Validation of a New Methodology to Create Oral Drugs beyond the Rule of 5 for Intracellular Tough Targets von Ohta, Atsushi, Tanada, Mikimasa, Shinohara, Shojiro, Morita, Yuya, Nakano, Kazuhiko, Yamagishi, Yusuke, Takano, Ryusuke, Kariyuki, Shiori, Iida, Takeo, Matsuo, Atsushi, Ozeki, Kazuhisa, Emura, Takashi, Sakurai, Yuuji, Takano, Koji, Higashida, Atsuko, Kojima, Miki, Muraoka, Terushige, Takeyama, Ryuuichi, Kato, Tatsuya, Kimura, Kaori, Ogawa, Kotaro, Ohara, Kazuhiro, Tanaka, Shota, Kikuchi, Yasufumi, Hisada, Nozomi, Hayashi, Ryuji, Nishimura, Yoshikazu, Nomura, Kenichi, Tachibana, Tatsuhiko, Irie, Machiko, Kawada, Hatsuo, Torizawa, Takuya, Murao, Naoaki, Kotake, Tomoya, Tanaka, Masahiko, Ishikawa, Shiho, Miyake, Taiji, Tamiya, Minoru, Arai, Masako, Chiyoda, Aya, Akai, Sho, Sase, Hitoshi, Kuramoto, Shino, Ito, Toshiya, Shiraishi, Takuya, Kojima, Tetsuo, Iikura, Hitoshi

Volltext

Identification and multidimensional optimization of an asymmetric bispecific IgG antibody mimicking the function of factor VIII cofactor activity von Sampei, Zenjiro, Igawa, Tomoyuki, Soeda, Tetsuhiro, Okuyama-Nishida, Yukiko, Moriyama, Chifumi, Wakabayashi, Tetsuya, Tanaka, Eriko, Muto, Atsushi, Kojima, Tetsuo, Kitazawa, Takehisa, Yoshihashi, Kazutaka, Harada, Aya, Funaki, Miho, Haraya, Kenta, Tachibana, Tatsuhiko, Suzuki, Sachiyo, Esaki, Keiko, Nabuchi, Yoshiaki, Hattori, Kunihiro

Volltext

A bispecific antibody to factors IXa and X restores factor VIII hemostatic activity in a hemophilia A model von Kitazawa, Takehisa, Igawa, Tomoyuki, Sampei, Zenjiro, Muto, Atsushi, Kojima, Tetsuo, Soeda, Tetsuhiro, Yoshihashi, Kazutaka, Okuyama-Nishida, Yukiko, Saito, Hiroyuki, Tsunoda, Hiroyuki, Suzuki, Tsukasa, Adachi, Hideki, Miyazaki, Taro, Ishii, Shinya, Kamata-Sakurai, Mika, Iida, Takeo, Harada, Aya, Esaki, Keiko, Funaki, Miho, Moriyama, Chifumi, Tanaka, Eriko, Kikuchi, Yasufumi, Wakabayashi, Tetsuya, Wada, Manabu, Goto, Masaaki, Toyoda, Takeshi, Ueyama, Atsunori, Suzuki, Sachiyo, Haraya, Kenta, Tachibana, Tatsuhiko, Kawabe, Yoshiki, Shima, Midori, Yoshioka, Akira, Hattori, Kunihiro

Volltext

Deficiency of the Erc/mesothelin gene ameliorates renal carcinogenesis in Tsc2 knockout mice von Zhang, Danqing, Kobayashi, Toshiyuki, Kojima, Tetsuo, Kanenishi, Kenji, Hagiwara, Yoshiaki, Abe, Masaaki, Okura, Hidehiro, Hamano, Yoshitomo, Sun, Guodong, Maeda, Masahiro, Jishage, Kou‐ichi, Noda, Tetsuo, Hino, Okio

Volltext

Long-term follow-up on the use of vascularized fibular graft for the treatment of congenital pseudarthrosis of the tibia von Sakamoto, Akio, Yoshida, Tatsuya, Uchida, Yoshio, Kojima, Tetsuo, Kubota, Hideaki, Iwamoto, Yukihide

Volltext

TROY, a Newly Identified Member of the Tumor Necrosis Factor Receptor Superfamily, Exhibits a Homology with Edar and Is Expressed in Embryonic Skin and Hair Follicles von Kojima, Tetsuo, Morikawa, Yoshihiro, Copeland, Neal G., Gilbert, Debra J., Jenkins, Nancy A., Senba, Emiko, Kitamura, Toshio

Volltext

High-brightness 138-W green laser based on an intracavity-frequency-doubled diode-side-pumped Q-switched Nd:YAG laser von Konno, Susumu, Kojima, Tetsuo, Fujikawa, Shuichi, Yasui, Koji

Volltext

Antibody recycling by engineered pH-dependent antigen binding improves the duration of antigen neutralization von Igawa, Tomoyuki, Ishii, Shinya, Tachibana, Tatsuhiko, Maeda, Atsuhiko, Higuchi, Yoshinobu, Shimaoka, Shin, Moriyama, Chifumi, Watanabe, Tomoyuki, Takubo, Ryoko, Doi, Yoshiaki, Wakabayashi, Tetsuya, Hayasaka, Akira, Kadono, Shoujiro, Miyazaki, Takuya, Haraya, Kenta, Sekimori, Yasuo, Kojima, Tetsuo, Nabuchi, Yoshiaki, Aso, Yoshinori, Kawabe, Yoshiki, Hattori, Kunihiro

Volltext

Structure-activity relationships of middle-size cyclic peptides, KRAS inhibitors derived from an mRNA display von Kage, Mirai, Hayashi, Ryuji, Matsuo, Atsushi, Tamiya, Minoru, Kuramoto, Shino, Ohara, Kazuhiro, Irie, Machiko, Chiyoda, Aya, Takano, Koji, Ito, Toshiya, Kotake, Tomoya, Takeyama, Ryuuichi, Ishikawa, Shiho, Nomura, Kenichi, Furuichi, Noriyuki, Morita, Yuya, Hashimoto, Satoshi, Kawada, Hatsuo, Nishimura, Yoshikazu, Nii, Keiji, Sase, Hitoshi, Ohta, Atsushi, Kojima, Tetsuo, Iikura, Hitoshi, Tanada, Mikimasa, Shiraishi, Takuya

Volltext

20-W ultraviolet-beam generation by fourth-harmonic generation of an all-solid-state laser von Kojima, Tetsuo, Konno, Susumu, Fujikawa, Shuichi, Yasui, Koji, Yoshizawa, Kenji, Mori, Yusuke, Sasaki, Takatomo, Tanaka, Mitsuhiro, Okada, Yukikatsu

Volltext

Aggressive active mobilization following zone II flexor tendon repair using a two-strand heavy-gauge locking loop technique von Hatanaka, Hitoshi, Kojima, Tetsuo, Mizoguchi, Tomoyuki, Ueshin, Yoshifumi

Volltext

Molecular Cloning and Expression of Megakaryocyte Potentiating Factor cDNA (∗) von Kojima, Tetsuo, Oh-eda, Masayoshi, Hattori, Kunihiro, Taniguchi, Yoshiko, Tamura, Masahiko, Ochi, Norimichi, Yamaguchi, Nozomi

Volltext

Molecular cloning of a novel type 1 cytokine receptor similar to the common gamma chain von Fujio, Keishi, Nosaka, Tetsuya, Kojima, Tetsuo, Kawashima, Toshiyuki, Yahata, Takashi, Copeland, Neal G., Gilbert, Debra J., Jenkins, Nancy A., Yamamoto, Kazuhiko, Nishimura, Takashi, Kitamura, Toshio

Volltext

Identification of Novel Membrane and Secreted Proteins Upregulated during Adipocyte Differentiation von Tsuruga, Hiromichi, Kumagai, Hidetoshi, Kojima, Tetsuo, Kitamura, Toshio

Volltext

Non-antigen-contacting region of an asymmetric bispecific antibody to factors IXa/X significantly affects factor VIII-mimetic activity von Sampei, Zenjiro, Igawa, Tomoyuki, Soeda, Tetsuhiro, Funaki, Miho, Yoshihashi, Kazutaka, Kitazawa, Takehisa, Muto, Atsushi, Kojima, Tetsuo, Nakamura, Satoshi, Hattori, Kunihiro

Volltext

Diode-pumped 1 kW Q-switched Nd:YAG rod laser with high peak power and high beam quality von Furuta, Keisuke, Kojima, Tetsuo, Fujikawa, Shuichi, Nishimae, Jun-ichi

Volltext

Endomucin Is Expressed in Embryonic Dorsal Aorta and Is Able to Inhibit Cell Adhesion von Ueno, Masaya, Igarashi, Katsuhide, Kimura, Naoki, Okita, Keisuke, Takizawa, Makiko, Nobuhisa, Ikuo, Kojima, Tetsuo, Kitamura, Toshio, Samulowitz, Ulrike, Vestweber, Dietmar, Shimomura, Taizo, Suda, Toshio, Nakashima, Kinichi, Taga, Tetsuya

Volltext

A signal sequence trap based on a constitutively active cytokine receptor von Kitamura, Toshio, Kojima, Tetsuo

Volltext

Generation of a Novel Bispecific Antibody (ACE910) Against Activated Factor IX and Factor X Mimicking the Function of Factor VIII Cofactor Activity von Igawa, Tomoyuki, Sampei, Zenjiro, Soeda, Tetsuhiro, Okuyama-Nishida, Yukiko, Moriyama, Chifumi, Wakabayashi, Tetsuya, Tanaka, Eriko, Muto, Atsushi, Kojima, Tetsuo, Kitazawa, Takehisa, Yoshihashi, Kazutaka, Harada, Aya, Funaki, Miho, Haraya, Kenta, Tatsuhiko, Tachibana, Suzuki, Sachiyo, Esaki, Keiko, Nabuchi, Yoshiaki, Hattori, Kunihiro

Volltext

Deficiency of the Erclmesothelin gene ameliorates renal carcinogenesis in Tsc2 knockout mice von DANQING ZHANG, KOBAYASHI, Toshiyuki, JISHAGE, Kou-Ichi, NODA, Tetsuo, HINO, Okio, KOJIMA, Tetsuo, KANENISHI, Kenji, HAGIWARA, Yoshiaki, ABE, Masaaki, OKURA, Hidehiro, HAMANO, Yoshitomo, GUODONG SUN, MAEDA, Masahiro

Volltext