Th1 cytokines sensitize HER-expressing breast cancer cells to lapatinib von Showalter, Loral E, Oechsle, Crystal, Ghimirey, Nirmala, Steele, Chase, Czerniecki, Brian J, Koski, Gary K

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Murine Dendritic Cells Grown in Serum-Free Culture Show Potent Therapeutic Activity when Loaded with Novel Th Epitopes in an Orthotopic Model of HER2pos Breast Cancer von Showalter, Loral E., Czerniecki, Brian J., Kodumudi, Krithika, Koski, Gary K.

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Extracellular ATP and Toll-like receptor 2 agonists trigger in human monocytes an activation program that favors T helper 17 von Paustian, Christopher, Taylor, Patricia, Johnson, Terrence, Xu, Min, Ramirez, Nancy, Rosenthal, Kenneth S, Shu, Suyu, Cohen, Peter A, Czerniecki, Brian J, Koski, Gary K

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Sunitinib Combined with Th1 Cytokines Potentiates Apoptosis in Human Breast Cancer Cells and Suppresses Tumor Growth in a Murine Model of HER-2pos Breast Cancer von Ghimirey, Nirmala, Steele, Chase, Czerniecki, Brian J., Koski, Gary K., Showalter, Loral E.

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Reengineering dendritic cell-based anti-cancer vaccines von Koski, Gary K., Cohen, Peter A., Roses, Robert E., Xu, Shuwen, Czerniecki, Brian J.

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Paired Toll-like receptor agonists enhance vaccine therapy through induction of interleukin-12 von Zheng, Rongxiu, Cohen, Peter A, Paustian, Christopher A, Johnson, Terrence D, Lee, Walter T, Shu, Suyu, Koski, Gary K

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T-helper 1-type cytokines induce apoptosis and loss of HER-family oncodriver expression in murine and human breast cancer cells von Namjoshi, Prachi, Showalter, Lori, Czerniecki, Brian J, Koski, Gary K

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PIM kinase inhibitor AZD1208 in conjunction with Th1 cytokines potentiate death of breast cancer cellsin vitrowhile also maximizing suppression of tumor growthin vivo when combined... von Anwar, Ariel, Lepore, Carissa, Czerniecki, Brian J., Koski, Gary K., Showalter, Loral E.

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Th1 cytokines in conjunction with pharmacological Akt inhibition potentiate apoptosis of breast cancer cells in vitro and suppress tumor growth in vivo von Showalter, Loral, Czerniecki, Brian J., Koski, Gary K.

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Statin Drugs Plus Th1 Cytokines Potentiate Apoptosis and Ras Delocalization in Human Breast Cancer Lines and Combine with Dendritic Cell-Based Immunotherapy to Suppress Tumor Growt... von Oechsle, Crystal M., Showalter, Loral E., Novak, Colleen M., Czerniecki, Brain J., Koski, Gary K.

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Addition of anti-estrogen therapy to anti-HER2 dendritic cell vaccination improves regional nodal immune response and pathologic complete response rate in patients with ERpos/HER2p... von Lowenfeld, Lea, Zaheer, Salman, Oechsle, Crystal, Fracol, Megan, Datta, Jashodeep, Xu, Shuwen, Fitzpatrick, Elizabeth, Roses, Robert E., Fisher, Carla S., McDonald, Elizabeth S., Zhang, Paul J., DeMichele, Angela, Mick, Rosemarie, Koski, Gary K., Czerniecki, Brian J.

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Abstract 3993: Th1 cytokines regulate apoptotic cell death and HER family RTK expression in murine and human breast cancer lines von Namjoshi, Prachi M., Showalter, Lori, Czerniecki, Brian, Koski, Gary K.

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A Novel Dendritic Cell-based Immunization Approach for the Induction of Durable Th1-polarized Anti-HER-2/neu Responses in Women With Early Breast Cancer von KOSKI, Gary K, KOLDOVSKY, Ursula, ZHANG, Paul, CZERNIECKI, Brian J, SHUWEN XU, MICK, Rosemarie, SHARMA, Anupama, FITZPATRICK, Elizabeth, WEINSTEIN, Susan, NISENBAUM, Harvey, LEVINE, Bruce L, FOX, Kevin

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Toll-like receptor agonists as third signals for dendritic cell-tumor fusion vaccines von Cho, Edward I., Tan, Chunrui, Koski, Gary K., Cohen, Peter A., Shu, Suyu, Lee, Walter T.

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Calcium mobilizing treatment acts as a co-signal for TLR-mediated induction of Interleukin-12 (IL-12p70) secretion by murine bone marrow-derived dendritic cells von Huang, Emily, Showalter, Loral, Xu, Shuwen, Czernliecki, Brian J., Koski, Gary K.

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Targeting HER-2/neu in early breast cancer development using dendritic cells with staged interleukin-12 burst secretion von Czerniecki, Brian J, Koski, Gary K, Koldovsky, Ursula, Xu, Shuwen, Cohen, Peter A, Mick, Rosemarie, Nisenbaum, Harvey, Pasha, Terry, Xu, Min, Fox, Kevin R, Weinstein, Susan, Orel, Susan G, Vonderheide, Robert, Coukos, George, DeMichele, Angela, Araujo, Louis, Spitz, Francis R, Rosen, Mark, Levine, Bruce L, June, Carl, Zhang, Paul J

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Progressive loss of anti-HER2 CD4+ T-helper type 1 response in breast tumorigenesis and the potential for immune restoration von Datta, Jashodeep, Rosemblit, Cinthia, Berk, Erik, Showalter, Lori, Namjoshi, Prachi, Mick, Rosemarie, Lee, Kathreen P, Brod, Andrew M, Yang, Rachel L, Kelz, Rachel R, Fitzpatrick, Elizabeth, Hoyt, Clifford, Feldman, Michael D, Zhang, Paul J, Xu, Shuwen, Koski, Gary K, Czerniecki, Brian J

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Identification of Immunogenic MHC Class II Human HER3 Peptides that Mediate Anti-HER3 CD4 + Th1 Responses and Potential Use as a Cancer Vaccine von Basu, Amrita, Albert, Gabriella K, Awshah, Sabrina, Datta, Jashodeep, Kodumudi, Krithika N, Gallen, Corey, Beyer, Amber, Smalley, Keiran S M, Rodriguez, Paulo C, Duckett, Derek R, Forsyth, Peter A, Soyano, Aixa, Koski, Gary K, Lima Barros Costa, Ricardo, Han, Heather, Soliman, Hatem, Lee, Marie Catherine, Kalinski, Pawel, Czerniecki, Brian J

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Sunitinib Combined with Th1 Cytokines Potentiates Apoptosis in Human Breast Cancer Cells and Suppresses Tumor Growth in a Murine Model of HER-2[sup.pos] Breast Cancer von Ghimirey, Nirmala, Steele, Chase, Czerniecki, Brian J, Koski, Gary K, Showalter, Loral E

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Adenovirus type 5 vectors induce dendritic cell differentiation in human CD14+ monocytes cultured under serum-free conditions von Lyakh, Lyudmila A., Koski, Gary K., Young, Howard A., Spence, Sally E., Cohen, Peter A., Rice, Nancy R.

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