Why Hydroxamates May Not Be the Best Histone Deacetylase Inhibitors-What Some May Have Forgotten or Would Rather Forget? von Shen, Sida, Kozikowski, Alan P.

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Rational Design and Simple Chemistry Yield a Superior, Neuroprotective HDAC6 Inhibitor, Tubastatin A von Butler, Kyle V, Kalin, Jay, Brochier, Camille, Vistoli, Guilio, Langley, Brett, Kozikowski, Alan P

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Indole-2-carboxamide-based MmpL3 Inhibitors Show Exceptional Antitubercular Activity in an Animal Model of Tuberculosis Infection von Stec, Jozef, Onajole, Oluseye K, Lun, Shichun, Guo, Haidan, Merenbloom, Benjamin, Vistoli, Giulio, Bishai, William R, Kozikowski, Alan P

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HDAC6 inhibitors reverse axonal loss in a mouse model of mutant HSPB1–induced Charcot-Marie-Tooth disease von d'Ydewalle, Constantin, Krishnan, Jyothsna, Chiheb, Driss M, Van Damme, Philip, Irobi, Joy, Kozikowski, Alan P, Berghe, Pieter Vanden, Timmerman, Vincent, Robberecht, Wim, Van Den Bosch, Ludo

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Selective Histone Deacetylase 6 Inhibitors Bearing Substituted Urea Linkers Inhibit Melanoma Cell Growth von Bergman, Joel A, Woan, Karrune, Perez-Villarroel, Patricio, Villagra, Alejandro, Sotomayor, Eduardo M, Kozikowski, Alan P

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HDAC6 is a therapeutic target in mutant GARS-induced Charcot-Marie-Tooth disease von Benoy, Veronick, Van Helleputte, Lawrence, Prior, Robert, d'Ydewalle, Constantin, Haeck, Wanda, Geens, Natasja, Scheveneels, Wendy, Schevenels, Begga, Cader, M Zameel, Talbot, Kevin, Kozikowski, Alan P, Vanden Berghe, Pieter, Van Damme, Philip, Robberecht, Wim, Van Den Bosch, Ludo

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Mercaptoacetamide: A promising zinc-binding group for the discovery of selective histone deacetylase 6 inhibitors von Tavares, Maurício T., Kozikowski, Alan P., Shen, Sida

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Structure−Activity Relationships for a Series of Quinoline-Based Compounds Active against Replicating and Nonreplicating Mycobacterium tuberculosis von Lilienkampf, Annamaria, Mao, Jialin, Wan, Baojie, Wang, Yuehong, Franzblau, Scott G, Kozikowski, Alan P

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Histone/protein deacetylase 11 targeting promotes Foxp3+ Treg function von Huang, Jianbing, Wang, Liqing, Dahiya, Satinder, Beier, Ulf H., Han, Rongxiang, Samanta, Arabinda, Bergman, Joel, Sotomayor, Eduardo M., Seto, Edward, Kozikowski, Alan P., Hancock, Wayne W.

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Epigenetic Regulation of Autophagy by the Methyltransferase G9a von Artal-Martinez de Narvajas, Amaia, Gomez, Timothy S., Zhang, Jin-San, Mann, Alexander O., Taoda, Yoshiyuki, Gorman, Jacquelyn A., Herreros-Villanueva, Marta, Gress, Thomas M., Ellenrieder, Volker, Bujanda, Luis, Kim, Do-Hyung, Kozikowski, Alan P., Koenig, Alexander, Billadeau, Daniel D.

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Glycogen Synthase Kinase-3 Inhibition Sensitizes Pancreatic Cancer Cells to Chemotherapy by Abrogating the TopBP1/ATR-Mediated DNA Damage Response von Ding, Li, Madamsetty, Vijay S, Kiers, Spencer, Alekhina, Olga, Ugolkov, Andrey, Dube, John, Zhang, Yu, Zhang, Jin-San, Wang, Enfeng, Dutta, Shamit K, Schmitt, Daniel M, Giles, Francis J, Kozikowski, Alan P, Mazar, Andrew P, Mukhopadhyay, Debabrata, Billadeau, Daniel D

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A selective histone deacetylase-6 inhibitor improves BDNF trafficking in hippocampal neurons from Mecp2 knockout mice: implications for Rett syndrome von Xu, Xin, Kozikowski, Alan P, Pozzo-Miller, Lucas

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Histone Deacetylase 6 and Heat Shock Protein 90 Control the Functions of Foxp3+ T-Regulatory Cells von de Zoeten, Edwin F., Wang, Liqing, Butler, Kyle, Beier, Ulf H., Akimova, Tatiana, Sai, Hong, Bradner, James E., Mazitschek, Ralph, Kozikowski, Alan P., Matthias, Patrick, Hancock, Wayne W.

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Development of Small Molecules that Specifically Inhibit the D‑loop Activity of RAD51 von Lv, Wei, Budke, Brian, Pawlowski, Michal, Connell, Philip P, Kozikowski, Alan P

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Structural and in Vivo Characterization of Tubastatin A, a Widely Used Histone Deacetylase 6 Inhibitor von Shen, Sida, Svoboda, Michal, Zhang, Guangming, Cavasin, Maria A, Motlova, Lucia, McKinsey, Timothy A, Eubanks, James H, Bařinka, Cyril, Kozikowski, Alan P

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Discovery of a New Isoxazole-3-hydroxamate-Based Histone Deacetylase 6 Inhibitor SS-208 with Antitumor Activity in Syngeneic Melanoma Mouse Models von Shen, Sida, Hadley, Melissa, Ustinova, Kseniya, Pavlicek, Jiri, Knox, Tessa, Noonepalle, Satish, Tavares, Mauricio T, Zimprich, Chad A, Zhang, Guiping, Robers, Matthew B, Bařinka, Cyril, Kozikowski, Alan P, Villagra, Alejandro

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Preliminary Structure–Activity Relationships and Biological Evaluation of Novel Antitubercular Indolecarboxamide Derivatives Against Drug-Susceptible and Drug-Resistant Mycobacteri... von Onajole, Oluseye K, Pieroni, Marco, Tipparaju, Suresh K, Lun, Shichun, Stec, Jozef, Chen, Gang, Gunosewoyo, Hendra, Guo, Haidan, Ammerman, Nicole C, Bishai, William R, Kozikowski, Alan P

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Indoleamides are active against drug-resistant Mycobacterium tuberculosis von Lun, Shichun, Guo, Haidan, Onajole, Oluseye K., Pieroni, Marco, Gunosewoyo, Hendra, Chen, Gang, Tipparaju, Suresh K., Ammerman, Nicole C., Kozikowski, Alan P., Bishai, William R.

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Synergistic Interactions of Indole-2-Carboxamides and β-Lactam Antibiotics against Mycobacterium abscessus von Raynaud, Clément, Daher, Wassim, Roquet-Banères, Françoise, Johansen, Matt D, Stec, Jozef, Onajole, Oluseye K, Ordway, Diane, Kozikowski, Alan P, Kremer, Laurent

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Use of the Nitrile Oxide Cycloaddition (NOC) Reaction for Molecular Probe Generation: A New Class of Enzyme Selective Histone Deacetylase Inhibitors (HDACIs) Showing Picomolar Acti... von Kozikowski, Alan P, Tapadar, Subhasish, Luchini, Doris N, Kim, Ki Hwan, Billadeau, Daniel D

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