Development of subtype-selective oestrogen receptor-based therapeutics von Nilsson, Stefan, Koehler, Konrad F., Gustafsson, Jan-Åke

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Reflections on the Discovery and Significance of Estrogen Receptor β von Koehler, Konrad F, Helguero, Luisa A, Haldosén, Lars-Arne, Warner, Margaret, Gustafsson, Jan-Åke

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A designed P1 cysteine mimetic for covalent and non-covalent inhibitors of HCV NS3 protease von Narjes, Frank, Koehler, Konrad F, Koch, Uwe, Gerlach, Benjamin, Colarusso, Stefania, Steinkühler, Christian, Brunetti, Mirko, Altamura, Sergio, De Francesco, Raffaele, Matassa, Victor G

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Oestrogen Receptors and Selective Oestrogen Receptor Modulators: Molecular and Cellular Pharmacology von Nilsson, Stefan, Koehler, Konrad F.

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Thyroid Receptor Ligands. 1. Agonist Ligands Selective for the Thyroid Receptor β1 von Ye, Liu, Li, Yi-Lin, Mellström, Karin, Mellin, Charlotta, Bladh, Lars-Göran, Koehler, Konrad, Garg, Neeraj, Garcia Collazo, Ana Maria, Litten, Chris, Husman, Bolette, Persson, Karina, Ljunggren, Jan, Grover, Gary, Sleph, Paul G, George, Rocco, Malm, Johan

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Virtual Screening for Aryl Hydrocarbon Receptor Binding Prediction von Lo Piparo, Elena, Koehler, Konrad, Chana, Antonio, Benfenati, Emilio

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Liver-Selective Glucocorticoid Antagonists:  A Novel Treatment for Type 2 Diabetes von von Geldern, Thomas W, Tu, Noah, Kym, Philip R, Link, James T, Jae, Hwan-Soo, Lai, Chunqiu, Apelqvist, Theresa, Rhonnstad, Patrik, Hagberg, Lars, Koehler, Konrad, Grynfarb, Marlena, Goos-Nilsson, Annika, Sandberg, Johnny, Österlund, Marie, Barkhem, Tomas, Höglund, Marie, Wang, Jiahong, Fung, Steven, Wilcox, Denise, Nguyen, Phong, Jakob, Clarissa, Hutchins, Charles, Färnegårdh, Mathias, Kauppi, Björn, Öhman, Lars, Jacobson, Peer B

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Glucocorticoid Receptor Point Mutation V571M Facilitates Coactivator and Ligand Binding by Structural Rearrangement and Stabilization von Carlsson, Peter, Koehler, Konrad F, Nilsson, Lennart

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Mouse Estrogen Receptor β Isoforms Exhibit Differences in Ligand Selectivity and Coactivator Recruitment von Zhao, Chunyan, Toresson, Gudrun, Xu, Li, Koehler, Konrad F, Gustafsson, Jan-Åke, Dahlman-Wright, Karin

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Thyroid Receptor Ligands. 3. Design and Synthesis of 3,5-Dihalo-4-alkoxyphenylalkanoic Acids as Indirect Antagonists of the Thyroid Hormone Receptor von Hedfors, Åsa, Appelqvist, Theresa, Carlsson, Bo, Bladh, Lars-Göran, Litten, Chris, Agback, Peter, Grynfarb, Marlena, Koehler, Konrad F, Malm, Johan

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Thyroid receptor ligands. Part 4: 4′-amido bioisosteric ligands selective for the thyroid hormone receptor beta von Li, Yi-Lin, Litten, Chris, Koehler, Konrad F., Mellström, Karin, Garg, Neeraj, Garcia Collazo, Ana Maria, Färnegård, Mathias, Grynfarb, Marlena, Husman, Bolette, Sandberg, Johnny, Malm, Johan

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Thyroid receptor ligands. Part 5: Novel bicyclic agonist ligands selective for the thyroid hormone receptor β von Garcia Collazo, Ana-Maria, Koehler, Konrad F., Garg, Neeraj, Färnegårdh, Mathias, Husman, Bolette, Ye, Liu, Ljunggren, Jan, Mellström, Karin, Sandberg, Johnny, Grynfarb, Marlena, Ahola, Harri, Malm, Johan

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Abstract 3843: LSD1 modulation by allosteric ligands von Emond, Wei B., Geitmann, Matthis, Jarvius, Malin, Koehler, Konrad, Källblad, Per, Niklasson, Mia, Parrow, Vendela, Sawant, Rajiv, Sjöberg, Maria, Winquist, Johan, Segerman, Anna, Bremberg, Ulf

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Discovery of 3-Cyano- N-(3-(1-isobutyrylpiperidin-4-yl)-1-methyl-4-(trifluoromethyl)-1 H-pyrrolo[2,3- b]pyridin-5-yl)benzamide: A Potent, Selective, and Orally Bioavailable Retinoi... von Schnute, Mark E, Wennerstål, Mattias, Alley, Jennifer, Bengtsson, Martin, Blinn, James R, Bolten, Charles W, Braden, Timothy, Bonn, Tomas, Carlsson, Bo, Caspers, Nicole, Chen, Ming, Choi, Chulho, Collis, Leon P, Crouse, Kimberly, Färnegårdh, Mathias, Fennell, Kimberly F, Fish, Susan, Flick, Andrew C, Goos-Nilsson, Annika, Gullberg, Hjalmar, Harris, Peter K, Heasley, Steven E, Hegen, Martin, Hromockyj, Alexander E, Hu, Xiao, Husman, Bolette, Janosik, Tomasz, Jones, Peter, Kaila, Neelu, Kallin, Elisabet, Kauppi, Björn, Kiefer, James R, Knafels, John, Koehler, Konrad, Kruger, Lars, Kurumbail, Ravi G, Kyne, Jr, Robert E, Li, Wei, Löfstedt, Joakim, Long, Scott A, Menard, Carol A, Mente, Scot, Messing, Dean, Meyers, Marvin J, Napierata, Lee, Nöteberg, Daniel, Nuhant, Philippe, Pelc, Matthew J, Prinsen, Michael J, Rhönnstad, Patrik, Backström-Rydin, Eva, Sandberg, Johnny, Sandström, Maria, Shah, Falgun, Sjöberg, Maria, Sundell, Aron, Taylor, Alexandria P, Thorarensen, Atli, Trujillo, John I, Trzupek, John D, Unwalla, Ray, Vajdos, Felix F, Weinberg, Robin A, Wood, David C, Xing, Li, Zamaratski, Edouard, Zapf, Christoph W, Zhao, Yajuan, Wilhelmsson, Anna, Berstein, Gabriel

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Synthesis of benzo-fused benzodiazepines employed as probes of the agonist pharmacophore of benzodiazepine receptors von Zhang, Weijiang, Koehler, Konrad F, Harris, Bradford, Skolnick, Phil, Cook, James M

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Abstract 705: Potentiation of immunotherapy by LSD1 modulation von Emond, Wei B., Sawant, Rajiv, Geitmann, Matthis, Winquist, Johan, Brandt, Peter, Bremberg, Ulf, Källblad, Per, Parrow, Vendela, Andersson, Claes, Blom, Kristin, Najafi, Nasrin, Bergström, Tobias, Swartling, Fredrik J., Hellström, Mats, Koehler, Konrad F.

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Discovery of 3‑Cyano‑N‑(3-(1-isobutyrylpiperidin-4-yl)-1-methyl-4-(trifluoromethyl)‑1H‑pyrrolo[2,3‑b]pyridin-5-yl)benzamide: A Potent, Selective, and Orally Bioavailable Retinoic A... von Schnute, Mark E, Wennerstål, Mattias, Alley, Jennifer, Bengtsson, Martin, Blinn, James R, Bolten, Charles W, Braden, Timothy, Bonn, Tomas, Carlsson, Bo, Caspers, Nicole, Chen, Ming, Choi, Chulho, Collis, Leon P, Crouse, Kimberly, Färnegårdh, Mathias, Fennell, Kimberly F, Fish, Susan, Flick, Andrew C, Goos-Nilsson, Annika, Gullberg, Hjalmar, Harris, Peter K, Heasley, Steven E, Hegen, Martin, Hromockyj, Alexander E, Hu, Xiao, Husman, Bolette, Janosik, Tomasz, Jones, Peter, Kaila, Neelu, Kallin, Elisabet, Kauppi, Björn, Kiefer, James R, Knafels, John, Koehler, Konrad, Kruger, Lars, Kurumbail, Ravi G, Kyne, Robert E, Li, Wei, Löfstedt, Joakim, Long, Scott A, Menard, Carol A, Mente, Scot, Messing, Dean, Meyers, Marvin J, Napierata, Lee, Nöteberg, Daniel, Nuhant, Philippe, Pelc, Matthew J, Prinsen, Michael J, Rhönnstad, Patrik, Backström-Rydin, Eva, Sandberg, Johnny, Sandström, Maria, Shah, Falgun, Sjöberg, Maria, Sundell, Aron, Taylor, Alexandria P, Thorarensen, Atli, Trujillo, John I, Trzupek, John D, Unwalla, Ray, Vajdos, Felix F, Weinberg, Robin A, Wood, David C, Xing, Li, Zamaratski, Edouard, Zapf, Christoph W, Zhao, Yajuan, Wilhelmsson, Anna, Berstein, Gabriel

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Synthetic and computer-assisted analyses of the pharmacophore for the benzodiazepine receptor inverse agonist site von Allen, Michael S, Tan, Yun C, Trudell, Mark L, Narayanan, Kris, Schindler, Liesl R, Martin, Michael J, Schultz, Christopher, Hagen, Timothy J, Koehler, Konrad F

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Synthetic and computer-assisted analysis of the structural requirements for selective, high-affinity ligand binding to diazepam-insensitive benzodiazepine receptors von Wong, Garry, Koehler, Konrad F, Skolnick, Phil, Gu, Zi Qiang, Ananthan, Subramaniam, Schonholzer, Peter, Hunkeler, Walter, Zhang, Weijiang, Cook, James M

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Predictive binding of .beta.-carboline inverse agonists and antagonists via the CoMFA/GOLPE approach von Allen, Michael S, LaLoggia, Anthony J, Dorn, Linda J, Martin, Michael J, Costantino, Gabriele, Hagen, Timothy J, Koehler, Konrad F, Skolnick, Phil, Cook, James M

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