Advances in TRP channel drug discovery: from target validation to clinical studies von Koivisto, Ari-Pekka, Belvisi, Maria G., Gaudet, Rachelle, Szallasi, Arpad

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Targeting TRP Channels for Pain, Itch and Neurogenic Inflammation von Koivisto, Ari-Pekka, Szallasi, Arpad

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Targeting TRP channels for pain relief: A review of current evidence from bench to bedside von Koivisto, Ari-Pekka, Voets, Thomas, Iadarola, Michael J., Szallasi, Arpad

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Advances in TRP channel drug discovery: from target validation to clinical studies von Koivisto, Ari-Pekka, Belvisi, Maria G., Gaudet, Rachelle, Szallasi, Arpad

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Inhibition of Canonical Transient Receptor Potential Channels 4/5 with Highly Selective and Potent Small-Molecule HC-070 Alleviates Mechanical Hypersensitivity in Rat Models of Vis... von Jalava, Niina, Kaskinoro, Janne, Chapman, Hugh, Morales, Miguel, Metsänkylä, Hanna, Heinonen, Satu-Maarit, Koivisto, Ari-Pekka

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Discovery and characterization of ORM‐11372, a novel inhibitor of the sodium‐calcium exchanger with positive inotropic activity von Otsomaa, Leena, Levijoki, Jouko, Wohlfahrt, Gerd, Chapman, Hugh, Koivisto, Ari‐Pekka, Syrjänen, Kaisa, Koskelainen, Tuula, Peltokorpi, Saara‐Elisa, Finckenberg, Piet, Heikkilä, Aira, Abi‐Gerges, Najah, Ghetti, Andre, Miller, Paul E., Page, Guy, Mervaala, Eero, Nagy, Norbert, Kohajda, Zsófia, Jost, Norbert, Virág, László, Varró, András, Papp, Julius Gy

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TRPA1 Antagonists for Pain Relief von Koivisto, Ari, Jalava, Niina, Bratty, Raymond, Pertovaara, Antti

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Indirect involvement of α2-adrenoceptors in the mechanical antihypersensitivity effect induced by the spinally administered imidazoline I1 receptor ligand LNP599 in a rat model of... von Wei, Hong, Vuorenpää, Anne, Laurila, Jonne, Domanskyi, Andrii, Koivisto, Ari, Pertovaara, Antti

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Model for long QT syndrome type 2 using human iPS cells demonstrates arrhythmogenic characteristics in cell culture von Lahti, Anna L, Kujala, Ville J, Chapman, Hugh, Koivisto, Ari-Pekka, Pekkanen-Mattila, Mari, Kerkelä, Erja, Hyttinen, Jari, Kontula, Kimmo, Swan, Heikki, Conklin, Bruce R, Yamanaka, Shinya, Silvennoinen, Olli, Aalto-Setälä, Katriina

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Insights Into Molecular Interactions and Biological Effect of Natural Stilbenoids at The TRPA1 Ion Channel von Saadabadi, Atefeh, Rantanen, Marja, Marimuthu, Parthiban, Koivisto, Ari-Pekka, Eklund, Patrik C, Salo-Ahen, Outi M H

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Spinal TRPA1 Contributes to the Mechanical Hypersensitivity Effect Induced by Netrin-1 von Wei, Hong, Ailanen, Liisa, Morales, Miguel, Koivisto, Ari, Pertovaara, Antti

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TRPA1 ion channel in the spinal dorsal horn as a therapeutic target in central pain hypersensitivity and cutaneous neurogenic inflammation von Pertovaara, Antti, Koivisto, Ari

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TRPA1: A Transducer and Amplifier of Pain and Inflammation von Koivisto, Ari, Chapman, Hugh, Jalava, Niina, Korjamo, Timo, Saarnilehto, Marja, Lindstedt, Ken, Pertovaara, Antti

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Regulation of neuropathic pain behavior by amygdaloid TRPC4/C5 channels von Wei, Hong, Sagalajev, Boriss, Yüzer, M. Anil, Koivisto, Ari, Pertovaara, Antti

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Attenuation of Mechanical Hypersensitivity by an Antagonist of the TRPA1 Ion Channel in Diabetic Animals von HONG WEI, HÄMÄLÄINEN, Minna M, SAARNILEHTO, Marja, KOIVISTO, Ari, PERTOVAARA, Antti

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Transient Receptor Potential Ankyrin 1 Ion Channel Contributes to Guarding Pain and Mechanical Hypersensitivity in a Rat Model of Postoperative Pain von HONG WEI, KARIMAA, Mari, KORJAMO, Timo, KOIVISTO, Ari, PERTOVAARA, Antti

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Inhibiting TRPA1 ion channel reduces loss of cutaneous nerve fiber function in diabetic animals: Sustained activation of the TRPA1 channel contributes to the pathogenesis of periph... von Koivisto, Ari, Hukkanen, Mika, Saarnilehto, Marja, Chapman, Hugh, Kuokkanen, Katja, Wei, Hong, Viisanen, Hanna, Åkerman, Karl E., Lindstedt, Ken, Pertovaara, Antti

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Roles of cutaneous versus spinal TRPA1 channels in mechanical hypersensitivity in the diabetic or mustard oil-treated non-diabetic rat von Wei, Hong, Chapman, Hugh, Saarnilehto, Marja, Kuokkanen, Katja, Koivisto, Ari, Pertovaara, Antti

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Spinal transient receptor potential ankyrin 1 channel contributes to central pain hypersensitivity in various pathophysiological conditions in the rat von Wei, Hong, Koivisto, Ari, Saarnilehto, Marja, Chapman, Hugh, Kuokkanen, Katja, Hao, Bin, Huang, Jin-Lu, Wang, Yong-Xiang, Pertovaara, Antti

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Human embryonic stem cell-derived cardiomyocytes: demonstration of a portion of cardiac cells with fairly mature electrical phenotype von Pekkanen-Mattila, Mari, Chapman, Hugh, Kerkelä, Erja, Suuronen, Riitta, Skottman, Heli, Koivisto, Ari-Pekka, Aalto-Setälä, Katriina

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