Daud, Adil, Chang, Alfred, Kraker, Alan, Jove, Richard, Yu, Hua

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Gemcitabine sensitization by checkpoint kinase 1 inhibition correlates with inhibition of a Rad51 DNA damage response in pancreatic cancer cells von Parsels, Leslie A, Morgan, Meredith A, Tanska, Daria M, Parsels, Joshua D, Palmer, Brian D, Booth, R John, Denny, William A, Canman, Christine E, Kraker, Alan J, Lawrence, Theodore S, Maybaum, Jonathan

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Constitutive activation of Stat3 by the Src and JAK tyrosine kinases participates in growth regulation of human breast carcinoma cells von GARCIA, Roy, BOWMAN, Tammy L, LAUDANO, Andy, GAZIT, Aviv, LEVITZKI, Alexander, KRAKER, Alan, JOVE, Richard, NIU GUILLIAN, HUA YU, MINTON, Sue, MURO-CACHO, Carlos A, COX, Charles E, FALCONE, Robert, FAIRCLOUGH, Rita, PARSONS, Sarah

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4-Phenylpyrrolo[3,4-c]carbazole-1,3(2H,6H)-dione Inhibitors of the Checkpoint Kinase Wee1. Structure−Activity Relationships for Chromophore Modification and Phenyl Ring Substitutio... von Palmer, Brian D, Thompson, Andrew M, Booth, R. John, Dobrusin, Ellen M, Kraker, Alan J, Lee, Ho H, Lunney, Elizabeth A, Mitchell, Lorna H, Ortwine, Daniel F, Smaill, Jeff B, Swan, Leesa M, Denny, William A

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A Novel Pyridopyrimidine Inhibitor of Abl Kinase Is a Picomolar Inhibitor of Bcr-abl-driven K562 Cells and Is Effective against STI571-resistant Bcr-abl Mutants von HURON, David R, GORRE, Mercedes E, KRAKER, Alan J, SAWYERS, Charles L, ROSEN, Neal, MOASSER, Mark M

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A Specific Inhibitor of the Epidermal Growth Factor Receptor Tyrosine Kinase von Fry, David W., Kraker, Alan J., McMichael, Amy, Ambroso, Linda A., Nelson, James M., Leopold, Wilbur R., Conners, Richard W., Bridges, Alexander J.

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Biochemical and cellular effects of c-Src kinase-selective pyrido[2,3- d]pyrimidine tyrosine kinase inhibitors von Kraker, Alan J, Hartl, Brian G, Amar, Aneesa M, Barvian, Mark R, Showalter, H.D.Hollis, Moore, Charles W

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Inhibition of Src kinases by a selective tyrosine kinase inhibitor causes mitotic arrest von MOASSER, M. M, SRETHAPAKDI, M, SACHAR, K. S, KRAKER, A. J, ROSEN, N

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Activation of Stat3 in v-Src-transformed Fibroblasts Requires Cooperation of Jak1 Kinase Activity von Zhang, Yi, Turkson, James, Carter-Su, Christin, Smithgall, Thomas, Levitzki, Alexander, Kraker, Alan, Krolewski, John J., Medveczky, Peter, Jove, Richard

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Modulation of Histone Acetylation by [4-(Acetylamino)-N-(2-Amino-phenyl) Benzamide] in HCT-8 Colon Carcinoma von Kraker, Alan J, Mizzen, Craig A, Hartl, Brian G, Miin, Johnson, Allis, C David, Merriman, Ronald L

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Inhibition of Bcr-Abl kinase activity by PD180970 blocks constitutive activation of Stat5 and growth of CML cells von MEI HUANG, DORSEY, Jay F, HUA YU, MOSCINSKI, Lynn, SHENG WEI, DJEU, Julie, DALTON, William S, BHALLA, Kapil, LOUGHRAN, Thomas P, JIE WU, JOVE, Richard, EPLING-BURNETTE, P. K, NIMMANAPALLI, Ramadevi, LANDOWSKI, Terry H, MORA, Linda B, NIU, Guilian, SINIBALDI, Dominic, FANQI BAI, KRAKER, Alan

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Tyrosine Kinase Inhibitors. 8. An Unusually Steep Structure−Activity Relationship for Analogues of 4-(3-Bromoanilino)-6,7-dimethoxyquinazoline (PD 153035), a Potent Inhibitor of th... von Bridges, Alexander J, Zhou, Hairong, Cody, Donna R, Rewcastle, Gordon W, McMichael, Amy, Showalter, H. D. Hollis, Fry, David W, Kraker, Alan J, Denny, William A

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Src Family Kinases Phosphorylate Protein Kinase C δ on Tyrosine Residues and Modify the Neoplastic Phenotype of Skin Keratinocytes von Joseloff, Elizabeth, Cataisson, Christophe, Aamodt, Heather, Ocheni, Henrietta, Blumberg, Peter, Kraker, Alan J., Yuspa, Stuart H.

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Synthesis and structure–activity relationships of soluble 8-substituted 4-(2-chlorophenyl)-9-hydroxypyrrolo[3,4- c]carbazole-1,3(2 H,6 H)-diones as inhibitors of the Wee1 and Chk1... von Smaill, Jeff B., Lee, Ho H., Palmer, Brian D., Thompson, Andrew M., Squire, Christopher J., Baker, Edward N., Booth, R. John, Kraker, Alan, Hook, Ken, Denny, William A.

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Synthesis and structure–activity relationships of N-6 substituted analogues of 9-hydroxy-4-phenylpyrrolo[3,4- c]carbazole-1,3(2 H,6 H)-diones as inhibitors of Wee1 and Chk1 checkpo... von Smaill, Jeff B., Baker, Edward N., Booth, R. John, Bridges, Alexander J., Dickson, James M., Dobrusin, Ellen M., Ivanovic, Ivan, Kraker, Alan J., Lee, Ho H., Lunney, Elizabeth A., Ortwine, Daniel F., Palmer, Brian D., Quin, John, Squire, Christopher J., Thompson, Andrew M., Denny, William A.

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Tyrosine Kinase Inhibitors. 9. Synthesis and Evaluation of Fused Tricyclic Quinazoline Analogues as ATP Site Inhibitors of the Tyrosine Kinase Activity of the Epidermal Growth Fact... von Rewcastle, Gordon W, Palmer, Brian D, Bridges, Alexander J, Showalter, H. D. Hollis, Sun, Li, Nelson, James, McMichael, Amy, Kraker, Alan J, Fry, David W, Denny, William A

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Structure−Activity Relationships for a Novel Series of Pyrido[2,3-d]pyrimidine Tyrosine Kinase Inhibitors von Hamby, James M, Connolly, Cleo J. C, Schroeder, Mel C, Winters, R. Thomas, Showalter, H. D. Hollis, Panek, Robert L, Major, Terry C, Olsewski, Bronislawa, Ryan, Michael J, Dahring, Tawny, Lu, Gina H, Keiser, Joan, Amar, Aneesa, Shen, Cindy, Kraker, Alan J, Slintak, Veronika, Nelson, James M, Fry, David W, Bradford, Laura, Hallak, Hussein, Doherty, Annette M

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Inhibitors of tyrosine kinase von Klohs, Wayne D, Fry, David W, Kraker, Alan J

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Role of Tyrosine Kinase Activity of Epidermal Growth Factor Receptor in the Lysophosphatidic Acid-stimulated Mitogen-activated Protein Kinase Pathway von Cunnick, Jess M., Dorsey, Jay F., Standley, Todd, Turkson, James, Kraker, Alan J., Fry, David W., Jove, Richard, Wu, Jie

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