Synergy between Variant PRC1 Complexes Defines Polycomb-Mediated Gene Repression von Fursova, Nadezda A., Blackledge, Neil P., Nakayama, Manabu, Ito, Shinsuke, Koseki, Yoko, Farcas, Anca M., King, Hamish W., Koseki, Haruhiko, Klose, Robert J.

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PCGF3/5–PRC1 initiates Polycomb recruitment in X chromosome inactivation von Almeida, Mafalda, Pintacuda, Greta, Masui, Osamu, Koseki, Yoko, Gdula, Michal, Cerase, Andrea, Brown, David, Mould, Arne, Innocent, Cassandravictoria, Nakayama, Manabu, Schermelleh, Lothar, Nesterova, Tatyana B., Koseki, Haruhiko, Brockdorff, Neil

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Variant PCGF1-PRC1 links PRC2 recruitment with differentiation-associated transcriptional inactivation at target genes von Sugishita, Hiroki, Kondo, Takashi, Ito, Shinsuke, Nakayama, Manabu, Yakushiji-Kaminatsui, Nayuta, Kawakami, Eiryo, Koseki, Yoko, Ohinata, Yasuhide, Sharif, Jafar, Harachi, Mio, Blackledge, Neil P., Klose, Robert J., Koseki, Haruhiko

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A Family of Vertebrate-Specific Polycombs Encoded by the LCOR/LCORL Genes Balance PRC2 Subtype Activities von Conway, Eric, Jerman, Emilia, Healy, Evan, Ito, Shinsuke, Holoch, Daniel, Oliviero, Giorgio, Deevy, Orla, Glancy, Eleanor, Fitzpatrick, Darren J., Mucha, Marlena, Watson, Ariane, Rice, Alan M., Chammas, Paul, Huang, Christine, Pratt-Kelly, Indigo, Koseki, Yoko, Nakayama, Manabu, Ishikura, Tomoyuki, Streubel, Gundula, Wynne, Kieran, Hokamp, Karsten, McLysaght, Aoife, Ciferri, Claudio, Di Croce, Luciano, Cagney, Gerard, Margueron, Raphaël, Koseki, Haruhiko, Bracken, Adrian P.

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FBXL19 recruits CDK-Mediator to CpG islands of developmental genes priming them for activation during lineage commitment von Dimitrova, Emilia, Kondo, Takashi, Feldmann, Angelika, Nakayama, Manabu, Koseki, Yoko, Konietzny, Rebecca, Kessler, Benedikt M, Koseki, Haruhiko, Klose, Robert J

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Maintenance DNA methylation in pre-meiotic germ cells regulates meiotic prophase by facilitating homologous chromosome pairing von Takada, Yuki, Yaman-Deveci, Ruken, Shirakawa, Takayuki, Sharif, Jafar, Tomizawa, Shin-Ichi, Miura, Fumihito, Ito, Takashi, Ono, Michio, Nakajima, Kuniko, Koseki, Yoko, Shiotani, Fuyuko, Ishiguro, Kei-Ichiro, Ohbo, Kazuyuki, Koseki, Haruhiko

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PCGF1-PRC1 links chromatin repression with DNA replication during hematopoietic cell lineage commitment von Takano, Junichiro, Ito, Shinsuke, Dong, Yixing, Sharif, Jafar, Nakajima-Takagi, Yaeko, Umeyama, Taichi, Han, Yong-Woon, Isono, Kyoichi, Kondo, Takashi, Iizuka, Yusuke, Miyai, Tomohiro, Koseki, Yoko, Ikegaya, Mika, Sakihara, Mizuki, Nakayama, Manabu, Ohara, Osamu, Hasegawa, Yoshinori, Hashimoto, Kosuke, Arner, Erik, Klose, Robert J., Iwama, Atsushi, Koseki, Haruhiko, Ikawa, Tomokatsu

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Ash1l methylates Lys36 of histone H3 independently of transcriptional elongation to counteract polycomb silencing von Miyazaki, Hitomi, Higashimoto, Ken, Yada, Yukari, Endo, Takaho A, Sharif, Jafar, Komori, Toshiharu, Matsuda, Masashi, Koseki, Yoko, Nakayama, Manabu, Soejima, Hidenobu, Handa, Hiroshi, Koseki, Haruhiko, Hirose, Susumu, Nishioka, Kenichi

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Requirement of Stat3 Signaling in the Postnatal Development of Thymic Medullary Epithelial Cells von Satoh, Rumi, Kakugawa, Kiyokazu, Yasuda, Takuwa, Yoshida, Hisahiro, Sibilia, Maria, Katsura, Yoshimoto, Levi, Ben, Abramson, Jakub, Koseki, Yoko, Koseki, Haruhiko, van Ewijk, Willem, Hollander, Georg A, Kawamoto, Hiroshi

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Activation of Endogenous Retroviruses in Dnmt1−/− ESCs Involves Disruption of SETDB1-Mediated Repression by NP95 Binding to Hemimethylated DNA von Sharif, Jafar, Endo, Takaho A., Nakayama, Manabu, Karimi, Mohammad M., Shimada, Midori, Katsuyama, Kayoko, Goyal, Preeti, Brind’Amour, Julie, Sun, Ming-An, Sun, Zhixiong, Ishikura, Tomoyuki, Mizutani-Koseki, Yoko, Ohara, Osamu, Shinkai, Yoichi, Nakanishi, Makoto, Xie, Hehuang, Lorincz, Matthew C., Koseki, Haruhiko

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Human NK cell development in hIL-7 and hIL-15 knockin NOD/SCID/IL2rgKO mice von Matsuda, Masashi, Ono, Rintaro, Iyoda, Tomonori, Endo, Takaho, Iwasaki, Makoto, Tomizawa-Murasawa, Mariko, Saito, Yoriko, Kaneko, Akiko, Shimizu, Kanako, Yamada, Daisuke, Ogonuki, Narumi, Watanabe, Takashi, Nakayama, Manabu, Koseki, Yoko, Kezuka-Shiotani, Fuyuko, Hasegawa, Takanori, Yabe, Hiromasa, Kato, Shunichi, Ogura, Atsuo, Shultz, Leonard D, Ohara, Osamu, Taniguchi, Masaru, Koseki, Haruhiko, Fujii, Shin-Ichiro, Ishikawa, Fumihiko

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Polycomb repressive complexes 1 and 2 are each essential for maintenance of X inactivation in extra-embryonic lineages von Masui, Osamu, Corbel, Catherine, Nagao, Koji, Endo, Takaho A., Kezuka, Fuyuko, Diabangouaya, Patricia, Nakayama, Manabu, Kumon, Mami, Koseki, Yoko, Obuse, Chikashi, Koseki, Haruhiko, Heard, Edith

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RING1 contributes to early proximal-distal specification of the forelimb bud by restricting Meis2 expression von Yakushiji-Kaminatsui, Nayuta, Kondo, Takashi, Endo, Takaho A., Koseki, Yoko, Kondo, Kaori, Ohara, Osamu, Vidal, Miguel, Koseki, Haruhiko

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Mammalian Polycomb-Like Pcl2/Mtf2 Is a Novel Regulatory Component of PRC2 That Can Differentially Modulate Polycomb Activity both at the Hox Gene Cluster and at Cdkn2a Genes von Li, Xiangzhi, Isono, Kyo-ichi, Yamada, Daisuke, Endo, Takaho A., Endoh, Mitsuhiro, Shinga, Jun, Mizutani-Koseki, Yoko, Otte, Arie P., Casanova, Miguel, Kitamura, Hiroshi, Kamijo, Takehiko, Sharif, Jafar, Ohara, Osamu, Toyada, Tetsuro, Bernstein, Bradley E., Brockdorff, Neil, Koseki, Haruhiko

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Mammalian Polyhomeotic Homologues Phc2 and Phc1 Act in Synergy To Mediate Polycomb Repression of Hox Genes von Isono, Kyo-ichi, Fujimura, Yu-ichi, Shinga, Jun, Yamaki, Makoto, O-Wang, Jiyang, Takihara, Yoshihiro, Murahashi, Yasuaki, Takada, Yuki, Mizutani-Koseki, Yoko, Koseki, Haruhiko

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Mammalian polycomb-mediated repression of Hox genes requires the essential spliceosomal protein Sf3b1 von Isono, Kyoichi, Mizutani-Koseki, Yoko, Komori, Toshihisa, Schmidt-Zachmann, Marion S, Koseki, Haruhiko

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Regulation of Th2 Cell Differentiation by mel-18, a Mammalian Polycomb Group Gene von Kimura, Motoko, Koseki, Yoko, Yamashita, Masakatsu, Watanabe, Naohiro, Shimizu, Chiori, Katsumoto, Takuo, Kitamura, Toshio, Taniguchi, Masaru, Koseki, Haruhiko, Nakayama, Toshinori

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Establishment of mouse stem cells that can recapitulate the developmental potential of primitive endoderm von Ohinata, Yasuhide, Endo, Takaho A, Sugishita, Hiroki, Watanabe, Takashi, Iizuka, Yusuke, Kawamoto, Yurie, Saraya, Atsunori, Kumon, Mami, Koseki, Yoko, Kondo, Takashi, Ohara, Osamu, Koseki, Haruhiko

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Variant PRC1 complex-dependent H2A ubiquitylation drives PRC2 recruitment and polycomb domain formation von Blackledge, Neil P, Farcas, Anca M, Kondo, Takashi, King, Hamish W, McGouran, Joanna F, Hanssen, Lars L P, Ito, Shinsuke, Cooper, Sarah, Kondo, Kaori, Koseki, Yoko, Ishikura, Tomoyuki, Long, Hannah K, Sheahan, Thomas W, Brockdorff, Neil, Kessler, Benedikt M, Koseki, Haruhiko, Klose, Robert J

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KDM2 proteins constrain transcription from CpG island gene promoters independently of their histone demethylase activity von Turberfield, Anne H, Kondo, Takashi, Nakayama, Manabu, Koseki, Yoko, King, Hamish W, Koseki, Haruhiko, Klose, Robert J

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