CYP450 phenotyping and accurate mass identification of metabolites of the 8-aminoquinoline, anti-malarial drug primaquine von Pybus, Brandon S, Sousa, Jason C, Jin, Xiannu, Ferguson, James A, Christian, Robert E, Barnhart, Rebecca, Vuong, Chau, Sciotti, Richard J, Reichard, Gregory A, Kozar, Michael P, Walker, Larry A, Ohrt, Colin, Melendez, Victor

Volltext

Statistical Prediction of Integrated Kinetic Energy in North Atlantic Tropical Cyclones von Kozar, Michael E, Misra, Vasubandhu

Volltext

Hindcasts of Integrated Kinetic Energy in Atlantic Tropical Cyclones: A Neural Network Prediction Scheme von Kozar, Michael E., Misra, Vasubandhu, Powell, Mark D.

Volltext

Evaluation of twentieth-century Atlantic Warm Pool simulations in historical CMIP5 runs von Kozar, Michael E., Misra, Vasubandhu

Volltext

Nanoparticle formulations of decoquinate increase antimalarial efficacy against liver stage Plasmodium infections in mice von Wang, Hongxing, MD, Li, Qigui, PhD, Reyes, Sean, BSc, Zhang, Jing, BSc, Zeng, Qiang, MSc, Zhang, Ping, BSc, Xie, Lisa, PhD, Lee, Patricia J., BSc, Roncal, Norma, MSc, Melendez, Victor, PhD, Hickman, Mark, PhD, Kozar, Michael P., PhD

Volltext

Antimalarial Activity of Novel 5-Aryl-8-Aminoquinoline Derivatives von Shiraki, Hiroaki, Kozar, Michael P, Melendez, Victor, Hudson, Thomas H, Ohrt, Colin, Magill, Alan J, Lin, Ai J

Volltext

Stratified statistical models of North Atlantic basin-wide and regional tropical cyclone counts von Kozar, Michael E., Mann, Michael E., Camargo, Suzana J., Kossin, James P., Evans, Jenni L.

Volltext

Synthesis and Antimalarial Activity of 2-Guanidino-4-oxoimidazoline Derivatives von Liu, Xianjun, Wang, Xihong, Li, Qigui, Kozar, Michael P, Melendez, Victor, O’Neil, Michael T, Lin, Ai J

Volltext

Causal Prophylactic Efficacy of Primaquine, Tafenoquine, and Atovaquone-Proguanil Against Plasmodium cynomolgi in a Rhesus Monkey Model von DiTusa, Charles, Kozar, Michael P, Pybus, Brandon, Sousa, Jason, Berman, Jonathan, Gettayacamin, Montip, Im-erbsin, Rawiwan, Tungtaeng, Anchalee, Ohrt, Colin

Volltext

New imidazolidinedione derivatives as antimalarial agents von Zhang, Liang, Sathunuru, Ramadas, Luong, ThuLan, Melendez, Victor, Kozar, Michael P., Lin, Ai J.

Volltext

Antimalarial Activities of New Guanidylimidazole and Guanidylimidazoline Derivatives von Zhang, Liang, Sathunuru, Ramadas, Caridha, Diana, Pybus, Brandon, O’Neil, Michael T, Kozar, Michael P, Lin, Ai J

Volltext

Long-term variations of North Atlantic tropical cyclone activity downscaled from a coupled model simulation of the last millennium von Kozar, Michael E., Mann, Michael E., Emanuel, Kerry A., Evans, Jenni L.

Volltext

Formulation and Particle Size Reduction Improve Bioavailability of Poorly Water-Soluble Compounds with Antimalarial Activity von Wang, Hongxing, Li, Qigui, Reyes, Sean, Zhang, Jing, Xie, Lisa, Melendez, Victor, Hickman, Mark, Kozar, Michael P.

Volltext

In Vitro Metabolism of Phenoxypropoxybiguanide Analogues in Human Liver Microsomes to Potent Antimalarial Dihydrotriazines von Shearer, Todd. W, Kozar, Michael. P, O'Neil, Michael T, Smith, Philip L, Schiehser, Guy A, Jacobus, David. P, Diaz, Damaris S, Yang, Young-Sun, Milhous, Wilbur. K, Skillman, Donald. R

Volltext

Central nervous system exposure of next generation quinoline methanols is reduced relative to mefloquine after intravenous dosing in mice von Dow, Geoffrey S, Milner, Erin, Bathurst, Ian, Bhonsle, Jayendra, Caridha, Diana, Gardner, Sean, Gerena, Lucia, Kozar, Michael, Lanteri, Charlotte, Mannila, Anne, McCalmont, William, Moon, Jay, Read, Kevin D, Norval, Suzanne, Roncal, Norma, Shackleford, David M, Sousa, Jason, Steuten, Jessica, White, Karen L, Zeng, Qiang, Charman, Susan A

Volltext

The use of a prodrug approach to minimize potential CNS exposure of next generation quinoline methanols while maintaining efficacy in in vivo animal models von Sousa, Jason C., Milner, Erin, Carroll, Dustin, McCalmont, William, Gardner, Sean, Moon, Jay, Johnson, Jacob D., Lee, Patricia, Auschwitz, Jennifer, Roncal, Norma, Caridha, Diana, Tungteung, Anchalee, Zeng, Qiang, Reyes, Sean, Smith, Bryan, Li, Qigui, Kozar, Michael P., Melendez, Victor, Dow, Geoffrey

Volltext

Malaria Causal Prophylactic Activity of Imidazolidinedione Derivatives von Guan, Jian, Wang, Xihong, Smith, Kirsten, Ager, Arba, Gettayacamin, Montip, Kyle, Dennis E, Milhous, Wilbur K, Kozar, Michael P, Magill, Alan J, Lin, Ai J

Volltext

In vitro Biotransformation, in vivo Efficacy and Pharmacokinetics of Antimalarial Chalcones von Gutteridge, Clare E., Thota, Darshan S., Curtis, Sean M., Kozar, Michael P., Li, Qigui, Xie, Lisa, Zhang, Jing, Melendez, Victor, Asher, Constance O., Luong, Thulan T., Gerena, Lucia, Nichols, Daniel A., Montip, Gettayacamin

Volltext

Ketotifen is an antimalarial prodrug of norketotifen with blood schizonticidal and liver-stage efficacy von Milner, Erin, Sousa, Jason, Pybus, Brandon, Auschwitz, Jennifer, Caridha, Diana, Gardner, Sean, Grauer, Kristina, Harris, Erin, Hickman, Mark, Kozar, Michael P., Lee, Patricia, Leed, Susan, Li, Qigui, Melendez, Victor, Moon, Jay, Ngundam, Franklyn, O’Neil, Michael, Parriott, Sandi, Potter, Brittney, Sciotti, Rick, Tangteung, Anchalee, Dow, Geoffrey S.

Volltext

Pharmacokinetics, Safety, and Hydrolysis of Oral Pyrroloquinazolinediamines Administered in Single and Multiple Doses in Rats von QIGUI LI, KOZAR, Michael P, SKILLMAN, Donald R, SHEARER, Todd W, XIE, Lisa H, LIN, Ai J, SMITH, Kirsten S, YUANZHENG SI, ANOVA, Lalaine, JING ZHANG, MILHOUS, Wilbur K

Volltext