Splicing factor SF3b as a target of the antitumor natural product pladienolide von Mizui, Yoshiharu, Kotake, Yoshihiko, Sagane, Koji, Owa, Takashi, Mimori-Kiyosue, Yuko, Shimizu, Hajime, Uesugi, Mai, Ishihama, Yasushi, Iwata, Masao

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Apratoxin A Shows Novel Pancreas-Targeting Activity through the Binding of Sec 61 von Huang, Kuan-Chun, Chen, Zhihong, Jiang, Yimin, Akare, Sandeep, Kolber-Simonds, Donna, Condon, Krista, Agoulnik, Sergei, Tendyke, Karen, Shen, Yongchun, Wu, Kuo-Ming, Mathieu, Steven, Choi, Hyeong-Wook, Zhu, Xiaojie, Shimizu, Hajime, Kotake, Yoshihiko, Gerwick, William H, Uenaka, Toshimitsu, Woodall-Jappe, Mary, Nomoto, Kenichi

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Total Synthesis of the Potent Antitumor Macrolides Pladienolide B and D von Kanada, Regina M., Itoh, Daisuke, Nagai, Mitsuo, Niijima, Jun, Asai, Naoki, Mizui, Yoshiharu, Abe, Shinya, Kotake, Yoshihiko

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Chemical Approaches to a Novel Antitumor Natural Product Pladienolide von Kotake, Yoshihiko

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Microregional antitumor activity of a small-molecule hypoxia-inducible factor 1 inhibitor von OKAMOTO, KIYOSHI, ITO, DAISUKE, MIYAZAKI, KAZUKI, WATANABE, SAORI, TOHYAMA, OSAMU, YOKOI, AKIRA, OZAWA, YOICHI, ASANO, MAKOTO, KAWAMURA, TAKANORI, YAMANE, YOSHINOBU, NAGAO, SATOSHI, FUNASAKA, SETSUO, KAMATA, JUNICHI, KOTAKE, YOSHIHIKO, AOKI, MIKA, TSUKAHARA, NAOKO, MIZUI, YOSHIHARU, TANAKA, ISAO, SAWADA, KOHEI

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Synthesis and Evaluation of Novel Pyrimido-Acridone, -Phenoxadine, and -Carbazole as Topoisomerase II Inhibitors von Kamata, Junichi, Okada, Toshimi, Kotake, Yoshihiko, Niijima, Jun, Nakamura, Katsuji, Uenaka, Toshimitsu, Yamaguchi, Atsumi, Tsukahara, Kappei, Nagasu, Takeshi, Koyanagi, Nozomu, Kitoh, Kyosuke, Yoshimatsu, Kentaro, Yoshino, Hiroshi, Sugumi, Hiroyuki

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A novel carbazole topoisomerase II poison, ER‐37328: potent tumoricidal activity against human solid tumors in vitro and in vivo von Nakamura, Katsuji, Uenaka, Toshimitsu, Nagasu, Takeshi, Sugumi, Hiroyuki, Yamaguchi, Atsumi, Kotake, Yoshihiko, Okada, Toshimi, Kamata, Junichi, Niijima, Jun, Taniguchi, Tomoyoshi, Koyanagi, Nozomu, Yoshino, Hiroshi, Kitoh, Kyosuke, Yoshimatsu, Kentaro

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Antitumor Activity of ER-37328, a Novel Carbazole Topoisomerase II Inhibitor von Nakamura, Katsuji, Sugumi, Hiroyuki, Yamaguchi, Atsumi, Uenaka, Toshimitsu, Kotake, Yoshihiko, Okada, Toshimi, Kamata, Junichi, Niijima, Jun, Nagasu, Takeshi, Koyanagi, Nozomu, Yoshino, Hiroshi, Kitoh, Kyosuke, Yoshimatsu, Kentaro

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Apratoxin‐A Induces Pancreatic Toxicity von Akare, Sandeep, Condon, Krista, Eckley, Sean, Huang, Kuan‐Chun, Chen, Zhihong, Jiang, Yimin, Kotake, Yoshihiko, Van Gessel, Yvonne, Hutto, David

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Selective degradation of splicing factor CAPER[alpha] by anticancer sulfonamides von Uehara, Taisuke, Minoshima, Yukinori, Sagane, Koji, Sugi, Naoko Hata, Mitsuhashi, Kaoru Ogawa, Yamamoto, Noboru, Kamiyama, Hiroshi, Takahashi, Kentaro, Kotake, Yoshihiko, Uesugi, Mai, Yokoi, Akira, Inoue, Atsushi, Yoshida, Taku, Mabuchi, Miyuki, Tanaka, Akito, Owa, Takashi

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Synthesis and structure–activity relationships of novel, potent, orally active hypoxia-inducible factor-1 inhibitors von Nagao, Satoshi, Yamane, Yoshinobu, Funasaka, Setsuo, Tanaka, Keigo, Miyazaki, Kazuki, Kotake, Yoshihiko, Kamata, Jun-ichi, Watanabe-Miyano, Saori, Toyama, Osamu, Ozawa, Yoichi, Mizui, Yoshiharu, Okamoto, Kiyoshi, Ito, Daisuke

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NOVEL SULFONAMIDES AS POTENTIAL, SYSTEMICALLY ACTIVE ANTITUMOR AGENTS von YOSHINO, H, UEDA, N, NIIJIMA, J, SUGUMI, H, KOTAKE, Y, KOYANAGI, N, YOSHIMATSU, K, ASADA, M, WATANABE, T, NAGASU, T, TSUKAHARA, K, IIJIMA, A, KITOH, K

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ChemInform Abstract: Chemical Approaches to a Novel Antitumor Natural Product Pladienolide von Kotake, Yoshihiko

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HERBOXIDIENE ANTIBODY-DRUG CONJUGATES AND METHODS OF USE von Fishkin, Nathan, Palacino, James, Samarakoon, Thiwanka, Okubo, Shinya, Miyano, Masayuki, Murai, Norio, Kotake, Yoshihiko, Arai, Kenzo

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Total Synthesis of the Potent Antitumor Macrolides Pladienolide B and D von Kanada, Regina M., Itoh, Daisuke, Nagai, Mitsuo, Niijima, Jun, Asai, Naoki, Mizui, Yoshiharu, Abe, Shinya, Kotake, Yoshihiko

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A SOLID STATE FORM OF PLADIENOLIDE PYRIDINE COMPOUNDS AND METHODS OF USE von CHAN, BETTY, KANADA SONABE, REGINA MIKIE, SMITH, PETER G, ENDO, ATSUSHI, GERARD, BAUDOUIN, KOTAKE, YOSHIHIKO, GEARHART, NICHOLAS C, KIRA, KAZUNOBU, THOMAS, MICHAEL P, WANG, JOHN, CHANDA, ARANI, ARAI, KENZO, PARK, EUNICE SUN, LIM, KIAN HUAT, LIU, XIANG, BUONAMICI, SILVIA, KEANEY, GREGG F, PAZOLLI, ERMIRA, MIYANO, MASAYUKI, TIVITMAHAISOON, PARCHAREE, ZHENG, GUO ZHU, YU, LIHUA, MURAI, NORIO, NAGAO, SATOSHI, PRAJAPATI, SUDEEP

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Innentitelbild: Total Synthesis of the Potent Antitumor Macrolides Pladienolide B and D (Angew. Chem. 23/2007) von Kanada, Regina M., Itoh, Daisuke, Nagai, Mitsuo, Niijima, Jun, Asai, Naoki, Mizui, Yoshiharu, Abe, Shinya, Kotake, Yoshihiko

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HERBOXIDIENE SPLICING MODULATOR ANTIBODY-DRUG CONJUGATES AND METHODS OF USE von SAMARAKOON, Thiwanka, FISHKIN, Nathan, OKUBO, Shinya, MIYANO, Masayuki, MURAI, Norio, PALACINO, James, ARAI, Kenzo, KOTAKE, Yoshihiko

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Certain pladienolide compounds and methods of use von Kira, Kazunobu, Palacino, James, Gerard, Baudouin, Endo, Atsushi, Ellery, Shelby, Hao, Ming-Hong, Nagao, Satoshi, Marcaurelle, Lisa A, Murai, Norio, Reynolds, Dominic, Keaney, Gregg F, Luo, Tuoping, Kotake, Yoshihiko, Arai, Kenzo, Liu, Xiang, Zheng, Guo Zhu, Lowe, Jason T, Nevalainen, Marta, Tivitmahaisoon, Parcharee, Wang, John, Prajapati, Sudeep, Gearhart, Nicholas C, Cook, Andrew, O'Shea, Morgan Welzel, Miyano, Masayuki, Kanada Sonobe, Regina Mikie

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HERBOXIDIENE ANTIBODY-DRUG CONJUGATES AND METHODS OF USE von OKUBO, SHINYA, MURAI, NORIO, FISHKIN, NATHAN, KOTAKE, YOSHIHIKO, MIYANO, MASAYUKI, SAMARAKOON, THIWANKA, PALACINO, JAMES, ARAI, KENZO

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