Voltage sensor interaction site for selective small molecule inhibitors of voltage-gated sodium channels von McCormack, Ken, Santos, Sonia, Chapman, Mark L, Krafte, Douglas S, Marron, Brian E, West, Christopher W, Krambis, Michael J, Antonio, Brett M, Zellmer, Shannon G, Printzenhoff, David, Padilla, Karen M, Lin, Zhixin, Wagoner, P Kay, Swain, Nigel A, Stupple, Paul A, de Groot, Marcel, Butt, Richard P, Castle, Neil A

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A comprehensive approach to identifying repurposed drugs to treat SCN8A epilepsy von Atkin, Talia A., Maher, Chani M., Gerlach, Aaron C., Gay, Bryant C., Antonio, Brett M., Santos, Sonia C., Padilla, Karen M., Rader, JulieAnn, Krafte, Douglas S., Fox, Matthew A., Stewart, Gregory R., Petrovski, Slavé, Devinsky, Orrin, Might, Matthew, Petrou, Steven, Goldstein, David B.

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A-803467, a potent and selective Nav1.8 sodium channel blocker, attenuates neuropathic and inflammatory pain in the rat von Jarvis, Michael F, Honore, Prisca, Shieh, Char-Chang, Chapman, Mark, Joshi, Shailen, Zhang, Xu-Feng, Kort, Michael, Carroll, William, Marron, Brian, Atkinson, Robert, Thomas, James, Liu, Dong, Krambis, Michael, Liu, Yi, McGaraughty, Steve, Chu, Katharine, Roeloffs, Rosemarie, Zhong, Chengmin, Mikusa, Joseph P, Hernandez, Gricelda, Gauvin, Donna, Wade, Carrie, Zhu, Chang, Pai, Madhavi, Scanio, Marc, Shi, Lei, Drizin, Irene, Gregg, Robert, Matulenko, Mark, Hakeem, Ahmed, Gross, Michael, Johnson, Matthew, Marsh, Kennan, Wagoner, P. Kay, Sullivan, James P, Faltynek, Connie R, Krafte, Douglas S

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A-887826 is a structurally novel, potent and voltage-dependent Na(v)1.8 sodium channel blocker that attenuates neuropathic tactile allodynia in rats von Zhang, Xu-Feng, Shieh, Char-Chang, Chapman, Mark L, Matulenko, Mark A, Hakeem, Ahmed H, Atkinson, Robert N, Kort, Michael E, Marron, Brian E, Joshi, Shailen, Honore, Prisca, Faltynek, Connie R, Krafte, Douglas S, Jarvis, Michael F

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Sodium channels and nociception: recent concepts and therapeutic opportunities von Krafte, Douglas S, Bannon, Anthony W

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Discovery and Biological Evaluation of 5-Aryl-2-furfuramides, Potent and Selective Blockers of the Nav1.8 Sodium Channel with Efficacy in Models of Neuropathic and Inflammatory Pai... von Kort, Michael E, Drizin, Irene, Gregg, Robert J, Scanio, Marc J. C, Shi, Lei, Gross, Michael F, Atkinson, Robert N, Johnson, Matthew S, Pacofsky, Gregory J, Thomas, James B, Carroll, William A, Krambis, Michael J, Liu, Dong, Shieh, Char-Chang, Zhang, XuFeng, Hernandez, Gricelda, Mikusa, Joseph P, Zhong, Chengmin, Joshi, Shailen, Honore, Prisca, Roeloffs, Rosemarie, Marsh, Kennan C, Murray, Bernard P, Liu, Jinrong, Werness, Stephen, Faltynek, Connie R, Krafte, Douglas S, Jarvis, Michael F, Chapman, Mark L, Marron, Brian E

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Discovery and biological evaluation of potent, selective, orally bioavailable, pyrazine-based blockers of the Na(v)1.8 sodium channel with efficacy in a model of neuropathic pain von Scanio, Marc J C, Shi, Lei, Drizin, Irene, Gregg, Robert J, Atkinson, Robert N, Thomas, James B, Johnson, Matthew S, Chapman, Mark L, Liu, Dong, Krambis, Michael J, Liu, Yi, Shieh, Char-Chang, Zhang, Xufeng, Simler, Gricelda H, Joshi, Shailen, Honore, Prisca, Marsh, Kennan C, Knox, Alison, Werness, Stephen, Antonio, Brett, Krafte, Douglas S, Jarvis, Michael F, Faltynek, Connie R, Marron, Brian E, Kort, Michael E

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Discovery and biological evaluation of potent, selective, orally bioavailable, pyrazine-based blockers of the Nav1.8 sodium channel with efficacy in a model of neuropathic pain von SCANIO, Marc J. C, LEI SHI, YI LIU, SHIEH, Char-Chang, XUFENG ZHANG, SIMLER, Gricelda H, JOSHI, Shailen, HONORE, Prisca, MARSH, Kennan C, KNOX, Alison, WERNESS, Stephen, ANTONIO, Brett, DRIZIN, Irene, KRAFTE, Douglas S, JARVIS, Michael F, FALTYNEK, Connie R, MARRON, Brian E, KORT, Michael E, GREGG, Robert J, ATKINSON, Robert N, THOMAS, James B, JOHNSON, Matthew S, CHAPMAN, Mark L, DONG LIU, KRAMBIS, Michael J

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Subtype-selective Na(v)1.8 sodium channel blockers: identification of potent, orally active nicotinamide derivatives von Kort, Michael E, Atkinson, Robert N, Thomas, James B, Drizin, Irene, Johnson, Matthew S, Secrest, Matthew A, Gregg, Robert J, Scanio, Marc J C, Shi, Lei, Hakeem, Ahmed H, Matulenko, Mark A, Chapman, Mark L, Krambis, Michael J, Liu, Dong, Shieh, Char-Chang, Zhang, XuFeng, Simler, Gricelda, Mikusa, Joseph P, Zhong, Chengmin, Joshi, Shailen, Honore, Prisca, Roeloffs, Rosemarie, Werness, Stephen, Antonio, Brett, Marsh, Kennan C, Faltynek, Connie R, Krafte, Douglas S, Jarvis, Michael F, Marron, Brian E

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Block of Nav1.8 by Small Molecules von Krafte, Douglas S., Chapman, Mark, Marron, Brian, Atkinson, Robert, Liu, Yi, Yu, Fei, Kort, Michael, Jarvis, Michael F.

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The Effect of κ-Opioid Receptor Agonists on Tetrodotoxin-Resistant Sodium Channels in Primary Sensory Neurons von Su, Xin, Castle, Neil A., Antonio, Brett, Roeloffs, Rosemarie, Thomas, James B., Krafte, Douglas S., Chapman, Mark L.

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Direct Activation of an Inwardly Rectifying Potassium Channel by Arachidonic Acid von Liu, Y, Liu, D, Heath, L, Meyers, D M, Krafte, D S, Wagoner, P K, Silvia, C P, Yu, W, Curran, M E

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Tenidap, a novel anti-inflammatory agent, is an opener of the inwardly rectifying K + channel hKir2.3 von Liu, Yi, Liu, Dong, Printzenhoff, David, Coghlan, Michael J., Harris, Richard, Krafte, Douglas S.

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Decrease of inward rectification as a mechanism for arachidonic acid-induced potentiation of hKir2.3 von Liu, Yi, Liu, Dong, Krafte, Douglas S

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A comprehensive approach to identifying repurposed drugs to treat SCN 8A epilepsy von Atkin, Talia A., Maher, Chani M., Gerlach, Aaron C., Gay, Bryant C., Antonio, Brett M., Santos, Sonia C., Padilla, Karen M., Rader, JulieAnn, Krafte, Douglas S., Fox, Matthew A., Stewart, Gregory R., Petrovski, Slavé, Devinsky, Orrin, Might, Matthew, Petrou, Steven, Goldstein, David B.

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Synthesis and Structure-Activity Relationships of 6-Heterocyclic-Substituted Purines as Inactivation Modifiers of Cardiac Sodium Channels von Estep, Kimberly G, Josef, Kurt A, Bacon, Edward R, Carabateas, Philip M, Rumney, Squire, Pilling, Garry M, Krafte, Douglas S, Volberg, Walter A, Dillon, Kathleen, Dugrenier, Nancy, Briggs, G. Maurice, Canniff, Paul C, Gorczyca, William P, Stankus, Gerald P, Ezrin, Alan M

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A-887826 is a structurally novel, potent and voltage-dependent Nav1.8 sodium channel blocker that attenuates neuropathic tactile allodynia in rats von Zhang, Xu-Feng, Shieh, Char-Chang, Chapman, Mark L., Matulenko, Mark A., Hakeem, Ahmed H., Atkinson, Robert N., Kort, Michael E., Marron, Brian E., Joshi, Shailen, Honore, Prisca, Faltynek, Connie R., Krafte, Douglas S., Jarvis, Michael F.

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Novel Inhibitors of Potassium Ion Channels on Human T Lymphocytes von Michne, William F, Guiles, Joseph W, Treasurywala, Adi M, Castonguay, Laurie A, Weigelt, Carolyn A, Oconnor, Bernard, Volberg, Walter A, Grant, Alison M, Chadwick, Christopher C, Krafte, Douglas S, Hill, Roger J

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Subtype-selective Na sub(v)1.8 sodium channel blockers: Identification of potent, orally active nicotinamide derivatives von Faltynek, Connie R, Krafte, Douglas S, Jarvis, Michael F, Marron, Brian E

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Voltage Dependence of Cardiac Delayed Rectifier Block by Methanesulfonamide Class III Antiarrhythmic Agents von Krafte, Douglas S, Volberg, Walter A

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