Tuberculosis and lung damage: from epidemiology to pathophysiology von Ravimohan, Shruthi, Kornfeld, Hardy, Weissman, Drew, Bisson, Gregory P

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Mycobacterium tuberculosis induces an atypical cell death mode to escape from infected macrophages von Lee, Jinhee, Repasy, Teresa, Papavinasasundaram, Kadamba, Sassetti, Christopher, Kornfeld, Hardy

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Persistent inflammation during anti-tuberculosis treatment with diabetes comorbidity von Kumar, Nathella Pavan, Fukutani, Kiyoshi F, Shruthi, Basavaradhya S, Alves, Thabata, Silveira-Mattos, Paulo S, Rocha, Michael S, West, Kim, Natarajan, Mohan, Viswanathan, Vijay, Babu, Subash, Andrade, Bruno B, Kornfeld, Hardy

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Metformin enhances anti-mycobacterial responses by educating CD8+ T-cell immunometabolic circuits von Böhme, Julia, Martinez, Nuria, Li, Shamin, Lee, Andrea, Marzuki, Mardiana, Tizazu, Anteneh Mehari, Ackart, David, Frenkel, Jessica Haugen, Todd, Alexandra, Lachmandas, Ekta, Lum, Josephine, Shihui, Foo, Ng, Tze Pin, Lee, Bernett, Larbi, Anis, Netea, Mihai G., Basaraba, Randall, van Crevel, Reinout, Newell, Evan, Kornfeld, Hardy, Singhal, Amit

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Glycerol contributes to tuberculosis susceptibility in male mice with type 2 diabetes von Martinez, Nuria, Smulan, Lorissa J., Jameson, Michael L., Smith, Clare M., Cavallo, Kelly, Bellerose, Michelle, Williams, John, West, Kim, Sassetti, Christopher M., Singhal, Amit, Kornfeld, Hardy

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Systems Immunology of Diabetes-Tuberculosis Comorbidity Reveals Signatures of Disease Complications von Prada-Medina, Cesar A., Fukutani, Kiyoshi F., Pavan Kumar, Nathella, Gil-Santana, Leonardo, Babu, Subash, Lichtenstein, Flávio, West, Kim, Sivakumar, Shanmugam, Menon, Pradeep A., Viswanathan, Vijay, Andrade, Bruno B., Nakaya, Helder I., Kornfeld, Hardy

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Macrophage apoptosis in tuberculosis von Lee, Jinhee, Hartman, Michelle, Kornfeld, Hardy

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Diabetes and immunity to tuberculosis von Martinez, Nuria, Kornfeld, Hardy

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Mycobacterium tuberculosis blocks crosslinking of annexin-1 and apoptotic envelope formation on infected macrophages to maintain virulence von Remold, Heinz G, Gan, Huixian, Lee, Jinhee, Ren, Fucheng, Chen, Minjian, Kornfeld, Hardy

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Sirtuin 3 Downregulation in Mycobacterium tuberculosis -Infected Macrophages Reprograms Mitochondrial Metabolism and Promotes Cell Death von Smulan, Lorissa J, Martinez, Nuria, Kiritsy, Michael C, Kativhu, Chido, Cavallo, Kelly, Sassetti, Christopher M, Singhal, Amit, Remold, Heinz G, Kornfeld, Hardy

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Chitinase and indoleamine 2, 3-dioxygenase are prognostic biomarkers for unfavorable treatment outcomes in pulmonary tuberculosis von Kumar, Nathella Pavan, Nancy, Arul, Viswanathan, Vijay, Sivakumar, Shanmugam, Thiruvengadam, Kannan, Ahamed, Shaik Fayaz, Hissar, Syed, Kornfeld, Hardy, Babu, Subash

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Tuberculosis Susceptibility and Vaccine Protection Are Independently Controlled by Host Genotype von Smith, Clare M, Proulx, Megan K, Olive, Andrew J, Laddy, Dominick, Mishra, Bibhuti B, Moss, Caitlin, Gutierrez, Nuria Martinez, Bellerose, Michelle M, Barreira-Silva, Palmira, Phuah, Jia Yao, Baker, Richard E, Behar, Samuel M, Kornfeld, Hardy, Evans, Thomas G, Beamer, Gillian, Sassetti, Christopher M

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Intracellular bacillary burden reflects a burst size for Mycobacterium tuberculosis in vivo von Repasy, Teresa, Lee, Jinhee, Marino, Simeone, Martinez, Nuria, Kirschner, Denise E, Hendricks, Gregory, Baker, Stephen, Wilson, Andrew A, Kotton, Darrell N, Kornfeld, Hardy

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Cytokine and chemokine profiles in pulmonary tuberculosis with pre-diabetes von Rajamanickam, Anuradha, Kothandaraman, Sanaadhan P, Kumar, Nathella Pavan, Viswanathan, Vijay, Shanmugam, Sivakumar, Hissar, Syed, Nott, Sujatha, Kornfeld, Hardy, Babu, Subash

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Distinct TB-antigen stimulated cytokine profiles as predictive biomarkers for unfavorable treatment outcomes in pulmonary tuberculosis von Pandiarajan, Arul Nancy, Kumar, Nathella Pavan, Selvaraj, Nandhini, Ahamed, Shaik Fayaz, Viswanathan, Vijay, Thiruvengadam, Kannan, Hissar, Syed, Shanmugam, Sivakumar, Bethunaickan, Ramalingam, Nott, Sujatha, Kornfeld, Hardy, Babu, Subash

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Diabetes Is Associated with Worse Clinical Presentation in Tuberculosis Patients from Brazil: A Retrospective Cohort Study von Gil-Santana, Leonardo, Almeida-Junior, Jilson L, Oliveira, Carolina A M, Hickson, Lucas S, Daltro, Carla, Castro, Simone, Kornfeld, Hardy, Netto, Eduardo M, Andrade, Bruno B

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Defects in early cell recruitment contribute to the increased susceptibility to respiratory Klebsiella pneumoniae infection in diabetic mice von Martinez, Nuria, Ketheesan, Natkunam, Martens, Gregory W., West, Kim, Lien, Egil, Kornfeld, Hardy

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Elevated levels of matrix metalloproteinases reflect severity and extent of disease in tuberculosis-diabetes co-morbidity and are predominantly reversed following standard anti-tub... von Kumar, Nathella P, Moideen, Kadar, Viswanathan, Vijay, Shruthi, Basavaradhya S, Sivakumar, Shanmugam, Menon, Pradeep A, Kornfeld, Hardy, Babu, Subash

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Acute Phase Proteins Are Baseline Predictors of Tuberculosis Treatment Failure von Kumar, Nathella Pavan, Moideen, Kadar, Nancy, Arul, Viswanathan, Vijay, Thiruvengadam, Kannan, Sivakumar, Shanmugam, Hissar, Syed, Kornfeld, Hardy, Babu, Subash

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Macrophage Apoptosis in Response to High Intracellular Burden of Mycobacterium tuberculosis Is Mediated by a Novel Caspase-Independent Pathway von Lee, Jinhee, Remold, Heinz G, Ieong, Michael H, Kornfeld, Hardy

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