Endothelial Nitric-oxide Synthase (Type III) Is Activated and Becomes Calcium Independent upon Phosphorylation by Cyclic Nucleotide-dependent Protein Kinases von Butt, Elke, Bernhardt, Manfred, Smolenski, Albert, Kotsonis, Peter, Fröhlich, Lothar G., Sickmann, Albert, Meyer, Helmut E., Lohmann, Suzanne M., Schmidt, Harald H.H.W.

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The Soluble Guanylyl Cyclase Inhibitor 1H-[1,2,4]Oxadiazolo[4,3,-a]quinoxalin-1-one Is a Nonselective Heme Protein Inhibitor of Nitric Oxide Synthase and Other Cytochrome P-450 Enz... von Feelisch, M, Kotsonis, P, Siebe, J, Clement, B, Schmidt, H H

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Cloning and functional characterization of the guinea pig vanilloid receptor 1 von Savidge, Jonathan, Davis, Clare, Shah, Kirti, Colley, Sian, Phillips, Elsa, Ranasinghe, Sam, Winter, Janet, Kotsonis, Peter, Rang, Humphrey, McIntyre, Peter

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Tetrahydrobiopterin Inhibits Monomerization and Is Consumed during Catalysis in Neuronal NO Synthase von Reif, Andreas, Fröhlich, Lothar G., Kotsonis, Peter, Frey, Armin, Bömmel, Heike M., Schmidt, Harald H.H.W., Wink, David A., Pfleiderer, Wolfgang

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N-Formyl peptide receptor subtypes in human neutrophils activate L-plastin phosphorylation through different signal transduction intermediates von Paclet, Marie-Hélène, Davis, Clare, Kotsonis, Peter, Godovac-Zimmermann, Jasminka, Segal, Anthony W, Dekker, Lodewijk V

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Vanilloid Receptor TRPV1, Sensory C-Fibers, and Vascular Autoregulation: A Novel Mechanism Involved in Myogenic Constriction von Scotland, Ramona S, Chauhan, Sharmila, Davis, Clare, De Felipe, Carmen, Hunt, Stephen, Kabir, Jahangir, Kotsonis, Peter, Oh, Uhtaek, Ahluwalia, Amrita

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Autoinhibition of neuronal nitric oxide synthase: distinct effects of reactive nitrogen and oxygen species on enzyme activity von Kotsonis, P, Frey, A, Fröhlich, L G, Hofmann, H, Reif, A, Wink, D A, Feelisch, M, Schmidt, H H

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Anti-pterins as Tools to Characterize the Function of Tetrahydrobiopterin in NO Synthase von Bömmel, H M, Reif, A, Fröhlich, L G, Frey, A, Hofmann, H, Marecak, D M, Groehn, V, Kotsonis, P, La, M, Köster, S, Meinecke, M, Bernhardt, M, Weeger, M, Ghisla, S, Prestwich, G D, Pfleiderer, W, Schmidt, H H

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Biology and chemistry of the inhibition of nitric oxide synthases by pteridine-derivatives as therapeutic agents von Matter, Hans, Kotsonis, Peter

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Identification and Biological Characterization of 6-Aryl-7-isopropylquinazolinones as Novel TRPV1 Antagonists that Are Effective in Models of Chronic Pain von Culshaw, Andrew J, Bevan, Stuart, Christiansen, Martin, Copp, Prafula, Davis, Andrew, Davis, Clare, Dyson, Alex, Dziadulewicz, Edward K, Edwards, Lee, Eggelte, Hendrikus, Fox, Alyson, Gentry, Clive, Groarke, Alex, Hallett, Allan, Hart, Terance W, Hughes, Glyn A, Knights, Sally, Kotsonis, Peter, Lee, Wai, Lyothier, Isabelle, McBryde, Andrew, McIntyre, Peter, Paloumbis, George, Panesar, Moh, Patel, Sadhana, Seiler, Max-Peter, Yaqoob, Mohammed, Zimmermann, Kaspar

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Structural Basis for Pterin Antagonism in Nitric-oxide Synthase von Kotsonis, Peter, Fröhlich, Lothar G., Raman, C.S., Li, Huiying, Berg, Michael, Gerwig, Rainer, Groehn, Viola, Kang, Yonghan, Al-Masoudi, Najim, Taghavi-Moghadam, Shahriyar, Mohr, Detlev, Münch, Ursula, Schnabel, Joachim, Martásek, Pavel, Masters, Bettie S.S., Strobel, Hartmut, Poulos, Thomas, Matter, Hans, Pfleiderer, Wolfgang, Schmidt, Harald H. H.W.

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Autoinhibition of neuronal nitric oxide synthase: distinct effects of reactive nitrogen and oxygen species on enzyme activity von KOTSONIS, Peter, FREY, Armin, FRÖHLICH, Lothar G., HOFMANN, Heinrich, REIF, Andreas, WINK, David A., FEELISCH, Martin, SCHMIDT, Harald H. H. W.

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Structural Analysis of Isoform-Specific Inhibitors Targeting the Tetrahydrobiopterin Binding Site of Human Nitric Oxide Synthases von Matter, Hans, Kumar, H. S. Arun, Fedorov, Roman, Frey, Armin, Kotsonis, Peter, Hartmann, Elisabeth, Fröhlich, Lothar G, Reif, Andreas, Pfleiderer, Wolfgang, Scheurer, Peter, Ghosh, Dipak K, Schlichting, Ilme, Schmidt, Harald H. H. W

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Inhibition of Neuronal Nitric Oxide Synthase by 4-Amino Pteridine Derivatives:  Structure−Activity Relationship of Antagonists of (6R)-5,6,7,8-Tetrahydrobiopterin Cofactor von Fröhlich, Lothar G, Kotsonis, Peter, Traub, Hermann, Taghavi-Moghadam, Shahriyar, Al-Masoudi, Najim, Hofmann, Heinrich, Strobel, Hartmut, Matter, Hans, Pfleiderer, Wolfgang, Schmidt, Harald H. H. W

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Allosteric regulation of neuronal nitric oxide synthase by tetrahydrobiopterin and suppression of auto-damaging superoxide von Kotsonis, P, Fröhlich, L G, Shutenko, Z V, Horejsi, R, Pfleiderer, W, Schmidt, H H

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Structural Requirements for Inhibition of the Neuronal Nitric Oxide Synthase (NOS-I):  3D-QSAR Analysis of 4-Oxo- and 4-Amino-Pteridine-Based Inhibitors von Matter, Hans, Kotsonis, Peter, Klingler, Otmar, Strobel, Hartmut, Fröhlich, Lothar G, Frey, Armin, Pfleiderer, Wolfgang, Schmidt, Harald H. H. W

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Modulation of acetylcholine release from mouse cortex by protein kinase C von Iannazzo, Lydia, Kotsonis, Peter, Majewski, Henryk

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Structural basis for pterin antagonism in nitric-oxide synthase. Development of novel 4-oxo-pteridine antagonists of (6R)-5,6,7,8-tetrahydrobiopterin von Kotsonis, P, Fröhlich, L G, Raman, C S, Li, H, Berg, M, Gerwig, R, Groehn, V, Kang, Y, Al-Masoudi, N, Taghavi-Moghadam, S, Mohr, D, Münch, U, Schnabel, J, Martásek, P, Masters, B S, Strobel, H, Poulos, T, Matter, H, Pfleiderer, W, Schmidt, H H

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Modulation of acetylcholine release from mouse cortex by protein kinase C: Dependence on stimulation intensity von Iannazzo, Lydia, Kotsonis, Peter, Majewski, Henryk

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Identification and biological characterization of 6-aryl-7-isopropylquinazolinones as novel TRPV1 antagonists that are effective in models of chronicpain von CULSHAW, Andrew J, BEVAN, Stuart, FOX, Alyson, GENTRY, Clive, GROARKE, Alex, HALLETT, Allan, HART, Terance W, HUGHES, Glyn A, KNIGHTS, Sally, KOTSONIS, Peter, LEE, Wai, LYOTHIER, Isabelle, CHRISTIANSEN, Martin, MCBRYDE, Andrew, MCINTYRE, Peter, PALOUMBIS, George, PANESAR, Moh, PATEL, Sadhana, SEILER, Max-Peter, YAQOOB, Mohammed, ZIMMERMANN, Kaspar, COPP, Prafula, DAVIS, Andrew, DAVIS, Clare, DYSON, Alex, DZIADULEWICZ, Edward K, EDWARDS, Lee, EGGELTE, Hendrikus

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