Application of Cancer Organoid Model for Drug Screening and Personalized Therapy von Kondo, Jumpei, Inoue, Masahiro

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Retaining cell-cell contact enables preparation and culture of spheroids composed of pure primary cancer cells from colorectal cancer von Kondo, Jumpei, Endo, Hiroko, Okuyama, Hiroaki, Ishikawa, Osamu, Iishi, Hiroyasu, Tsujii, Masahiko, Ohue, Masayuki, Inoue, Masahiro

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ASURAT: functional annotation-driven unsupervised clustering of single-cell transcriptomes von Iida, Keita, Kondo, Jumpei, Wibisana, Johannes Nicolaus, Inoue, Masahiro, Okada, Mariko

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High‐throughput screening in colorectal cancer tissue‐originated spheroids von Kondo, Jumpei, Ekawa, Tomoya, Endo, Hiroko, Yamazaki, Kanami, Tanaka, Norio, Kukita, Yoji, Okuyama, Hiroaki, Okami, Jiro, Imamura, Fumio, Ohue, Masayuki, Kato, Kikuya, Nomura, Taisei, Kohara, Arihiro, Mori, Seiichi, Dan, Shingo, Inoue, Masahiro

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Small subset of Wnt‐activated cells is an initiator of regrowth in colorectal cancer organoids after irradiation von Endo, Hiroko, Kondo, Jumpei, Onuma, Kunishige, Ohue, Masayuki, Inoue, Masahiro

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Constitutive Activation of the Tumor Suppressor p53 in Hepatocytes Paradoxically Promotes Non-Cell Autonomous Liver Carcinogenesis von Makino, Yuki, Hikita, Hayato, Fukumoto, Kenji, Sung, Ji Hyun, Sakano, Yoshihiro, Murai, Kazuhiro, Sakane, Sadatsugu, Kodama, Takahiro, Sakamori, Ryotaro, Kondo, Jumpei, Kobayashi, Shogo, Tatsumi, Tomohide, Takehara, Tetsuo

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Establishment of a novel 70K Mac-2 binding protein antibody through screening of fucosylation-related antibodies von Masuda, Mika, Asuka, Tatsuya, Terao, Naoko, Nishino, Shinsuke, Ikeda, Shun, Takamatsu, Shinji, Kondo, Jumpei, Miyoshi, Eiji

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Ex vivo chemosensitivity assay using primary ovarian cancer organoids for predicting clinical response and screening effective drugs von Ito, Yu, Kondo, Jumpei, Masuda, Masamune, Matsuzaki, Shinya, Onuma, Kunishige, Kanda, Mizuki, Watanabe, Yuko, Sakaguchi, Hitomi, Yoshino, Kiyoshi, Ueda, Yutaka, Kamiura, Shoji, Kimura, Tadashi, Inoue, Masahiro

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Liver ductal organoids reconstruct intrahepatic biliary trees in decellularized liver grafts von Tomofuji, Katsuhiro, Fukumitsu, Ken, Kondo, Jumpei, Horie, Hiroshi, Makino, Kenta, Wakama, Satoshi, Ito, Takashi, Oshima, Yu, Ogiso, Satoshi, Ishii, Takamichi, Inoue, Masahiro, Hatano, Etsuro

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Aberrant activation of Rho/ROCK signaling in impaired polarity switching of colorectal micropapillary carcinoma von Onuma, Kunishige, Sato, Yumi, Okuyama, Hiroaki, Uematsu, Hiroyuki, Homma, Keiichiro, Ohue, Masayuki, Kondo, Jumpei, Inoue, Masahiro

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Study of glycosylation of prostate-specific antigen secreted by cancer tissue-originated spheroids reveals new candidates for prostate cancer detection von Ideo, Hiroko, Kondo, Jumpei, Nomura, Taisei, Nonomura, Norio, Inoue, Masahiro, Amano, Junko

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A smooth muscle‐derived, Braf‐driven mouse model of gastrointestinal stromal tumor (GIST): evidence for an alternative GIST cell‐of‐origin von Kondo, Jumpei, Huh, Won Jae, Franklin, Jeffrey L, Heinrich, Michael C, Rubin, Brian P, Coffey, Robert J

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Novel ex vivo disease model for extramammary Paget’s disease using the cancer tissue-originated spheroid method von Arita, Takahiro, Kondo, Jumpei, Kaneko, Yuka, Tsutsumi, Miho, Kanemaru, Mai, Matsui, Mari, Arakawa, Yukiyasu, Katoh, Norito, Inoue, Masahiro, Asai, Jun

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Polarity switching of ovarian cancer cell clusters via SRC family kinase is involved in the peritoneal dissemination von Kawata, Mayuko, Kondo, Jumpei, Onuma, Kunishige, Ito, Yu, Yokoi, Takeshi, Hamanishi, Junzo, Mandai, Masaki, Kimura, Tadashi, Inoue, Masahiro

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Tracking the growth fate of single cells and isolating slow-growing cells in human colorectal cancer organoids von Coppo, Roberto, Kondo, Jumpei, Onuma, Kunishige, Inoue, Masahiro

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Inhibition of the bone morphogenetic protein pathway suppresses tumor growth through downregulation of epidermal growth factor receptor in MEK/ERK‐dependent colorectal cancer von Shimizu, Shota, Kondo, Jumpei, Onuma, Kunishige, Coppo, Roberto, Ota, Kasumi, Kamada, Mayumi, Harada, Yohei, Tanaka, Yoshihisa, Nakazawa, Mai Adachi, Tamada, Yoshinori, Okuno, Yasushi, Kawada, Kenji, Obama, Kazutaka, Coffey, Robert J., Fujiwara, Yoshiyuki, Inoue, Masahiro

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The specific core fucose-binding lectin Pholiota squarrosa lectin (PhoSL) inhibits hepatitis B virus infection in vitro von Ouchida, Tsunenori, Maeda, Haruka, Akamatsu, Yuka, Maeda, Megumi, Takamatsu, Shinji, Kondo, Jumpei, Misaki, Ryo, Kamada, Yoshihiro, Ueda, Masahiro, Ueda, Keiji, Miyoshi, Eiji

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Hydrodynamic stress stimulates growth of cell clusters via the ANXA1/PI3K/AKT axis in colorectal cancer von Hagihara, Takeshi, Kondo, Jumpei, Endo, Hiroko, Ohue, Masayuki, Sakai, Yoshiharu, Inoue, Masahiro

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Lewis glycosphingolipids as critical determinants of TRAIL sensitivity in cancer cells von Fukuoka, Tomoya, Moriwaki, Kenta, Takamatsu, Shinji, Kondo, Jumpei, Tanaka-Okamoto, Miki, Tomioka, Azusa, Semba, Manami, Komazawa-Sakon, Sachiko, Kamada, Yoshihiro, Kaji, Hiroyuki, Miyamoto, Yasuhide, Inoue, Masahiro, Bessho, Kazuhiko, Miyoshi, Yoko, Ozono, Keiichi, Nakano, Hiroyasu, Miyoshi, Eiji

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Vesicular Integral-Membrane Protein 36 Is Involved in the Selective Secretion of Fucosylated Proteins into Bile Duct-like Structures in HepG2 Cells von Muranaka, Mizuki, Takamatsu, Shinji, Ouchida, Tsunenori, Kanazawa, Yuri, Kondo, Jumpei, Nakagawa, Tsutomu, Egashira, Yuriko, Fukagawa, Koji, Gu, Jianguo, Okamoto, Toru, Kamada, Yoshihiro, Miyoshi, Eiji

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